检索结果-内蒙古大学图书馆

Long-term changes in radial growth of seven tree species in the mixed broadleaf-Korean pine forest in Northeast China:Are deciduous trees favored by climate change?

引用

Journal of Forestry Research 2024年第5期35卷 63-77页

作者： Xiufang Gong Danyang Yuan Liangjun Zhu Zongshan Li Xiaochun Wang National Engineering Laboratory for Applied Technology of Forestry and Ecology in South China College of Life Science and TechnologyCentral South University of Forestry and TechnologyChangsha 410004People’s Republic of China Center for Ecological Research and Key Laboratory of Sustainable Forest Ecosystem Management-Ministry of Education School of ForestryNortheast Forestry UniversityHarbin 150040People’s Republic of China State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085People’s Republic of China

The role of the temperate mixed broadleaf-Korean pine forest(BKF)in global biogeochemical cycles will depend on how the tree species community responds to climate;however,species-specific responses and vulner-abilities of common trees in BKF to extreme climates are poorly *** we used dendrochronological meth-ods to assess radial growth of seven main tree species(Pinus koraiensis,Picea jezoensis,Abies nephrolepis,Fraxinus mandshurica,Phellodendron amurense,Quercus mongolica,and Ulmus davidiana)in an old-growth BKF in response to climate changes in the Xiaoxing’an Mountains and to improve predictions of changes in the tree species *** in most months and winter precipita-tion significantly negatively affected growth of *** and ***,but positively impacted growth of *** and the broadleaf species,especially ***-rica and *** and relative humidity in June significantly positively impacted the growth of most tree *** positive effect of the temperature during the previous non-growing season(PNG)on growth of *** and *** strengthened significantly with rapid warming around 1981,while the impact of PNG temperature on the growth of *** and *** changed from significantly negative to weakly negative or positive at this *** negative response of radial growth of *** and *** to precipitation during the growing season gradually weakened,and the negative response to PNG precipitation was *** the studied species,*** was the most resistant to drought,and *** recovered the best after extreme *** davidiana,*** and *** were more resistant to extreme cold than the other *** warming generally exacerbated the opposite growth patterns of conifer(decline)and broadleaf(increase)*** broadleaf tree species in the old-growth BKF probably will gradually become dominan

关键词： Tree rings Extreme climate Resistance and recovery Broad-leaved and Korean pine mixed forest

来源：评论

学校读者我要写书评

暂无评论

Lignin derived absorbent for efficient and sustainable CO_(2) capture

引用

Chinese Journal of Chemical Engineering 2023年第2期54卷 89-97页

作者： Yuandong Cui Bin He Yu Lei Yu Liang Wanting Zhao Jian Sun Xiaomin Liu School of Chemistry and Chemical Engineering Qingdao UniversityQingdao 266071China School of Life Science Beijing Institute of TechnologyBeijing 100081China Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information TechnologyBeijing Engineering Research Center of Cellulose and Its DerivativesAdvanced Research Institute of Multidisciplinary ScienceBeijing Institute of TechnologyBeijing 100081China

High and cost-efficient capture of CO_(2) is a prerequisite and an inevitable path of carbon emission reduction. To address the challenges(high cost, low efficiency, less sustainability, etc.) of existing petroleum-based CO_(2) absorbents, herein, a class of efficient and sustainable lignin-based absorbents were resoundingly prepared by grafting the active amine group on a lignin derived compound vanillin and alkali lignin. The results demonstrated that vanillin modified by acrylamide achieved the excellent absorption capacity among the three absorbents, whose ability was 0.114 g CO_(2) per gram of absorbent under 25 ℃ and 100 kPa. In addition, the absorbent retained stable absorbability of CO_(2) after 6 *** absorbing capacity of the absorbent formed by the coupling of vanillin and acrylamide to CO_(2) was much greater than their own(i.e. 0 g CO_(2) ·g^(-1)vanillin, 0.01 g CO_(2) ·g^(-1) acrylamide, respectively).Detailed information revealed the multi-site synergistic absorption mechanism, in which CO_(2) has C and O double interactions with the amide group of the absorbent, and single interaction with the hydroxyl oxygen on the benzene ring of the absorbent. The absorption capacity of modified lignin for CO_(2) is as high as 0.12 g CO_(2) per gram of absorbent, which is comparable with that of model compound *** work not only provides a new idea for the design of bio-absorbents for CO_(2) capture, but explores the application potential of lignin-based materials.

关键词： Lignin(model compound) CO_(2)absorption Amide group Multi-site Acid-base Hydrogen bonding

来源：评论

学校读者我要写书评

暂无评论

Cytochrome P450 Enzyme Design by Constraining the Catalytic Pocket in a Diffusion Model

引用

Research 2025年第1期2024卷 618-630页

作者： Qian Wang Xiaonan Liu Hejian Zhang Huanyu Chu Chao Shi Lei Zhang Jie Bai Pi Liu Jing Li Xiaoxi Zhu Yuwan Liu Zhangxin Chen Rong Huang Hong Chang Tian Liu Zhenzhan Chang Jian Cheng Huifeng Jiang Key Laboratory of Engineering Biology for Low-Carbon Manufacturing Tianjin Institute of Industrial BiotechnologyChinese Academy of SciencesTianjin 300308China University of Chinese Academy of Sciences Beijing 100049China National Center of Technology Innovation for Synthetic Biology Tianjin 300308China College of Biotechnology Tianjin University of Science and TechnologyTianjin 300457China Department of Biochemistry and Biophysics School of Basic Medical SciencesPeking UniversityBeijing 100191China College of Life Science and Technology Wuhan Polytechnic UniversityWuhanHubei 430023China State Key Laboratory of Elemento-Organic Chemistry College of ChemistryNankai UniversityTianjin 300071China College of Life Science Nankai UniversityTianjin 300071China

Although cytochrome P450 enzymes are the most versatile biocatalysts in nature,there is insufficient comprehension of the molecular mechanism underlying their functional innovation ***,by combining ancestral sequence reconstruction,reverse mutation assay,and progressive forward accumulation,we identified 5 founder residues in the catalytic pocket of flavone 6-hydroxylase(F6H)and proposed a"3-point fixation"model to elucidate the functional innovation mechanisms of P450s in *** to this design principle of catalytic pocket,we further developed a de novo diffusion model(P450Diffusion)to generate artificial ***,among the 17 non-natural P450s we generated,10 designs exhibited significant F6H activity and 6 exhibited a 1.3-to 3.5-fold increase in catalytic capacity compared to the natural *** work not only explores the design principle of catalytic pockets of P450s,but also provides an insight into the artificial design of P450 enzymes with desired functions.

关键词： cytochrome P progressive forward accumulationwe cytochrome p enzymes molecular mechanism ancestral sequence reconstructionreverse mutation assayand de novo design catalytic pocket functional innovation

来源：评论

学校读者我要写书评

暂无评论

Enzymes in Nanomedicine for Anti-tumor Therapy

引用

Chemical Research in Chinese Universities 2023年第1期39卷 72-82页

作者： ZHOU Tong YUAN Shuaiqi QIAN Pinrong WU Yuzhou Hubei Engineering Research Center for Biomaterials and Medical Protective Materials Hubei Key Laboratory of Bioinorganic Chemistry&Materia MedicaKey Laboratory of Material Chemistry for Energy Conversion and StorageMinistry of EducationSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan430074P.R.China College of Life Science and Technology Huazhong University of Science and TechnologyWuhan430074P.R.China

Natural enzymes are biological macromolecules catalyzing reactions in living organisms and regulating biological *** delivery of enzymes into tumor tissues for anti-tumor therapy through nanotechnology has attracted emerging interest in recent *** this paper,we systematically summarize the latest research progress on enzymes that used for anti-tumor therapy in nanomedicine with different action mechanisms,including anti-tumor principles,delivery modes,response modes,and synergistic therapeutic design of these ***,we discuss the challenges and future prospects of enzymes for anti-tumor nanomedicine.

关键词： Enzyme Nanomedicine Protein delivery Cancer therapy

来源：评论

学校读者我要写书评

暂无评论

A β-cyclodextrin covalent organic framework used as a chiral stationary phase for chiral separation in gas chromatography

引用

Chinese Chemical Letters 2022年第2期33卷 898-902页

作者： Bo Tang Wei Wang Huipeng Hou Yiquan Liu Zongkun Liu Lina Geng Liquan Sun Aiqin Luo Key Laboratory of Molecular Medicine and Biotherapy School of Life ScienceBeijing Institute of TechnologyBeijing 100081China

Chiral covalent organic frameworks(CCOFs) featuring chirality, stability, and good porosity have attracted a considerable amount of attention due to their important applications, such as asymmetric catalysis, chiral separation, and chiral recognition. In this study, a β-cyclodextrin(β-CD) covalent organic framework(β-CD-COF) diluted with polysiloxane OV-1701 was explored as a novel chiral stationary phase(CSP) for gas chromatography(GC) separation of racemates. The β-CD-COF coated capillary column had excellent selectivity, not only for the separation of linear alkanes, linear alcohols, fatty acid methyl esters mixture, the Grob mixture and positional isomers, but also for the resolution of chiral compounds, including chiral alcohols, aldehydes, ethers, and amino acid derivatives. In addition, the β-CD-COF-coated capillary column presented good repeatability and reproducibility. This work indicated the great potential of the CCOFs coated capillary column for the chromatographic separation of enantiomers.

关键词： β-Cyclodextrin Covalent organic framework Chiral stationary phase Gas chromatography Enantioseparation

来源：评论

学校读者我要写书评

暂无评论

A hybrid piecewise FDD strategy for refrigeration charge fault of airborne vapor-compression cycle system

引用

INTERNATIONAL JOURNAL OF REFRIGERATION 2022年 135卷 164-173页

作者： Sun, Chengbin Wang, Hexu Jiang, Yanlong Gao, Zanjun Wang, Ju [a]Key Laboratory of Aircraft Environment Control and Life Support MIIT Nanjing University of Aeronautics and Astronautics 29 Yudao St. Nanjing 210016 China [b]Aviation Key Laboratory of Science and Technology on Aero Electromechanical System Integration Nanjing 211106 China

Many researchers have carried out study on refrigerant charge fault for variable refrigerant flow (VRF) airconditioning system, while few pay attention to refrigerant charge fault for vapor-compression refrigerant cycle system (VCS) of enhanced vapor injection (EVI) with a flash tank onboard. To develop a strategy for refrigerant charge fault of the above system, the optimization methods have been implemented to predict the refrigerant charge level (RCL) based on virtual refrigerant charge (VRC) models. Firstly, Pearson correlation coefficient analysis is employed to obtain the characteristic parameters. Secondly, a piecewise modified VRC model with the different characteristic parameters from VRC models is obtained for two cases of RCL < 75% and RCL > 75%. Meanwhile, combined with the principal component analysis (PCA) and the support vector machine (SVM) algorithm, a PCA-SVM model is developed to improve the prediction accuracy, and the average root mean squared error (RMSE) is only 7.8 compared to 14.9 of the modified VRC model when RCL > 75%, meanwhile, the correctly detected ratio is improved from 62.8% to 84.5%. Then, for solving the difficulty of fault detection and diagnosis (FDD) when RCL > 160%, the moving time window average (MA) algorithm is introduced and an online PCA-MA-SVM model is developed. Finally, a hybrid piecewise FDD strategy combined with three models for refrigeration charge fault in airborne VCS of EVI with a flash tank is obtained.

关键词： Vapor-compression refrigeration cycle system Enhanced vapor injection Refrigerant charge fault support vector machine Moving time window average

来源：评论

学校读者我要写书评

暂无评论

RACK1A promotes hypocotyl elongation by scaffolding light signaling components in Arabidopsis

引用

Journal of Integrative Plant Biology 2024年第5期66卷 956-972页

作者： Yajuan Fu Wei Zhu Yeling Zhou Yujing Su Zhiyong Li Dayan Zhang Dong Zhang Jinyu Shen Jiansheng Liang Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes Department of BiologySchool of Life SciencesInstitute of Plant and Food SciencesSouthern University of Science and TechnologyShenzhen 518055China

Plants deploy versatile scaffold proteins to intricately modulate complex cell *** these,RACK1A(Receptors for Activated C Kinase 1A)stands out as a multifaceted scaffold protein functioning as a central integrative hub for diverse signaling ***,the precise mechanisms by which RACK1A orchestrates signal transduction to optimize seedling development remain largely ***,we demonstrate that RACK1A facilitates hypocotyl elongation by functioning as a flexible platform that connects multiple key components of light signaling ***1A interacts with PHYTOCHROME INTERACTING FACTOR(PIF)3,enhances PIF3 binding to the promoter of BBX11 and down-regulates its ***,RACK1A associates with ELONGATED HYPOCOTYL 5(HY5)to repress HY5 biochemical activity toward target genes,ultimately contributing to hypocotyl *** darkness,RACK1A is targeted by CONSTITUTIVELY PHOTOMORPHOGENIC(COP)1 upon phosphorylation and subjected to COP1-mediated degradation via the 26 S proteasome *** findings provide new insights into how plants utilize scaffold proteins to regulate hypocotyl elongation,ensuring proper skoto-and photo-morphogenic development.

关键词： Arabidopsis hypocotyl development light signaling components RACK1 scaffoldprotein

来源：评论

学校读者我要写书评

暂无评论

Two sex pheromone receptors for sexual communication in the American cockroach

引用

science China(life sciences) 2024年第7期67卷 1455-1467页

作者： Na Li Renke Dong Huanchao Zeng Yan Zhang Run Huang Wei Liu Fengming Cao Jincong Yu Mingtao Liao Jingyou Chen Wenlei Zhang Zejian Huang Jiahui Wang Li Li Shen Zhu Danyan Huang Zining Li Xiaoshuai Zhang Dongwei Yuan Nan Chen Yongliang Fan Guirong Wang Coby Schal Yufeng Pan Sheng Li Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology Institute of Insect Science and TechnologySchool of Life SciencesSouth China Normal UniversityGuangzhou 510631China Guangmeiyuan R&D Center Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied TechnologySouth China Normal UniversityMeizhou 514589China Lingnan Guangdong Laboratory of Modern Agriculture Genome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518000China State Key Laboratory of Crop Stress Biology for Arid Areas and Key Laboratory of Integrated Pest Management on the Loess Plateau of Ministry of AgricultureNorthwest A&F UniversityYangling 712100China Department of Entomology and Plant Pathology North Carolina State UniversityRaleigh 27695USA The Key Laboratory of Developmental Genes and Human Disease School of Life Science and TechnologySoutheast UniversityNanjing 210096China

Volatile sex pheromones are vital for sexual communication between males and *** of the American cockroach,Periplaneta americana,produce and emit two sex pheromone components,periplanone-A(PA)and periplanone-B(PB).Although PB is the major sex attractant and can attract males,how it interacts with PA in regulating sexual behaviors is still *** this study,we found that in male cockroaches,PA counteracted PB *** identified two odorant receptors(ORs),OR53 and OR100,as PB/PA and PA receptors,***53 and OR100 were predominantly expressed in the antennae of sexually mature males,and their expression levels were regulated by the sex differentiation pathway and nutrition-responsive *** localization of OR53 and OR100 in male antennae further revealed that two types of sensilla coordinate a complex two-pheromone-two-receptor pathway in regulating cockroach sexual *** findings indicate distinct functions of the two sex pheromone components,identify their receptors and possible regulatory mechanisms underlying the male-specific and age-dependent sexual behaviors,and can guide novel strategies for pest management.

关键词： sex pheromone odorant receptor sexual attraction sex differentiation cockroach

来源：评论

学校读者我要写书评

暂无评论

Polystyrene nanoplastics induce glycolipid metabolism disorder via NF-κB and MAPK signaling pathway in mice

引用

Journal of Environmental sciences 2024年第3期137卷 553-566页

作者： Xingpei Fan Xiaoyan Li Jiaxin Li Yuxia Zhang Xiangjuan Wei Hailong Hu Boya Zhang Haining Du Meimei Zhao Ruijiao Zhu Daqian Yang Yuri Oh Ning Gu School of Life Science and Technology Harbin Institute of TechnologyHarbin 150001China State Key Laboratory of Urban Water Resource and Environment Harbin Institute of TechnologyHarbin 150006China Department of Medicine Renal Electrolyte and Hypertension DivisionDepartment of GeneticsPerelman School of MedicineUniversity of PennsylvaniaPhiladelphia 19104USA Faculty of Education Wakayama UniversityWakayama 640-8441Japan

Nanoplastics-induced developmental and reproductive toxicity,neurotoxicity and immunotoxicity are a focus of widespread ***,the effects of nanoplastics(NPs)on glycolipid metabolism and the precise underlying mechanisms are unclear at ***,we showed that oral administration of polystyrene nanoparticles(PS-NPs)disrupts glycolipid metabolism,with reactive oxygen species(ROS)identified as a potential key signaling *** PS-NPs treatment,excessive production of ROS induced the infammatory response and activated the antioxidant pathway through nuclear factor-erythroid factor 2-related factor *** activation of nuclear factor-κB(NFκB)signaling pathway induced the phosphorylation of the mitogen-activated protein kinases(MAPK)signaling pathway,which induced the activation of extracellular regulated kinases(ERK)and *** activation of the MAPK signaling proteins induced high continued phosphorylation of insulin receptor substrate-1,in turn,leading to decreased protein kinase B(Akt)activity,which weakened the sensitivity of liver cells to insulin signals and induced insulin *** parallel,phosphorylation of Akt led to loss of control of Fo XO1,a key gene of gluconeogenesis,activating transcription of glucose-6-phosphatase(G6PC)and phosphoenolpyruvate carboxykinase(PEPCK)in a manner dependent on PGC1α.Moreover,the activated ERK promoted lipid accumulation through ERK-PPARγ***,sterol regulatory element-binding protein-1 and levels of its downstream lipogenic enzymes,ACC-1,were *** treatment with the antioxidant resveratrol,PS-NPs-induced glucose and lipid metabolic disorders were improved by inhibiting ROS-induced activation of NFκB and MAPK signaling pathway in *** on above,PS-NPs exposure disrupts glycolipid metabolism in mice,with ROS identified as a potential key signaling molecule.

关键词： Nanoplastics Resveratrol Hyperglycemia Lipid metabolism Infammatory response Reactive oxygen species(ROS)

来源：评论

学校读者我要写书评

暂无评论

Effect of purine diet on prognosis of deep brain stimulation for Parkinson's disease

引用

Food science and Human Wellness 2025年第3期14卷 1026-1033页

作者： Bowen Chang Yuge Jiang Chuanxing Feng Bowen Li Jiaming Mei Chaoshi Niu Department of Neurosurgery The First Affi liated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China Key Laboratory of Xin’an Medicine Ministry of EducationAnhui Provincial Key Laboratory of R&D of Chinese MedicineAnhui University of Chinese MedicineHefei 230038China Center for Food Nutrition and Functional Food Engineering School of Food Science and TechnologyJiangnan UniversityWuxi 214122China

Uric acid(UA)is a naturally antioxidant that is strongly associated with the development and progression of Parkinson's disease(PD).The purine diet is an important exogenous pathway that modulates blood UA *** brain stimulation(DBS)is an important tool for PD *** study aimed to explore the effects of preoperative purine diet on the prognosis of patients with PD after ***-four patients with PD who underwent DBS were included in this study,and their clinical data,blood UA levels,and daily purine *** were followed up for improvement 1 year after *** found that patient higher purine intake was strongly associated with the rate of improvement after DBS and was a protective factor for patient *** purine intake from meat and seafood was significantly higher in the responsive patients than in the lessresponsive *** analysis showed that UA mediated 78%of the effect of purine intake on motor symptom improvement after *** summary,we observed that purine intake is strongly associated with the rate of improvement in motor symptoms after subthalamic nucleus-DBS in patients with *** study provides a reference for preoperative diet planning in patients with PD undergoing DBS.

关键词： Purine diet Nutrition Parkinson’s disease Deep brain stimulation Brain connectivity

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：