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arXiv 2021年

作者： Reinke, Annika Tizabi, Minu D. Sudre, Carole H. Eisenmann, Matthias Rädsch, Tim Baumgartner, Michael Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Bankhead, Peter Benis, Arriel Blaschko, Matthew Buettner, Florian Cardoso, M. Jorge Chen, Jianxu Cheplygina, Veronika Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Engelhardt, Sandy Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hamprecht, Fred Hashimoto, Daniel A. Heckmann-Nötzel, Doreen Hirsch, Peter Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kavur, A. Emre Kenngott, Hannes Kleesiek, Jens Kleppe, Andreas Koehler, Sven Kofler, Florian Kopp-Schneider, Annette Kooi, Thijs Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moher, David Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Noyan, M. Alican Petersen, Jens Polat, Gorkem Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Rieke, Nicola Riegler, Michael A. Rivaz, Hassan Saez-Rodriguez, Julio Sánchez, Clara I. Schroeter, Julien Saha, Anindo Selver, M. Alper Sharan, Lalith Shetty, Shravya Smeden, Maarten V.A.N. Stieltjes, Bram Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben V.A.N. Varoquaux, Gaël Wiesenfarth, Manuel Yaniv, Ziv R. Jäger, Paul Maier-Hein, Lena Division of Intelligent Medical Systems and HI Helmholtz Imaging Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Intelligent Medical Systems Heidelberg Germany NCT Heidelberg DKFZ University Medical Center Heidelberg Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Division of Medical Image Computing Heidelberg Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Institute of Genetics and Cancer University of Edinburgh Edinburgh United Kingdom Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Kasteelpark Arenberg 10 - box 2441 Leuven3001 Belgium Frankfurt/Mainz DKFZ UCT Frankfurt-Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany Frankfurt Cancer Insititute Germany Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for St

While the importance of automatic image analysis is continuously increasing, recent meta-research revealed major flaws with respect to algorithm validation. Performance metrics are particularly key for meaningful, objective, and transparent performance assessment and validation of the used automatic algorithms, but relatively little attention has been given to the practical pitfalls when using specific metrics for a given image analysis task. These are typically related to (1) the disregard of inherent metric properties, such as the behaviour in the presence of class imbalance or small target structures, (2) the disregard of inherent data set properties, such as the non-independence of the test cases, and (3) the disregard of the actual biomedical domain interest that the metrics should reflect. This living dynamically document has the purpose to illustrate important limitations of performance metrics commonly applied in the field of image analysis. In this context, it focuses on biomedical image analysis problems that can be phrased as image-level classification, semantic segmentation, instance segmentation, or object detection task. The current version is based on a Delphi process on metrics conducted by an international consortium of image analysis experts from more than 60 institutions worldwide. © 2021, CC BY.

关键词： Medical imaging

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Design and Performance Evaluation of a Novel Vascular Interventional Surgery Robot

Design and Performance Evaluation of a Novel Vascular Interv...

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IEEE International Conference on robotics and Biomimetics

作者： Long Li Zhihui Huang Yingzhong Tian Wenbing Wang Wei Chen Zexi Li Fengfeng Xi School of Mechatronic Engineering and Automation Shanghai Key Laboratory of Intelligent Manufacturing and Robotics Shanghai China Mechanical and Electrical School of Shenzhen Polytechnic Shenzhen China Department of Mechanical Ryerson University Toronto ON Canada

ISBN: (纸本)9781728103785;9781728103778

In this paper, aiming at the problems existing in the vascular interventional surgery and the current research status, a vascular interventional surgery robot is designed by utilizing the master-slave control system. First, from the perspective of ergonomics, we design a master manipulator. It allows doctor to operate the medical catheter or guidewire directly during the operation. And then based on the same concept, we design a slave manipulator. It can reproduce the doctor's hand movements and ensure that the medical catheter or guidewire can reach the lesion smoothly in the blood vessels. Finally, the precision of the robot system is verified from the two dimensions of displacement and angle at different master-control ratios. Final results show that the whole interventional surgical robot system can meet the clinical requirements.

关键词： Manipulators Surgery Conferences Biomimetics

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A Robust Visual SLAM System Based on RGB-D Camera Used in Various Indoor Scenes

A Robust Visual SLAM System Based on RGB-D Camera Used in Va...

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IEEE International Conference on robotics and Biomimetics

作者： Long Li Angsong Li Yingzhong Tian Wenbin Wang Wei Chen Yining Fan Fengfeng Xi School of Mechatronic Engineering and Automation Shanghai Key Laboratory of Intelligent Manufacturing and Robotics Shanghai China Mechanical and Electrical School of Shenzhen Polytechnic Shenzhen China Department of Mechanical Aerospace and Industrial Engineering Ryerson University Toronto ON Canada

ISBN: (纸本)9781728103785;9781728103778

Generally speaking, visual SLAM systems just based on point features have poor robustness in low-textured scenes, which limits their application. To improve the robustness and accuracy of simultaneous location and mapping in various environments, a multi-scene adaptive visual SLAM system based on RGB-D camera is proposed. We not only use point features in our system, but also introduce line features that are abundant indoors. They are less sensitive to lighting variation and more stable than point features in low-textured scenes. The SLAM system combining point features and line features contains several parts: visual odometry, local mapping, loop closing, full BA and mapping. The experimental results on datasets demonstrate that the performance of our proposed SLAM system is better than state-of-the-art point-based method in various indoor scenes.

关键词： Bundle adjustment Urban areas Conferences Biomimetics Feature detection Feature extraction

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Remaining Useful Battery Life Prediction for UAVs based on Machine Learning

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IFAC-PapersOnLine 2017年第1期50卷 4727-4732页

作者： Mansouri S.S. Karvelis P. Georgoulas G. Nikolakopoulos G. Robotics Group Control Engineering Division of the Department of Computer Electrical and Space Engineering Luleå University of Technology Luleå SE-97187 Sweden Laboratory of Knowledge and Intelligent Computing Department of Computer Engineering Technological Educational Institute of Epirus Arta Greece

Unmanned Aerial Vehicles are becoming part of many industrial applications. The advancements in battery technologies played a crucial part for this trend. However, no matter what the advancements are, all batteries have a fixed capacity and after some time drain out. In order to extend the flying time window, the prediction of the time that the battery will no longer be able to support a flying condition is crucial. This in fact can be cast as a standard Remaining Useful Life prognostic problem, similarly encountered in many fields. In this article, the problem of Remaining Useful Life estimation of a battery, under different flight conditions, is tackled using four machine learning techniques: a linear sparse model, a variant of support vector regression, a multilayer perceptron and an advanced tree based algorithm. The efficiency of the overall proposed machine learning techniques, in the field of batteries prognostics, is evaluated based on multiple experimental data from different flight conditions. © 2017

关键词： Battery Machine Learning Prediction Remaining Useful Life UAVs

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An invisible DWT watermarking algorithm using noise removal with application to dermoscopic images

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Journal of Physics: Conference Series 2021年第1期1730卷

作者： S Moldovanu F A (Damian) Michis L Moraru Dunarea de Jos University of Galati Department of Computer Science and Information Technology Faculty of Automation Computers Sciences Electronics and Electrical Engineering 2 Stiintei Street RO-800210 Galati Romania Dunarea de Jos University of Galati Modelling & Simulation Laboratory Galati Romania Dunarea de Jos University of Galati Faculty of Science and Environment 111 Domneasca Street RO-800201 Galati Romania Department of Chemistry Physics and Environment Faculty of Sciences and Environment Dunarea de Jos University of Galati 47 Domneasca Street 800008 Galati Romania

A new approach for the digital watermarking process is proposed to be part of the pre-processing stage of a computer-aided diagnosis system. We propose to embed a denoised image acting as the watermark image in the original host image with the final goal of improving the quality of demoscopic images for further image processing operation related to CAD. The proposed algorithm uses Discrete Wavelet Transform (DWT) corroborated with some basic properties of Human Visual System such as Contrast Sensitive Function (CSF) and Noise Visibility Function (NVF) with the goal of correlating the texture properties and noise. This approach hides the watermark (i.e. denoised version of the host image) in high-pass subbands that are focused on image features. The main concern is to evaluate the distortion produced to the host image by watermarking and an objective quality measure function, i.e. Weighted Peak Signal-to-Noise Ratio (WPSNR), is used to evaluate the existing differences between the original and watermarked images. The proposed approach is tested using the available skin lesion images from the digital image archive of the department of Dermatology of the University Medical Center Groningen. The experiment results show the improved performance of the proposed scheme against a 3 × 3 median filtering attack in comparison with the a 5 × 5 median filtering attack.

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Joint learning of discriminative low-dimensional image representations based on dictionary learning and two-layer orthogonal projections

arXiv

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arXiv 2019年

作者： Wei, Xian Shen, Hao Li, Yuanxiang Tang, Xuan Jin, Bo Zhao, Lijun Murphey, Yi Lu Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences China Technical University of Munich Germany and fortiss GmbH Munich Germany Shanghai Key Lab for Trustworthy Computing School of Computer Science and Software Engineering East China Normal University China School of Aeronautics & Astronautics Shanghai Jiao Tong University Shanghai200240 China State Key Laboratory of Robotics and System Harbin Institute of Technology Harbin150006 China Department of Electrical and Computer Engineering University of Michigan-Dearborn DearbornMI48128 United States

This work investigates the problem of efficiently learning discriminative low-dimensional representations of multi-class large-scale image objects. We propose a generic deep learning approach by taking advantages of Convolutional Neural Networks (CNN), sparse dictionary learning, and orthogonal projections. CNN is not only powerful on feature extraction, but also robust to spatial variance and changes. Sparse dictionary learning is well known for disentangling nonlinear underlying discriminative factors in data. The orthogonal projection is a notable efficient tool to project multi-class data onto low dimensional discriminative subspace. The proposed procedure can be summarized as follows. At first, a CNN is employed to extract high-dimensional (HD) preliminary convolutional features. Secondly, to avoid the high computational cost of direct sparse coding on HD CNN features, we present to learn sparse representation (SR) in an orthogonal projected space over a task-driven sparsifying dictionary. We then exploit the discriminative projection on SR. The whole learning process is treated as a joint optimization problem of trace quotient maximization, which involves the CNN parameters, the orthogonal projection on CNN features, the dictionary and the discriminative projection on sparse codes. The related cost function is well defined on product manifold of the Stiefel manifold, the Oblique manifold, and the Grassmann manifold. It is optimized via a geometrical stochastic gradient descent algorithm. Finally, the quality of dictionary and projections learned by the proposed approach is further investigated in terms of image classification. The experimental results show that the approach can achieve a strongly competitive performance with state-of-the-art image classification methods. Copyright © 2019, The Authors. All rights reserved.

关键词： Convolution

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Robust medical instrument segmentation challenge 2019

arXiv

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arXiv 2020年

作者： Roβ, Tobias Reinke, Annika Full, Peter M. Wagner, Martin Kenngott, Hannes Apitz, Martin Hempe, Hellena Filimon, Diana Mindroc Scholz, Patrick Tran, Thuy Nuong Bruno, Pierangela Arbelaéz, Pablo Bian, Gui-Bin Bodenstedt, Sebastian Bolmgren, Jon Lindström Bravo-Sánchez, Laura Chen, Hua-Bin González, Cristina Guo, Dong Halvorsen, Pål Heng, Pheng-Ann Hosgor, Enes Hou, Zeng-Guang Isensee, Fabian Jha, Debesh Jiang, Tingting Kirtac, Kadir Jin, Yueming Kletz, Sabrina Leger, Stefan Li, Zhixuan Maier-Hein, Klaus H. Ni, Zhen-Liang Riegler, Michael A. Schoeffmann, Klaus Shi, Ruohua Speidel, Stefanie Stenze, Michael Twick, Isabell Wang, Gutai Wang, Jiacheng Wang, Liansheng Wang, Lu Zhang, Yujie Zhou, Yan-Jie Zhu, Lei Wiesenfarth, Manuel Kopp-Schneider, Annette Müller-Stich, Beat P. Maier-Hein, Lena Heidelberg Germany University of Heidelberg Germany Heidelberg Germany Department of General Heidelberg University Hospital Visceral and Transplant Surgery Heidelberg Germany caresyntax Berlin Germany University of Chinese Academy Sciences Beijing China State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences Beijing China SimulaMet Oslo Norway Tromsø Norway Oslo Norway School of Mechanical and Electrical Engineering University of Electronic Science and Technology of China Chengdu China Partner Site Dresden Heidelberg Germany Faculty of Medicine and University Hospital Carl Gustav Carus Technische Universität Dresden Dresden Germany Dresden Germany Universidad de Los Andes Bogotá Colombia Peking University Peking China Department of Computer Science School of Informatics Xiamen University Xiamen China Department of Computer Science and Engineering Chinese University of Hong Kong Hong Kong German Cancer Research Center Division of Biostatistics Heidelberg Germany Institute of Information Technology Klagenfurt University Austria

Intraoperative tracking of laparoscopic instruments is often a prerequisite for computer and roboticassisted interventions. While numerous methods for detecting, segmenting and tracking of medical instruments based on endoscopic video images have been proposed in the literature, key limitations remain to be addressed: Firstly, robustness, that is, the reliable performance of state-of-the-art methods when run on challenging images (e.g. in the presence of blood, smoke or motion artifacts). Secondly, generalization;algorithms trained for a specific intervention in a specific hospital should generalize to other interventions or institutions. In an effort to promote solutions for these limitations, we organized the Robust Medical Instrument Segmentation (ROBUST-MIS) challenge as an international benchmarking competition with a specific focus on the robustness and generalization capabilities of algorithms. For the first time in the field of endoscopic image processing, our challenge included a task on binary segmentation and also addressed multi-instance detection and segmentation. The challenge was based on a surgical data set comprising 10,040 annotated images acquired from a total of 30 surgical procedures from three different types of surgery. The validation of the competing methods for the three tasks (binary segmentation, multi-instance detection and multi-instance segmentation) was performed in three different stages with an increasing domain gap between the training and the test data. The results confirm the initial hypothesis, namely that algorithm performance degrades with an increasing domain gap. While the average detection and segmentation quality of the best-performing algorithms is high, future research should concentrate on detection and segmentation of small, crossing, moving and transparent instrument(s) (parts). Copyright © 2020, The Authors. All rights reserved.

关键词： Endoscopy

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Conditions for Global Asymptotic Stabilizability of the Double Integrator System with Output Saturation

Conditions for Global Asymptotic Stabilizability of the Doub...

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第37届中国控制会议

作者： Yuanlong Li Zongli Lin Department of Automation Shanghai Jiao Tong Universityand Key Laboratory of System Control and Information Processing of Ministry of Education Charles L.Brown Department of Electrical and Computer Engineering University of Virginia

In this paper we revisit the problem of global asymptotic stabilization of the double integrator system subject to output *** first observe that the double integrator system cannot be asymptotically stabilized by linear static output *** then establish that there exist linear dynamic output feedback laws that globally asymptotically stabilize the double integrator system subject to output *** determination of the linear output feedback laws is presented in the form of an *** results illustrate that the linear dynamic output feedback laws have the ability to achieve global asymptotic stabilization of the double integrator system subject to output saturation.

关键词： Double integrator Output saturation Global asymptotic stabilization

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Learn2Reg: comprehensive multi-task medical image registration challenge, dataset and evaluation in the era of deep learning

arXiv

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arXiv 2021年

作者： Hering, Alessa Hansen, Lasse Mok, Tony C.W. Chung, Albert C.S. Siebert, Hanna Häger, Stephanie Lange, Annkristin Kuckertz, Sven Heldmann, Stefan Shao, Wei Vesal, Sulaiman Rusu, Mirabela Sonn, Geoffrey Estienne, Théo Vakalopoulou, Maria Han, Luyi Huang, Yunzhi Yap, Pew-Thian Brudfors, Mikael Balbastre, Yaël Joutard, Samuel Modat, Marc Lifshitz, Gal Raviv, Dan Lv, Jinxin Li, Qiang Jaouen, Vincent Visvikis, Dimitris Fourcade, Constance Rubeaux, Mathieu Pan, Wentao Xu, Zhe Jian, Bailiang De Benetti, Francesca Wodzinski, Marek Gunnarsson, Niklas Sjölund, Jens Grzech, Daniel Qiu, Huaqi Li, Zeju Thorley, Alexander Duan, Jinming Großbröhmer, Christoph Hoopes, Andrew Reinertsen, Ingerid Xiao, Yiming Landman, Bennett Huo, Yuankai Murphy, Keelin Lessmann, Nikolas van Ginneken, Bram Dalca, Adrian V. Heinrich, Mattias P. Institute of Medical Informatics Universität zu Lübeck Ratzeburger Allee 160 Lübeck23562 Germany Fraunhofer MEVIS Institute for Digital Medicine Lübeck23562 Germany Department of Radiology and Nuclear Medicine Radboud University Medical Center GA Nijmegen6525 Netherlands The Institute of Medical Informatics Universität zu Lübeck Lübeck23562 Germany The Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong The Fraunhofer MEVIS Institute for Digital Medicine Lübeck23562 Germany The Department of Radiology Stanford University StanfordCA94305 United States The Department of Urology Stanford University StanfordCA94305 United States The Université Paris-Saclay CentraleSupélec Mathématiques et Informatique pour la Complexité et les Systèmes Inria Saclay Gif-sur-Yvette 91190 France Université Paris-Saclay Institut Gustave Roussy Inserm Radiothérapie Moléculaire et Innovation Thérapeutique Villejuif94800 France The Université Paris-Saclay CentraleSupélec Mathématiques et Informatique pour la Complexité et les Systèmes Inria Saclay Gif-sur-Yvette91190 France The Department of Radiology and Nuclear Medicine Radboud University Medical Center Nijmegen6525 GA Netherlands The School of Automation Nanjing University of Information Science and Technology Nanjing210044 China The School of Biomedical Engineering and Imaging Sciences King’s College London London United Kingdom The Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital United States Harvard Medical School Boston United States The King’s College London United Kingdom The Tel Aviv University The Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology Hubei Wuhan430074 China MoE Key Laboratory for Biomedical Photonics Collaborative Innovation Center for Biomedical Engineering School of Engineering Sciences Huazhong University of Sci

Image registration is a fundamental medical image analysis task, and a wide variety of approaches have been proposed. However, only a few studies have comprehensively compared medical image registration approaches on a wide range of clinically relevant tasks. This limits the development of registration methods, the adoption of research advances into practice, and a fair benchmark across competing approaches. The Learn2Reg challenge addresses these limitations by providing a multi-task medical image registration data set for comprehensive characterisation of deformable registration algorithms. A continuous evaluation will be possible at https://***. Learn2Reg covers a wide range of anatomies (brain, abdomen, and thorax), modalities (ultrasound, CT, MR), availability of annotations, as well as intra- and inter-patient registration evaluation. We established an easily accessible framework for training and validation of 3D registration methods, which enabled the compilation of results of over 65 individual method submissions from more than 20 unique teams. We used a complementary set of metrics, including robustness, accuracy, plausibility, and runtime, enabling unique insight into the current state-of-the-art of medical image registration. This paper describes datasets, tasks, evaluation methods and results of the challenge, as well as results of further analysis of transferability to new datasets, the importance of label supervision, and resulting bias. While no single approach worked best across all tasks, many methodological aspects could be identified that push the performance of medical image registration to new state-of-the-art performance. Furthermore, we demystified the common belief that conventional registration methods have to be much slower than deep-learning-based methods. © 2021, CC BY.

关键词： Image registration

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Two-Layer Distributed Formation-Containment Control of Multiple Euler-Lagrange Systems by Output Feedback

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IEEE Transactions on Cybernetics 2018年第2期49卷 675-687页

作者： Li, Dongyu Zhang, Wei He, Wei Li, Chuanjiang Ge, Shuzhi Sam Department of Control Science and Engineering Harbin Institute of Technology Harbin150001 China Shanghai Institute of Satellite Engineering Shanghai Key Laboratory of Deep Space Exploration Technology Shanghai201109 China School of Automation and Electrical Engineering University of Science and Technology Beijing Beijing100083 China Department of Electrical and Computer Engineering National University of Singapore Singapore117576 Singapore

This paper addresses the distributed formation-containment (DFC) problem for multiple Euler-Lagrange systems with model uncertainties via output feedback in both constant and time-varying formation cases. First, a novel definition of the DFC problem is proposed using a two-layer framework. Since only parts of the followers can acquire the states of the dynamic leader, we design a distributed finite-time sliding-mode estimator to obtain accurate estimations of the desired position and velocity for each agent. Next, to deal with the absence of velocity sensors, we propose two DFC control laws combined with the high-gain observer for the leaders and the followers, respectively, while the time-varying formation in the first layer and the leader-based containment in the second layer can be achieved. Further, the adaptive neural networks are applied to deal with the model uncertainties due to their superior approximation capability. The uniform ultimate boundedness of all the state errors can be guaranteed by Lyapunov stability theory. In addition, a unified framework is given which can be transformed to four other basic distributed problems. Finally, simulation examples are presented to illustrate the feasibility of the theoretical results. © 2013 IEEE.

关键词： Lagrange multipliers

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