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Investigation of conformational changes of cathepsin B as a feasibility assessment for NaCl reduction in Jinhua ham

Food Science and Human Wellness 2025年第2期14卷 429-438页

作者： Shiqi Hu Guanghong Zhou Xinglian Xu Wangang Zhang Chunbao Li Key Laboratory of Meat Processing and Quality Control Ministry of EducationKey Laboratory of Meat ProcessingMinistry of Agriculture and Rural AffairsJiangsu Synergetic Innovation Center of Meat Processing and Quality ControlCollege of Food Science and TechnologyNanjing Agricultural UniversityNanjing 210095China School of Life Science and Food Engineering Huaiyin Institute of TechnologyHuai’an 223003China

To regulate the sodium chloride content in Jinhua ham,the impact of NaCl on the activity and conformation of cathepsin B was investigated using spectroscopy and computational *** results showed that the activity of cathepsin B decreased with an increase in Na^(+)cation content and ***,decreasedα-helix content and increasedβ-sheet content were *** increase in sulfhydryl group content was attributed to the breaking of original disulfide bonds in the molecular structure or the release of embedded ***,the surface hydrophobicity gradually declined,which was consistent with the analysis of endogenous fluorescence *** the molecular level,the number of hydrogen bonds formed in NaCl-treated samples decreased,and the interactions between the hydrogen bonding were less powerful,which caused instability in the binding of the protein and *** conformation of cathepsin B accurately characterized its activity,and the structural changes had a macroscopic effect on the decrease in protease activity.

关键词： Protein conformation Cathepsin B activity Jinhua ham Molecular docking Molecular dynamics

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Stability and Stabilization of Sampled-Data Based LFC for Power Systems:A Data-Driven Method

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IEEE/CAA Journal of Automatica Sinica 2025年第1期12卷 291-293页

作者： Yu-Long Fan Chuan-Ke Zhang Yong He the School of Automation China University of Geosciences the Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systems the Engineering Research Center of Intelligent Technology for Geo-Exploration Ministry of Education IEEE

Dear Editor,This letter is concerned with stability analysis and stabilization design for sampled-data based load frequency control(LFC) systems via a data-driven method. By describing the dynamic behavior of LFC systems based on a data-based representation, a stability criterion is derived to obtain the admissible maximum sampling interval(MSI) for a given controller and a design condition of the PI-type controller is further developed to meet the required MSI. Finally, the effectiveness of the proposed methods is verified by a case study.

关键词： Sampled data control systems

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Stability analysis of karst anti dip rock slope induced by underground coal mining——A case study of Jiguanling landslide, China

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Journal of Mountain Science 2025年第4期22卷 1226-1244页

作者： ZHONG Zuliang LIANG Erwei WANG Nanyun XU Yawei School of Civil Engineering Chongqing UniversityChongqing 400045China State key laboratory of coal mine disaster dynamics and control Chongqing 400044China Key Laboratory of New Technology for Construction of Cities in Mountain Area of Ministry of Education Chongqing 400045China

In recent years,the southwestern region of China has experienced a surge in significant mountain collapses,predominantly linked to underground mining *** investigation targets the Jiguanling area in Wulong,Chongqing,employing the UDEC numerical simulation technique to meticulously examine the deformation and failure characteristics,rock mass movement patterns,fracture evolution processes,and stress transmission mechanisms of anti-dip rock slopes composed of stratified *** slopes are inherently susceptible to bending and tilting due to their own *** findings elucidate that the predominant failure mode of anti-dip rock karst slopes is the inclined sliding(shear)type,which mirrors the fracture evolution mechanism as they extend in a quadrilateral pattern from the top and bottom plates of the mining area to the critical blocks at the rear and front edges of the *** disaster mechanism can be encapsulated as the"initial roof movement phase,direct roof collapse and crack propagation phase,critical block locking and sliding resistance phase,and deterioration phase".The four distinct stages of development and transformation encompass critical block slip(shear)and slope instability *** increase in coal seam thickness enlarges the deformation space in the lower part,while the dip angle of the coal seam influences the length and displacement range of rock fracture *** mining sequence alters the stress failure mode of the underlying critical blocks,and the vertical height of the mining step distance modifies the potential sliding surface and failure mode of the underlying critical ***,the distance between the goaf and the surface,along with the height of the mining impact,impacts the stability of the reverse *** results demonstrate that mining activities are the primary factor inducing the collapse of anti-dip rock slopes,with natural factors playing a secondary role.

关键词： Anti-dip rock slope Mining action Slope deformation mechanism Slope instability mechanism Evolution law of cracks

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Risk-Targeted Design Spectra for Uniform Risk Seismic Design

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Seismological Research Letters 2025年第3期96卷 1820-1833页

作者： Wang, Cong Lu, Da-Gang Key Laboratory of Building Structural Retrofitting and Underground Space Engineering Ministry of Education Shandong Jianzhu University Jinan China Key Laboratory of Structural Dynamic Behaviors and Control Ministry of Education Harbin Institute of Technology Harbin China

The uniform hazard response spectrum only considers the seismic hazard of a site, without taking into account the seismic fragility of the structure. As a result, structures designed based on this spectrum may exhibit varying levels of collapse risk under earthquakes in different regions. To this end, first, various cases are employed to determine a first-order approximation of the seismic hazard function H(x), followed by a validation of its rationality. Subsequently, with the objective of achieving uniform collapse risk, considering both seismic hazard and structural fragility, single anchor point, double anchor points, and multiple anchor points methods are proposed to construct the risk-targeted seismic design spectra for frequent earthquake (FE), design basis earthquake (DBE), maximum considered earthquake (MCE), and very rare earthquake (VRE). Furthermore, a comprehensive study is conducted to analyze the risk-targeted seismic design spectra corresponding to different seismic design levels, site classes, and characteristic periods constructed using the multiple anchor points method. In addition, a comparative analysis is conducted on the risk-targeted seismic design spectra constructed using different methods. The study indicates that determining H(x) based on DBE and VRE is reasonable, and the relative difference between the risk-targeted ground motion (RTGM) derived from this case and the RTGM obtained by determining H(x) based on probabilistic seismic hazard analysis is within 4%. The risk-targeted seismic design spectra constructed using three different methods show overall similarity. The single anchor point method offers simplicity in calculations and ensures that the uniform risk seismic design spectrum aligns with the uniform hazard seismic design spectrum in terms of spectral shape. Although the multiple anchor points method involves increased computational effort, it allows for the consideration of seismic hazard at multiple periods. © Seismological

关键词： Risk assessment

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Parallel Path-Following control of Fully-Actuated Autonomous Surface Vehicles Based on a High-Order Learning Extended State Observer

Parallel Path-Following Control of Fully-Actuated Autonomous...

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International Conference on Artificial Intelligence and Autonomous Transportation, AIAT 2024

作者： Xu, Jiaxue Liu, Haodong Gu, Nan Liu, Lu Peng, Zhouhua School of Marine Electrical Engineering Dalian Maritime University Dalian116026 China Dalian Key Laboratory of Swarm Control and Electrical Technology for Intelligent Ships Dalian116026 China State Key Laboratory of Maritime Technology and Safety Dalian China

ISBN: (纸本)9789819639724

Unlike traditional path-following methods, this paper develops a parallel control framework to investigate the path-following behavior of autonomous surface ships (ASVs) in the presence of unknown disturbances and model uncertainties. Specifically, a high-order learning extended state observer is proposed to construct a digital-twin ASV system, enabling precise depiction of the motion characteristics of the actual ASV system. Based on the states and unknown total disturbances estimated by the digital-twin ASV system, a parallel path-following controller is developed to actively guide the ASV to achieve path-following task. Simulation results validate the efficacy of the proposed parallel path-following control scheme for the fully-actuated ASV. © Beijing Paike Culture Commu. Co., Ltd. 2025.

关键词： State estimation

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Research and Design of AIS Reception Signal Processing System Based on GNU Radio 27

Research and Design of AIS Reception Signal Processing Syste...

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27th International Conference on Advanced Communications technology, ICACT 2025

作者： Zhou, Zijiao Gong, Peng Tang, Bin He, Piao Peng, Xiuming Zhang, Guangwei National Key Laboratory of Mechatronic Engineering and Control School of Mechatronical Engineering Beijing Institute of Technology Beijing China

ISBN: (纸本)9791188428137

The Automatic Identification System (AIS), as a standard communication and navigation device for ships, plays a significant role in ensuring the safety and efficiency of maritime traffic. The accuracy of the AIS receiver’s signal processing directly affects the bit error rate (BER) and packet error rate (PER) of the AIS system, drawing considerable attention to AIS signal reception and processing technologies. Current research on AIS reception signals mainly focuses on custom implementations using hardware platforms like FPGAs;however, the high cost of hardware implementation has become a limiting factor in the development of AIS signal processing technologies. Therefore, this paper designs an AIS reception signal processing system based on GNU Radio, developing demodulation algorithm and NRZI decoding modules, and testing them with typical demodulation algorithms. Experimental results demonstrate the feasibility and effectiveness of the designed reception signal processing system. Copyright 2025 Global IT Research Institute (GIRI). All rights reserved.

关键词： Decoding

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Prediction of time-energy-location of microseismic events induced by deep coal-energy mining:Deep learning approach

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Journal of Rock Mechanics and Geotechnical engineering 2025年第1期17卷 233-244页

作者： Yue Song Enyuan Wang Hengze Yang Dong Chen Baolin Li Yangyang Di School of Safety Engineering China University of Mining and TechnologyXuzhou221116China State Key Laboratory of Coal Mine Disaster Prevention and Control China University of Mining and TechnologyXuzhou221116China State Key Laboratory for Geomechanics&Deep Underground Engineering China University of Mining TechnologyXuzhou221116China School of Environment and Safety Engineering North University of ChinaTaiyuan030051China School of Materials Engineering Changshu Institute of TechnologySuzhou215506China

Deep coal-energy mining frequently results in microseismic(MS)events,which may be a precursor to the risk of rockbursts and pose risks to human safety and ***,quantitatively predicting the time,energy,and location(TEL)of future MS events is crucial for understanding and preventing potential catastrophic *** this study,we introduced the application of spatiotemporal graph convolutional networks(STGCN)to predict the TEL of MS events induced by deep coal-energy ***,this was the first application of graph convolution networks(GCNs)in the spatiotemporal prediction of MS *** adjacency matrices of the sensor networks were determined based on the distance between MS sensors,the sensor network graphs we constructed,and GCN was employed to extract the spatiotemporal details of the *** model is simple and *** testing the model with on-site MS monitoring data,our results demonstrated promising efficacy in predicting the TEL of MS events,with the cosine similarity(C)above 0.90 and the mean relative error(MRE)below *** is critical to improving the safety and operational efficiency of deep coal-energy mining.

关键词： Rockburst Microseismic system Monitoring and early warning Artificial intelligence

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Safety-Critical control of Autonomous Surface Vehicles for Collaborative Transportation Based on Quadratic Programming

Safety-Critical Control of Autonomous Surface Vehicles for C...

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International Conference on Artificial Intelligence and Autonomous Transportation, AIAT 2024

作者： Liu, Haodong Xu, Jiaxue Wang, Anqing Gu, Nan Liu, Lu Peng, Zhouhua School of Marine Electrical Engineering Dalian Maritime University Dalian116026 China Dalian Key Laboratory of Swarm Control and Electrical Technology for Intelligent Ships Dalian116026 China State Key Laboratory of Maritime Technology and Safety Dalian China

ISBN: (纸本)9789819639687

This paper addresses collaborative transportation of autonomous surface vehicles (ASVs) operating at a low speed in an open water area to assist in the movement of a ship. A constrained collaborative control method is proposed for ASVs based on a kinematic model. During the collaborative transportation phase, each ASV can converge to the desired position-heading by designing a safety-critical kinematic control law. To achieve the collaborative transportation of ASVs, the collaborative velocity signals are obtained by solving a quadratic programming problem subject to the contact force constraint and the assisted ship constraints such that the safety of ASVs during collaborative transportation can be ensured. By using the proposed constrained collaborative control method, the collaborative transportation of ASVs can be achieved. Simulation results are shown to validate the efficacy of the proposed constrained collaborative control method for collaborative transportation of ASVs. © Beijing Paike Culture Commu. Co., Ltd. 2025.

关键词： Quadratic programming

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Anti-Jamming Weighted Clustering Algorithm for UAV-Mounted Weapon Self-Organizing Network 27

Anti-Jamming Weighted Clustering Algorithm for UAV-Mounted W...

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27th International Conference on Advanced Communications technology, ICACT 2025

作者： Li, Siqi Gao, Xiang Liu, Yuhan He, Piao Ji, Jianing Gong, Peng National Key Laboratory of Mechatronic Engineering and Control School of Mechatronical Engineering Beijing Institute of Technology Beijing China

ISBN: (纸本)9791188428137

Compared to traditional self-organizing networks, UAV-mounted weapon self-organizing networks are characterized by high node mobility, vulnerability to interference and attacks, extensive coverage, and large-scale network sizes. These factors complicate network management and the operation of routing protocols. Cluster-based topologies can be employed to optimize network management, reducing the impact of local topology changes on the entire network. To address the issue of cluster instability caused by the high mobility and interference susceptibility of UAV-mounted weapons, a anti-jamming weighted clustering algorithm(AJWCA) is proposed. The algorithm builds on existing weighted clustering approaches by incorporating an interference factor into the cluster head selection process. Additionally, a backup cluster head mechanism is introduced to mitigate cluster oscillations resulting from the failure of cluster head nodes in battlefield and emergency scenarios. The effectiveness of the proposed algorithm was validated through simulations. The results show that the algorithm effectively enables efficient clustering of network nodes and improves cluster head duration under interference conditions. Moreover, the method demonstrates rapid recovery capability in the event of node failures, making it well-suited for deployment in complex operational environments. © 2025 Institute of Electrical and Electronics Engineers Inc.. All rights reserved.

关键词： Jamming

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A Cogging Torque Suppression Algorithm Based on Model Predictive control 27

A Cogging Torque Suppression Algorithm Based on Model Predic...

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27th International Conference on Advanced Communications technology, ICACT 2025

作者： Gao, Peng Gong, Peng Tang, Bin He, Piao Ji, Jianing Zhang, Guangwei National Key Laboratory of Mechatronic Engineering and Control School of Mechatronical Engineering Beijing Institute of Technology Beijing China

ISBN: (纸本)9791188428137

Cogging torque is a unique issue in the servo systems of permanent magnet synchronous motor (PMSM) and a key problem that must be addressed in the design and manufacturing of high-performance permanent magnet motors. Due to their inherent structural characteristics, PMSMs inevitably produce cogging torque, which leads to disturbances and noise, particularly detrimental to motor control systems operating at low speeds. Additionally, the presence of cogging torque affects the positioning accuracy of the rotor at any given moment. This paper presents a high-quality control method for suppressing cogging torque. The proposed cogging torque suppression strategy is studied through simulations and compared with traditional cogging torque suppression strategies. The simulation results indicate that the proposed high-precision positioning servo control method is effective in suppressing cogging torque. Copyright 2025 Global IT Research Institute (GIRI). All rights reserved.

关键词： Permanent magnets

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