Objective Bacillus strains are well known for their natural bioactive products that have antimicrobial and/or anti-cancer *** of Bacillus’structurally unique metabolites can combat human diseases,including ***,becaus...
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Objective Bacillus strains are well known for their natural bioactive products that have antimicrobial and/or anti-cancer *** of Bacillus’structurally unique metabolites can combat human diseases,including ***,because Bacillus’metabolites are so abundant,few have been studied extensively enough to fully characterize their chemical constitutions and biological *** In this study,we focused on the isolation and purification of a new Bacillus strain,and determined the effects of its metabolites on bacteria and cancer *** study focused on a new strain of Bacillus isolated from deer *** on BLAST results,this isolate belongs to Bacillus subtilis,and therefore we named the strain Bacillus subtilis *** red assay was used to test the cellulase *** inhibition zone was measured to test the antimicrobial ***-8,wound healing and flow cytometry were used to test the anti-cancer *** Metabolites from Bacillus subtilis NC16 have both antimicrobial and anti-cancer *** can both suppress the growth of Trichoderma vride and Staphylococcus aureus,and inhibit the proliferation and promote the apoptosis of non-small cell lung cancer cell *** Our results suggest that Bacillus subtilis NC16 can not only degrade cellulose,but its metabolites may be sources of antibiotics and anti-cancer drugs.
*** Wang(王德宝)was bom on May 7th,1918,in Taixing,Jiangsu Province,*** the age of 18,he was admitted to the Agricultural Chemistry Department of the National Central University,and graduated in *** the summer of 1943...
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*** Wang(王德宝)was bom on May 7th,1918,in Taixing,Jiangsu Province,*** the age of 18,he was admitted to the Agricultural Chemistry Department of the National Central University,and graduated in *** the summer of 1943,*** worked in the Department of Biochemistry,School of Biological Medicine,under the supervision of *** ***(Zhang,2020).At that time,he had a dream to contribute to the development of his motherland,which inspired him to study aboard.
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