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Prediction of Drug-Disease Associations Based on Long Short-Term Memory Network and Gaussian Interaction Profile Kernel 15th

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Prediction of Drug-Disease Associations Based on Long Short-...

15th International Conference on Bio-Inspired Computing: Theories and Applications, BIC-TA 2020

作者： Jiang, Han-Jing Wang, Yan-Bin Huang, Yabing Key Laboratory of Image Information Processing and Intelligent Control of Education Ministry of China Institute of Artificial Intelligence School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China College of Computer Science and Technology Zhejiang University Hangzhou315000 China Department of Pathology Renmin Hospital of Wuhan University Wuhan430060 China

ISBN: (纸本)9789811613531

Drug-disease association depicts the accessibility landscape of the association at the molecular level, thereby revealing the intermolecular reaction in the process of drug reposition. However, the scarcity of drug-disease association data often complicates the drug reposition. In this work, we present a method for predicting drug-disease association, which is called drug-disease association prediction via Gaussian interaction profile kernel and long short-term memory network (G-LSTM). G-LSTM combines a recurrent network framework with a Gaussian interaction profile kernel to learn underlying features that accurately characterize drug-disease-association data. We have verified G-LSTM models on the two benchmark datasets Fdataset and Cdataset, respectively. The experimental results show that the predictive performance was significantly improved, with AUC of 0.9527 and 0.9705, respectively. © 2021, Springer Nature Singapore Pte Ltd.

关键词： Long short-term memory

Prognostic Prediction for Non-small-Cell Lung Cancer Based on Deep Neural Network and Multimodal Data 17th

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Prognostic Prediction for Non-small-Cell Lung Cancer Based o...

17th International Conference on intelligent Computing, ICIC 2021

作者： Zhang, Zhong-Si Xu, Fei Jiang, Han-Jing Chen, Zhan-Heng Key Laboratory of Image Information Processing and Intelligent Control of Education Ministry of China Institute of Artificial Intelligence School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China Institute of Machine Learning and Systems Biology School of Electronics and Information Engineering Tongji University No. 4800 Caoan Road Shanghai201804 China

ISBN: (纸本)9783030845315

Non-small-cell lung cancer (NSCLC) is the most common lung cancer with poor prognosis. Prognostic prediction is significant in improving the prognosis of NSCLC patients. Clinical information and multi-omics data including gene expression, miRNA, copy number variations, and DNA methylation are closely related to NSCLC prognosis. In this study, we propose a deep neural network to conduct prognostic prediction for NSCLC patients based on all five types of data. Given the high dimensional features of the omics data, past works reduce the feature dimension by regression analysis or correlation sorting algorithms. A shortcoming of these methods is that only a small number of features are considered. To overcome it, we propose a convolution neural network-based feature transformation method, which considers all features and extracts the abstract representations of the omics data. Based on the representations, we predict the five-year survival status of NSCLC patients. The results show that our method achieves a more precise prediction than previous work, with the areas under the curve improved from 0.8163 to 0.8508 and the accuracy improved from 0.7544 to 0.8096. © 2021, Springer Nature Switzerland AG.

关键词： Forecasting

Direction-Constrained control for Efficient Physical Human-Robot Interaction under Hierarchical Tasks

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arXiv

arXiv 2024年

作者： Xu, Mengxin Wan, Weiwei Wang, Hesheng Harada, Kensuke Department of Automation Shanghai Jiao Tong University Shanghai200240 China Department of System Innovation Graduate School of Engineering Science Osaka University Toyonaka Osaka560-0043 Japan Department of Automation the Key Laboratory of System Control and Information Processing of Ministry of Education the Shanghai Engineering Research Center of Intelligent Control and Management Shanghai Jiao Tong University Shanghai200240 China

This paper proposes a control method to address the physical Human-Robot Interaction (pHRI) challenge in the context of hierarchical tasks. A common approach to managing hierarchical tasks is Hierarchical Quadratic Programming (HQP), which, however, cannot be directly applied to human interaction due to its allowance of arbitrary velocity direction adjustments. To resolve this limitation, we introduce the concept of directional constraints and develop a direction-constrained optimization algorithm to handle the nonlinearities induced by these constraints. The algorithm solves two sub-problems, minimizing the error and minimizing the deviation angle, in parallel, and combines the results of the two sub-problems to produce a final optimal outcome. The mutual influence between these two sub-problems is analyzed to determine the best parameter for combination. Additionally, the velocity objective in our control framework is computed using a variable admittance controller. Traditional admittance control does not account for constraints. To address this issue, we propose a variable admittance control method to adjust control objectives dynamically. The method helps reduce the deviation between robot velocity and human intention at the constraint boundaries, thereby enhancing interaction efficiency. We evaluate the proposed method in scenarios where a human operator physically interacts with a 7-degree-of-freedom robotic arm. The results highlight the importance of incorporating directional constraints in pHRI for hierarchical tasks. Compared to existing methods, our approach generates smoother robotic trajectories during interaction while avoiding interaction delays at the constraint boundaries. Copyright © 2024, The Authors. All rights reserved.

关键词： Constrained optimization

Exploiting Distilled Learning for Deep Siamese Tracking

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Exploiting Distilled Learning for Deep Siamese Tracking

International Conference on Pattern Recognition

作者： Chengxin Liu Zhiguo Cao Wei Li Yang Xiao Shuaiyuan Du Angfan Zhu Key Laboratory of Image Processing and Intelligent Control Ministry of Education School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan China Queen Mary University of London

Existing deep siamese trackers are typically built on off-the-shelf CNN models for feature learning, with the demand for huge power consumption and memory storage. This limits current deep siamese trackers to be carried on resource-constrained devices like mobile phones, given factor that such a deployment normally requires cost-effective considerations. In this work, we address this issue by presenting a novel Distilled Learning Framework(DLF) for siamese tracking, which aims at learning tracking model with efficiency and high accuracy. Specifically, we propose two simple yet effective knowledge distillation strategies, denote as point-wise distillation and pairwise distillation, which are designed for transferring knowledge from a more discriminative teacher tracker into a compact student tracker. In this way, cost-effective and high performance tracking could be achieved. Extensive experiments on several tracking benchmarks demonstrate the effectiveness of our proposed method.

关键词： Power demand Pipelines Memory management Benchmark testing Mobile handsets Pattern recognition

Knowledge-Based Scene Text Recognition for Industrial Applications

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Knowledge-Based Scene Text Recognition for Industrial Applic...

IEEE International Conference on Industrial Technology (ICIT)

作者： Guowei Deng Jingzheng Tu Cailian Chen Jianping He Xinyi Le Department of Automation Shanghai Jiao Tong University Shanghai China Key Laboratory of System Control and Information Processing Ministry of Education of China Shanghai China Shanghai Engineering Research Center of Industrial Intelligent Control and Management Shanghai China

ISBN: (纸本)9781728119496

Scene text recognition (STR) methods combined with semantic information have made great progress to recognize texts in natural scenes, most of which are daily words. However, research on mining semantic information in industrial texts attracts less attention. Since industrial texts follow a different semantic pattern defined by industry standards, it challenges many existing methods to conduct accurate semantic reasoning. In this paper, we abstract the industry standards into two aspects of prior knowledge: the grouping property and the prior lexicon. Correspondingly, a knowledge-based language model is proposed with several group-wise correlation modules and a lexicon-based reasoning module to learn semantic rules from both data and the prior knowledge. Besides, we transfer the prior knowledge into data by generating synthetic pure text datasets according to the industry standards’ rules, which introduces more prior knowledge to the language model. Furthermore, a novel STR framework is presented by combining the knowledge-based language model and an attention-based vision model. For evaluation, two industrial text datasets called CIN and SB are collected from real-world industrial field surveillance. Experiments indicate that our method’s word-level accuracy outperforms state-of-the-art methods with 15% and 10.61% on CIN and SB datasets respectively.

关键词： Industries Correlation Text recognition Surveillance Semantics Knowledge based systems Data models

Atf-Bss: Adaptive Time-Frequency Blind Source Separation for High Reverberation and Echo Environments

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SSRN 2023年

作者： Xie, Yuan Zou, Tao Chen, Ci Sun, Weijun Xie, Shengli School of Mechanical and Electrical Engineering Guangzhou University Guangdong-Hong Kong-Macao Key Laboratory of Multi-scale Information Fusion and Collaborative Optimization Control of Complex Manufacturing Process Guangzhou510006 China School of Automation Guangdong University of Technology Joint International Research Laboratory of Intelligent Information Processing and System Integration of IoT Ministry of Education of the P.R.C. Guangzhou510006 China School of Automation Guangdong University of Technology Guangdong Key Laboratory of IoT Information Processing Guangdong-HongKong-Macao Joint Laboratory for Smart Discrete Manufacturing Guangzhou510006 China School of Automation Guangdong University of Technology Key Laboratory of Intelligent Detection and the IoT in Manufacturing Ministry of Education 111 Center for Intelligent Batch Manufacturing Based on IoT Technology Guangzhou510006 China

Blind source separation with high reverberation and echoes is an open and extremely challenging issue. Because the room reverberation and echoes have an important influence on acoustics quality, bringing great difficulty to the independent source separation. In the paper, an adaptive time-frequency blind source separation (ATF-BSS) algorithm is designed to deal with the high reverberation and echoes, which can adaptively attenuate the audible echoes and enhance the harmonic structure of the real-world audio signals, achieving excellent separation performance. Firstly, an equalizer network is designed for the room impulse response to weakening audible echoes under the high reverberation and echo environments without changing the perceived timbre. Furthermore, an adaptive time-frequency Wiener-like masking is presented to enhance the dominant signal and attenuate the other components having less energy than the dominant signal. To the best of our knowledge, this is the first attempt to incorporate the advantages of an equalizer network for removing or weakening audible echoes and adaptive time-frequency masking to solve blind separation with high reverberation and echoes. Experimental results on the public audio datasets demonstrate that the proposed ATF-BSS algorithm improves signal intelligibility and achieves much better separation performance than the state-of-the-art methods. © 2023, The Authors. All rights reserved.

关键词： Reverberation

Room Impulse Response Reshaping-Based Blind Source Separation in an Underdetermined Reverberant Environment

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SSRN 2023年

作者： Xie, Yuan Zou, Tao Yang, Junjie Sun, Weijun Xie, Shengli School of Mechanical and Electrical Engineering Guangzhou University Guangdong-Hong Kong-Macao Key Laboratory of Multi-scale Information Fusion and Collaborative Optimization Control of Complex Manufacturing Process Guangzhou510006 China School of Automation Guangdong University of Technology Joint International Research Laboratory of Intelligent Information Processing and System Integration of IoT Ministry of Education of the P.R.C. Guangzhou510006 China School of Automation Guangdong University of Technology Guangdong Key Laboratory of IoT Information Processing Guangdong-HongKong-Macao Joint Laboratory for Smart Discrete Manufacturing Guangzhou510006 China School of Automation Guangdong University of Technology Key Laboratory of Intelligent Detection and the IoT in Manufacturing Ministry of Education 111 Center for Intelligent Batch Manufacturing Based on IoT Technology Guangzhou510006 China

Blind source separation in an underdetermined reverberation environment is a very challenging issue. The classical method is based on the expectation-maximization algorithm. However, it is limited in a high reverberation environment, resulting in bad or even invalid separation performance. To get rid of this restriction, a room impulse response reshaping-based blind source separation algorithm is designed to solve the signal separation problem in an underdetermined reverberant environment. Firstly, a room impulse response reshaping technology is designed to eliminate the influence of audible echo for the reverberant environment, improving the quality of the received signals. Then, a new mathematical model of time-frequency mixing signals is established to reduce the approximation error of model transformation caused by high reverberation. Furthermore, an improved expectation-maximization algorithm is proposed for real-time update learning rules of model parameters, and then the sources are separated using the estimators provided by the improved expectation maximization method. Experimental results based on source separation of speech and music mixtures demonstrate that the proposed algorithm achieves better separation performance while maintaining much better robustness than the popular expectation-maximization methods. © 2023, The Authors. All rights reserved.

关键词： Blind source separation

Atf-Bss: Adaptive Time-Frequency Blind Source Separation for High Reverberation and Echo Environments

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SSRN 2023年

Blind source separation with high reverberation and echoes is an open and extremely challenging issue. Room reverberation and echoes have an important influence on acoustics quality, causing great difficulty in independent source separation. In the paper, an adaptive time-frequency blind source separation algorithm (ATF-BSS) is designed to deal with high reverberation and echoes, which can adaptively attenuate audible echoes and enhance the harmonic structure of real-world audio signals, achieving excellent separation performance. Firstly, an equalizer network is designed for the room impulse response to weakening audible echoes under high reverberation and echo environments without changing the perceived timbre. Furthermore, an adaptive time-frequency Wiener-like masking is presented to enhance the dominant signal and attenuate the other components that have less energy than the dominant signal. ATF-BSS algorithm incorporates the advantages of an equalizer network for removing or weakening audible echoes and adaptive time-frequency masking for high reverberation and echoes scene, improving the performance of blind separation. Experimental results on public audio datasets demonstrate that the proposed ATF-BSS algorithm improves signal intelligibility and achieves much better separation performance than state-of-the-art methods. © 2023, The Authors. All rights reserved.

关键词： Reverberation

Atf-Bss: Adaptive Time-Frequency Blind Source Separation for High Reverberation and Echo Environments

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SSRN 2023年

Blind source separation with high reverberation and echoes is an open and extremely challenging issue. Room reverberation and echoes have an important influence on acoustics quality, causing great difficulty in independent source separation. In the paper, an adaptive time-frequency blind source separation algorithm (ATF-BSS) is designed to deal with high reverberation and echoes, which can adaptively attenuate audible echoes and enhance the harmonic structure of real-world audio signals, achieving excellent separation performance. Firstly, an equalizer network is designed for the room impulse response to weakening audible echoes under high reverberation and echo environments without changing the perceived timbre. Furthermore, an adaptive time-frequency Wiener-like masking is presented to enhance the dominant signal and attenuate the other components that have less energy than the dominant signal. To the best of our knowledge, this is the first attempt to incorporate the advantages of an equalizer network for removing or weakening audible echoes and adaptive time-frequency masking to solve blind separation with high reverberation and echoes. Experimental results on public audio datasets demonstrate that the proposed ATF-BSS algorithm improves signal intelligibility and achieves much better separation performance than state-of-the-art methods. © 2023, The Authors. All rights reserved.

关键词： Reverberation