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Non-Hermitian Physics in Mesoscopic Electron Transport Through Coupled Quantum Dots

Chinese Physics Letters 2025年第4期42卷 114-124页

作者： Yiyang Li Jincheng Lu Chen Wang Jian-Hua Jiang School of Physical Science and Technology&Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow UniversitySuzhou215006China Key Laboratory of Intelligent Optoelectronic Devices and Chips of Jiangsu Higher Education Institutions School of Physical Science and TechnologySuzhou University of Science and TechnologySuzhou215009China Advanced Technology Research Institute of Taihu Photon Center School of Physical Science and TechnologySuzhou University of Science and TechnologySuzhou 215009China Department of Physics Zhejiang Normal UniversityJinhua321004China School of Biomedical Engineering Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei230026China Suzhou Institute for Advanced Research University of Science and Technology of ChinaSuzhou215123China School of Physical Sciences University of Science and Technology of ChinaHefei 230026China

We investigate electron mesoscopic transport in a three-terminal setup with coupled quantum dots and a magnetic *** mapping the original transport problem into a non-Hermitian Hamiltonian form,we study the interplay between the coherent couplings between quantum dots,the magnetic flux,and the dissipation due to the tunnel coupling with the reservoirs.

关键词： quantum dots magnetic fluxby electron mesoscopic transport non hermitian physics magnetic fluxand coherent couplings transport problem tunnel coupling

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TRIM66-HP1γ remodels the chromatin through phase separation

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Biophysics Reports 2025年第1期11卷 18-33页

作者： Siyuan Shen Feng Chen Yifan Zhang Fudong Li Xuebiao Yao Dan Liu Yunyu Shi Liang Zhang Center for Advanced Interdisciplinary Science and Biomedicine of IHM Division of Life Sciences and MedicineUniversity of Science and Technology of China Ministry of Education Key Laboratory for Membraneless Organelles and Cellular Dynamics University of Science and Technology of China Hefei National Research Center for Cross disciplinary Science University of Science and Technology of China

Chromatin contains not only heterochromatin(HC) and euchromatins(EC) but also facultative heterochromatin(f HC), which experience the dynamic remodeling between HCs and ECs by different regulators. The regulation of f HCs involves lots of different cell functions, like genomic stability and gene transcription. Heterochromatin protein 1(HP1) recognizes methylated H3K9 and reshapes the chromatin into the f HCs through liquid–liquid phase separation(LLPS). Among the three members of the HP1 family, HP1α can condensate by itself and HP1β forms granules with the help of TRIM28, while the HP1γ cannot phase separation alone either and the coordinator is still unclear. So, in this study, we investigated the molecular mechanism of how HP1γ interacts with TRIM66 through Px Vx L motif. Based on that, we examined the key regions that controlled the TRIM66-HP1γ co-phase separation behaviors both in vitro and in vivo. Furthermore, we proved that the liquid granules of TRIM66-HP1γ and chromatin highly correlated with H3K9me3 sites, which indicated the relationship with DNA damage response. Finally, combined with our previous study, we proposed the system for how TRIM66 remodeled the chromatin into compressed f HC through the TRIM66-HP1γ-H3K9me3 axis with liquid–liquid phase separation.

关键词： Chromatin TRIM66-HP1γ Facultative heterochromatin Phase separation

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Enhanced Visible Light Photocatalytic Activity of BiOCl with Ti_(3)C_(2) Nanosheets for Pollutant Photodegradation

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Journal of Wuhan University of technology(Materials science) 2025年第3期40卷 650-659页

作者： ZHENG Jingyan DENG Yichao XU Mengying LI Lian TREMBLAY Pier-Luc ZHANG Tian School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China Sanya Science and Education Innovation Park Wuhan University of TechnologySanya 572024China Shaoxing Institute for Advanced Research Wuhan University of TechnologyShaoxing 312300China State Key Laboratory of Silicate Materials for Architectures Wuhan University of TechnologyWuhan 430070China School of Chemistry Chemical Engineeringand Life ScienceWuhan University of TechnologyWuhan 430070China

Ti_(3)C_(2)/BiOCl composite was successfully synthesized by combining BiOCl(BOC)with an exposed(110)crystal plane and Ti_(3)C_(2) using a simple hydrothermal *** photocatalytic performance of produced composite was evaluated using the degradation of rhodamine B(RhB)and tetracycline hydrochloride(TCH)under visible *** results demonstrated that Ti_(3)C_(2)/BOC composite had higher photocatalytic activity than pure *** optimum incorporation amount of Ti_(3)C_(2) was 2 wt%.The photodegradation rate of 2 wt%-Ti_(3)C_(2)/BOC at 10 min to 20 mg/L RhB was 97.6%,which was much higher than that of BOC(75.3%).Similarly,the photodegradation rate of 2 wt%-Ti_(3)C_(2)/BOC to 10 mg/L TCH at 30 min was 80.4%,which was higher than BOC(68.1%).In addition,the prepared 2 wt%-Ti_(3)C_(2)/BOC composite also maintained good stability even after four *** impedance spectroscopy(EIS),transient photocurrent response(IT)and ultraviolet-visible diffuse reflectance spectroscopy(UV-vis)confirmed that the photoelectrochemical properties of 2 wt%-Ti_(3)C_(2)/BOC composite were significantly *** the basis of analyzing the action mechanism of photocatalyst,it was pointed out that·O_(2)^(-)and h~+were the main active substances in the photodegradation of RhB and TCH by 2 wt%-Ti_(3)C_(2)/BOC.

关键词： Ti_(3)C_(2)/BiOCl photodegradation rhodamine B tetracycline hydrochloride

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Real-time identification of multiple nanoclusters with a protein nanopore in single-cluster level

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Nano Research 2024年第1期17卷 262-269页

作者： Ling Zhang Peilei He Huang Chen Qingda Liu Libo Li Xun Wang Jinghong Li Department of Chemistry Center for BioAnalytical ChemistryKey Laboratory of Bioorganic Phosphorus Chemistry&Chemical BiologyTsinghua UniversityBeijing 100084China School of Chemistry and Chemical Engineering Guangdong Prov Key Lab Green Chem Prod TechnolSouth China University of TechnologyGuangzhou 510640China New Cornerstone Science Laboratory Shenzhen 518054China Beijing Institute of Life Science and Technology Beijing 102206China Center for BioAnalytical Chemistry Hefei National Laboratory of Physical Science at MicroscaleUniversity of Science and Technology of ChinaHefei 230026China

It is important and challenging to analyze nanocluster structure with atomic ***,α-hemolysin nanopore was used to identify nanoclusters at the single molecule level by providing two-dimensional(2D)dwell time–current blockage spectra and translocation event frequency which sensitively depended on their *** such as Anderson,Keggin,Dawson,and a few lacunary Dawson polyoxometalates with very similar structures,even with only a two-atom difference,could be *** nanopore device could simultaneously measure multiple nanoclusters in a mixture qualitatively and ***,molecular dynamics(MD)simulations provided microscopic understandings of the nanocluster translocation dynamics and yielded 2D dwell time–current blockage spectra in close agreement with *** nanopore platform provides a novel powerful tool for nanocluster characterization.

关键词： nanopore single-molecule nanocluster polyoxometalates real-time detection

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Sex-Specific and State-Dependent Neuromodulation Regulates Male and Female Locomotion and Sexual Behaviors

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Research 2024年第4期2024卷 343-347页

作者： Xinyu Jiang Mengshi Sun Jie Chen Yufeng Pan The Key Laboratory of Developmental Genes and Human Disease School of Life Science and TechnologySoutheast UniversityNanjing 210096China Co-innovation Center of Neuroregeneration Nantong UniversityNantong 226019China

Males and females display dimorphic behaviors that often involve sex-specific locomotor *** the sexually dimorphic locomotion is mediated is poorly *** this study,we identify a neuropeptide that oppositely regulates locomotion for efficient sexual behaviors in Drosophila males and *** find that males are less active than females if ***,when sexually aroused through activating homologous but sexually dimorphic pC1 neurons,males exhibit higher activity levels than *** discover diuretic hormone 44(DH44)that functions in pC1 neurons in a sex-specific way to inhibit male locomotion and promote female ***,DH44 exerts opposite effects in sexually aroused flies to promote male locomotion and suppress female locomotion,which is crucial for successful male courtship and female *** findings demonstrate sexually dimorphic and state-dependent control of locomotor activity by pC1 neuronal activity and DH44 modulation.

关键词： opposite motion Female

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Stereoselective metabolic disruption of cypermethrin by remolding gut homeostasis in rat

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Journal of Environmental sciences 2023年第4期126卷 761-771页

作者： Quan Zhang Sijia Gu YanWang Shitao Hu Siqing Yue Cui Wang Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province College of EnvironmentZhejiang University of TechnologyHangzhou 310032China School of Life Science Zhejiang Chinese Medical UniversityHangzhou 310053China

Cypermethrin(CYP), a prototypical synthetic pyrethroid, reportedly causes metabolic disruption, while its stereoselective impact remains elusive. This study initially revealed that only α-CYP caused significant weight loss at 8.5 mg/(kg·day) in rats. All three CYP isomers caused the accumulation of hepatic glycogen, and hyperlipemia phenotype as the increment of total triglyceride. Rats treated with α-CYP had markedly high blood glucose levels and homeostasis model assessment of insulin resistance index. The systematic inflammation of θ-CYP group rats was evidenced by high lipopolysaccharide-binding protein levels and abnormalities of leukocytes indices. By examining the gut microbiome, we found thatα-CYP-treated rats had low contents of Firmicutes and high levels of Verrucomicrobia while Elusimicrobia was enriched in the β-CYP group. The increasing alpha diversity in the θ-CYP group may be due to the dominance of pathogenic bacteria and the increase of probiotics to counteract adverse effects. Exclusively, the α-CYP group enriched total short-chain fatty acids(SCFAs), whereas most SCFAs depleted in the θ-CYP group. The correlation analysis further found Firmicutes, an energy storage modulator, was positive to body weight(BW),while SCFAs exerted the opposite, confirming the low BW in α-CYP. Blood glucose that correlated well with SCFAs and Verrucomicrobia can be accounted for the discrepancy betweenα-CYP and θ-CYP. Overall, the three isomers exerted stereoselective glycolipid disruption in rats, and gut homeostasis acted as vital indicators.

关键词： Cypermethrin Stereoisomeric selectivity Gut microbiota Short-chain fatty acids Glycolipid metabolism

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Design and Analysis of Liquid-Filled Pipeline Inspection Robot 15

Design and Analysis of Liquid-Filled Pipeline Inspection Rob...

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15th IEEE Global Reliability and Prognostics and Health Management Conference, PHM-Beijing 2024

作者： Wang, Tianhua He, Zichun Yang, Dingxin Bai, Guanghan Tao, Junyong College of Intelligence Science and Technology National University of Defense Technology Changsha China National Key Laboratory of Equipment State Sensing and Smart Support College of Intelligence Science and Technology Changsha China

ISBN: (纸本)9798350354010

With the rapid development of manufacturing industry, the prognostics and health management (PHM) of pipeline transportation plays a vital role in different industries and our daily life. Improving the reliability of pipeline transportation through traditional means such as manual checks and long-term fixed-point observation is difficult. In this paper, we provide a robot tailored for internal inspection within liquid-filled pipelines, addressing the current engineering issues concerning the safety of pipeline usage. The robot can be remotely operated through a control cabinet, cable retracting device, and armored optical cable to inspect specific conditions inside liquid-filled pipeline. It is characterized by its ability to minimize personal injury, assess the operational status of the pipeline, and offer a cost-effective solution. This paper focuses on the total schematic design of the robot and the structural and mechanics performance analysis. Then, a prototype robot for liquid-filled pipeline inspection is built up. Ultimately, the performance of the prototype robot is validated through a series of tests, including pipeline passability, pressure resistance, and navigation speed in water. The results indicate that the robot's performance meets the design requirements, which can enhance the accuracy of PHM and reliability of pipeline transportation. © 2024 IEEE.

关键词： Inspection

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In situ growth of phosphorized ZIF-67-derived amorphous CoP/Cu_(2)O@CF electrocatalyst for efficient hydrogen evolution reaction

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Frontiers of Chemical science and Engineering 2023年第10期17卷 1430-1439页

作者： Ruiwen Qi Xiao Liu Hongkai Bu Xueqing Niu Xiaoyang Ji Junwei Ma Hongtao Gao Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Sciences MOECollege of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China

Transition metal phosphides have been extensively studied for catalytic applications in water ***,we report an in situ phosphorization of zeolitic imidazole frameworks(ZIF-67)to generate amorphous cobalt phosphide/ZIF-67 heterojunction on a self-supporting copper foam(CF)substrate with excellent performance for hydrogen evolution reaction(HER).The needleleaf like copper hydroxide was anchored on CF surface,which acted as implantation to grow *** intermediate product was phosphorized to obtain final electrocatalyst(CoP/Cu_(2)O@CF)with uniform particle size,exhibiting a rhombic dodecahedron structure with wrinkles on the *** electrochemical measurement proved that CoP/Cu_(2)O@CF catalyst exhibited excellent HER activity and long-term stability in 1.0 mol·L^(–1)KOH *** overpotential was only 62 mV with the Tafel slope of 83 mV·dec^(–1)at a current density of 10 mA·cm^(–2),with a large electrochemical active surface *** also showed competitive performance at large current which indicated the potential application to industrial water electrolysis to produce ***-principle calculations illustrated that benefit from the construction of CoP/ZIF-67 heterojunction,the d-band center of CoP downshifted after bonding with ZIF-67 and the Gibbs free energy(ΔGH*)changed from–0.18 to–0.11 eV,confirming both decrease in overpotential and excellent HER *** work illustrates the efficient HER activity of CoP/Cu_(2)O@CF catalyst,which will act as a potential candidate for precious metal electrocatalysts.

关键词： CoP/Cu_(2)O@CF electrocatalyst phosphorization HER DFT

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Study on Simulation Method to Determine the Inflation Threshold of Head Protective Airbag for High-speed Helicopter Pilot 2

Study on Simulation Method to Determine the Inflation Thresh...

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2022 2nd International Conference on Mechanical, Aerospace, and Automotive Engineering, CMAAE 2022

作者： Feng, Zhijie Fan, Chengcheng Ke, Chuanyi Zhang, Haibo Liu, Tao AVIC Aerospace Life-Support Industries LTD. Xiangyang441000 China Aviation Key Laboratory of Science and Technology on Life-Support Technology Xiangyang441000 China School of Aerospace Engineering Tsinghua University Beijing100084 China

Compared with ordinary helicopters, the flying speed of high-speed helicopters is increased from 350km / h to 450km / h, and the crash speed is bound to exceed 12.8m / s, which greatly increases the probability of collision injury of the pilots' head. The equipment, such as the traditional safety belts and crashworthy seats, cannot play an effective role in protection. In order to effectively improve the crashworthy survival rate of high-speed helicopter pilots, the main method in European and American countries is to design additional head protective airbags. The paper carried out the study on the simulation method for determining the high-speed helicopter head protection airbag inflation threshold value. Based on LS-DYNA, it has established the impact simulation model of the high-speed helicopter cockpit - seat - safety belt - pilot system. At the same time, the HIC value of the dummy head (no more than 1000N) and the pull force of the shoulder strap (no more than 8890N) are taken as the objective function to simulate the collision process of the man/seat system in multiple states of the high-speed helicopter. Finally, the inflation threshold of the head protective airbag is determined, which provides a critical support for the development of the head protective airbag. © Published under licence by IOP Publishing Ltd.

关键词： Helicopters

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Bifunctional iron-porphyrin metal-organic frameworks for organic photoelectrochemical transistor gating and biosensing

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Chinese Chemical Letters 2025年第3期36卷 227-231页

作者： Cheng-Shuang Wang Bing-Yu Zhou Yi-Feng Wang Cheng Yuan Bo-Han Kou Wei-Wei Zhao Jing-Juan Xu State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China School of Materials Science and Engineering Yancheng Institute of TechnologyYancheng 224051China

Iron-porphyrin metal-organic frameworks(MOFs)have emerged as a remarkable class of semiconductors with adjustable photoelectrical properties and peroxidase-mimicking activities,yet their full potential remains largely *** organic photoelectrochemical transistor(OPECT)has been proven to be a prominent platform for diverse ***,iron-porphyrin MOFs,as bifunctional photo-gating module and horseradish peroxidase-mimicking nanozyme,is explored for novel OPECT *** by alpha-fetoprotein(AFP)-dependent sandwich immunorecognition and therein glucose oxidase(GOx)-generated H_(2)O_(2)to etch CdS quantum dots on the surface of iron-porphyrin MOFs,this OPECT bioanalysis achieved high-performance AFP detection with a low detection limit of 24 fg/*** work featured a bifunctional iron-porphyrin MOFs gated OPECT,which is envisioned to inspire more interest in developing the diverse MOFs-nanozymes toward novel optoelectronics and beyond.

关键词： Organic photoelectrochemical transistor Iron-porphyrin metal-organic frameworks Nanozymes Peroxidase-mimicking activity Biosensing

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