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Association between Electroencephalographic microstates abnormalities and cognitive dysfunction in drug-naive MDD

Brain Research 2025年 1860卷 149660-149660页

作者： Qin, Qin Liu, Xinyu Wang, Bin Wang, Xin Liang, Sixiang Chen, Chao Li, Meijia Han, Chuanliang Zhao, Xixi National Clinical Research Center for Mental Disorders & National Center for Mental Disorders Beijing Key Laboratory of Mental Disorders Beijing Anding Hospital Capital Medical University Beijing China Advanced Innovation Center for Human Brain Protection Capital Medical University Beijing China Department of Clinical Psychology Shandong Provincial Hospital affiliated to Shandong First Medical University Shandong China Key Laboratory of Complex System Control Theory and Application Tianjin University of Technology Tianjin 300384 China Faculty of Psychology and Center for Neuroscience Vrije Universiteit Brussel Brussels 1050 Belgium School of Biomedical Sciences and The Gerald Choa Neuroscience Institute The Chinese University of Hong Kong Hong Kong SAR China

Objectives: This study aims to investigate the link between Electroencephalography (EEG) microstate anomalies and cognitive impairments in individuals with drug-naive Major depressive disorder (MDD). Methods: We recruited 29 patients with drug-naive MDD and 30 healthy controls. The Hamilton Depression Rating Scale (HDRS-17) measured symptom severity, the MATRICS Consensus Cognitive Battery (MCCB) assessed neurocognitive function, and resting-state EEG data were collected using 64 scalp electrodes. Analysis of EEG microstates was conducted via the Microstate Analysis plugin for EEGLAB. Results: MDD group had lower scores in six neurocognitive MCCB domains. For EEG microstates, four similar ones (A − D) were found in both groups. Notably, microstate C duration was lower in MDD group (t = 4.549, P < 0.001), microstate D occurrence (t = 2.258, P = 0.028) and proportion (t = 3.733, P < 0.001) were lower in MDD group. There were significant differences in all 4 microstate transition probabilities between groups. For example, A − B, B − A etc. transitions were higher in MDD, while A − C, A − D etc. were lower. The proportion of microstate D was found positively correlated with Speed of processing (SOP) score (r = 0.499, df = 26, P = 0.007) and Working memory (WM) score (r = 0.451, df = 26, P = 0.016). The Occurrence of microstate D was found positively correlated with SOP score (r = 0.383, df = 26, P = 0.044) and WM score (r = 0.389, df = 26, P = 0.041). Conclusions: MDD patients show alterations in sub-second brain dynamics, characterized by a decreased proportion and occurrence of microstate D and shorter duration of microstate C, and significant shifts in microstate transition probabilities. These changes correlate with cognitive deficits across several domains, including processing speed and working memory. © 2025

关键词： Cognitive dysfunction Electroencephalographic microstates Major depressive disorder

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Plasma Power Effect on Crystallinity and Density of Peald-Aln Thin Films： Toward Increasing Dielectric Constant and Breakdown Electric Field

SSRN

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SSRN 2023年

作者： Zhang, Xiao-Ying Peng, Duan-Chen Yan, Jia-Hao Zhang, Zhi-Xuan Ruan, Yu-Jiao Zuo, Juan Xie, An Wu, Wan-Yu Wuu, Dong-Sing Huang, Chien-Jung Lai, Feng-Min Lien, Shui-Yang Zhu, Wen-Zhang Xiamen Key Laboratory of Development and Application for Advanced Semiconduc tor Coating Technology School of Opto-electronic and Communication Engineering Xiamen University of Technology Xiamen361024 China National Measurement and Testing Center for Flat Panel Display Industry Xiamen Institute of Measurement and Testing Xiamen361024 China School of Materials Science and Engineering Xiamen University of Technology Xiamen361024 China Department of Materials Science and Engineering National United University Miaoli36063 Taiwan Department of Applied Materials and Optoelectronic Engineering National Chi Nan University Nantou54561 Taiwan Department of Applied Physics National University of Kaohsiung Kaohsiung University Rd. Kaohsiung81148 Taiwan Department of Biomedical Engineering Da-Yeh University Changhua51591 Taiwan

Aluminum nitride (AlN) film is a promising material which is used in various fields. In this study, AlN films with different plasma powers were grown by remote plasma atomic layer deposition. Saturation experiments have been applied in the plasma power between 1000 and 3000 W. The influence of plasma power on preferential orientation, chemical, optical, and electrical properties of AlN films are investigated. AlN films displayed multiphase hexagonal wurtzite crystal structure with (002) preferential orientation for higher plasma power, while the predominant orientation shifted toward (100) at lower plasma power. The optical emission spectroscopy analyses show that NH and NH2 radicals conduce to the deposition of AlN films and H radicals selectively dissociate Al-OH bonds which were on AlN film surface and etch deposition films. AFM measurements show that the 1500 W prepared AlN film with smallest surface roughness may be related to the relatively smaller concomitant crystal grains of (100) and (002). X-ray photoelectron spectroscopy investigation presents that oxygen content decreases as the plasma power increases. The obtained maximum value of dielectric constant and breakdown electrical field of AlN film deposited at 3000 W is 8.23 and 5.42 MV/cm, respectively. © 2023, The Authors. All rights reserved.

关键词： Aluminum nitride

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Coupled Pacific Rim megadroughts contributed to the fall of the MingDynasty’s capital in 1644 CE

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Science Bulletin 2024年第19期69卷 3106-3114页

作者： Feng Chen Tao Wang Xiaoen Zhao Jan Esper Fredrik Charpentier Ljungqvist Ulf Büntgen Hans W.Linderholm David Meko Hongna Xu Weipeng Yue Shijie Wang Yujiang Yuan Jingyun Zheng Wei Pan Fidel Roig Martín Hadad Mao Hu Jiachang Wei Fahu Chen Yunnan Key Laboratory of International Rivers and Transboundary Eco-Security Institute of International Rivers and Eco-SecurityYunnan UniversityKunming 650504China Southwest United Graduate School Kunming 650504China Climate Change Research Center and Nansen-Zhu International Research Centre Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Department of Geography Johannes Gutenberg UniversityMainz 55099Germany Global Change Research Institute(CzechGlobe) Czech Academy of SciencesBrno 60300Czech Republic Department of History Stockholm UniversityStockholm 10691Sweden Bolin Centre for Climate Research Stockholm UniversityStockholm 10691Sweden Swedish Collegium for Advanced Study LinneanumUppsala 75238Sweden Department of Geography University of CambridgeCambridge CB23ENUK Department of Geography Faculty of ScienceMasaryk UniversityBrno 61137Czech Republic Swiss Federal Research Institute(WSL) Birmensdorf 8903Switzerland Regional Climate Group Department of Earth SciencesUniversity of GothenburgGothenburg 40530Sweden Laboratory of Tree-Ring Research University of ArizonaTucson AZ 85721USA Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC FEMD) Nanjing University of Information Science and TechnologyNanjing 210044China Key Laboratory of Tree-ring Physical and Chemical Research Institute of Desert MeteorologyChina Meteorological AdministrationUrumqi 830002China Key Laboratory of Land Surface Pattern and Simulation Institute of Geographical Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China Key Laboratory of Digital Human Technology R&D and Application of Yunnan Provincial Department of Education Yunnan UniversityKunming 650504China Laboratorio de Dendrocronología e Historia Ambiental IANIGLA-CCT CONICET-Universidad Nacional de CuyoMendoza 5500Argentina Hémera Centro de Observación de La Tierra Escuela de Ingeniería ForestalFacultad de CienciasUniversidad MayorHuechuraba 85

Historical documents provide evidence for regional droughts preceding the political turmoil and fall of Beijing in 1644 CE,when more than 20 million people died in northern China during the late Ming famine ***,the role climate and environmental changes may have played in this pivotal event in Chinese history remains ***,we provide tree-ring evidence of persistent megadroughts from1576 to 1593 CE and from 1628 to 1644 CE in northern China,which coincided with exceptionally cold summers just before the fall of *** analysis reveals that these regional hydroclimatic extremes are part of a series of megadroughts along the Pacific Rim,which not only impacted the ecology and society of monsoonal northern China,but likely also exacerbated external geopolitical and economic *** finding is corroborated by last millennium reanalysis data and numerical climate model simulations revealing internally driven Pacific sea surface temperature variations and the predominance of decadal scale La Ni?a-like conditions to be responsible for precipitation decreases over northern China,as well as extensive monsoon regions in the *** teleconnection patterns provide a mechanistic explanation for reoccurring drought spells during the late Ming Dynasty and the environmental framework fostering the fall of Beijing in 1644 CE,and the subsequent demise of the Ming Dynasty.

关键词： Paleoclimate Beijing Precipitation reconstruction Climate-society interactions Tree rings Ming Dynasty

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Superior Performance of ZnGaO Solar-Blind Photodetectors by Implementing TFT Structure and Tunable ZNO Cycle Ratio

SSRN

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SSRN 2024年

作者： Fan, Hui-Chen Wang, Chen Xu, Yi-Hong Fan, Teng-Min Huang, Pao-Hsun Ruan, Yu-Jiao Wu, Tingzhu Kuo, Hao-Chung Wuu, Dong-Sing Lai, Feng-Min Lien, Shui-Yang Xiamen Key Laboratory of Development and Application for Advanced Semiconductor Coating Technology School of Opto-Electronic and Communication Engineering Xiamen University of Technology Xiamen361024 China School of Ocean Information Engineering Jimei University Jimei District Fujian Xiamen361021 China National Measurement and Testing Center for Flat Panel Display Industry Xiamen Institute of Measurement and Testing Xiamen361024 China National Integrated Circuit Industry and Education Integration Innovation Platform Department of Electronic Science Xiamen University Xiamen361005 China Department of Photonics Graduate Institute of Electro-Optical Engineering College of Electrical and Computer Engineering National Yang Ming Chiao Tung University Hsinchu30010 Taiwan Department of Applied Materials and Optoelectronic Engineering National Chi Nan University Nantou54561 Taiwan Department of Biomedical Engineering Da-Yeh University Changhua51591 Taiwan

In this study, plasma enhanced atomic layer deposition was used to prepare ZnGaO thin films with different ZnO cycle ratios from 0% to 50%, which were employed to fabricate the MSM-type and TFT-type solar-blind photodetector. The properties of the films and the performance of the solar blind photodetector are greatly affected by the ZnO cycle ratio. Appropriate Zn doping content decreases the ratio of oxygen vacancies and Zn interstitials in Ga2O3, while excessive Zn doping degrades the quality of the film. Compared to MSM-type photodetector, an obviously improved performance of ZnGaO TFT-type photodetector has been observed due to its self-amplified photocurrent and the reduced dark current controlled by gate voltage. At a ZnO cycle ratio of 40%, a superior performance of TFT-type solar-blind photodetector with an ultra-low dark current ~4.5×10-13 A, an excellent light switching ratio ~2.2×107, and an outstandingly high sensitivity ~34.31 A/W has been obtained. These results demonstrate that the incorporation of Zn dopants can effectively modulate the performance of Ga2O3 TFT-type photodetector providing a great perspective for cost-effective and high-performance solar-blind PDs. © 2024, The Authors. All rights reserved.

关键词： Zinc oxide

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Publisher Correction: Fabrication of red-emitting perovskite LEDs by stabilizing their octahedral structure

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Nature 2024年第8020期631卷 E10页

作者： Lingmei Kong Yuqi Sun Bin Zhao Kangyu Ji Jie Feng Jianchao Dong Yuanzhi Wang Zirui Liu Shabnum Maqbool Yunguo Li Yingguo Yang Linjie Dai Wanhee Lee Changsoon Cho Samuel D Stranks Richard H Friend Ning Wang Neil C Greenham Xuyong Yang Key Laboratory of Advanced Display and System Applications of Ministry of Education Shanghai University Shanghai China. Cavendish Laboratory University of Cambridge Cambridge UK. College of Physics Jilin University Changchun China. Department of Chemical Engineering and Biotechnology University of Cambridge Cambridge UK. CAS Key Laboratory of Crust-Mantle Materials and Environments School of Earth and Space Sciences University of Science and Technology of China Hefei China. Shanghai Synchrotron Radiation Facility (SSRF) Zhangjiang Lab Shanghai Advanced Research Institute Chinese Academy of Sciences Shanghai China. School of Microelectronics Fudan University Shanghai China. Department of Material Science and Engineering Pohang University of Science and Technology (POSTECH) Pohang Republic of Korea. Institute for Convergence Research and Education in Advanced Technology Yonsei University Seoul Republic of Korea. College of Physics Jilin University Changchun China. ningwang@***. Cavendish Laboratory University of Cambridge Cambridge UK. ncg11@cam.ac.uk. Key Laboratory of Advanced Display and System Applications of Ministry of Education Shanghai University Shanghai China. yangxy@***. Shanghai Engineering Research Center for Integrated Circuits and Advanced Display Materials Shanghai China. yangxy@***.

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AMOLED Encapsulation technology and Prospect

AMOLED Encapsulation Technology and Prospect

引用

International Conference on display technology, ICDT 2018

作者： Ao, Wei Li, Chunhong Wang, Yan Liu, Xiangchao Xin, Xiaogang Gao, Feng Peng, Chaochi Zhang, Jianhua Key Laboratory of Advanced Display and System Application Ministry of Education Shanghai University Shanghai200072 China

ISBN: (纸本)9781510867659

The flexible organic light emitting diodes (OLEDs) has attracted a lot of attention because of its very wide and promising application prospect. The flexible encapsulation is a most problem for mass production of flexible OLEDs since their sensitivity to water and oxygen. Traditional flexible encapsulation using plasma enhanced chemical vapor deposition (PECVD) film as the inorganic layer. However owing to the complicated pattern of sub-layer and particles, the poor step coverage of PECVD film results in bad encapsulation properties. Therefore the plasma enhanced atomic layer deposition (PEALD) is studied on account of its better step coverage and lower growth temperature. Firstly, the PECVD SiNx process has been researched to achieve the low water vapor transmission rate (WVTR) (WVTR*10-4g m-2day-1) and low stress ( © 2018 SID.

关键词： Plasma enhanced chemical vapor deposition

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Recent Advances in Triboelectric Nanogenerators: From Technological Progress to Commercial applications

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ACS Nano 2023年第12期17卷 11087-11219页

作者： Choi, Dongwhi Lee, Younghoon Lin, Zong-Hong Cho, Sumin Kim, Miso Ao, Chi Kit Soh, Siowling Sohn, Changwan Jeong, Chang Kyu Lee, Jeongwan Lee, Minbaek Lee, Seungah Ryu, Jungho Parashar, Parag Cho, Yujang Ahn, Jaewan Kim, Il-Doo Jiang, Feng Lee, Pooi See Khandelwal, Gaurav Kim, Sang-Jae Kim, Hyun Soo Song, Hyun-Cheol Kim, Minje Nah, Junghyo Kim, Wook Menge, Habtamu Gebeyehu Park, Yong Tae Xu, Wei Hao, Jianhua Park, Hyosik Lee, Ju-Hyuck Lee, Dong-Min Kim, Sang-Woo Park, Ji Young Zhang, Haixia Zi, Yunlong Guo, Ru Cheng, Jia Yang, Ze Xie, Yannan Lee, Sangmin Chung, Jihoon Oh, Il-Kwon Kim, Ji-Seok Cheng, Tinghai Gao, Qi Cheng, Gang Gu, Guangqin Shim, Minseob Jung, Jeehoon Yun, Changwoo Zhang, Chi Liu, Guoxu Chen, Yufeng Kim, Suhan Chen, Xiangyu Hu, Jun Pu, Xiong Guo, Zi Hao Wang, Xudong Chen, Jun Xiao, Xiao Xie, Xing Jarin, Mourin Zhang, Hulin Lai, Ying-Chih He, Tianyiyi Kim, Hakjeong Park, Inkyu Ahn, Junseong Huynh, Nghia Dinh Yang, Ya Wang, Zhong Lin Baik, Jeong Min Choi, Dukhyun Kyung Hee University Gyeonggi Yongin17104 Korea Republic of Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology 77 Massachusetts Avenue CambridgeMA02139 United States Department of Mechanical Engineering Soft Robotics Research Center Seoul National University Seoul08826 Korea Republic of Department of Mechanical Engineering Gachon University Seongnam13120 Korea Republic of Department of Biomedical Engineering National Taiwan University Taipei10617 Taiwan Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu30013 Taiwan School of Advanced Materials Science & Engineering Sungkyunkwan University Suwon16419 Korea Republic of Sungkyunkwan University 2066 Seobu-ro Gyeonggi Suwon16419 Korea Republic of Department of Chemical and Biomolecular Engineering National University of Singapore 4 Engineering Drive 4 117585 Singapore Division of Advanced Materials Engineering Jeonbuk National University 567 Baekje-daero Jeonbuk Jeonju54896 Korea Republic of Jeonbuk National University 567 Baekje-daero Jeonbuk Jeonju54896 Korea Republic of Department of Physics Inha University 100 Inha-ro Incheon22212 Korea Republic of School of Materials Science & Engineering Yeungnam University Gyeongbuk Gyeongsan38541 Korea Republic of 291 Daehak-ro Daejeon34141 Korea Republic of School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue 639798 Singapore Institute of Flexible Electronics Technology of Tsinghua Zhejiang Jiaxing314000 China Nanomaterials and System Lab Major of Mechatronics Engineering Faculty of Applied Energy System Jeju National University Jeju632-43 Korea Republic of School of Engineering University of Glasgow GlasgowG128QQ United Kingdom Seoul02792 Korea Republic of Department of Physics Inha University Incheon22212 Korea Republic of Suwon16419 Korea Republic of Department of

Serious climate changes and energy-related environmental problems are currently critical issues in the world. In order to reduce carbon emissions and save our environment, renewable energy harvesting technologies will serve as a key solution in the near future. Among them, triboelectric nanogenerators (TENGs), which is one of the most promising mechanical energy harvesters by means of contact electrification phenomenon, are explosively developing due to abundant wasting mechanical energy sources and a number of superior advantages in a wide availability and selection of materials, relatively simple device configurations, and low-cost processing. Significant experimental and theoretical efforts have been achieved toward understanding fundamental behaviors and a wide range of demonstrations since its report in 2012. As a result, considerable technological advancement has been exhibited and it advances the timeline of achievement in the proposed roadmap. Now, the technology has reached the stage of prototype development with verification of performance beyond the lab scale environment toward its commercialization. In this review, distinguished authors in the world worked together to summarize the state of the art in theory, materials, devices, systems, circuits, and applications in TENG fields. The great research achievements of researchers in this field around the world over the past decade are expected to play a major role in coming to fruition of unexpectedly accelerated technological advances over the next decade. © 2023 The Authors. Published by American Chemical Society

关键词： Nanogenerators

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Molecular tailoring towards two-dimensional organic crystals at the thickness limit

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Chinese Chemical Letters 2024年

作者： Zhilei Zhang Yanan Sun Xiaosong Shi Xiaozhe Yin Dawei Liu Erjing Wang Jie Liu Yuanyuan Hu Lang Jiang Beijing National Laboratory for Molecular Sciences Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China University of the Chinese Academy of Sciences Beijing 100049 China Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials Faculty of Materials Science and Engineering Hubei University Wuhan 430062 China Key Laboratory for Micro/Nano Optoelectronic Devices of Ministry of Education & International Science and Technology Innovation Cooperation Base for Advanced Display Technologies of Hunan Province School of Physics and Electronics Hunan University Changsha 410082 China

Advances in controllable growth of ultrathin two-dimensional molecular crystals (2DMCs) or even monolayer molecular crystals (MMCs) propelled their application in high-performance, high-sensitivity, low-contact-resistance optoelectronic devices. However, the rational molecular design strategies for materials prone to grow into ultrathin 2DMC or MMC have rarely been addressed. Here, systematically tailoring the π -conjugation and alkyl chain types of asymmetric anthracene derivatives, 2DMCs and even MMCs were obtained under the synergetic regulation of inter- and intralayer interactions. High-quality MMCs were obtained for SAP-C6 by traditional physical vapor transport technique (PVT), and corresponding organic field-effect transistors (OFETs) exhibited high mobility of 3.22 cm 2 V -1 s -1 . In addition, band-like charge transport with low activation energy was achieved by SAP-C6 MMC-OFETs. Furthermore, the SAP-C6 MMC-based device exhibits excellent thermal stability, retaining ∼70% of its initial performance at 140°C in air, which is the first report on the thermal stability of MMC devices. This research highlights the potential of alkyl-substituted asymmetric molecules as a design strategy to achieve ultrathin 2DMC or MMC growth, and improve the mobility and thermal stability in OFETs.

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Deep-Blue Electroluminescence of Perovskites with Reduced Dimensionality Achieved by Manipulating Adsorption-Energy Differences

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Angewandte Chemie 2022年第40期134卷

作者： Dr. Jianchao Dong Dr. Feifei Lu Dr. Dongyuan Han Dr. Jie Wang Dr. Ziang Zang Dr. Lingmei Kong Dr. Yu Zhang Dr. Xue Ma Dr. Jianheng Zhou Dr. Huiyu Ji Prof. Xuyong Yang Prof. Ning Wang Key Laboratory of Physics and Technology for Advanced Batteries of Ministry of Education College of Physics Jilin University Changchun 130012 P. R. China Key Laboratory of Advanced Display and System Applications of Ministry of Education Shanghai University 149 Yanchang Road Shanghai 200072 P. R. China

The lagging development of deep-blue perovskite light-emitting diodes (PeLEDs) heavily impedes their practical applications in full-color display due to the absence of spectrally stable emitters and the mismatch of carrier injection capacity. Herein, we report highly efficient deep-blue PeLEDs through a new chemical strategy that addresses the dilemma for simultaneously constant electroluminescence (EL) spectra and high-purify phase in reduced-dimensional perovskites. The success lies in the control of adsorption-energy differences between phenylbutylamine (PBA) and ethylamine (EA) interacting with perovskites, which facilitates narrow n -value distribution. This approach leads to an increased exciton binding energy and enhanced surface potential, hence improving radiative recombination. As a result, an external quantum efficiency of 4.62 % is achieved in PeLEDs with a stable EL peak at 457 nm, demonstrating the best reported result for deep-blue PeLEDs so far.

关键词： Adsorption Energy Deep-Blue Emission Perovskites Reduced Dimensionality

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Synthesis and properties of novel N,C,N terdentate skeleton based on 1,3-di(pyridin-2-yl)benzene moiety-new tricks for old dogs

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Chinese Chemical Letters 2019年第11期30卷 1951-1954页

作者： Shuai Tan Xiugang Wu Yanqiong Zheng Yafei Wang a Jiangsu Engineering Laboratory of Light-Electricity-Heat Energy-Converting Materials and Applications Jiangsu Key Laboratory of Environmentally Friendly Polymeric MaterialsJiangsu Collaboration Innovation Center of Photovoltaic Science and EngineeringSchool of Materials Science&EngineeringChangzhou UniversityChangzhou 213164China b College of Chemistry Key Lab of Environment-Friendly Chemistry and Application of the Ministry of EducationXiangtan UniversityXiangtan 411105China c Key Laboratory of Advanced Display and System Applications of Ministry of Education Shanghai UniversityShanghai 200072China

Utilization of intermolecular Friedel-Crafts and intramolecular condensation reaction,novel 1,3-di-(pyridine-2-yl)benzene(N,C,N terdentate)skeleton with electro-withdrawing group in 6'position of pyridyl and a cyclization between 6'position of pyridyl and 6 position of benzyl ring were firstly designed and *** structures of these novel N,C,N terdentate were confirmed by NMR,MS and X-ray single *** photophysical properties of these compounds were briefly explored.

关键词： 1,3-Di(pyridin-2-yl)benzene skeleton Platinum complex Synthesis Intramolecular cyclization

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