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检索条件"机构=Key Laboratory of Science and Technology on Life-support Technology"
11898 条 记 录,以下是71-80 订阅
排序:
Cytochrome P450 Enzyme Design by Constraining the Catalytic Pocket in a Diffusion Model
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Research 2025年 第1期2024卷 618-630页
作者: Qian Wang Xiaonan Liu Hejian Zhang Huanyu Chu Chao Shi Lei Zhang Jie Bai Pi Liu Jing Li Xiaoxi Zhu Yuwan Liu Zhangxin Chen Rong Huang Hong Chang Tian Liu Zhenzhan Chang Jian Cheng Huifeng Jiang Key Laboratory of Engineering Biology for Low-Carbon Manufacturing Tianjin Institute of Industrial BiotechnologyChinese Academy of SciencesTianjin 300308China University of Chinese Academy of Sciences Beijing 100049China National Center of Technology Innovation for Synthetic Biology Tianjin 300308China College of Biotechnology Tianjin University of Science and TechnologyTianjin 300457China Department of Biochemistry and Biophysics School of Basic Medical SciencesPeking UniversityBeijing 100191China College of Life Science and Technology Wuhan Polytechnic UniversityWuhanHubei 430023China State Key Laboratory of Elemento-Organic Chemistry College of ChemistryNankai UniversityTianjin 300071China College of Life Science Nankai UniversityTianjin 300071China
Although cytochrome P450 enzymes are the most versatile biocatalysts in nature,there is insufficient comprehension of the molecular mechanism underlying their functional innovation ***,by combining ancestral sequence ... 详细信息
来源: 评论
Effect of purine diet on prognosis of deep brain stimulation for Parkinson's disease
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Food science and Human Wellness 2025年 第3期14卷 1026-1033页
作者: Bowen Chang Yuge Jiang Chuanxing Feng Bowen Li Jiaming Mei Chaoshi Niu Department of Neurosurgery The First Affi liated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China Key Laboratory of Xin’an Medicine Ministry of EducationAnhui Provincial Key Laboratory of R&D of Chinese MedicineAnhui University of Chinese MedicineHefei 230038China Center for Food Nutrition and Functional Food Engineering School of Food Science and TechnologyJiangnan UniversityWuxi 214122China
Uric acid(UA)is a naturally antioxidant that is strongly associated with the development and progression of Parkinson's disease(PD).The purine diet is an important exogenous pathway that modulates blood UA *** bra... 详细信息
来源: 评论
Single‑Neuron Reconstruction of the Macaque Primary Motor Cortex Reveals the Diversity of Neuronal Morphology
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Neuroscience Bulletin 2025年 第3期41卷 525-530页
作者: Siyu Li Yan Shen Yefei Chen Zexuan Hong Lewei Zhang Lufeng Ding Chao‑Yu Yang Xiaoyang Qi Quqing Shen Yanyang Xiao Pak‑Ming Lau Zhonghua Lu Fang Xu Guo‑Qiang Bi CAS Key Laboratory of Brain Function and Disease Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230026China Interdisciplinary Center for Brain Information Shenzhen-Hong Kong Institute of Brain ScienceShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Shenzhen Technological Research Center for Primate Translational Medicine Shenzhen Key Laboratory for Molecular Biology of Neural DevelopmentShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China The Key Laboratory of Biomedical Imaging Science and System Chinese Academy of SciencesShenzhen 518055China CAS Key Laboratory of Brain Connectome and Manipulation the Brain Cognition and Brain Disease InstituteShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Faculty of Life and Health Sciences Shenzhen University of Advanced TechnologyShenzhen 518107China
Dear Editor,The primary motor cortex,also known as MOp in rodents,F1,or M1 in primates[1],plays a crucial role in autonomous motor *** is interconnected with other motor control structures such as the basal ganglia,th... 详细信息
来源: 评论
Proteomic analysis of B cells in peripheral lymphatic system reveals the dynamics during the systemic lupus erythematosus progression
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Biophysics Reports 2025年 第2期11卷 129-142页
作者: Liming Sun Yuanyuan Yin Yuqing Cao Chunlei Chen Yutong Guo Zeming Cai Jiarui Wu Qingrun Li Key Laboratory of Systems Health Science of Zhejiang Province School of Life Science Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences School of Life Science and Technology ShanghaiTech university CAS Key Laboratory of Systems Biology Shanghai Institute of Biochemistry and Cell Biology Center for Excellence in Molecular Cell Science Chinese Academy of Sciences University of Chinese Academy of Sciences
In this study, we conducted a comprehensive proteomic analysis of B cells from the spleen, mesenteric lymph nodes(mLN), and peripheral blood mononuclear cells(PBMC) in a time-course model of systemic lupus erythematos... 详细信息
来源: 评论
SnS/WSe van der Waals Single-Detector Spectrometer With a Dynamically Selecting Spectral Reconstruction Strategy
IEEE Electron Device Letters
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IEEE Electron Device Letters 2025年 第5期46卷 801-804页
作者: Zhou, Yang Mu, Haoran Zhang, Congwen Xu, Renjing Zhang, Guangyu Lin, Shenghuang Songshan Lake Materials Laboratory Dongguan523808 China South China Normal University Moe Key Laboratory of Laser Life Science Guangdong Provincial Key Laboratory of Laser Life Science Guangzhou Key Laboratory of Spectral Analysis and Functional Probes College of Biophotonics Guangzhou510631 China The Hong Kong University of Science and Technology Microelectronics Thrust Guangzhou511442 China Institute of Physics Chinese Academy of Science Beijing100190 China
The single-detector spectrometers based on 2D layer van der Waals (vdW) heterojunctions offer advantages in spectral reconstruction due to their high sensitivity, tunable optical properties, and the ability to cover a... 详细信息
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The role of PilU in the surface behaviors of Pseudomonas aeruginosa
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mlife 2025年 第1期4卷 83-95页
作者: Jingchao Zhang Yan Luo Yiwu Zong Shangping Lu Yi Shi Fan Jin Kun Zhao Center for Medical Genetics Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of ChinaChengduChina Key Laboratory of SystemsBioengineering(Ministry of Education) School of Chemical Engineering and TechnologyFrontiers Science Center for Synthetic BiologyTianjin UniversityTianjinChina Guangzhou General Institute of Medical Research GuangzhouChina School of Life Science and Technology University of Electronic Science and Technology of ChinaChengduChina The Sichuan Provincial Key Laboratory for Human Disease Gene Study The Institute of Laboratory MedicineSichuan Provincial People's HospitalUniversityof Electronic Science and Technology of ChinaChengduChina CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic BiologyShenzhenInstitutes of Advanced TechnologyChinese Academy of SciencesShenzhenChina Institute of Fundamental and Frontier Sciences University of Electronic Science andTechnology of ChinaChengduChina
In Pseudomonas aeruginosa,the dynamic activity of type IV pilus(TFP)is essential for various bacterial *** PilU isconsidered a homolog of the TFP disassembling motor PilT,its specific roles remain *** pilus visualizati... 详细信息
来源: 评论
An automatic annotation tool and reference database for T cell subtypes and states at single-cell resolution
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science Bulletin 2025年 第10期70卷 1659-1672页
作者: Shen, Wen-Kang Zhang, Chu-Yu Gu, Yi-Min Luo, Tao Chen, Si-Yi Yue, Tao Xie, Gui-Yan Liao, Yu Yuan, Yong Lei, Qian Guo, An-Yuan Department of Thoracic Surgery West China Biomedical Big Data Center West China Hospital Sichuan University Chengdu610041 China Hubei Bioinformatics & Molecular Imaging Key Laboratory College of Life Science and Technology Huazhong University of Science and Technology Wuhan430074 China College of Life Sciences University of Chinese Academy of Sciences Beijing101408 China Department of Rheumatology & Immunology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan430074 China
T cells have various subtypes and states with different functions. However, a reference list and automated annotation tool for T cell subtypes and states are lacking, which is critical for analyzing and comparing T ce... 详细信息
来源: 评论
Aloin ameliorates cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating gut microbiota
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Food science and Human Wellness 2025年 第2期14卷 550-568页
作者: Jingqian Su Jianbin Xiao Siyuan Chen Heng Zhao Xiaoni Zhang Zhihua Feng Kunsen Chen Biyun Guan Wenzhi Chen Youqiang Chen Duo Chen Qi Chen Fujian Key Laboratory of Innate Immune Biology Biomedical Research Center of South ChinaCollege of Life ScienceFujian Normal UniversityFuzhou 350117China The Public Service Platform for Industrialization Development Technology of Marine Biological Medicine and Products of the State Oceanic Administration Fujian Key Laboratory of Special Marine Bioresource Sustainable UtilizationSouthern Institute of OceanographyCollege of Life ScienceFujian Normal UniversityFuzhou 350117China
Most Aloe species are used as new food or functional food *** though widely known for its health benefits,the anti-inflammatory effects and underlying mechanisms of Aloin(Alo),an anthraquinone compound isolated from p... 详细信息
来源: 评论
Mobilization of heavy metals from floodplain sediments of the Yellow River during redox fluctuations
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Journal of Environmental sciences 2025年 第4期150卷 432-439页
作者: Fuyu Xie Xiaoqing Li Qingxiang Yang Ying Meng Fubo Luan Key Laboratory of Drinking Water Science and Technology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China College of Life Sciences Henan Normal UniversityXinxiang 453007China
The floodplain of the Yellow River is a typical area characterized by redox fluctuations and heavy metal ***,the mobilization behavior of heavy metals in floodplain sediments during redox fluctuations remains poorly *... 详细信息
来源: 评论
Scheme Design and Challenges of DNA Sequencing Terminal Equipment Based on Solid-State Nanopore Sequencing  4th
Scheme Design and Challenges of DNA Sequencing Terminal Equi...
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4th International Conference on Mechanical Design and Simulation, MDS 2024
作者: Zhao, Yuanzhe Zhang, Jie Sun, Zepeng Cao, Zheqi Xu, Liqun Li, Jian Key Laboratory of DGHD MOE School of Life Science and Technology Southeast University Nanjing China Industrial Research Institute Chengdu China
Nanopore sequencing has become the primary technology for modern DNA sequencing. Solid nanopores are favored for their cost-effectiveness, stability, and scalability, particularly for portable applications. This paper... 详细信息
来源: 评论