An efficient method for the diagnosis of breast cancer tumor is proposed based on Independent Component Analysis (ICA) and Least Square Support Vector Machine (LS-SVM). In order to save the expense of detection, first...
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On the basis of least squares support vector machine regression (LSSVR), an adaptive and iterative support vector machine regression algorithm based on chunking incremental learning (CISVR) is presented in this paper....
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A novel dynamic time delay neural network is proposed for ultrasonic motors identification and control in this paper. By introducing time delay neurons, the neural network identifier and controller of ultrasonic motor...
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An improved artificial immune algorithm with a dynamic threshold is presented. The calculation for the affinity function in the real-valued coding artificial immune algorithm is modified through considering the antib...
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An improved artificial immune algorithm with a dynamic threshold is presented. The calculation for the affinity function in the real-valued coding artificial immune algorithm is modified through considering the antibody's fitness and setting the dynamic threshold value. Numerical experiments show that compared with the genetic algorithm and the originally real-valued coding artificial immune algorithm, the improved algorithm possesses high speed of convergence and good performance for preventing premature convergence.
Identification of transcription factor binding sites from the upstream regions of genes is a highly important and unsolved problem. In this paper, we propose a novel framework for using evolutionary algorithm to solve...
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Identification of transcription factor binding sites from the upstream regions of genes is a highly important and unsolved problem. In this paper, we propose a novel framework for using evolutionary algorithm to solve this challenging issue. Under this framework, we use two prevalent evolutionary algorithms: genetic algorithm (GA) and particle swarm optimization (PSO) to find unknown sites in a collection of relatively long intergenic sequences that are suspected of being bound by the same factor. This paper represents binding sites motif to position weight matrix (PWM) and introduces how to code PWM to genome for GA and how to code it to particle for PSO. We apply these two algorithms to 5 different yeast saccharomyces cerevisiae transcription factor binding sites and CRP binding sites. The results on saccharomyces cerevisiae show that it can find the correct binding sites motifs, and the result on CRP shows that these two algorithms can achieve more accuracy than MEME and Gibbs sampler
Identification of Transcription Factor Binding Sites (TFBS) from the upstream region of genes remains a highly important and unsolved problem particularly in higher eukaryotic genomes. In this paper, we propose a nove...
Identification of Transcription Factor Binding Sites (TFBS) from the upstream region of genes remains a highly important and unsolved problem particularly in higher eukaryotic genomes. In this paper, we propose a novel approach to identify transcription factor binding sites. This approach combines greedy method and genetic algorithm (CGGA) to search conserved segment in the given sequence set. A new greedy method which can efficiently search a local optimal result is proposed. In order to solve the high complexity of this algorithm, we also give an effective improvement for this method. Then, we describe how to combine genetic algorithm with this greedy method to find the more optimal results. Greedy method is combined to the fitness function of the genetic algorithm. We apply this approach on two different TFBS sets and the results show that it can find correct result both effective and efficient, and for CRP binding sites, it get a more accurate result than Gibbs Sampler, AlignACE and MDGA.
Identification of transcription factor binding sites (TFBS) from the upstream region of genes remains a highly important and unsolved problem particularly in higher eukaryotic genomes. In this paper, we propose a new ...
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Identification of transcription factor binding sites (TFBS) from the upstream region of genes remains a highly important and unsolved problem particularly in higher eukaryotic genomes. In this paper, we propose a new approach to predict TFBS. This approach uses position weight matrix (PWM) to represent binding sites and uses genetic algorithm (GA) to search the best matrix. A new coding method so called multiple-variable coding is proposed in GA. We apply it on two transcription factors rebl and mgl. The result shows that this approach can find most of the known sites, which indicates that this method is very effective
Classification and regression are most interesting problems in the fields of pattern recognition. The regression problem can be changed into binary classification problem and least squares support vector machine can b...
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This paper describes a sub-object retrieval system based on a segmentation method. We also use dynamic partial function (DPF) and indexing by locality sensitive hashing (LSH) for improving system performance. Such a s...
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This paper describes a sub-object retrieval system based on a segmentation method. We also use dynamic partial function (DPF) and indexing by locality sensitive hashing (LSH) for improving system performance. Such a system is useful for finding a sub-object from a large image database. In order to obtain the sub-object from a sample image, we use a segmentation method to cut out the object. The system utilizes the segmentation results to capture the higher-level concept of images and gets a stable and accurate result. Experimental and comparison results, which are performed using a general purpose database containing 20,000 images, are encouraging
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