检索结果-内蒙古大学图书馆

A drug-eluting balloon catheter coated with chitosan and paclitaxel-loaded poloxamer-stabilized PLA microparticles for the effective treatment of cholangiocarcinoma

引用

Journal of Industrial and Engineering Chemistry 2025年

作者： Lee, Jin Sil Jang, Jaehee Oh, Hyeryeon Lee, Eunhye Lee, Don Haeng Son, Panmo Sung, Daekyung Choi, Won Il Center for Bio-Healthcare Materials Bio-Convergence Materials R&D Division Korea Institute of Ceramic Engineering and Technology 202 Osongsaengmyeong 1-ro Osong-eup Heungdeok-gu Chungbuk Cheongju28160 Korea Republic of Daegu41061 Korea Republic of R&D Division NEXTBIOMEDICAL CO. LTD. 6 Venture-ro 100 beon-gil Yeonsu-gu Incheon22013 Korea Republic of School of Integrative Engineering Chung-Ang University Seoul06974 Korea Republic of School of Materials Science and Engineering Gwangju Institute of Science and Technology Cheomdan-gwagiro 123 Buk-gu Gwangju61005 Korea Republic of Division of Gastroenterology Department of Internal Medicine Inha University Hospital Inha University School of Medicine Incheon22332 Korea Republic of Department of Applied Bioengineering of Convergence Science and Technology Seoul National University Seoul08826 Korea Republic of

Liver cancer is one of the most common causes of death, and cholangiocarcinoma (CCA) is the second most common type, usually treated with surgical resection;however, the resectable area is often small, leading to high recurrence. Balloon catheter insertion has been used to alleviate primary CCA symptoms. However, current drug-eluting balloon catheters are unable to provide continuous drug release, resulting in short-term effects and insufficient tumor suppression. Therefore, drug delivery systems and mucoadhesive polymers in drug-eluting balloon catheters have been proposed as alternatives. In this study, we developed paclitaxel (PTX)-loaded, poloxamer-stabilized PLA microparticles (PTX@PPMP) with high drug-loading capacity. We then created a PTX@PPMP-coated balloon catheter using mucoadhesive chitosan (PBCC) through spraying. PTX@PPMP particles were micron sized (1000–1400 nm), exhibited good colloidal stability, and enabled sustained pH-dependent drug release. In CCA cancer cell lines, PPMP did not exhibit significant cytotoxicity, and PTX@PPMP demonstrated an anticancer effect comparable to PTX, even though it had a 16-fold lower efficacy compared to PTX dose. Furthermore, in a xenograft model, the PBCC membrane dose-dependently inhibited the tumor volume without causing acute toxicity. These results indicate that the PBCC, as a novel drug-coated balloon catheter, can improve CCA chemotherapy and have further roles in balloon catheters applications. © 2025 The korean Society of Industrial and Engineering Chemistry

关键词： Chitosan

来源：评论

学校读者我要写书评

暂无评论

Enhanced wound healing via ROS-triggered release of ascorbyl tetraisopalmitate loaded in ferrocene-based polymer nanoparticles

引用

Redox Biology 2025年 84卷 103659页

作者： Yu, Sohyeon Lee, Minhyeok Seo, Dongseong Kim, Hyungjun Park, Chan-Su Sung, Daekyung Center for Bio-Healthcare Materials Bio-Convergence Materials R&D Division Korea Institute of Ceramic Engineering and Technology Cheongju 28160 South Korea Department of Chemical and Biomolecular Engineering Yonsei University Seoul 03722 South Korea Department of Pharmaceutics College of Pharmacy Chungbuk National University 1 Chungdae-ro Seowon-gu Cheongju 28644 South Korea Department of Applied Bioengineering of Convergence Science and Technology Seoul National University Seoul 08826 South Korea Department of Chemistry and Bioscience Kumoh National Institute of Technology 61 Daehak-ro Gumi 39177 South Korea

Ascorbyl tetraisopalmitate (AT), a vitamin C derivative, exhibits better stability and transdermal absorption than vitamin C and shows potential for skin whitening and wound healing. However, their low water solubility and specific storage requirements limit their application. To overcome these limitations, in this study, we aimed to develop AT-loaded ferrocene polymer nanoparticles (AT@FNPs) using biocompatible amphiphilic polymers. The nanoprecipitated nanoparticles exhibited enhanced AT stability, loading efficiency, and controlled release in reactive oxygen species (ROS)-rich wound environments. Moreover, the ROS ROS-trigger of AT@FNPs facilitated targeted drug release and ROS scavenging, thereby enhancing the antioxidant activity. The release of AT from the AT@FNPs in wounds promoted cell proliferation and accelerated wound closure in a mouse model. Overall, our findings highlight the potential of the developed ROS-triggered AT@FNPs as smart drug delivery systems for wound healing and skin treatment. © 2025 The Authors

关键词： Antioxidant activity Ascorbyl tetraisopalmitate Ferrocene polymer ROS trigger Wound healing

来源：评论

学校读者我要写书评

暂无评论

A vision system for UAV position control

A vision system for UAV position control

引用

IEEE Conference on Aerospace

作者： Baik, Kyeonghoon Shin, Jinok Ji, Sanki Shon, Woonghee Park, Sangdeok Division for Applied Robot Technology Korea Institute of Industrial Technology Korea Republic of

ISBN: (纸本)9781424473502

In this paper, we propose a vision-based control system for the localization of an unmanned aerial vehicle (UAV) which equips on-board cameras. The proposed approach is combined a visual odometer with inertial measurement from IMU and pressure signal which compensate attitude and altitude, respectively. For the autonomous control of a UAV, we consider only natural landmarks provided by a feature tracking algorithm without the help of visual beacons or landmarks at known positions. The displacement of the UAV is estimated by the homography, the relationship between a pair of points. The experimental results show that it is possible to extract useful position information from the proposed vision system even when the UAV flies high, and the information can be used temporary position control of UAVs during GPS failure. © 2011 IEEE.

关键词： Position control

来源：评论

学校读者我要写书评

暂无评论

Extracting extrinsic parameters of a laser scanner and a camera using EM

Extracting extrinsic parameters of a laser scanner and a cam...

引用

ICCAS-SICE 2009 - ICROS-SICE International Joint Conference 2009

作者： Park, Jae-Han Shin, Yong-Deuk Park, Kyung-Wook Baeg, Seung-Ho Baeg, Moon-Hong Division of Applied Robot Technology Korea Institute of Industrial Technology Seoul Korea Republic of

ISBN: (纸本)9784907764296

The robot's ability of perceiving their environments is primary functionality for a number of applications such as the rescue, navigation and manipulation. In these applications, the 3D colored map image is very useful information because it provides not only scene data but spatial data. For acquiring reliable 3D colored maps from the camera and the 3D laser scan system, one of the fundamental issues is the extrinsic calibration that calculates the rigid transformation (i.e., rotation and translation) between camera and laser coordinate system. In this paper we propose a novel method of getting extrinsic parameters which is insensitive to the noise of laser scanner measurements. Our approach introduces Expectation-Maximization(EM) algorithm to robust estimation of the relations between the camera and the laser scanner coordinate system in noisy environments. Simulations at various conditions with adding the laser measurement noise are performed to verify the effectiveness of our approach, and they show improved performances in estimating the extrinsic calibration parameters. © 2009 SICE.

关键词： Cameras

来源：评论

学校读者我要写书评

暂无评论

Development of task planner for u-intelligent educational robots

Development of task planner for u-intelligent educational ro...

引用

ICROS-SICE International Joint Conference 2009, ICCAS-SICE 2009

作者： Ko, Woohyun Han, Jaeseong Ji, Sanghoon Nam, Kyungtae Lee, Sangmoo Shon, Woonghee Division of Applied Robot Technology Korea Institute of Industrial Technology Ansan Korea Republic of

ISBN: (纸本)9784907764333

Recently, robots have penetrated the education market. But the power train for commercializing the robots has not been prepared yet due to chasm between developers and customers. Thus, we present a tool for u-intelligent educational robots to help customers design robot contents easily. To do so, our tool has several features. First, the tool is based on a behavior-based control architecture for human-robot-interaction. Second, the tool has behavior categories for convenience. Finally, robot contents are based on commercial multi-media for compatibility with established educational contents. Effectiveness and practicality of our tools are verified by physical implementation for commercial educational robots. © 2009 SICE.

关键词： Human robot interaction

来源：评论

学校读者我要写书评

暂无评论

Vibration occurrence estimation and avoidance for vision inspection system 2

引用

2nd International Conference on robot Intelligence technology and Applications, RiTA 2013

作者： Seo, Kap-Ho Park, Yongsik Yun, Sungjo Park, Sungho Park, Jeong Woo Applied Technology Division Korea Institute of Robot and Convergence San 31 Hyoja-dong Nam-gu Pohang Gyeongbuk790-784 Korea Republic of

ISBN: (纸本)9783319055817

Disturbance / vibration reduction is critical in many applications using machine vision. The off-focusing or blurring error caused by vibration degrades its performance. Instead of going with the more familiar approach like vibration absorber, a real-time disturbance estimation and avoidance is proposed, Instantaneous motion due to the disturbance is sensed by an accelerometer inertial measurement unit (IMU). Modeling of periodic vibration is done to provide better performance. According to its modeling, the algorithm for vibration avoidance was described. © Springer International Publishing Switzerland 2014.

关键词： Inspection

来源：评论

学校读者我要写书评

暂无评论

Dynamic control of parallel manipulator

Dynamic control of parallel manipulator

引用

1st International Conference on robot Intelligence technology and Applications, RiTA 2012

作者： Seo, Kap-Ho Park, Yongsik Yun, Sungjo Park, Sungho Jun, Jungsoo Min, Jeongtack Applied Technology Division Korea Institute of Robot and Convergence San 31 Hyoja-dong Nam-gu Pohang Gyeongbuk 790-784 Korea Republic of

ISBN: (纸本)9783642373732

Parallel manipulator with longer legs and heavy load is applied in most of the current high fidelity simulators, which is used to simulate various motions in different environments by exporting varying displacement and orientation. A novel model-based controller for 6-DOF parallel manipulator with gravity compensation is developed, in order to improve the control precision of 6-DOF parallel manipulator with high speed and heavy load. The effectiveness of the proposed algorithm will be discussed based on experiments. © 2013 Springer-Verlag.

关键词： Manipulators

来源：评论

学校读者我要写书评

暂无评论

Development of P-SURO II Hybrid Autonomous Underwater Vehicle and its Experimental Studies

引用

Journal of institute of Control, robotics and Systems 2013年第9期19卷 813-821页

作者： Li, Ji-Hong Lee, Mun-Jik Park, Sang-Heon Kim, Jung-Tae Kim, Jong-Geol Suh, Jin-Ho Applied Technology Division Korea Institute of Robot and Convergence Korea Republic of

In this paper, we present the development of P-SURO II hybrid AUV (Autonomous Underwater Vehicle) which can be operated in both of AUV and ROV (Remotely Operated Vehicle) modes. In its AUV mode, the vehicle is supposed to carry out some of underwater missions which are difficult to be achieved in ROV mode due to the tether cable. To accomplish its missions such as inspection and maintenance of complex underwater structures in AUV mode, the vehicle is required to have high level of autonomy including environmental recognition, obstacle avoidance, autonomous navigation, and so on. In addition to its systematic development issues, some of algorithmic issues are also discussed in this paper. Various experimental studies are also presented to demonstrate these developed autonomy algorithms. © ICROS 2013.

关键词： Hybrid systems

来源：评论

学校读者我要写书评

暂无评论

Sensor fusion localization system for outdoor mobile robot

Sensor fusion localization system for outdoor mobile robot

引用

ICCAS-SICE 2009 - ICROS-SICE International Joint Conference 2009

作者： Lee, Donghoon Son, Sukyung Yang, Kwangwoong Park, Jonghwan Lee, Hogil Intelligent Robot Engineering University of Science and Technology Ansan Korea Republic of Division for Applied Robot Techonology Korea Institute of Industrial Technology Ansan Korea Republic of

ISBN: (纸本)9784907764296

The purpose of this study is to develop sensor fusion loclization of autonomous mobile robot for outdoor environment. We merge 2 localization models;a Camera sensor with Particle filter and two GPS sensors with Kalman filter. The marks on the load such as lane, arrow, cross road and speed hump, etc., are most important information in urban environment. The camera device is useful to detect road landmarks, because the information printed on the road are color-based model. We use Delaunay triangulation method to extract landmark points in the interest region. The robot finds out the position by comparing these landmark points with a map with Particle filter algorithm. We also use GPS that provides global position directly. The GPS, however, has large drift position data caused by intentional pseudo noise and slow acquisition time for mobile robot. In this paper, a sensor fusion localization system is proposed to get the robot's reasonable position by fusing these 2 localization models that compensate the weak points each other. © 2009 SICE.

关键词： Mobile robots

来源：评论

学校读者我要写书评

暂无评论

Development of P-SURO II Hybrid AUV and its Experimental Study

Development of P-SURO II Hybrid AUV and its Experimental Stu...

引用

Oceans 2013 - Norway

作者： J. H. Li M. J. Lee S. H. Park J. G. Kim J. T. Kim J. H. Suh Applied Technology Division Korea Institute of Robot and Convergence

ISBN: (纸本)9781479900022

P-SURO II is a hybrid AUV which can be operated in both of ROV and AUV modes. The AUV mode is supposed to carry out some of underwater missions which are difficult to be accomplished by ROV mode due to its tether cable. To complete the underwater missions such as inspection and maintenance of complex structures in AUV mode, the vehicle is required to have high level of autonomy including obstacle avoidance, autonomous navigation, and so on. In this paper, we will discuss some of systematic and algorithmic issues in the development of such kind hybrid vehicles. Experimental studies on the development of underwater hybrid inertial navigation system and SLAM (simultaneous localization and mapping) method in a certain water tank environment are also discussed.

关键词： Hybrid AUV SLAM Underwater localization Obstacle avoidance Path planning

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：