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Programmable cell aggregation by a synthetic biosilicification approach

iscience 2025年第6期28卷

作者： Wang, Qing Sun, Jing Zang, Lei Yao, Huaxiong Wang, Lin Zhu, Runtao Li, Jie Zeng, Simin Tang, Hongting Wang, Teng Liu, Ji Wang, Bo Li, Bo Liu, Zhiyuan Dai, Zhuojun State Key Laboratory of Quantitative Synthetic Biology Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin 150001 China Center of Neural Engineering CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Artificial Intelligence and Robotics for Society Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China Department of Mechanical and Energy Engineering Southern University of Science and Technology Shenzhen 518055 China Department of Civil Engineering University of Nottingham Ningbo China 199 Taikang East Road Ningbo 315100 China

Programmable cell aggregation offers valuable insights into the natural development of synthetic multicellular systems and enables precise control over spatial organization and material structuring. Previous efforts have focused on modifying cells with designed organic-based adhesive modules and assembling cells into defined patterns. Here, we present a different approach to guide cell assembly by tuning the organic-inorganic interactions. Our method involves engineering cells to express a silicifying peptide on their surfaces, which promotes silica deposition on the cell walls. This peptide simultaneously binds to the silica synthesized on adjacent cells, triggering cell clustering. The engineered cells exhibit rapid aggregation, with approximately 95% of cells assembling within 15 min. We further show that this capability can facilitate materials assembly and chemical production. Our biosilicification-based approach offers novel insights into natural multicellularity mechanisms and holds potential for applications in biomanufacturing and materials engineering. © 2025 The Author(s)

关键词： Bioengineering Biomaterials Synthetic biology

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AUV path planning, navigation, and control using geophysical data

AUV path planning, navigation, and control using geophysical...

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OCEANS - Europe

作者： J. Quintas N. Hung N. Crasta F. Curado-Teixeira P. Lima A. Pascoal I. Kaminer Laboratory of Robotics and Engineering Systems (LARSyS) ISR/IST University of Lisbon Portugal Department of Electronics Telecommunications and Informatics University of Aveiro Portugal Department of Mechanical and Aerospace Engineering Naval Postgraduate School Monterey CA USA

We propose an integrated motion planning, geophysical navigation, and control (PNC) system for autonomous underwater vehicles (AUVs) that makes explicit use of geophysical information for both planning and navigation. The PNC system exploits the information provided by geomagnetic features observed on the sea-floor to correct the inevitable drift in the vehicle position estimates using dead-reckoning (DR). The three components of the PNC system are: a path planner that enhances the exploratory strength of the Rapidly-exploring Random Tree (RRT) algorithm with transition tests to choose new potential states, a sequential estimation algorithm, and a path following controller. The performance of the system is assessed via hardware in the loop (HIL) simulations to illustrate the significance of using magnetic data for navigation of AUVs. The results obtained are encouraging for inwater tests with an autonomous vehicle of the Medusa class aiming at the validation of the proposed combined system in real-time experiments.

关键词： Navigation Noise measurement Path planning Sea measurements Position measurement Magnetometers

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MRPB 1.0: A unified benchmark for the evaluation of mobile robot local planning approaches

arXiv

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arXiv 2020年

作者： Wen, Jian Zhang, Xuebo Bi, Qingchen Pan, Zhangchao Feng, Yanghe Yuan, Jing Fang, Yongchun The Institute of Robotics and Automatic Information System College of Artificial Intelligence Nankai University Tianjin300350 China The Tianjin Key Laboratory of Intelligent Robotics Nankai University Tianjin300350 China The School of Marine Science and Technology Northwestern Polytechnical University Xi'an710072 China The Faculty of Robot Science and Engineering Northeastern University Shenyang110000 China The College of Systems Engineering National University of Defense Technology Changsha410073 China

Local planning is one of the key technologies for mobile robots to achieve full autonomy and has been widely investigated. To evaluate mobile robot local planning approaches in a unified and comprehensive way, a mobile robot local planning benchmark called MRPB 1.0 is newly proposed in this paper. The benchmark facilitates both motion planning researchers who want to compare the performance of a new local planner relative to many other state-of-the-art approaches as well as end users in the mobile robotics industry who want to select a local planner that performs best on some problems of interest. We elaborately design various simulation scenarios to challenge the applicability of local planners, including large-scale, partially unknown, and dynamic complex environments. Furthermore, three types of principled evaluation metrics are carefully designed to quantitatively evaluate the performance of local planners, wherein the safety, efficiency, and smoothness of motions are comprehensively considered. We present the application of the proposed benchmark in two popular open-source local planners to show the practicality of the benchmark. In addition, some insights and guidelines about the design and selection of local planners are also provided. The benchmark website [1] contains all data of the designed simulation scenarios, detailed descriptions of these scenarios, and example code. Copyright © 2020, The Authors. All rights reserved.

关键词： Mobile robots

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Optomechanical dissipative solitons (vol 600, pg 75, 2021)

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NATURE 2022年第7896期602卷 E24-E24页

作者： Zhang, Jing Peng, Bo Kim, Seunghwi Monifi, Faraz Jiang, Xuefeng Li, Yihang Yu, Peng Liu, Lianqing Liu, Yu-xi Alu, Andrea Yang, Lan Department of Electrical and Systems Engineering Washington University St. Louis MO USA Department of Automation Tsinghua University Beijing P. R. China Photonics Initiative Advanced Science Research Center City University of New York New York NY USA Physics Program Graduate Center City University of New York New York NY USA State Key Laboratory of Robotics Shenyang Institute of Automation Chinese Academy of Sciences Shenyang P. R. China Institute of Microelectronics Tsinghua University Beijing P. R. China

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Dendrite Net with Acceleration Module for Faster Nonlinear Mapping and System Identification

arXiv

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arXiv 2020年

作者： Liu, Gang Pang, Yajing Yin, Shuai Niu, Xiaoke Wang, Jing Wan, Hong School of Electrical and Information Engineering Zhengzhou University Zhengzhou450001 China Institute of Robotics and Intelligent Systems Xi'an Jiaotong University Xi'An710049 China Henan Provincial Key Laboratory of Brain Science and Brain-Computer Interface Technology Zhengzhou450001 China

Nonlinear mapping is an essential and common demand in online systems, such as sensor systems and mobile phones. Accelerating nonlinear mapping will directly speed up online systems. Previously the authors of this paper proposed a Dendrite Net (DD) with enormously lower time complexity than the existing nonlinear mapping algorithms;however, there still are redundant calculations in DD. This paper presents a DD with an acceleration module (AC) to accelerate nonlinear mapping further. We conduct three experiments to verify whether DD with AC has lower time complexity while retaining DD's nonlinear mapping properties and system identification properties: The first experiment is the precision and identification of unary nonlinear mapping, reflecting the calculation performance using DD with AC for basic functions in online systems. The second experiment is the mapping precision and identification of the multi-input nonlinear system, reflecting the performance for designing online systems via DD with AC. Finally, this paper compares the time complexity of DD and DD with AC and analyzes the theoretical reasons through repeated experiments. Results: DD with AC retains DD's excellent mapping and identification properties and has lower time complexity. Significance: DD with AC can be used for most engineering systems, such as sensor systems, and will speed up computation in these online systems. The code of DD with AC is available on GitHub:Gang neuron. © 2020, CC BY-NC-SA.

关键词： Online systems

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Roadmap on soft robotics: multifunctionality, adaptability and growth without borders

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Multifunctional Materials 2022年第3期5卷 032001-032001页

作者： Mazzolai, Barbara Mondini, Alessio Del Dottore, Emanuela Margheri, Laura Carpi, Federico Suzumori, Koichi Cianchetti, Matteo Speck, Thomas Smoukov, Stoyan K. Burgert, Ingo Keplinger, Tobias Siqueira, Gilberto De Freitas Vanneste, Felix Goury, Olivier Duriez, Christian Nanayakkara, Thrishantha Vanderborght, Bram Brancart, Joost Terryn, Seppe Rich, Steven I. Liu, Ruiyuan Fukuda, Kenjiro Someya, Takao Calisti, Marcello Laschi, Cecilia Sun, Wenguang Wang, Gang Wen, Li Baines, Robert Patiballa, Sree Kalyan Kramer-Bottiglio, Rebecca Rus, Daniela Fischer, Peer Simmel, Friedrich C Lendlein, Andreas Bioinspired Soft Robotics Laboratory Istituto Italiano di Tecnologia Italy Department of Industrial Engineering University of Florence Via di S. Marta 3 Florence50139 Italy Department of Mechanical Engineering Tokyo Institute of Technology Ookayama Meguro Tokyo152-8550 Japan The BioRobotics Institute Scuola Superiore Sant’Anna Pisa56025 Italy Department of Excellence in Robotics & AI Scuola Superiore Sant’Anna Pisa56025 Italy Plant Biomechanics Group & Botanic Garden and Cluster of Excellence livMatS @ FIT University of Freiburg Germany Active and Intelligent Materials Laboratory Queen Mary University of London LondonE1 4NS United Kingdom Wood Materials Science Institute for Building Materials ETH Zurich Zurich8093 Switzerland Cellulose and Wood Materials Laboratory Empa Swiss Federal Laboratories for Materials Science and Technology Dübendorf8600 Switzerland University of Lille Inria CNRS Centrale Lille UMR 9189 CRIStAL LilleF-59000 France Dyson School of Design Engineering Imperial College London United Kingdom Vrije Universiteit Brussel and imec Brussels Belgium Thin-Film Device Laboratory RIKEN 2-1 Hirosawa Saitama Wako351-0198 Japan Center for Emergent Matter Science RIKEN 2-1 Hirosawa Saitama Wako351-0198 Japan Electrical and Electronic Engineering and Information Systems The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo113-8656 Japan The BioRobotics Institute Scuola Superiore Sant’Anna Italy Lincoln Institute for Agri-food Technology University of Lincoln Lincoln United Kingdom Department of Mechanical Engineering National University of Singapore Singapore School of Mechanical Engineering and Automation Beihang University Beijing100191 China Department of Mechanical Engineering and Materials Science Yale University New HavenCT06511 United States CSAIL MIT Schwarzman College of Computing United States Max Planck Institute for Intelligent Systems Heisenbergstr. 3 Stuttgart70569 Germany Institute of Physical Chemistry

Soft robotics aims at creating systems with improved performance of movement and adaptability in unknown, challenging, environments and with higher level of safety during interactions with humans. This Roadmap on Soft robotics covers selected aspects for the design of soft robots significantly linked to the area of multifunctional materials, as these are considered a fundamental component in the design of soft robots for an improvement of their peculiar abilities, such as morphing, adaptivity and growth. The roadmap includes different approaches for components and systems design, bioinspired materials, methodologies for building soft robots, strategies for the implementation and control of their functionalities and behavior, and examples of soft-bodied systems showing abilities across different environments. For each covered topic, the author(s) describe the current status and research directions, current and future challenges, and perspective advances in science and technology to meet the challenges. © 2022 The Author(s). Published by IOP Publishing Ltd.

关键词： Machine design

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Correction to: SleepBoost: a multi‑level tree‑based ensemble model for automatic sleep stage classification

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Medical & biological engineering & computing 2024年第9期62卷 2785页

作者： Akib Zaman Shiu Kumar Swakkhar Shatabda Iman Dehzangi Alok Sharma Computer Science and Artificial Intelligence Laboratory (CSAIL) Electrical Engineering and Computer Science Department Massachusetts Institute of Technology Cambridge MA USA. School of Electrical & Electronics Engineering Fiji National University Suva Fiji. shiu.kumar@fnu.ac.fj. Centre for Artificial Intelligence and Robotics (CAIR) United International University Dhaka Bangladesh. Department of Computer Science Rutgers University Camden NJ USA. Center for Computational and Integrative Biology Rutgers University Camden USA. Laboratory for Medical Science Mathematics RIKEN Center for Integrative Medical Sciences Yokohama 230‑0045 Japan. Institute for Integrated and Intelligent Systems Griffith University Nathan Brisbane QLD Australia.

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Author Correction: Super-resolution multicolor fluorescence microscopy enabled by an apochromatic super-oscillatory lens with extended depth-of-focus

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Nature communications 2024年第1期15卷 1510页

作者： Wenli Li Pei He Dangyuan Lei Yulong Fan Yangtao Du Bo Gao Zhiqin Chu Longqiu Li Kaipeng Liu Chengxu An Weizheng Yuan Yiting Yu Ningbo Institute of Northwestern Polytechnical University College of Mechanical Engineering Northwestern Polytechnical University Xi'an 710072 China. Key Laboratory of Micro/Nano Systems for Aerospace (Ministry of Education) Northwestern Polytechnical University Xi'an 710072 China. Shaanxi Province Key Laboratory of Micro and Nano Electro-Mechanical Systems Northwestern Polytechnical University Xi'an 710072 China. Department of Materials Science and Engineering City University of Hong Kong Hong Kong 999077 China. dangylei@cityu.edu.hk. Department of Materials Science and Engineering City University of Hong Kong Hong Kong 999077 China. The Institute of AI and Robotics Fudan University Shanghai 200433 China. Key Laboratory of Spectral Imaging Technology of Chinese Academy of Sciences Xi'an Institute of Optics and Precision Mechanics Chinese Academy of Sciences Xi'an 710119 China. Department of Electrical and Electronic Engineering Joint Appointment with School of Biomedical Sciences The University of Hong Kong Hong Kong 999077 China. State Key Laboratory of Robotics and System Harbin Institute of Technology Harbin Heilongjiang 150001 China. Ningbo Institute of Northwestern Polytechnical University College of Mechanical Engineering Northwestern Polytechnical University Xi'an 710072 China. yyt@***. Key Laboratory of Micro/Nano Systems for Aerospace (Ministry of Education) Northwestern Polytechnical University Xi'an 710072 China. yyt@***. Shaanxi Province Key Laboratory of Micro and Nano Electro-Mechanical Systems Northwestern Polytechnical University Xi'an 710072 China. yyt@***.

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Development of an assist upper limb exoskeleton for manual handling task

Development of an assist upper limb exoskeleton for manual h...

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2019 IEEE International Conference on robotics and Biomimetics, ROBIO 2019

作者： Yan, Zefeng Yi, Haoyuan Du, Zihao Huang, Tiantian Han, Bin Zhang, Lufeng Peng, Ansi Wu, Xinyu State Key Laboratory of Digital Manufacturing Equipment and Technology School of Mechanical Science and Engineering Huazhong University of Science and Technology China CAS Key Laboratory of Human-Manchine-Intelligence Synergic Systems Shenzhen Institutes of Advanced Technology Chinese Academy of Science Guangdong Provincial Key Lab of Robotics and Intelligent System Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences China

ISBN: (纸本)9781728163215

In this paper we describe the construction of a wearable upper arm exoskeleton to provide support for industrial workers who engaged in repetitive handling tasks and patients who full or partial loss of function in their upper limb due to accident injuries, spinal cord and strokes. We use flexible rope driven by a motor to realize the shoulder and elbow joints linkage, use ball screw to realize the self-locking in any position to providing assist for users. This novel design not only saves energy but also make the whole system portable. The total weight of the prototype is only 2 kg. The exoskeleton is connected upper limb with 3 bandages, and users take about 30 seconds to put it on and 20 seconds to put the exoskeleton off without any help. The PD adaptive control method is applied to the proposed exoskeleton to track expected trajectories. Five healthy people participated in data acquisition. Upper limb muscle integrated electromyography (IEMG) of the deltoid muscle(DM), the biceps femoris muscle (BFW), the femoral muscle (FM), the femoral wrist flexor (FWF) were compared in continuous handling for four different loads (0, 1.5, 3, 4.5kg). The average assistance efficiency were 39.1%, 41.5%, 36.5% and 40.6% for the DM, BFM, FM and FWF respectively. The experimental data show that the upper limb exoskeleton can provide assist for workers and protect their upper limbs injuries in long-term handling task. © 2019 IEEE.

关键词： Muscle

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A roadmap for AI in robotics

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Nature Machine Intelligence 2025年 1-7页

作者： Aude Billard Alin Albu-Schaeffer Michael Beetz Wolfram Burgard Peter Corke Matei Ciocarlie Ravinder Dahiya Danica Kragic Ken Goldberg Yukie Nagai Davide Scaramuzza Learning Algorithms and Systems Laboratory (LASA) École Polytechnique Fédérale de Lausanne (EPFL) Lausanne Switzerland Institute of Robotics and Mechatronics DLR-German Aerospace Center/Department of Informatics Technical University of Munich Munich Germany Institute for Artificial Intelligence Computer Science Department University of Bremen Bremen Germany Department of Engineering University of Technology Nuremberg Nuremberg Germany Center for Robotics Queensland University of Technology Brisbane Queensland Australia Columbia University New York City NY USA Northeastern University Boston MA USA School of Computer Science and Communication Royal Institute of Technology Stockholm Sweden University of California Berkeley Berkeley CA USA International Research Center for Neurointelligence The University of Tokyo Tokyo Japan Robotics and Perception Group University of Zurich Zurich Switzerland

There is growing excitement about the potential of leveraging artificial intelligence (AI) to tackle some of the outstanding barriers to the full deployment of robots in daily lives. However, action and sensing in the physical world pose greater and different challenges for AI than analysing data in isolation and it is important to reflect on which AI approaches are most likely to be successfully applied to robots. Questions to address, among others, are how AI models can be adapted to specific robot designs, tasks and environments. This Perspective offers an assessment of what AI has achieved for robotics since the 1990s and proposes a research roadmap with challenges and promises. These range from keeping up-to-date large datasets, representatives of a diversity of tasks that robots may have to perform, and of environments they may encounter, to designing AI algorithms tailored specifically to robotics problems but generic enough to apply to a wide range of applications and transfer easily to a variety of robotic platforms. For robots to collaborate effectively with humans, they must predict human behaviour without relying on bias-based profiling. Explainability and transparency in AI-driven robot control are essential for building trust, preventing misuse and attributing responsibility in accidents. We close with describing what are, in our view, primary long-term challenges, namely, designing robots capable of lifelong learning, and guaranteeing safe deployment and usage, as well as sustainable development.

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