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Few-shot learning based histopathological image classification of colorectal cancer

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Intelligent Medicine 2024年第4期4卷 256-267页

作者： Rui Li Xiaoyan Li Hongzan Sun Jinzhu Yang Md Rahaman Marcin Grzegozek Tao Jiang Xinyu Huang Chen Li Key Laboratory of Intelligent Computing in Medical Image Ministry of EducationNortheastern UniversityShenyangLiaoning 110167China Cancer Hospital China Medical UniversityShenyangLiaoning 110122China Shengjing Hospital China Medical UniversityShenyang.Liaoning 110000China Institute for Medical Informatics University of LuebeckGermany Department of Knowledge Engineering University of Economics in KatowicePoland School of Intelligent Medicine Chengdu University of Traditional Chinese MedicineChengduSichuan 610075China International Joint Institute of Robotics and Intelligent Systems Chengdu University of Information TechnologyChengduSichuan 610225China School of Computer Science and Engineering University of New South WalesSydneyNSW 2052Australia

Background Colorectal cancer is a prevalent and deadly disease worldwide,posing significant diagnostic *** histopathologic image classification is often inefficient and *** some histopathologists use computer-aided diagnosis to improve efficiency,these methods depend heavily on exten-sive data and specific annotations,limiting their *** address these challenges,this paper proposes a method based on few-shot *** This study introduced a few-shot learning approach that combines transfer learning and contrastive learning to classify colorectal cancer histopathology images into benign and malignant *** model comprises modules for feature extraction,dimensionality reduction,and classification,trained using a combi-nation of contrast loss and cross-entropy *** this paper,we detailed the setup of hyperparameters:n-way,κ-shot,β,and the creation of support,query,and test *** Our method achieved over 98% accuracy on a query dataset with 35 samples per category using only 10 training samples per *** documented the model’s loss,accuracy,and the confusion matrix of the ***,we employed the t-SNE algorithm to analyze and assess the model’s classification *** The proposed model may demonstrate significant advantages in accuracy and minimal data depen-dency,performing robustly across all tested n-way,κ-shot *** consistently achieved over 93% accuracy on comprehensive test datasets,including 1916 samples,confirming its high classification accuracy and strong generalization *** research could advance the use of few-shot learning in medical diagnostics and also lays the groundwork for extending it to deal with rare,difficult-to-diagnose cases.

关键词： Colorectal cancer Few-shot learning Transfer learning Contrastive learning Histopathological images Benign and malignant categories

Bi-classifier with neighborhood aggregation for unsupervised domain adaptation

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Information Sciences 2025年 718卷

作者： Lü, Shuai Zhang, Xinyu Li, Zongze Li, Jingyao Kang, Meng Key Laboratory of Symbolic Computation and Knowledge Engineering (Jilin University) Ministry of Education Changchun 130012 China College of Computer Science and Technology Jilin University Changchun 130012 China College of Software Jilin University Changchun 130012 China

Recently, adversarial learning with bi-classifier has been confirmed to be effective in unsupervised domain adaptation, which can effectively promote the alignment of different distributions across domains. Most previous methods with bi-classifier exploit the output disagreement of the bi-classifier to learn transferable representations. However, only considering the disagreement between two classifiers cannot guarantee that the model performs well in the target domain. The main reason is that the model does not consider the local structure of the target domain data. To address this problem, we propose a Bi-Classifier with Neighborhood Aggregation (BCNA). Specifically, we provide two pseudo-labels for a target sample based on the nearest neighbor aggregation strategy. Then, we propose a self-supervised loss with two pseudo-labels based on confidence weight. In addition, we also propose a novel consistency regularization loss for bi-classifier. Unlike previous methods with bi-classifier, we achieve the goal of minimizing the disagreement between two classifiers from the perspective of different views of the sample. Our method can increase the discriminability of the model while ensuring the feature transferability. Extensive experiments show that our method has achieved state-of-the-art performance on three datasets that are widely used in unsupervised domain adaptation. © 2025 Elsevier Inc.

关键词： Bi-classifier Consistency regularization Neighborhood aggregation Self-supervision Unsupervised domain adaptation

A Survey of Sum-Product Networks Structural Learning

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SSRN

SSRN 2022年

作者： Xia, Riting Zhang, Yan Liu, Xueyan Yang, Bo School of Artificial Intelligence Jilin University Jilin Changchun130012 China School of Computer Science and Technology Jilin University Jilin Changchun130012 China Key Laboratory of Symbolic Computation and Knowledge Engineer Jilin University Ministry of Education Jilin Changchun130012 China College of Communication Engineering Jilin University Jilin Changchun130012 China

Sum-product networks (SPNs) in deep probabilistic models have made great progress in computer vision, robotics, neuro-symbolic artificial intelligence, natural language processing, probabilistic programming languages, and other fields. Compared with probabilistic graphical models and deep probabilistic models, SPNs can balance the tractability and expressive efficiency. In addition, SPNs remain more interpretable than deep neural models. The expressiveness and complexity of SPNs depend on its own structure. Thus, how to design an effective SPN structure learning algorithm that can balance expressiveness and complexity has become a hot research topic in recent years. In this paper, we review SPN structure learning comprehensively, including the motivation of SPN structure learning, a systematic review of related theories, the proper categorization of different SPN structure learning algorithms, several evaluation approaches and some helpful online resources. Moreover, we discuss some open issues and research directions for SPN structure learning. To our knowledge, this is the first survey to focus specifically on SPN structure learning, and we hope to provide useful references for researchers in related fields. © 2022, The Authors. All rights reserved.

关键词： Efficiency

An Enhanced Attentive Implicit Relation Embedding for Social Recommendation

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SSRN

SSRN 2022年

作者： Ma, Xintao Dong, Liyan Wang, Yuequn Li, Yongli Liu, Zhen Zhang, Hao College of Computer Science and Technology Jilin University Changchun130012 China Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin University Changchun130012 China School of Information Science and Technology Northeast Normal University Changchun130117 China Graduate School of Engineering Nagasaki Institute of Applied Science 536 Aba-machi Nagasaki851-0193 Japan

Nowadays, recommendation system incorporating social networks has attracted a lot of research attention and is widely used to understand user preferences regarding social relations. Besides, graph neural networks(GNNs) have proven to learn graph-structured data effectively. Thus, integrating GNN into social recommendations has become one challenge. Many approaches encode both the user-item interaction and social relations to learn user preference. However, the implicit relations are also crucial to understanding the features of users and items. Thus, we propose the attentive implicit relation embedding for social recommendation(SR-AIR), which models the user-item interaction and social networks, utilizing a graph attention mechanism on implicit relations of users and items. We evaluate our framework on two real-world datasets and demonstrate that our framework performs the best compared with state-of-the-art baselines © 2022, The Authors. All rights reserved.

关键词： Recommender systems

Spirit distillation: Precise real-time semantic segmentation of road scenes with insufficient data

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arXiv 2021年

作者： Wu, Zhiyuan Jiang, Yu Cui, Chupeng Yang, Zongmin Xue, Xinhui Qi, Hong Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin University Changchun China With College of Computer Science and Technology Jilin University Changchun China College of Computer Science and Technology Jilin University Changchun China

Semantic segmentation of road scenes is one of the key technologies for realizing autonomous driving scene perception, and the effectiveness of deep Convolutional Neural Networks(CNNs) for this task has been demonstrated. Stateof-art CNNs for semantic segmentation suffer from excessive computations as well as large-scale training data requirement. Inspired by the ideas of Fine-tuning-based Transfer Learning (FTT) and feature-based knowledge distillation, we propose a new knowledge distillation method for cross-domain knowledge transference and efficient data-insufficient network training, named Spirit Distillation(SD), which allow the student network to mimic the teacher network to extract general features, so that a compact and accurate student network can be trained for real-time semantic segmentation of road scenes. Then, in order to further alleviate the trouble of insufficient data and improve the robustness of the student, an Enhanced Spirit Distillation (ESD) method is proposed, which commits to exploit a more comprehensive general features extraction capability by considering images from both the target and the proximity domains as input. To our knowledge, this paper is a pioneering work on the application of knowledge distillation to few-shot learning. Persuasive experiments conducted on Cityscapes semantic segmentation with the prior knowledge transferred from COCO2017 and KITTI demonstrate that our methods can train a better student network (mIOU and high-precision accuracy boost by 1.4% and 8.2% respectively, with 78.2% segmentation variance) with only 41.8% FLOPs (see Fig. 1). Copyright © 2021, The Authors. All rights reserved.

关键词： Autonomous vehicles

Article Reranking by Memory-Enhanced key Sentence Matching for Detecting Previously Fact-Checked Claims

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arXiv 2021年

作者： Sheng, Qiang Cao, Juan Zhang, Xueyao Li, Xirong Zhong, Lei Key Laboratory of Intelligent Information Processing Institute of Computing Technology Chinese Academy of Sciences China University of Chinese Academy of Sciences China Key Lab of Data Engineering and Knowledge Engineering Renmin University of China China

False claims that have been previously fact-checked can still spread on social media. To mitigate their continual spread, detecting previously fact-checked claims is indispensable. Given a claim, existing works retrieve fact-checking articles (FC-articles) for detection and focus on reranking candidate articles in the typical two-stage retrieval framework. However, their performance may be limited as they ignore the following characteristics of FC-articles: (1) claims are often quoted to describe the checked events, providing lexical information besides semantics;and (2) sentence templates to introduce or debunk claims are common across articles, providing pattern information. In this paper, we propose a novel reranker, MTM (Memoryenhanced Transformers for Matching), to rank FC-articles using key sentences selected using event (lexical and semantic) and pattern information. For event information, we propose to finetune the Transformer with regression of ROUGE. For pattern information, we generate pattern vectors as a memory bank to match with the parts containing patterns. By fusing event and pattern information, we select key sentences to represent an article and then predict if the article fact-checks the given claim using the claim, key sentences, and patterns. Experiments on two real-world datasets show that MTM outperforms existing methods. Human evaluation proves that MTM can capture key sentences for explanations. The code and the dataset are at https://***/ICTMCG/MTM. © 2021, CC BY-SA.

关键词： Semantics

Size-Invariance Matters: Rethinking Metrics and Losses for Imbalanced Multi-object Salient Object Detection

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arXiv 2024年

作者： Li, Feiran Xu, Qianqian Bao, Shilong Yang, Zhiyong Cong, Runmin Cao, Xiaochun Huang, Qingming Institute of Information Engineering Chinese Academy of Sciences Beijing China School of Cyber Security University of Chinese Academy of Sciences Beijing China Key Laboratory of Intelligent Information Processing Institute of Computing Technology Chinese Academy of Sciences Beijing China School of Computer Science and Technology University of Chinese Academy of Sciences Beijing China Institute of Information Science Beijing Jiaotong University Beijing China School of Control Science and Engineering Shandong University Jinan China Key Laboratory of Machine Intelligence and System Control Ministry of Education Jinan China School of Cyber Science and Tech. Sun Yat-Sen University Shenzhen Campus China Key Laboratory of Big Data Mining and Knowledge Management Chinese Academy of Sciences Beijing China

This paper explores the size-invariance of evaluation metrics in Salient Object Detection (SOD), especially when multiple targets of diverse sizes co-exist in the same image. We observe that current metrics are size-sensitive, where larger objects are focused, and smaller ones tend to be ignored. We argue that the evaluation should be size-invariant because bias based on size is unjustified without additional semantic information. In pursuit of this, we propose a generic approach that evaluates each salient object separately and then combines the results, effectively alleviating the imbalance. We further develop an optimization framework tailored to this goal, achieving considerable improvements in detecting objects of different sizes. Theoretically, we provide evidence supporting the validity of our new metrics and present the generalization analysis of SOD. Extensive experiments demonstrate the effectiveness of our method. The code is available at https://***/Ferry-Li/SI-SOD. Copyright © 2024, The Authors. All rights reserved.

关键词： Object detection

Federated Coordinate Descent for Privacy-Preserving Multiparty Linear Regression

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arXiv 2022年

作者： Leng, Xinlin Li, Chenxu Xu, Weifeng Sun, Yuyan Wang, Hongtao School of Control and Computer Engineering North China Electric Power University Baoding071051 China School of Computer Science and Technology Shandong University of Finance and Economics Jinan250014 China Beijing Key Laboratory of IoT Information Security Institute of Information Engineering Chinese Academy of Sciences Beijing100093 China Hebei Key Laboratory of Knowledge Computing for Energy & Power Baoding071051 China

Federated linear regressions have been developed and applied in various domains, where multiparties collaboratively and securely perform optimization algorithms, e.g., Gradient Descent, to learn a set of optimal model weights. However, traditional Gradient-Descent based methods fail to solve problems which contain L1regularization in objective functions, such as lasso regression. In this paper, we present Federated Coordinate Descent, a new distributed scheme called FCD, to address this issue securely under multiparty scenarios. Specifically, through secure aggregation and noise perturbations, our scheme guarantees that: (1) no local information is leaked to other parties, and (2) global model weights are not exposed to cloud servers. The proposed FCD scheme fills the gap between multiparty secure learning and coordinate descent methods, and is applicable for general linear regressions, including linear, ridge, and lasso regressions. Theoretical analyses prove the security guarantees of our scheme against semi-honest attackers. Experimental results on three UCI datasets demonstrate that regressions under our FCD scheme are effective as centralized models. The performance evaluation on synthetic dataset also reveals that our scheme achieves efficient properties on computation cost and communication *** Codes 68Q32 Copyright © 2022, The Authors. All rights reserved.

关键词： Gradient methods

Enhanced Doubly Robust Learning for Debiasing Post-Click Conversion Rate Estimation

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arXiv 2021年

作者： Guo, Siyuan Zou, Lixin Liu, Yiding Ye, Wenwen Cheng, Suqi Wang, Shuaiqiang Chen, Hechang Yin, Dawei Chang, Yi School of Artificial Intelligence Jilin University China Baidu Inc. China International Center of Future Science Jilin University China Key Laboratory of Symbolic Computation Knowledge Engineering of Ministry of Education Jilin University China

Post-click conversion, as a strong signal indicating the user preference, is salutary for building recommender systems. However, accurately estimating the post-click conversion rate (CVR) is challenging due to the selection bias, i.e., the observed clicked events usually happen on users’ preferred items. Currently, most existing methods utilize counterfactual learning to debias recommender systems. Among them, the doubly robust (DR) estimator has achieved competitive performance by combining the error imputation based (EIB) estimator and the inverse propensity score (IPS) estimator in a doubly robust way. However, inaccurate error imputation may result in its higher variance than the IPS estimator. Worse still, existing methods typically use simple model-agnostic methods to estimate the imputation error, which are not sufficient to approximate the dynamically changing model-correlated target (i.e., the gradient direction of the prediction model). To solve these problems, we first derive the bias and variance of the DR estimator. Based on it, a more robust doubly robust (MRDR) estimator has been proposed to further reduce its variance while retaining its double robustness. Moreover, we propose a novel double learning approach for the MRDR estimator, which can convert the error imputation into the general CVR estimation. Besides, we empirically verify that the proposed learning scheme can further eliminate the high variance problem of the imputation learning. To evaluate its effectiveness, extensive experiments are conducted on a semi-synthetic dataset and two real-world datasets. The results demonstrate the superiority of the proposed approach over the state-of-the-art methods. The code is available at https://***/guosyjlu/MRDR-DL. Copyright © 2021, The Authors. All rights reserved.

关键词： Recommender systems