检索结果-内蒙古大学图书馆

High-efficiency Fe(III)-doped ultrathin VO_(2)nanobelts boosted peroxydisulfate activation for actual antibiotics photodegradation

引用

Chinese Chemical Letters 2025年第3期36卷 199-205页

作者： Shukun Le Peng Wang Yuhao Liu Mutao Xu Quansheng Liu Qijie Jin Jie Miao Chengzhang Zhu Haitao Xu Inner Mongolia Key Laboratory of High-Value Functional Utilization of Low Rank Carbon Resources Chemical Engineering CollegeInner Mongolia University of TechnologyHohhot 010050China School of Environmental Science and Engineering Nanjing Tech UniversityNanjing 210009China Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science MOEQingdao University of Science and TechnologyQingdao 266042China

It has been challenging for Fe(III)regeneration in Fe-based photocatalysts for continuous peroxydisulfate(PDS)activation due to the lower ability to reduce Fe(III).In this work,Fe-doped ultrathin VO_(2)(Fe-VO_(2))nanobelts were synthesized for purifying metronidazole(MNZ)via PDS *** an efficient Fentonlike catalyst for PDS activation,2 wt%Fe-doped VO_(2)can remove 98%of MNZ within 40 min and exhibits impressive *** synergistic effect of Fe-VO_(2)and Fe(III)activated PDS boosted the photocatalytic ***,SO_(4)•^(−),h+,O_(2)•^(−),^(1)O_(2),and•OH were the main reactive *** effects of initial MNZ concentration,Fe-VO_(2),PDS dosage,and various anions/cations on MNZ removal by the Fe-VO_(2)/PDS/Vis system were *** intermediates of MNZ degradation and possible pathways were determined by density function theory(DFT)calculations and *** study provided a sustainable technology using Fe-doped ultrathin VO_(2)nanobelts for photocatalytic PDS activation and decontamination of pharmaceutical wastewater.

关键词： Fe-doped VO_(2)nanobelts Photodegradation Persulfate activation Antibiotics removal Bimetallic cycle

来源：评论

学校读者我要写书评

暂无评论

The plant retromer components SNXs bind to ATG8 and CLASP to mediate autophagosome movement along microtubules

引用

Molecular Plant 2025年第3期18卷 416-436页

作者： Yanglan Liao Xibao Li Wenlong Ma Xinyi Lin Jiayi Kuang Xuanang Zheng Zien Li Fanfan Qiao Chuanliang Liu Jun Zhou Faqiang Li Ruixi Li Byung-Ho Kang Hongbo Li Caiji Gao Guangdong Provincial Key Laboratory of Biotechnology for Plant Development School of Life SciencesMOE Key Laboratory&Guangdong Provincial Key Laboratory of Laser Life ScienceCollege of BiophotonicsSouth China Normal UniversityGuangzhou 510631China Centre for Cell&Developmental Biology and State Key Laboratory of Agrobiotechnology School of Life SciencesChinese University of Hong KongHong KongChina College of Life Sciences South China Agricultural UniversityGuangzhou 510642China Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes School of Life SciencesInstitute of Plant and Food ScienceSouthern University of Science and TechnologyShenzhen 518055China

In eukaryotic cells,autophagosomes are double-membrane vesicles that are highly mobile and traffic along cytoskeletal *** core autophagy-related proteins(ATGs)and other regulators involved in autophagosome biogenesis in plants have been extensively studied,the specific components regulating plant autophagosome motility remain *** this study,using TurboID-based proximity labeling,we identify the retromer subcomplex comprising sorting nexin 1(SNX1),SNX2a,and SNX2b as interacting partners of ***,SNX proteins decorate ATG8-labeled autophagosomes and facilitate their coordinated movement along *** of SNX proteins restricts the motility of autophagosomes in the cytoplasm,resulting in decreased autophagic ***,we show that the microtubule-associated protein CLASP is a bridge,connecting the SNX-ATG8-decorated autophagosomes to the ***,the clasp-1 mutant phenotype resembles that of plants with disrupted SNXs or microtubule networks,displaying diminished autophagosome motility and reduced autophagic ***,our study unveils a hitherto unanticipated role of the SNXs subcomplex in connecting autophagosomes with microtubules to promote autophagosome mobility in Arabidopsis.

关键词： autophagy SNX CLASP microtubule autophagosome trafficking Arabidopsis thaliana

来源：评论

学校读者我要写书评

暂无评论

Quantitative fs-laser crystalline lens softening surgery towards presbyopia treatment based on optical coherence elastography

引用

Biomedical Optics Express 2025年第5期16卷 2171-2183页

作者： Zhang, Zhuoyu Lv, Haijun Zhang, Hao Zhang, Ying Wang, Bingxi Liao, Yinan Zhou, Zimeng Deng, Jun Bian, Ruonan Chen, Shangbin Quan, Tingwei Liu, Xiuli Wang, Honghao Wang, Jing Li, Peng Lv, Xiaohua Zeng, Shaoqun Britton Chance Center for Biomedical Photonics MOE Key Laboratory for Biomedical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Hubei Wuhan430074 China Department of Biomedical Engineering College of Life Science and Technology Huazhong University of Science and Technology Hubei Wuhan430074 China State Key Lab of Modern Optical Instrumentation College of Optical Science and Engineering Zhejiang University Zhejiang Hangzhou310027 China

Presbyopia, a prevalent age-related vision disorder, is primarily characterized by the progressive loss of accommodative ability due to crystalline lens hardening, as described by the Helmholtz theory of accommodation. Among emerging presbyopia correction techniques, femtosecond laser lentotomy (fs-lento) has gained attention for its potential to restore accommodative function through the creation of intracapsular gliding planes via laser-induced optical breakdown (LIOB). This approach offers distinct advantages, including potential accommodative recovery, a non-invasive nature, minimal tissue disruption, and negligible bleeding risk. However, despite two decades of technical development, the clinical translation of fs-lento remains hindered by challenges in quality control and outcome heterogeneity, primarily due to the absence of precise quantitative methods for assessing the surgical effects on tissue mechanical properties. To address these limitations, we developed a femtosecond laser ocular research apparatus (FLORA) system for surgical investigations. Furthermore, we implemented a novel PZT-contact optical coherence elastography (OCE) system, modified from SD-OCT and validated through phantom experiments, for quantitative tissue mechanical characterization. Our experimental results using ex vivo porcine lenses demonstrated that the sequential creation of 16 flower-patterned gliding planes (2 × 3 mm2) with pulse energy of 4.1 µJ, generating cavitation bubbles © 2025 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement.

关键词： Femtosecond lasers

来源：评论

学校读者我要写书评

暂无评论

P2Y_(14)R activation facilitates liver regeneration via CREB/DNMT3b/Dact-2/β-Catenin signals in acute liver failure

引用

Acta Pharmaceutica Sinica B 2025年第2期15卷 919-933页

作者： Mengze Zhou Yehong Li Jialong Qian Xinli Dong Yanshuo Guo Li Yin Chunxiao Liu Kun Hao Qinghua Hu State Key Laboratory of Natural Medicines School of PharmacyChina Pharmaceutical UniversityNanjing211198China School of Life Science and Technology China Pharmaceutical UniversityNanjing 211198China

Acute liver failure(ALF)is lack of broadly approved therapeutic strategy except liver *** a glycogen metabolic intermediate,UDP-glucose(UDP-G)has been considered to accelerate liver ***,the role of UDP-G and its receptor P2Y purinoceptor 14(P2Y_(14)R)in ALF remains *** present study aims to investigate the role and underlying mechanisms of UDP-G/P2Y_(14)R axis in *** this study,hepatic P2Y_(14)R is significantly increased in TAA-induced and partial hepatectomy-induced ALF,while knockout of whole-body P2Y_(14)R aggravates liver failure,manifested by inhibitingβ-Catenin-mediated liver ***,P2Y_(14)R deficiency exhibits impaired liver regeneration in mice suffer partial ***,only hepatocellular specific deletion of P2Y_(14)R(P2Y_(14)R^(flox/flox)Alb^(cre/+))mice shows a similar phenomenon,rather than stellate cell specific deletion of P2Y_(14)R(P2Y_(14)R^(flox/flox)Lrat^(cre/+))***,P2Y_(14)R induction regulates methylation of Dact-2 through CREB/DNMT3b signals in hepatocytes,subsequently inhibiting the expression of Dact-2 which is a stabilizer ofβ-Catenin degradation complex,leading to the activation ofβ-Catenin-mediated liver ***,the administration of exogenous UDP-G can accelerate liver regeneration and liver function recovery after partial hepatectomy in hepatocellular carcinoma ***,the findings propose an unrecognized role of P2Y_(14)R in ALF and provide an effective adjuvant strategy for treatment of ALF.

关键词： Acute liver failure UDP-Glucose P2Y_(14)R Liver regeneration Hepatocyte Partial hepatectomy b-Catenin Dact-2

来源：评论

学校读者我要写书评

暂无评论

Non-Hermitian Physics in Mesoscopic Electron Transport Through Coupled Quantum Dots

引用

Chinese Physics Letters 2025年第4期42卷 114-124页

作者： Yiyang Li Jincheng Lu Chen Wang Jian-Hua Jiang School of Physical Science and Technology&Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow UniversitySuzhou215006China Key Laboratory of Intelligent Optoelectronic Devices and Chips of Jiangsu Higher Education Institutions School of Physical Science and TechnologySuzhou University of Science and TechnologySuzhou215009China Advanced Technology Research Institute of Taihu Photon Center School of Physical Science and TechnologySuzhou University of Science and TechnologySuzhou 215009China Department of Physics Zhejiang Normal UniversityJinhua321004China School of Biomedical Engineering Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei230026China Suzhou Institute for Advanced Research University of Science and Technology of ChinaSuzhou215123China School of Physical Sciences University of Science and Technology of ChinaHefei 230026China

We investigate electron mesoscopic transport in a three-terminal setup with coupled quantum dots and a magnetic *** mapping the original transport problem into a non-Hermitian Hamiltonian form,we study the interplay between the coherent couplings between quantum dots,the magnetic flux,and the dissipation due to the tunnel coupling with the reservoirs.

关键词： quantum dots magnetic fluxby electron mesoscopic transport non hermitian physics magnetic fluxand coherent couplings transport problem tunnel coupling

来源：评论

学校读者我要写书评

暂无评论

TRIM66-HP1γ remodels the chromatin through phase separation

引用

Biophysics Reports 2025年第1期11卷 18-33页

作者： Siyuan Shen Feng Chen Yifan Zhang Fudong Li Xuebiao Yao Dan Liu Yunyu Shi Liang Zhang Center for Advanced Interdisciplinary Science and Biomedicine of IHM Division of Life Sciences and MedicineUniversity of Science and Technology of China Ministry of Education Key Laboratory for Membraneless Organelles and Cellular Dynamics University of Science and Technology of China Hefei National Research Center for Cross disciplinary Science University of Science and Technology of China

Chromatin contains not only heterochromatin(HC) and euchromatins(EC) but also facultative heterochromatin(f HC), which experience the dynamic remodeling between HCs and ECs by different regulators. The regulation of f HCs involves lots of different cell functions, like genomic stability and gene transcription. Heterochromatin protein 1(HP1) recognizes methylated H3K9 and reshapes the chromatin into the f HCs through liquid–liquid phase separation(LLPS). Among the three members of the HP1 family, HP1α can condensate by itself and HP1β forms granules with the help of TRIM28, while the HP1γ cannot phase separation alone either and the coordinator is still unclear. So, in this study, we investigated the molecular mechanism of how HP1γ interacts with TRIM66 through Px Vx L motif. Based on that, we examined the key regions that controlled the TRIM66-HP1γ co-phase separation behaviors both in vitro and in vivo. Furthermore, we proved that the liquid granules of TRIM66-HP1γ and chromatin highly correlated with H3K9me3 sites, which indicated the relationship with DNA damage response. Finally, combined with our previous study, we proposed the system for how TRIM66 remodeled the chromatin into compressed f HC through the TRIM66-HP1γ-H3K9me3 axis with liquid–liquid phase separation.

关键词： Chromatin TRIM66-HP1γ Facultative heterochromatin Phase separation

来源：评论

学校读者我要写书评

暂无评论

Bifunctional iron-porphyrin metal-organic frameworks for organic photoelectrochemical transistor gating and biosensing

引用

Chinese Chemical Letters 2025年第3期36卷 227-231页

作者： Cheng-Shuang Wang Bing-Yu Zhou Yi-Feng Wang Cheng Yuan Bo-Han Kou Wei-Wei Zhao Jing-Juan Xu State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China School of Materials Science and Engineering Yancheng Institute of TechnologyYancheng 224051China

Iron-porphyrin metal-organic frameworks(MOFs)have emerged as a remarkable class of semiconductors with adjustable photoelectrical properties and peroxidase-mimicking activities,yet their full potential remains largely *** organic photoelectrochemical transistor(OPECT)has been proven to be a prominent platform for diverse ***,iron-porphyrin MOFs,as bifunctional photo-gating module and horseradish peroxidase-mimicking nanozyme,is explored for novel OPECT *** by alpha-fetoprotein(AFP)-dependent sandwich immunorecognition and therein glucose oxidase(GOx)-generated H_(2)O_(2)to etch CdS quantum dots on the surface of iron-porphyrin MOFs,this OPECT bioanalysis achieved high-performance AFP detection with a low detection limit of 24 fg/*** work featured a bifunctional iron-porphyrin MOFs gated OPECT,which is envisioned to inspire more interest in developing the diverse MOFs-nanozymes toward novel optoelectronics and beyond.

关键词： Organic photoelectrochemical transistor Iron-porphyrin metal-organic frameworks Nanozymes Peroxidase-mimicking activity Biosensing

来源：评论

学校读者我要写书评

暂无评论

Synthetic Cu(Ⅲ)from copper plating wastewater for onsite decomplexation of Cu(Ⅱ)-and Ni(Ⅱ)-organic complexes

引用

Chinese Chemical Letters 2025年第2期36卷 470-475页

作者： Junyi Yu Yin Cheng Anhong Cai Xianfeng Huang Qingrui Zhang National and Local Joint Engineering Research Center for Ecological Treatment Technology of Urban Water Pollution College of Life and Environmental ScienceWenzhou UniversityWenzhou 325035China State Key Laboratory of Metastable Materials Science and Technology Hebei Key Laboratory of Heavy Metal Deep-Remediation in Water and Resource ReuseSchool of Environmental and Chemical EngineeringYanshan UniversityQinhuangdao 066004China

Herein,the Cu(Ⅲ)synthesized from copper plating effluent was developed for the first time to evaluate the onsite degradation performance of heavy metal complexes in the wastewater,thus achieving the purpose of“treating waste with waste”.The results indicated that synthetic Cu(Ⅲ)presented the excellent decomplexation performance for Cu(Ⅱ)/Ni(Ⅱ)-organic *** removal efficiency of Cu(Ⅱ)/Ni(Ⅱ)-EDTA significantly increased with increasing Cu(Ⅲ)dosage,and the degradation of Cu(Ⅱ)/Ni(Ⅱ)-EDTA by synthetic Cu(Ⅲ)system displayed highly p H-dependent *** radical quencher experiments confirmed that Cu(Ⅲ)direct oxidation were mainly involved in the degradation of Cu(Ⅱ)-***,the continuous decarboxylation process was proven to be the main degradation pathway of Cu(Ⅱ)-EDTA in Cu(Ⅲ)*** coexisting substances(SO42-,Cl-and fulvic acids)showed little impacts at low level for the removal of Cu(Ⅱ)/Ni(Ⅱ)-EDTA,while retarded the degradation of Cu(Ⅱ)-EDTA slightly at high level,which features high selective ***,it was also effective to remove Cu(Ⅱ)/Ni(Ⅱ)-EDTA from in treating actual Cu/Ni-containing wastewater through synthetic Cu(Ⅲ)treatment.

关键词： Copper plating wastewater Cu(III) Decomplexation Treating waste with waste Selectivity

来源：评论

学校读者我要写书评

暂无评论

Stepwise activated probe for cell surface glycan imaging

引用

science China Chemistry 2025年

作者： Chunyi Zhang Jing Chen Xiaoyao Bai Shengnan Fu Xin Su State Key Laboratory of Organic-Inorganic Composites Beijing Key Laboratory of Bioprocess Beijing Advanced Innovation Center for Soft Matter Science and Engineering College of Life Science and Technology Beijing University of Chemical Technology

Fluorescent DNA probes commonly used for in situ imaging of cell surface glycans are “always-on” probes(AOPs), which produce high background noise and lack spatial specificity. Molecular dynamics simulations indicate that single-stranded DNA(ssDNA) can stably associate with the cell membrane, contributing to persistent background signals in AOPs. To overcome this challenge, a stepwise activated probe(SAP) is developed for in situ imaging of cell surface glycans. In SAP, the cell surface glycan is labeled by rolling circle amplification product through metabolic glycan labeling strategies. The product hybridizes a fluorophore and quencher-labeled ssDNA reporter to form a double strand producing primary enhancement of fluorescence signal. Nicking enzyme(***) cleaves the double strand and releases the quencher, further enhancing the signal. Nonspecific absorption of the reporter on the cellular membrane does not increase the fluorophore-quencher distance in SAP or trigger *** cleavage. As a result, only the glycan sites are illuminated. SAP not only exhibits high imaging specificity but also greatly simplifies the imaging procedure by reducing the washing steps. SAP offers a considerable improvement in detection specificity and sensitivity by employing a two-step activation and amplification process, making it a powerful method for in situ fluorescence imaging.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Luteolin,a common flavone in vegetables,acts as a hormetin possessing neurotrophic function:signaling mediated by inducing mitochondrial stress

引用

Food science and Human Wellness 2025年第2期14卷 569-580页

作者： Alex Xiong Gao Tracy Chenxi Xia Maggie Suisui Guo Gary Kawing Yuen Kevin Qiyun Wu Tina Tingxia Dong Karl Wah-Keung Tsim Division of Life Science and Center for Chinese Medicine The Hong Kong University of Science and TechnologyHong Kong 999077China Shenzhen Key Laboratory of Edible and Medicinal Bioresources HKUST Shenzhen Research InstituteShenzhen 518000China

This study aims to uncover the hormetic process of luteolin,a common dietary flavone,in neuronal cells through its role in inducing mitochondrial *** rat pheochromocytoma PC12 cells,luteolin at low concentrations caused a mild and reversible loss of mitochondrial membrane potential(MMP),while high concentrations of luteolin triggered intense and sustained depolarization of *** MMP disturbance was shown to have a close association with the trophic and/or toxic effects triggered by luteolin;because the common mitochondrial uncouplers shared similar bi-phase dose-response on cell viability,as that of *** with the induced MMP pertubation,luteolin triggered the development of autophagy and mitophagy,as determined by m Cherry-GFP-LC3B tandem protein,and by the co-localization of mitochondrial/lysosomal *** application of autophagy inhibitors in the cultures blocked the luteolin-induced neurotrophic activities and sensitized the cells to be less resistant to luteolin-mediated *** flavonoids also displayed similar properties in the cultures,indicating that these compounds act as hormetic pharmacological inducers that stimulate cells to become more resilient and adapt to *** study provides a unifying mechanistic explanation for the neuro-beneficial effects of luteolin and other flavonoids.

关键词： Flavonoids Hormesis Mitochondrial membrane potential Autophagy Mitophagy

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：