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6th Conference on Frontiers in Optical Imaging and technology: Novel Technologies in Optical systems

作者： Zhu, Haixia Ni, Bo Feng, Zhenjie Qian, Yitong Zhou, Xiaoyan Ni, Haibin Yang, Lingsheng Chang, Jianhua Jiangsu Key Laboratory of Meteorological Observation and Information Processing School of Electronic and Information Engineering Nanjing University of Information Science and Technology Nanjing210044 China

ISBN: (数字)9781510679672

ISBN: (纸本)9781510679665

In this paper, an absorber based on split square graphene is designed, which produces double absorption peaks at different polarization incidence. The absorption rates of x-polarized waves at 7.86 THz and 12.63THz are 97.9% and 91.2% respectively. The absorption rates of y-polarized waves at 6.30 THz and 10.52 THz are 94.1% and 93.2%. In this paper, an absorber based on split square graphene is designed, which produces double absorption peaks at different polarization incidence. The absorption rates of x-polarized waves at 7.86 THz and 12.63THz are 97.9% and 91.2% respectively. The absorption rates of y-polarized waves at 6.30 THz and 10.52 THz are 94.1% and 93.2%. The effect of Fermi level on the dual polarization absorptivity of graphene is discussed. Therefore, this work may have great reference value for terahertz sensing, selective spectral detection and other fields. The effect of Fermi level on the dual polarization absorptivity of graphene is discussed. Therefore, this work may have great reference value for terahertz sensing, selective spectral detection and other fields. © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

关键词： Polarization

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Remote,selective,and in situ manipulation of liquid droplets on a femtosecond laser-structured superhydrophobic shape-memory polymer by near-infrared light

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science China Chemistry 2021年第5期64卷 861-872页

作者： Xue Bai Jiale Yong Chao Shan Yao Fang Xun Hou Feng Chen State Key Laboratory for Manufacturing System Engineering and Shaanxi Key Laboratory of Photonics Technology for Information School of Electronic Science and EngineeringXi’an Jiaotong UniversityXi’an 710049China

Droplet manipulation plays a significant role in the fields of biomedical detection,microfluidics,and chemical ***,it still remains a great challenge to simultaneously achieve remote,selective,and in situ droplet manipulation on the same ***,Fe_(3)O_(4)nanoparticles were doped in a shape-memory polymer(SMP)to prepare a photothermal-responsive Fe_(3)O_(4)-SMP composite which showed remarkable near-infrared(NIR)light-triggered shape-memory *** micropillar array was constructed on such Fe_(3)O_(4)-SMP composite through femtosecond laser microfabrication and fluoroalkylsilane *** surface wettability of the as-prepared surface can transform from a low-adhesive sliding state to a high-adhesive pinning state as the micropillars are deformed by ***,the deformed micropillars can stand up and restore to their original morphology under remote NIR light irradiation,resulting in the reversible and repeatable recovery of the ultralow-adhesive *** such light-triggered wettability switching,the droplets pinning on the sample surface can be remotely,selectively,and in situ ***,the superhydrophobic Fe_(3)O_(4)-SMP surface is successfully applied in lossless liquid transfer,selective droplet release,and droplet-based *** as-fabricated superhydrophobic surfaces with NIR light-controlled reversible wettability will hold great promise in the fields of liquid manipulation,lab-on-a-chip,and microfluidics.

关键词： droplet manipulation superhydrophobicity shape-memory polymer femtosecond laser light responsive

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Design and validation of a combined system for in situ measurement of photosensitizer fluorescence and tissue diffuse reflectance 14

Design and validation of a combined system for in situ measu...

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Optics in Health Care and Biomedical Optics XIV 2024

作者： Zhan, Huiqi Guo, Xingran Ke, Cheng Peng, Weijin Cui, Shengdong Huang, Zheng MOE Key Laboratory of Medical Optoelectronics Science and Technology Key Laboratory of Photonics Technology of Fujian Province School of Optoelectronics and Information Engineering Fujian Normal University Fuzhou China

ISBN: (纸本)9781510682122

Background: Quantitative measurement of photosensitizer during photodynamic therapy (PDT) is critical. One of the practical approaches is to measure photosensitizer’s fluorescence, however, the influence of tissue optic properties needs to be considered in in situ measurement. Objective: To design and validate a combined system for dual detection of fluorescence and tissue diffuse reflectance. Materials and Method:For fluorescence detection, a 405 nm laser was used for excitation, a power meter for monitoring laser power and a fiber optic spectrometer for recording fluorescence. For diffuse reflectance measurement, a halogen lamp was used as light source and a fiber optic spectrometer for recording diffuse reflectance. Hemoporfin (HMME) was used as a model photosensitizer. Mice were used to evaluate the dual detection function of fluorescence and tissue diffuse reflectance after i.v. injection of HMME. Results: Solutions of different concentrations of HMME were used to test the intensity responses of the fluorescence detection system. A linear correlation was observed at HMME concentration lower than 10 μg/ml. Dual-band correction using corresponding diffuse reflectance data was used for the correction of original fluorescence spectrum. Diffuse reflectance corrected fluorescence data might truly reflect HMME concentration in the skin tissue. Conclusion: The preliminary evaluation suggests that the combined system can be used for quantitative measurement of photosensitizer fluorescence. © 2024 SPIE.

关键词： Fluorescence Diffuse reflectance spectroscopy Tissues Photodynamic therapy Skin

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Dynamics and stability analysis of unbalance responses in mid-positioned electrically assisted turbocharger rotor

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International Journal of Mechanical system Dynamics 2024年第4期4卷 515-535页

作者： Mingyue Hu Shuqian Cao Xiaolin Cao Zhiyong Zhang Rixiu Men Zhenzhen You Tianyou Wang School of Mechanical Engineering Tianjin UniversityTianjinChina Tianjin Key Laboratory of Nonlinear Dynamics and Control TianjinChina National Key Laboratory of Vehicle Power System TianjinChina Science and Technology on Diesel Engine Turbocharging Laboratory China North Engine Research InstituteTianjinChina

Electrically assisted turbochargers(EAT)improve intake efficiency by motor-assisted compressor impeller rotation,enhancing the system's transient ***,the addition of motor rotor components has increased the number of unbalanced positions in the shaft system,leading to problems such as excessive compressor end vibration and complex changes in oil film *** evaluate the effects of unbalance in the motor rotor,along with the parameters of floating ring bearings(FRB),on the dynamic response of EAT,a finite element model of an EAT rotor supported by nonlinear FRB is developed,and the vibration response of the compressor end bearing is obtained by numerical *** results indicate:(1)In contrast to the effect of compressor and turbine unbalance,proper motor rotor unbalance is more effective in suppressing oil whirl instability in the high-speed operating ***,a new inner oil film whirl“instability interval”is also induced in the low-speed operating range,leading to an increase in the Y1 compressor-end amplitude at low and medium speeds,and this“instability interval”increases with the amount of unbalance.(2)When an oil whirl occurs in the oil film,the maximum eccentricity of the bearing surges and is greater than 0.3,which can be used as an effective threshold for determining whether the oil film is unstable in engineering applications.(3)A suitable outer oil-film clearance range should be 35–40μm,otherwise,a wide range of outer oil-film whirl instability *** the amount of unbalance and oil-film clearance to suppress the subsynchronous vibration of the EAT,provides a theoretical basis for the design of the dynamics of the nonlinear rotor bearing system and improves the stability of the turbocharger's operation.

关键词： electrically assisted turbocharger motor unbalance oil-film clearance rotor dynamics nonlinear vibration

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Effect of mouse skin autofluorescence on the measurement of photosensitizer fluorescence 14

Effect of mouse skin autofluorescence on the measurement of ...

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Optics in Health Care and Biomedical Optics XIV 2024

作者： Guo, Xingran Peng, Weijin Wei, Zhe Cui, Shengdong Zhan, Huiqi Ke, Cheng Huang, Zheng MOE Key Laboratory of Medical Optoelectronics Science and Technology Key Laboratory of Photonics Technology of Fujian Province School of Optoelectronics and Information Engineering Fujian Normal University Fuzhou China

ISBN: (纸本)9781510682122

Background: Mouse model is a unique tool for preclinical evaluation of photosensitizing drugs for their potential applications in photodynamic therapy (PDT). The fluorescent property of photosensitizer provides a useful means for in situ measurement of photosensitizer distribution. However, the autofluorescence of mouse tissues might potentially affect in situ photosensitizer fluorescence measurement. Objectives: The aim of this study was to evaluate the autofluorescence in lab mice and its influence on the in situ measurement of photosensitizer fluorescence. Materials and Materials and methods: ICR mice, commonly used lab animal model, were used. Mice were fed with regular diet and clean water. Domestically produced photosensitizing drug Hemoporfin® was used as a model sensitizer. Costume-built fluorescence imaging and spectroscope systems were used for fluorescence examination under the excitation wavelength of 400 ±5 nm, generated from a laser or LED panel. In situ fluorescence was examined before and after i.v. injection of Hemoporfin®. Results: Epifluorescence imaging examination showed yellowish and reddish autofluorescence fluorescence in the mouth, nose, paws and tail areas. The absorption and emission spectra of mouse tissue overlaid to some degrees with that of Hemoporfin®. In situ fluorescence examination of ICR mice showed significant influence of autofluorescence on the spectral and intensity measurement of Hemoporfin® fluorescence. Such influence might be eliminated by post-measurement spectral correction algorithms. Conclusions: The autofluorescence in mouse tissues poses a significant influence on the in situ measurement of fluorescence emission of Hemoporfin®. Careful post-measurement spectral correction is needed for accurately measuring photosensitizer fluorescence. © 2024 SPIE.

关键词： Tissue

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C1M2:a universal algorithm for 3D instance segmentation,annotation,and quantification of irregular cells

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science China(Life sciences) 2023年第10期66卷 2415-2428页

作者： Hao Zheng Songlin Huang Jing Zhang Ren Zhang Jialu Wang Jing Yuan Anan Li Xin Yang Zhihong Zhang Britton Chance Center and MOE Key Laboratory for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and TechnologyWuhan 430074China Key Laboratory of Biomedical Engineering of Hainan Province School of Biomedical EngineeringHainan UniversityHaikou 570228China School of Electronic Information and Communications Huazhong University of Science and TechnologyWuhan 430074China

Cell instance segmentation is a fundamental task for many biological applications,especially for packed cells in three-dimensional(3D)microscope images that can fully display cellular *** processing algorithms based on neural networks and feature engineering have enabled great progress in two-dimensional(2D)instance ***,current methods cannot achieve high segmentation accuracy for irregular cells in 3D *** this study,we introduce a universal,morphology-based 3D instance segmentation algorithm called Crop Once Merge Twice(C1M2),which can segment cells from a wide range of image types and does not require nucleus images.C1M2 can be extended to quantify the fluorescence intensity of fluorescent proteins and antibodies and automatically annotate their expression levels in individual *** results suggest that C1M2 can serve as a tissue cytometry for 3D histopathological assays by quantifying fluorescence intensity with spatial localization and morphological information.

关键词： 3D instance segmentation irregular cells fluorescence images neural networks fluorescence intensity tissue cytometry

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Fabrication of a 3D bioprinting model for posterior capsule opacification using GelMA and PLMA hydrogel-coated resin

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Regenerative Biomaterials 2024年第4期3卷 52-65页

作者： Xin Liu Jiale Li Shuyu Liu Yan Long Ching Kang Chen Zhao Ling Wei Shaoqi Huang Yi Luo Bo Dai Xiangjia Zhu Cataract and Lens Refractive Surgery Group Department of OphthalmologyEye&ENT Hospital of Fudan UniversityShanghai 200031People’s Republic of China NHC Key Laboratory of Myopia Key Laboratory of MyopiaChinese Academy of Medical SciencesFudan UniversityShanghai 200031People’s Republic of China Shanghai Key Laboratory of Visual Impairment and Restoration Shanghai 200031People’s Republic of China Engineering Research Center of Optical Instrument and System the Ministry of EducationShanghai Key Laboratory of Modern Optical SystemUniversity of Shanghai for Science and TechnologyShanghai 200093China

Posterior capsule opacification(PCO)remains the predominant complication following cataract surgery,significantly impairing visual function *** this study,we developed a PCO model that closely mimics the anatomical structure of the crystalline lens capsule *** model incorporated a threaded structure for accurate positioning and observation,allowing for opening and *** 3D printing technology,a stable external support system was created using resin material consisting of a rigid,hollow base and *** replicate the lens capsule structure,a thin hydrogel coating was applied to the resin *** biocompatibility and impact on cellular functionality of various hydrogel compositions were assessed through an array of staining techniques,including calcein-AM/PI staining,rhodamine staining,BODIPY-C11 staining and EdU staining in conjunction with transwell ***,the PCO model was utilized to investigate the effects of eight drugs with anti-inflammatory and anti-proliferative properties,including 5-aminoimidazole-4-carboxamide ribonucleotide(AICAR),THZ1,sorbinil,4-octyl itaconate(4-OI),xanthohumol,zebularine,rapamycin and caffeic acid phenethyl ester,on human lens epithelial cells(HLECs).Confocal microscopy facilitated comprehensive imaging of the PCO *** results demonstrated that the GelMA 605%þPLMA 2%composite hydrogel exhibited superior biocompatibility and minimal lipid peroxidation levels among the tested ***,compared to using hydrogel as the material for 3D printing the entire model,applying surface hydrogel spin coating with parameters of 2000 rpm�2 on the resin-based 3D printed base yielded a more uniform cell distribution and reduced ***,rapamycin,4-OI and AICAR demonstrated potent antiproliferative effects in the drug intervention *** microscopy imaging revealed a uniform distribution of HLECs along the anatomical structure of the crystalline lens capsule with

关键词： posterior capsule opacification(PCO) human lens epithelial cells(HLECs) 3D bioprinting hydrogel resin

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Deep Learning for Covert Communication

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China Communications 2024年第9期21卷 40-59页

作者： Shen Weiguo Chen Jiepeng Zheng Shilian Zhang Luxin Pei Zhangbin Lu Weidang Yang Xiaoniu Innovation Studio of Academician Yang National Key Laboratory of Electromagnetic Space SecurityJiaxing 314033China College of Information Engineering Zhejiang University of TechnologyHangzhou 310023China School of Information Science and Technology Fudan UniversityShanghai 200438China

In recent years,deep learning has been gradually used in communication physical layer receivers and has achieved excellent *** this paper,we employ deep learning to establish covert communication systems,enabling the transmission of signals through high-power signals present in the prevailing environment while maintaining covertness,and propose a convolutional neural network(CNN)based model for covert communication receivers,namely Deep *** model leverages CNN to execute the signal separation and recovery tasks commonly performed by traditional *** enables the direct recovery of covert information from the received *** simulation results show that the proposed Deep CCR exhibits significant advantages in bit error rate(BER)compared to traditional receivers in the face of noise and multipath *** verify the covert performance of the covert method proposed in this paper using the maximum-minimum eigenvalue ratio-based method and the frequency domain entropy-based *** results indicate that this method has excellent covert *** also evaluate the mutual influence between covert signals and opportunity signals,indicating that using opportunity signals as cover can cause certain performance losses to covert *** the interference-tosignal power ratio(ISR)is large,the impact of covert signals on opportunity signals is minimal.

关键词： convolutional neural network covert communication deep learning

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Fine-Grained Source Code Vulnerability Detection via Graph Neural Networks 35

Fine-Grained Source Code Vulnerability Detection via Graph N...

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35th International Conference on Software engineering and Knowledge engineering, SEKE 2023

作者： Wang, Jingjing Huang, Minhuan Nie, Yuanpin Kuang, Xiaohui Li, Xiang Zhong, Wenjing National Key Laboratory of Science and Technology Information System Security Beijing China Xidian University Xi’an China

Although the number of exploitable vulnerabilities in software continues to increase, the speed of bug fixes and software updates have not increased accordingly. It is therefore crucial to analyze the source code and identify vulnerabilities in the early phase of software development. However, vulnerability location in most of the current machine learning-based methods tends to concentrate at the function level. It undoubtedly imposes a burden on further manual code audits when faced with large-scale source code projects. In this paper, a fine-grained source code vulnerability detection model based on Graph Neural Networks (GNNs) is proposed with the aim of locating vulnerabilities at the function level and line level. Our empirical evaluation on different C/C++ datasets demonstrated that our proposed model outperforms the state-of-the-art methods and achieves significant improvements even when faced with more complex, real-project source code. © 2023 Knowledge systems Institute Graduate School. All rights reserved.

关键词： Graph neural networks

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A fast calculation method for three-impulse contingency return trajectory during the near-moon phase based on differential algebra

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Chinese Journal of Aeronautics 2025年第4期38卷 286-304页

作者： Lin LU Haiyang LI Tianshan DONG Wanmeng ZHOU College of Aerospace Science and Technology National University of Defense TechnologyChangsha 410073China Hunan Key Laboratory of Intelligent Planning and Simulation for Aerospace Missions Changsha 410073China Beijing Institute of Spacecraft System Engineering Beijing 100094China China Astronaut Research and Training Center Beijing 100094China

Aimed at the demand of contingency return at any time during the near-moon phase in the manned lunar landing missions,a fast calculation method for three-impulse contingency return trajectories is ***,a three-impulse contingency return trajectory scheme is presented by combining the Lambert transfer and maneuver at the special ***,a calculation model of three-impulse contingency return trajectories is ***,fast calculation methods are proposed by adopting the high-order Taylor expansion of differential algebra in the twobody trajectory dynamics model and perturbed trajectory dynamics ***,the performance of the proposed methods is verified by numerical *** results indicate that the fast calculation method of two-body trajectory has higher calculation efficiency compared to the semi-analytical calculation method under a certain accuracy *** to its high efficiency,the characteristics of the three-impulse contingency return trajectories under different contingency scenarios are further analyzed *** findings can be used for the design of contingency return trajectories in future manned lunar landing missions.

关键词： Manned lunar landing Contingency return trajectory Trajectory calculation method Differential algebra Trajectory characteristic analysis

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