We theoretically and experimentally demonstrate a cylinder-shaped hole array with a small depth and an appropriate period integrated on a silicon-on-insulator substrate can enhance infrared absorption due to more bend...
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We theoretically and experimentally demonstrate a cylinder-shaped hole array with a small depth and an appropriate period integrated on a silicon-on-insulator substrate can enhance infrared absorption due to more bending of light and a higher back *** Si metal-semiconductor-metal(MSM)photodiode with an hole array,whose depth is 250 nm,exhibits a4-fold improved external quantum efficiency(EQE)of 81%,and an ultra-fast impulse response speed of 22 ps enabling a 3 d B bandwidth of up to 23.9 *** film with a thickness of 80 nm is integrated to broaden the response wavelength.A more than 500%EQE enhancement of the Si-based PbSe photodiode with 150-nm-deep photon-trapping holes is achieved at1550 nm compared to the device without hole structures.
A high sensitivity fiber optic temperature sensor based on Vernier effect in microwave photonic filter based on two paralleled F-P (Fabry-Perot) fiber ring is proposed and experimentally verified. Sensitivity is impro...
A high sensitivity fiber optic temperature sensor based on Vernier effect in microwave photonic filter based on two paralleled F-P (Fabry-Perot) fiber ring is proposed and experimentally verified. Sensitivity is improved through the Vernier effect, which is caused by two parallel F-P fiber rings with approximate lengths. Temperature interrogation is achieved by monitoring the notch frequency of the superimposed frequency response curve. The temperature sensitivity of -484.514kHz/℃ is achieved in experiment, which is 57 times of the sensor without Vernier effect. The improved sensitivity and simple structure make it have wide potential applications in temperature monitoring of power systems.
Traditional cancer treatments have disadvantages of large trauma area and toxic side effects while killing cancer ***-targeted sonodynamic therapy(SDT)can effectively improve specificity of cancer treatment and overco...
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Traditional cancer treatments have disadvantages of large trauma area and toxic side effects while killing cancer ***-targeted sonodynamic therapy(SDT)can effectively improve specificity of cancer treatment and overcome the problem of low tissue penetration depth caused by a photo-driven ***,we developed a porphyrin-based sonosensitizer with a water-soluble polymer as a biological carrier and a cRGD peptide for tumor targeting,which constituted a nano sonosensitizer(T-cRGD NPs)for fluorescence imaging-guided sonodynamic therapy.A comparable sonosensitizer(T-PEG NPs)without the targeting unit was also prepared for illustration of therapeutic *** to the role of peptide targeting,T-cRGD NPs can accumulate and enter tumor cells for fluorescence imaging and show a superior SDT effect than T-PEG NPs in *** imaging in vivo reveals that T-cRGD NPs can enrich in tumor tissues within 14 h with a good biocompatibility.
A crosstalk-free multichannel sensor based on a dual-Sagnac interferometer interrogated by microwave photonic filter (MPF) is demonstrated theoretically and experimentally in this paper. The dual-Sagnac interferometer...
A crosstalk-free multichannel sensor based on a dual-Sagnac interferometer interrogated by microwave photonic filter (MPF) is demonstrated theoretically and experimentally in this paper. The dual-Sagnac interferometer is taken as the sensing element as well as an optical spectrum slicer to implement a dual-passband MPF. Experimental results show that the proposed multichannel sensor is crosstalk-free, and the temperature sensitivity of each channel is -0.9884 MHz/℃ and -1.9302 MHz/℃, respectively. The sensing interrogation system has good linearity and stability and it is suitable for application scenarios where multiple points of temperature are required to monitor simultaneously.
In this paper, we propose and experimentally demonstrate a highly sensitive plasmonic nanohole metasurface sensor using nanoimprinting and electron beam evaporation. A refractive index sensitivity of 516 nm/RIU has be...
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The global antibiotic resistance crisis necessitates urgent *** innovative approach involves potentiating antibiotics and non-antibiotic drugs with adjuvants or boosters.A major drawback of these membrane-active boost...
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The global antibiotic resistance crisis necessitates urgent *** innovative approach involves potentiating antibiotics and non-antibiotic drugs with adjuvants or boosters.A major drawback of these membrane-active boosters is their limited biocompatibility,as they struggle to differentiate between prokaryotic and eukaryotic *** study reports the chemical biology investigation of a dual-action oligoamidine(OA1)booster with a glutathione-triggered decomposition ***1,when combined with other antimicrobial molecules,exhibits a triple-targeting mechanism including cell membrane disruption,DNA targeting,and intracellular enzyme *** multi-targeting mechanism not only enhances the in vitro and in vivo eradication of antibiotic-resistant“ESKAPE”pathogens,but also suppresses the development of bacterial ***,OA1 maintains its activity in bacterial cells by creating an oxidative environment,while it quickly decomposes in mammalian cells due to high glutathione *** mechanistic insights and design principles may provide a feasible approach to develop novel antimicrobial agents and effective anti-resistance combination therapies.
Although metal-based chemical agents have demonstrated promising bacteriostatic effects in phototherapy,their short excitation/emission wavelengths and inadequate phototherapy efficiencies make their application in vi...
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Although metal-based chemical agents have demonstrated promising bacteriostatic effects in phototherapy,their short excitation/emission wavelengths and inadequate phototherapy efficiencies make their application in vivo *** therefore synthesized a novel Pt(Ⅱ)metallacycle(Pt1110)that can be activated with a 980 nm laser for photodiagnosis/treatment in deep *** found that Pt1110 significantly improved photothermal conversion(95%improvement)and ^(1)O_(2) generation(ΦΔ75%increase)compared to the ligand itself 1 and was well capable of light-induced sterilization under safe laser irradiation(0.72 W/cm^(2)).In addition,Pt1110 has little to no toxicity to *** incorporated into liposome,Pt1110 NPs was effective in wound healing in infection and keratitis models upon laser irradiation,which was accurately observed by NIR-Ⅱfluorescence *** novel metal-coordinated supramolecular material has a potential to become a universal platform for phototherapy in deep tissue.
The self-energy corrections to phonons have mostly been observed for modes with zone-center (q=0) wave vectors. Here, we investigated the self-energy corrections to phonons in ionic-liquid-gated semiconductors, i.e., ...
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The self-energy corrections to phonons have mostly been observed for modes with zone-center (q=0) wave vectors. Here, we investigated the self-energy corrections to phonons in ionic-liquid-gated semiconductors, i.e., monolayer and bilayer WS2, experimentally. Apart from the previously observed A1g(Γ) mode renormalization by Raman spectroscopy, we additionally discovered that the zone-edge longitudinal acoustic (LA(M)) phonon also softened under finite electron doping. This observed renormalization effect arises from the LA(M) phonon-assisted electron scattering between the K and Q valleys in the conduction bands, indicating the nonadiabatic self-energy corrections dominate, different from the A1g(Γ) mode. The self-energy corrections of the two modes both depend on layer configurations. Our findings suggest that WS2 and other similar two-dimensional materials are intriguing playgrounds to study the electron-phonon interactions and valley-related physics.
The activation process of p-type doped GaAs0.5P0.5 (001) β2(2 × 4) reconstruction surface is investigated based on first principle calculations. For Cs-only adsorption, the adsorption energy rises as the Cs cove...
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Insulators are indispensable devices on power transmission lines. The self-shattering of insulators pose a threat to the operation of transmission lines. Insulators where self-shattering occurs are usually small objec...
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