The biological immune system is a highly parallel and distributed adaptive system. The information processing abilities of the immune system provide important insights into the field of computation. Based on immunodom...
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The biological immune system is a highly parallel and distributed adaptive system. The information processing abilities of the immune system provide important insights into the field of computation. Based on immunodominance in the biological immune system and the clonal selection mechanism, a novel data mining method, Immune Dominance Clonal Multiobjective Clustering algorithm (IDCMC), is presented. The algorithm divides an individual population into three sub-populations according to three different measurements, and adopts different evolution and selection strategies for each sub-population. The update of each sub-population, however, is not carried out in isolation. The periodic combination operation of the analysis of the three sub-populations represents considerable advantages in its global search ability. The clustering task is a multiobjective optimization problem, which is more robust with respect to the variety of cluster structures of different datasets than a single-objective clustering algorithm. In addition, the new algorithm can determine the number of clusters automatically, which should identify the most promising clustering solutions in the candidate set. The experimental results, using artificial datasets with different manifold structure and handwritten digit datasets, show that the IDCMC outperforms the PESA-Ⅱ-based clustering method, the genetic algorithm-based clustering technique and the original K-Means algorithm in solving most of the problems tested.
The quantum-inspired immune clonal algorithm(QICA) is a rising intelligence *** on evolutionary game theory and QICA,a quantum-inspired immune algorithm embedded with evolutionary game(EGQICA) is proposed to solve com...
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The quantum-inspired immune clonal algorithm(QICA) is a rising intelligence *** on evolutionary game theory and QICA,a quantum-inspired immune algorithm embedded with evolutionary game(EGQICA) is proposed to solve combination optimization *** this paper,we map the quantum antibody’s finding the optimal solution to player’s pursuing maximum utility by choosing strategies in evolutionary *** dynamics is used to model the behavior of the quantum antibody and the memory mechanism is also introduced in this *** results indicate that the proposed approach maintains a good diversity and achieves superior performance.
Membrane proteins are an important kind of proteins embedded in the membranes of cells and play crucial roles in living organisms, such as ion channels,transporters, receptors. Because it is difficult to determinate t...
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Membrane proteins are an important kind of proteins embedded in the membranes of cells and play crucial roles in living organisms, such as ion channels,transporters, receptors. Because it is difficult to determinate the membrane protein's structure by wet-lab experiments,accurate and fast amino acid sequence-based computational methods are highly desired. In this paper, we report an online prediction tool called Mem Brain, whose input is the amino acid sequence. Mem Brain consists of specialized modules for predicting transmembrane helices, residue–residue contacts and relative accessible surface area of a-helical membrane proteins. Mem Brain achieves aprediction accuracy of 97.9% of ATMH, 87.1% of AP,3.2 ± 3.0 of N-score, 3.1 ± 2.8 of C-score. Mem BrainContact obtains 62%/64.1% prediction accuracy on training and independent dataset on top L/5 contact prediction,respectively. And Mem Brain-Rasa achieves Pearson correlation coefficient of 0.733 and its mean absolute error of13.593. These prediction results provide valuable hints for revealing the structure and function of membrane *** Brain web server is free for academic use and available at ***/bioinf/Mem Brain/.
Exploring brain function is crucial for unraveling the pathological mechanism underlying stroke. while most studies focus on brain function emphasize dynamic connections and interactions within or between brain region...
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Tissue P systems are a class of distributed and parallel computing models inspired from inter-cellular communication and cooperation between cells. In this work, a variant of tissue P system, named tissue P system wit...
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Tissue P systems are a class of distributed and parallel computing models inspired from inter-cellular communication and cooperation between cells. In this work, a variant of tissue P system, named tissue P system with look-ahead mode, is discussed for decreasing the inherent non-determinism of tissue P systems and helping implementing tissue P systems on computers. Such systems are proved to be universal by simulating register machine, and they are also proved to be able to efficiently solve computationally hard problems by means of a spacetime tradeoff, which is illustrated with a polynomial solution to 3-coloring problem.
Subcellular localization of proteins can provide key hints to infer their functions and structures in cells. With the breakthrough of recent molecule imaging techniques, the usage of 2D bioimages has become increasing...
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Subcellular localization of proteins can provide key hints to infer their functions and structures in cells. With the breakthrough of recent molecule imaging techniques, the usage of 2D bioimages has become increasingly popular in automatically analyzing the protein subcellular location pat- terns. Compared with the widely used protein 1D amino acid sequence data, the images of protein distribution are more intuitive and interpretable, making the images a better choice at many applications for revealing the dynamic char- acteristics of proteins, such as detecting protein translocation and quantification of proteins. In this paper, we systemati- cally reviewed the recent progresses in the field of automated image-based protein subcellular location prediction, and clas- sified them into four categories including growing of bioim- age databases, description of subcellular location distribution patterns, classification methods, and applications of the pre- diction systems. Besides, we also discussed some potential directions in this field.
A new defect detection algorithm base on Support Vector Data Description (SVDD) is proposed. A fabric texture model is built on the gray-level histogram of textural fabric image. Two Gray-level Co-occurrence Matrix (G...
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In this study, a new fabric defect detection algorithm base on undecimated wavelet transform is proposed. The selection scheme of wavelet decomposition scales is investigated to set the decomposition scales adaptively...
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Several neutrosophic combination rules based on the Dempster-Shafer theory (DST) and Dezert-Smarandache theory (DSmT) are presented in this study. The new information fusing approaches proposed the neutrosophic belief...
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This study proposes a motion cue based pedestrian detection method with two-trame-filtering (Tff) for video surveillance. The novel motion cue is exploited by the gray value variation between two frames. Then Tff pr...
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This study proposes a motion cue based pedestrian detection method with two-trame-filtering (Tff) for video surveillance. The novel motion cue is exploited by the gray value variation between two frames. Then Tff processing filters the gradient magnitude image by the variation map. Summa- tions of the Tff gradient magnitudes in cells are applied to train a pre-deteetor to exclude most of the background regions. Histogram of Tff oriented gradient (HTffOG) feature is proposed for pedestrian detection. Experimental results show that this method is effective and suitable for real-time surveil- lance applications.
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