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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Jinli Fan Ruyi Shen Xiaodi Huang Yanju Zhang Guangxi Key Laboratory of Image and Graphic Intelligent Processing Guilin University of Electronic Technology Guilin China College of Computer Science and Technology Huaqiao University Xiamen China

ISBN: (数字)9798350386226

ISBN: (纸本)9798350386233

Transcription factors bind to specific sequences of DNA known as transcription factor binding sites (TFBSs) in order to regulate gene expression. Identifying TFBSs is crucial for deciphering gene expression mechanisms, understanding in vitro life characteristics, and drug design. In recent years, many deep learning methods that utilize only the sequence features or a combination of sequence and shape features have been developed to predict TFBSs. However, these methods have not fully considered the characteristics of TFBSs, and their encoding strategies are relatively simplistic, thereby failing to capture the complex dependencies hidden within TFBSs. To address these issues, we propose a novel deep neural network model called MATL, which integrates sequence and shape features for TFBSs prediction. The model employs techniques such as multi-scale convolution and Transformer, and combines different modules for feature extraction based on the distribution patterns of different feature matrices. Additionally, we introduce transfer learning to address the issue of unsatisfactory prediction results due to insufficient training data in some datasets. As the results indicate, MATL exhibits excellent predictive performance on 165 validated ChIP-seq datasets, surpassing state-of-the-art methods. We also conducted ablation experiments on sequence encoding, feature extraction, and shape modules used in this study, and demonstrated that these modules play a positive role in predicting TFBSs. Moreover, the results also indicated that transfer learning can improve prediction accuracy for some TFBSs datasets with small amounts of data. The source code of MATL is available at https://***/LittleWhiteKing/MATL.

关键词： Deep learning Shape Convolution Transfer learning Artificial neural networks Predictive models Feature extraction Transformers Data models Gene expression

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An Adaptive Physics-Informed Neural Network with Two-Stage Learning Strategy to Solve Partial Differential Equations

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Numerical Mathematics(Theory,Methods and Applications) 2023年第2期16卷 298-322页

作者： Shuyan Shi Ding Liu Ruirui Ji Yuchao Han School of Automation and Information Engineering Xi‘an University of TechnologyXi‘an 710048P.R.China National&Local Joint Engineering Research Center of Crystal Growth Equipment and System Integration Xi‘an 710048P.R.China Xi’an University of Technology Shannxi Key Laboratory of Complex System Control and Intelligent Information ProcessingXi‘an 710048P.R.China

Physics-Informed Neural Network(PINN)represents a new approach to solve Partial Differential Equations(PDEs).PINNs aim to solve PDEs by integrating governing equations and the initial/boundary conditions(I/BCs)into a loss ***,the imbalance of the loss function caused by parameter settings usually makes it difficult for PINNs to converge,*** they fall into local *** other words,the presence of balanced PDE loss,initial loss and boundary loss may be critical for the *** addition,existing PINNs are not able to reveal the hidden errors caused by non-convergent boundaries and conduction errors caused by the PDE near the ***,these problems have made PINN-based methods of limited use on practical *** this paper,we propose a novel physics-informed neural network,*** adaptive physics-informed neural network with a two-stage training *** algorithm adds spatio-temporal coefficient and PDE balance parameter to the loss function,and solve PDEs using a two-stage training process:pre-training and formal *** pre-training step ensures the convergence of boundary loss,whereas the formal training process completes the solution of PDE by balancing various loss *** order to verify the performance of our method,we consider the imbalanced heat conduction and Helmholtz equations often appearing in practical *** Klein-Gordon equation,which is widely used to compare performance,reveals that our method is able to reduce the hidden *** results confirm that our algorithm can effectively and accurately solve models with unbalanced loss function,hidden errors and conduction *** codes developed in this manuscript are publicy available at https://***/callmedrcom/ATPINN.

关键词： Physics informed neural networks partial differential equations two-stage learning scientific computing

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Data-driven risk assessment and early warning of learning situations 4

Data-driven risk assessment and early warning of learning si...

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4th International Conference on Computer Science and Educational Informatization, CSEI 2022

作者： Mi, Chunqiao Deng, Qingyou Zhao, Changhua Huaihua University Hunan Huaihua China Key Laboratory of Intelligent Control Technology for Wuling-Mountain Ecological Agriculture in Hunan Province Hunan Huaihua China Key Laboratory of Wuling-Mountain Health Big Data Intelligent Processing and Application in Hunan Province Universities Hunan Huaihua China

ISBN: (数字)9781839537882

ISBN: (纸本)9781839537882

At present, quality governance has become the internal demand of education reform and high-quality education system construction. First, this study analyzed the current research status and existing problems of early warning education in universities and colleges from the aspects of basic data, evaluation index, assessment method, and tool system application. Second, driven by learning situation big data analysis, this study puts forward a complete method system of risk assessment and early warning of learning situations, which consists of basic data collection and processing, index system construction and quantification, model construction and calculation, result expression and visualization, and a prototype information system was also realized by using modern software engineering and visualization technology. Finally, a specific course was taken as an example, and the application practice of learning situation risk assessment and early warning was carried out. The obtained results are very helpful to solve the problems of lagging early warning time, single evaluation factor, outdated technology and so on in traditional early warning education. It has reference significance for improving students' learning quality, teachers' teaching effect and early warning education management efficiency. © 2022 IET Conference Proceedings. All rights reserved.

关键词： Risk assessment

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Causal Invariant Hierarchical Molecular Representation for Out-of-distribution Molecular Property Prediction

Causal Invariant Hierarchical Molecular Representation for O...

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2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Wen, Xinlong Guo, Yifei Wei, Shuoying Long, Wenhan Zhu, Lida Zhu, Rongbo College of Informatics Huazhong Agricultural University Wuhan430070 China Shenzhen Institute of Nutrition and Health Huazhong Agricultural University Shenzhen518000 China Shenzhen Branch Guangdong Laboratory for Lingnan Modern Agriculture Genome Analysis Laboratory of the Ministry of Agriculture Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences Shenzhen518000 China Engineering Research Center of Intelligent Technology for Agriculture Ministry of Education Hubei Wuhan430074 China Key Laboratory of Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Hubei Wuhan430074 China

ISBN: (纸本)9798350386226

Molecular representation learning is widely used in the field of drug discovery, due to its ability to accurately capture the complex features of compounds in high-dimensional space. However, existing molecular representation learning models are prone to be influenced by spurious parts during distribution shifts (also known as out-of-distribution, or OOD), which results in models mistakenly treating these spurious parts as crucial features of molecules, thereby limiting the generalization capability of the models. To tackle this issue, a novel invariant molecular representation learning model, called Causal Invariant Hierarchical Molecular Representation Graph Neural Networks (CHiMoGNN), is proposed for OOD molecular property prediction. In CHiMoGNN, a Feature Enhancement (FE) module is designed to leverage the multi-level molecular parts to enhance the expression of invariant features, thereby enhancing the model's capability to capture key molecular information. In addition, a Cartesian Product based Environmental Impact (EI) module is adopted to generate counterfactual samples with environmental diversity. Consequently, these samples are utilized to train a classifier that maintains consistent performance across various environments. Extensive experiments on seven real-world datasets demonstrate that CHiMoGNN outperforms 9 state-of-the-art models, achieving a 5.73% increase in average ROC-AUC, and the results also show that CHiMoGNN can effectively maintain generalization in various distribution shifts. Code and datasets are available at https://***/Chertuion/CHiMoGNN. © 2024 IEEE.

关键词： Graph neural networks

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GPC-LIO-SAM:Lidar inertial odometry and mapping method for mobile robot with ground plane constraint

GPC-LIO-SAM:Lidar inertial odometry and mapping method for m...

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第43届中国控制会议

作者： Chong Cao Gang Peng Dingxin He Yihao Cao Yue Xu Zhang Deng School of Artificial Intelligence and Automation Huazhong University of Science and Technology Key Laboratory of Image Information Processing and Intelligent Control Ministry of Education Engineering Research Center of Autonomous Intelligent Unmanned Systems Ministry of Education Wuhan Lisai Technology Co. Ltd.

ISBN: (数字)9789887581581

ISBN: (纸本)9798350366907

Due to the limitation of the vertical angle resolution of the lidar sensor,the observation information in the vertical direction is reduced,resulting in the elevation cumulative drift phenomenon of many lidar SLAM algorithms in large-scale environment,which reduces the accuracy of pose estimation and the quality of *** order to solve this problem,based on LIO-SAM,this paper proposes a lidar SLAM algorithm with ground plane *** method can effectively extract the ground point cloud and obtain the plane normal vector,and construct the constraint relationship with the prior plane normal *** optimal state estimation is solved by nonlinear optimization method,which effectively reduces the elevation drift caused by the long-term operation of the system in large-scale *** paper compares the improved algorithm with A-LOAM,LeGO-LOAM and original LIO-SAM algorithms in challenging datasets such as KITTI,M2 DGR and *** results show that this method effectively improves the accuracy of pose estimation and the quality of mapping,and limit the elevation drift of mobile robot in ground operation,which has high application value.

关键词： Ground plane constraint elevation drift LIDAR simultaneous localization and mapping(SLAM)

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A Secure Parameter Self-Tuning control Scheme for Vehicle Platoons under DoS Attacks 13

A Secure Parameter Self-Tuning Control Scheme for Vehicle Pl...

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13th IEEE International Conference on CYBER Technology in Automation, control, and intelligent Systems, CYBER 2023

作者： Han, Qiaoni Cheng, Guowen Tang, Zhenning Liu, Chang School of Electrical and Information Engineering Tianjin Key Laboratory of Intelligent Unmanned Swarm Technology and System Tianjin University Tianjin300072 China Key Laboratory of System Control and Information Processing Ministry of Education Shanghai200240 China Center for Biomedical Engineering School of Information Science and Technology Fudan University Shanghai200433 China

ISBN: (纸本)9798350315196

In order to mitigate the adverse impact of denial of service (DoS) attacks, this work designs a parameter self-tuning controller based on fuzzy rules for vehicle platoons with vehicle-to-vehicle (V2V) communications. Aiming at achieving the cooperative adaptive cruise control (CACC) of the vehicles with a required inter-vehicle distance and the same velocity, while considering the possible DoS attacks, we propose a parameter self-tuning longitudinal controller combining linear control and fuzzy control to enhance the stability and resilience of the platoon systems. Firstly, by analyzing the dynamic characteristics of vehicles and the mechanism of DoS attacks, we establish the dynamic model of vehicle platoons and model the impact of random DoS attacks as a constant data transmission delay, whose probability distribution can be defined using the Bernoulli random variable. Then, a linear controller based on fuzzy control is designed for longitudinal control to guarantee that the platoon keeps a reference velocity and the specified inter-vehicle distance under DoS attacks. Finally, thorough simulations are performed and the detailed results show the performance of the secure longitudinal control scheme for vehicle platoons in terms of stability and security. © 2023 IEEE.

关键词： Fuzzy control

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Research on the Detection of Abnormal Cervical Cells Based on Improved YOLOv7

Research on the Detection of Abnormal Cervical Cells Based o...

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6th International Conference on intelligent Computing and Signal processing (ICSP)

作者： Xuewei Wang Shuang Yuan Lidong Yang Dawei Niu Inner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing Inner Mongolia University of Science and Technology School of Digtial and Intelligence Industry Inner Mongolia China

ISBN: (数字)9798350376548

ISBN: (纸本)9798350376555

Cervical cytologic screening is clinically important for the prevention and diagnosis of cervical cancer. Aiming at the many challenges in the detection of abnormal cervical cells, including the difficult detection of small targets of abnormal cervical cells, complex backgrounds, and uneven cell morphology, a detection algorithm for abnormal cervical cells based on improved YOLOv7 was proposed. The algorithm utilizes Deformable Convolutional Networks v2 (DCNv2) that adaptively de-tunes the scale and receptive field size to more effectively cope with the complexity and diversity of cervical cell images. The experimental results show that the improved YOLOv7 algorithm mAP achieves 57.26%, up to 73.88% accuracy, and 46.90% recall on the cervical abnormal cell dataset. Compared with the benchmark model, they increased by 4.07%, 3.39%, and 5.69%, respectively.

关键词： Accuracy Sensitivity Shape Prevention and mitigation Signal processing algorithms Signal processing Feature extraction Convolutional neural networks Detection algorithms Cervical cancer

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Bearing-Based Target Entrapping control of Multiple Uncertain Agents With Arbitrary Maneuvers

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IFAC-PapersOnLine 2023年第2期56卷 8821-8826页

作者： Haifan Su Ziwen Yang Shanying Zhu Cailian Chen Wenbin Yu Department of Automation Shanghai Jiao Tong University China Key Laboratory of System Control and Information Processing Ministry of Education of China Shanghai Engineering Research Center of Intelligent Control and Management

This paper is concerned with bearing-based cooperative target entrapping control of multiple uncertain agents with arbitrary maneuvers including shape deformation, rotations, scalings, etc. A leader-follower structure is used, where the leaders move with the predesigned trajectories, and the followers are steered by an estimation-based control method, integrating a distance estimator using bearing measurements and a stress matrix-based formation controller. The signum functions are used to compensate for the uncertainties so that the agents’ accelerations can be piecewise continuous and bounded to track the desired dynamics. With proper design of the leaders’ trajectories and a geometric configuration, an affine matrix is determined so that the inter-agent relative bearings can be persistently exciting since the bearing rates are related to different weighted combinations of the affine matrix vectors. The asymptotic convergence of the estimation and control error is proved using Filipov properties and cascaded system theories. A sufficient condition for inter-agent collision avoidance is also proposed. Finally, simulation results are given to validate the effectiveness of the method.

关键词： Target entrapping control bearing measurement persistent excitation uncertainty

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NPIPVis:A visualization system involving NBA visual analysis and integrated learning model prediction

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Virtual Reality & intelligent Hardware 2022年第5期4卷 444-458页

作者： Zhuo SHI Mingrui LI Meng WANG Jing SHEN Wei CHEN Xiaonan LUO Department of Art and Design University of Guilin Electronic TechnologyGuilin 541004China Department of Computer and Information Security University of Guilin Electronic TechnologyGuilin 541004China Department of Guangxi Key Laboratory of Image and Graphic Intelligent Processing University of Guilin Electronic TechnologyGuilin 541004China Department of State Key Laboratory of CAD&CG University of ZhejiangHangzhou 310058China

Background Data-driven event analysis has gradually become the backbone of modern competitive sports analysis. Competitive sports data analysis tasks increasingly use computer vision and machine-learning models for intelligent data analysis. Existing sports visualization systems focus on the player–team data visualization, which is not intuitive enough for team season win–loss data and game time-series data visualization and neglects the prediction of all-star players. Methods This study used an interactive visualization system designed with parallel aggregated ordered hypergraph dynamic hypergraphs, Calliope visualization data story technology,and i Storyline narrative visualization technology to visualize the regular statistics and game time data of players and teams. NPIPVis includes dynamic hypergraphs of a team’s wins and losses and game plot narrative visualization components. In addition, an integrated learning-based all-star player prediction model, SRR-voting, which starts from the existing minority and majority samples, was proposed using the synthetic minority oversampling technique and Random Under Sampler methods to generate and eliminate samples of a certain size to balance the number of allstar and average players in the datasets. Next, a random forest algorithm was introduced to extract and construct the features of players and combined with the voting integrated model to predict the all-star players, using GridSearch CV, to optimize the hyperparameters of each model in integrated learning and then combined with five-fold cross-validation to improve the generalization ability of the model. Finally, the SHapley Additive ex Planations(SHAP) model was introduced to enhance the interpretability of the model. Results The experimental results of comparing the SRR-voting model with six common models show that the accuracy, F1-score, and recall metrics are significantly improved, which verifies the effectiveness and practicality of the SRR-voting model. Conc

关键词： Sports visualization Parallel aggregated ordered hypergraph Calliope IStoryline Integrated learning SHAP model

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Generalized Zero-shot Learning Based on Dual Latent Space Reconstruction

Generalized Zero-shot Learning Based on Dual Latent Space Re...

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2022 International Conference on intelligent Systems, Communications, and Computer Networks, ISCCN 2022

作者： Xu, Yangdongfang Yang, Guan Liu, Xiaoming Liu, Yang School of Computer Science Zhongyuan University of Technology Zhengzhou China Henan Key Laboratory on Public Opinion Intelligent Analysis Zhengzhou China Zhengzhou Key Laboratory of Text Processing and Image Understanding Zhengzhou China School of Telecommunications Engineering Xidian University Xi’an China

ISBN: (纸本)9781510657342

Generalized Zero-Shot Learning (GZSL) is characterized as a training process that comprises visual samples from seen classes and semantic samples from seen and unseen classes, followed by a testing process that classifies visual samples from seen and unseen classes. Existing zero-shot learning (ZSL) approaches suffer from domain shift and information loss issues as a result of class differences between visible and unseen classes, as well as uneven image distribution. In this study, a generalized zero-shot learning strategy based on dual latent space reconstruction (DLR-GZSL) is proposed. The method aims to establish a latent space of shared semantic and visual information, uses dual learning to align different modal representations to alleviate the domain shift problem, uses triplet loss to improve intra-class diversity and inter-class separability of the generated samples, and uses information bottleneck to retain as much valid generated feature information as possible to reduce information loss. Experiments on the CUB, SUN, AWA1, and AWA2 datasets reveal that the suggested method has more accurate than previous methods, demonstrating its effectiveness. © 2022 SPIE.

关键词： Zero-shot learning

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