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Aortic Vessel Tree Segmentation for Cardiovascular Diseases Treatment: Status Quo

ACM Computing Surveys 1000年

作者： Yuan Jin Antonio Pepe Jianning Li Christina Gsaxner Yuxuan Chen Behrus Puladi Fen-hua Zhao Kelsey Pomykala Jens Kleesiek Alejandro Frangi Jan Egger Institute of Computer Graphics and Vision Graz University of Technology Graz Austria Research Centre for Frontier Fundamental Studies Zhejiang Lab Hangzhou China Institute of Computer Graphics and Vision Graz University of Technology Graz Austria Institute for Artificial Intelligence in Medicine Essen University Hospital (AöR) Essen Germany Zhejiang Laboratory of Philosophy and Social Sciences - Laboratory of Intelligent Society and Governance Zhejiang Lab Hangzhou China Institute of Medical Informatics RWTH Aachen University Aachen Germany Wenzhou Medical University Affiliated Dongyang Hospital Dongyang China Cancer Research Center Cologne Essen Essen Germany German Cancer Consortium Heidelberg Germany Christabel Pankhurst Institute The University of Manchester Manchester United Kingdom of Great Britain and Northern Ireland School of Health Sciences The University of Manchester Division of Informatics Imaging and Data Sciences Manchester United Kingdom of Great Britain and Northern Ireland The University of Manchester School of Computer Science Manchester United Kingdom of Great Britain and Northern Ireland Manchester University NHS Foundation Trust Manchester United Kingdom of Great Britain and Northern Ireland Insitute of Artificial Intelligence in Medicine Essen University Hospital (AöR) Essen Germany Computer Algorithms for Medicine Laboratory Graz Austria Cancer Research Center Cologne Essen (CCCE) Essen Germany

The aortic vessel tree, composed of the aorta and its branches, is crucial for blood supply to the body. Aortic diseases, such as aneurysms and dissections, can lead to life-threatening ruptures, often requiring open surgery. Therefore, patients commonly undergo treatment under constant monitoring, which requires regular inspections of the vessels through medical imaging techniques. Overlapping and comparing aortic vessel tree geometries from consecutive images allows for tracking changes in both the aorta and its branches. Manual reconstruction of the vessel tree is time-consuming and impractical in clinical settings. In contrast, automatic or semi-automatic segmentation algorithms can perform this task much faster, making them suitable for routine clinical use. This paper systematically reviews methods for the automatic and semi-automatic segmentation of the aortic vessel tree, concluding with a discussion on their clinical applicability, the current research landscape, and ongoing challenges.

关键词： Aorta Vessel Tree Machine Learning Deep Learning Segmentation Analysis Cardiovascular Disease Aneurysm Dissection Computed Tomography.

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The importance of transparency and reproducibility in artificial intelligence research

arXiv

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arXiv 2020年

作者： Haibe-Kains, Benjamin Adam, George Alexandru Hosny, Ahmed Khodakarami, Farnoosh Waldron, Levi Wang, Bo McIntosh, Chris Kundaje, Anshul Greene, Casey S. Hoffman, Michael M. Leek, Jeffrey T. Huber, Wolfgang Brazma, Alvis Pineau, Joelle Tibshirani, Robert Hastie, Trevor Ioannidis, John P.A. Quackenbush, John Aerts, Hugo J.W.L. Princess Margaret Cancer Centre University Health Network TorontoON Canada Department of Medical Biophysics University of Toronto TorontoON Canada Department of Computer Science University of Toronto TorontoON Canada Ontario Institute for Cancer Research TorontoON Canada Vector Institute for Artificial Intelligence TorontoON Canada Program Brigham and Women's Hospital Harvard Medical School BostonMA United States Radiation Oncology and Radiology Dana-Farber Cancer Institute Brigham and Women's Department of Epidemiology and Biostatistics Institute for Implementation Science in Population Health CUNY Graduate School of Public Health and Health Policy New YorkNY United States Peter Munk Cardiac Centre University Health Network TorontoON Canada Hospital Harvard Medical School BostonMA United States Department of Genetics Stanford University School of Medicine StanfordCA United States Dept. of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Childhood Cancer Data Lab Alex's Lemonade Stand Foundation PhiladelphiaPA United States Department of Biostatistics Johns Hopkins Bloomberg School of Public Health BaltimoreMD United States European Molecular Biology Laboratory Genome Biology Unit Heidelberg Germany European Molecular Biology Laboratory European Bioinformatics Institute EMBL-EBI Hinxton United Kingdom McGill University MontrealQC Canada Montreal Institute for Learning Algorithms QC Canada StanfordCA United States Department of Biomedical Data Science Stanford University School of Medicine StanfordCA United States Departments of Medicine of Health Research and Policy and of Biomedical Data Science Stanford University School of Medicine StanfordCA United States Department of Statistics Stanford University School of Humanities and Sciences StanfordCA United States Department of Biostatistics Harvard T.H Chan School of Public Health BostonMA Un

In their study, McKinney et al. showed the high potential of artificial intelligence for breast cancer screening. However, the lack of detailed methods and computer code undermines its scientific value. We identify obstacles hindering transparent and reproducible AI research as faced by McKinney et al and provide solutions with implications for the broader field. Copyright © 2020, The Authors. All rights reserved.

关键词： Artificial intelligence

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Ten new insights in climate science 2024

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One Earth 2025年

作者： Schaeffer, Roberto Schipper, E. Lisa F. Ospina, Daniel Mirazo, Paula Alencar, Ane Anvari, Mehrnaz Artaxo, Paulo Biresselioglu, Mehmet Efe Blome, Tanja Boeckmann, Melanie Brink, Ebba Broadgate, Wendy Bustamante, Mercedes Cai, Wenju Canadell, Josep G. Cardinale, Roberto Chidichimo, Maria Paz Ditlevsen, Peter Eicker, Ursula Feron, Sarah Fikru, Mahelet G. Fuss, Sabine Gaye, Amadou T. Gustafsson, Örjan Harring, Niklas He, Cheng Hebden, Sophie Heilemann, Adrian Hirota, Marina Janardhanan, Nandakumar Juhola, Sirkku Jung, Tae Yong Kejun, Jiang Kilkiș, Şiir Kumarasinghe, Nilushi Lapola, David Lee, June-Yi Levis, Carolina Lusambili, Adelaide Maasakkers, Joannes D. MacIntosh, Claire Mahmood, Jemilah Mankin, Justin S. Marchegiani, Pía Martin, Maria Mukherji, Aditi Muñoz-Erickson, Tischa A. Niazi, Zeenat Nyangon, Joseph Pandipati, Santosh Perera, Amarasinghage T.D. Persad, Geeta Persson, Åsa Redman, Aaron Riipinen, Ilona Rockström, Johan Roffe, Sarah Roy, Joyashree Sakschewski, Boris Samset, Bjørn H. Schlosser, Peter Sharifi, Ayyoob Shih, Wan-Yu Sioen, Giles B. Sokona, Youba Stammer, Detlef Suk, Sunhee Thiam, Djiby Thompson, Vikki Tullos, Erin van Westen, René M. Vargas Falla, Ana Maria Vecellio, Daniel J. Worden, John Wu, Henry C. Xu, Chi Yang, Yang Zachariah, Mariam Zhang, Zhen Ziervogel, Gina Federal University of Rio de Janeiro Rio de Janeiro Brazil University of Bonn Bonn Germany Future Earth Secretariat Stockholm Sweden Arizona State University Tempe AZ United States Amazon Environmental Research Institute (IPAM) Brasilia Brazil Fraunhofer Institute for Algorithms and Scientific Computing SCAI St. Augustin Germany Potsdam Institute for Climate Impact Research (PIK) Potsdam Germany University of São Paulo São Paulo Brazil İzmir University of Economics İzmir Turkey Climate Service Center Germany (GERICS) Helmholtz-Zentrum Hereon Hamburg Germany University of Bremen Bremen Germany Lund University Lund Sweden University of Brasilia Brasilia Brazil Ocean University of China Qingdao China Xiamen University Xiamen China Commonwealth Scientific and Industrial Research Organisation (CSIRO) Environment Canberra ACT Australia University College London London United Kingdom National Scientific and Technical Research Council (CONICET) Buenos Aires Argentina National University of San Martin Buenos Aires Argentina University of Copenhagen Copenhagen Denmark Concordia University Montreal QC Canada University of Groningen Groningen Netherlands Missouri University of Science and Technology Rolla MO United States Mercator Research Institute on Global Commons and Climate Change (MCC) Berlin Germany Humboldt-University of Berlin Berlin Germany Cheikh Anta Diop University Dakar Senegal Stockholm University Stockholm Sweden University of Gothenburg Gothenburg Sweden Institute of Epidemiology Helmholtz Zentrum München—German Research Center for Environmental Health (GmbH) Neuherberg Germany European Space Agency (ESA) - European Centre for Space Applications and Telecommunications (ECSAT) Oxford United Kingdom Federal University of Santa Catarina Florianopolis Brazil Institute for Global Environmental Strategies (IGES) Hayama Japan University of Helsinki Helsinki Finland Yonsei University Graduate Seoul South Korea Chinese Academy of Macroeconomic

The years 2023 and 2024 were characterized by unprecedented warming across the globe, underscoring the urgency of climate action. Robust science advice for decision makers on subjects as complex as climate change requires deep cross- and interdisciplinary understanding. However, navigating the ever-expanding and diverse peer-reviewed literature on climate change is enormously challenging for individual researchers. We elicited expert input through an online questionnaire (188 respondents from 45 countries) and prioritized 10 key advances in climate-change research with high policy relevance. The insights span a wide range of areas, from changes in methane and aerosol emissions to the factors shaping citizens’ acceptance of climate policies. This synthesis and communications effort forms the basis for a science-policy report distributed to party delegations ahead of the 29th session of the Conference of the Parties (COP29) to inform their positions and arguments on critical issues, including heat-adaptation planning, comprehensive mitigation strategies, and strengthened governance in energy-transition minerals value chains. © 2025 The Authors

关键词： adaptation climate policy climate science governance just transition mitigation resilience science policy

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Modern applications of machine learning in quantum sciences

arXiv

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arXiv 2022年

作者： Dawid, Anna Arnold, Julian Requena, Borja Gresch, Alexander Plodzien, Marcin Donatella, Kaelan Nicoli, Kim A. Stornati, Paolo Koch, Rouven Büttner, Miriam Okula, Robert Muñoz–Gil, Gorka Vargas–Hernández, Rodrigo A. Cervera-Lierta, Alba Carrasquilla, Juan Dunjko, Vedran Gabrié, Marylou Huembeli, Patrick van Nieuwenburg, Evert Vicentini, Filippo Wang, Lei Wetzel, Sebastian J. Carleo, Giuseppe Greplová, Eliška Krems, Roman Marquardt, Florian Tomza, Michal Lewenstein, Maciej Dauphin, Alexandre Faculty of Physics University of Warsaw Poland ICFO - Institut de Ciències Fotòniques The Barcelona Institute of Science and Technology Castelldefels Barcelona08860 Spain Center for Computational Quantum Physics Flatiron Institute New York United States Department of Physics University of Basel Switzerland Institute for Theoretical Physics Heinrich Heine University Düsseldorf Germany Institute for Quantum Inspired and Quantum Optimization Hamburg University of Technology Germany Université de Paris CNRS Laboratoire Matériaux et Phénomènes Quantiques France Machine Learning Group Technische Universität Berlin Germany BIFOLD Berlin Institute for the Foundations of Learning and Data Berlin10587 Germany Department of Applied Physics Aalto University Espoo Finland Institute of Physics Albert-Ludwig University of Freiburg Germany International Centre for Theory of Quantum Technologies University of Gdańsk Poland Department of Algorithms and System Modeling Faculty of Electronics Faculty of Electronics Telecommunications and Informatics Gdańsk University of Technology Poland Institute for Theoretical Physics University of Innsbruck Austria Department of Chemistry University of Toronto Canada Vector Institute for Artificial Intelligence MaRS Centre Toronto Canada Department of Chemistry and Chemical Biology McMaster University Hamilton Canada Barcelona Supercomputing Center Spain LIACS Leiden University Netherlands CMAP École Polytechnique France Switzerland Menten AI Inc. Palo AltoCA United States Niels Bohr Institute Copenhagen Denmark CPHT CNRS École Polytechnique Institut Polytechnique de Paris PalaiseauF-91128 France Beijing National Lab for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing China Songshan Lake Materials Laboratory Dongguan China Perimeter Institute for Theoretical Physics Waterloo Canada Kavli Institute of Nanoscience Delft University of Technology DelftNL-2600 GA Netherlands Department of

In this book, we provide a comprehensive introduction to the most recentadvances in the application of machine learning methods in quantum sciences. Wecover the use of deep learning and kernel methods in supervised, unsupervised,and reinforcement learning algorithms for phase classification, representationof many-body quantum states, quantum feedback control, and quantum circuitsoptimization. Moreover, we introduce and discuss more specialized topics suchas differentiable programming, generative models, statistical approach tomachine learning, and quantum machine learning. © 2022, CC BY.

关键词： Deep learning

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Quantum Computing for High-Energy Physics State of the Art and Challenges Summary of the QC4HEP Working Group

arXiv

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arXiv 2023年

作者： Di Meglio, Alberto Jansen, Karl Tavernelli, Ivano Alexandrou, Constantia Arunachalam, Srinivasan Bauer, Christian W. Borras, Kerstin Carrazza, Stefano Crippa, Arianna Croft, Vincent de Putter, Roland Delgado, Andrea Dunjko, Vedran Egger, Daniel J. Fernández-Combarro, Elias Fuchs, Elina Funcke, Lena González-Cuadra, Daniel Grossi, Michele Halimeh, Jad C. Holmes, Zoë Kühn, Stefan Lacroix, Denis Lewis, Randy Lucchesi, Donatella Martinez, Miriam Lucio Meloni, Federico Mezzacapo, Antonio Montangero, Simone Nagano, Lento Radescu, Voica Ortega, Enrique Rico Roggero, Alessandro Schuhmacher, Julian Seixas, Joao Silvi, Pietro Spentzouris, Panagiotis Tacchino, Francesco Temme, Kristan Terashi, Koji Tura, Jordi Tüysüz, Cenk Vallecorsa, Sofia Wiese, Uwe-Jens Yoo, Shinjae Zhang, Jinglei GenevaCH-1211 Switzerland CQTA Deutsches Elektronen-Synchrotron DESY Platanenallee 6 Zeuthen15738 Germany Computation-based Science and Technology Research Center The Cyprus Institute 20 Constantinou Kavafi str. Nicosia2121 Cyprus IBM Quantum IBM Research – Zurich Rüschlikon8803 Switzerland Department of Physics University of Cyprus PO Box 20537 Nicosia1678 Cyprus IBM Quantum IBM Research 1101 Kitchawan Rd Yorktown HeightsNY United States Physics Division LBNL - M/S 50A5104 1 Cyclotron Rd BerkeleyCA United States Deutsches Elektronen-Synchrotron DESY Notkestrasse 85 Hamburg22607 Germany RWTH Aachen University Templergraben 55 Aachen52062 Germany TIF Lab Dipartimento di Fisica Università degli Studi di Milano INFN Sezione di Milano Milan Italy Institut für Physik Humboldt-Universität zu Berlin Newtonstr. 15 Berlin12489 Germany haQaLi Applied Quantum Algorithms Leiden Netherlands Physics Division Oak Ridge National Laboratory Oak RidgeTN37831 United States Department of Computer Science Facultad de Ciencias University of Oviedo Asturias33007 Spain Institute of Theoretical Phyiscs Leibniz University Hannover Hannover30167 Germany Physikalisch-Technische Bundesanstalt Braunschweig38116 Germany University of Bonn Nußallee 14-16 Bonn53115 Germany Institute for Theoretical Physics University of Innsbruck Innsbruck6020 Austria Institute for Quantum Optics and Quantum Information the Austrian Academy of Sciences Innsbruck6020 Austria Department of Physics Arnold Sommerfeld Center for Theoretical Physics Ludwig-Maximilians-Universität München Germany Munich Center for Quantum Science and Technology Germany LausanneCH-1015 Switzerland Paris-Saclay University CNRS IN2P3 IJCLab Orsay91405 France Department of Physics and Astronomy York University TorontoONM3J 1P3 Canada Department of Physics and Astronomy Università di Padova V. Marzolo 8 PadovaI-35131 Italy INFN - Sezione di Padova Via Marzolo 8 Padova35131 Italy Ni

Quantum computers offer an intriguing path for a paradigmatic change of computing in the natural sciences and beyond, with the potential for achieving a so-called quantum advantage, namely a significant (in some cases exponential) speed-up of numerical simulations. The rapid development of hardware devices with various realizations of qubits enables the execution of small scale but representative applications on quantum computers. In particular, the high-energy physics community plays a pivotal role in accessing the power of quantum computing, since the field is a driving source for challenging computational problems. This concerns, on the theoretical side, the exploration of models which are very hard or even impossible to address with classical techniques and, on the experimental side, the enormous data challenge of newly emerging experiments, such as the upgrade of the Large Hadron Collider. In this roadmap paper, led by CERN, DESY and IBM, we provide the status of high-energy physics quantum computations and give examples for theoretical and experimental target benchmark applications, which can be addressed in the near future. Having the IBM 100 100 challenge in mind, where possible, we also provide resource estimates for the examples given using error mitigated quantum computing. © 2023, CC BY-SA.

关键词： High energy physics

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Perspectives on adaptive dynamical systems

arXiv

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arXiv 2023年

作者： Sawicki, Jakub Berner, Rico Loos, Sarah A.M. Anvari, Mehrnaz Bader, Rolf Barfuss, Wolfram Botta, Nicola Brede, Nuria Franović, Igor Gauthier, Daniel J. Goldt, Sebastian Hajizadeh, Aida Hövel, Philipp Karin, Omer Lorenz-Spreen, Philipp Miehl, Christoph Mölter, Jan Olmi, Simona Schöll, Eckehard Seif, Alireza Tass, Peter A. Volpe, Giovanni Yanchuk, Serhiy Kurths, Jürgen Potsdam Institute for Climate Impact Research Telegrafenberg Potsdam14473 Germany Fachhochschule Nordwestschweiz FHNW Leonhardsstrasse 6 Basel4009 Switzerland Department of Physics Humboldt-Universität zu Berlin Newtonstraße 15 Berlin12489 Germany DAMTP University of Cambridge Wilberforce Road CambridgeCB3 0WA United Kingdom Fraunhofer Institute for Algorithms and Scientific Computing Schloss Birlinghoven Sankt-Augustin53757 Germany Institute of Systematic Musicology University of Hamburg Germany Transdisciplinary Research Area: Sustainable Futures University of Bonn Bonn53113 Germany University of Bonn Bonn53113 Germany Department of Computer Science and Engineering Chalmers University of Technology Göteborg412 96 Sweden Department of Computer Science University of Potsdam An der Bahn 2 Potsdam14476 Germany Scientific Computing Laboratory Center for the Study of Complex Systems Institute of Physics Belgrade University of Belgrade Pregrevica 118 Belgrade11080 Serbia The Ohio State University Department of Physics and Electrical and Computer Engineering 191 West Woodruff Ave ColumbusOH43210 United States ResCon Technologies LLC 1275 Kinnear Rd. Suite 239 ColumbusOH43212 United States Trieste Italy Research Group Comparative Neuroscience Leibniz Institute for Neurobiology Magdeburg Germany Theoretical Physics Saarland University Saarbrücken66123 Germany Center for Biophysics Saarland University Saarbrücken66123 Germany Department of Mathematics Imperial College London United Kingdom Center for Adaptive Rationality Max Planck Institute for Human Development Lentzeallee 94 Berlin14195 Germany Max Planck Institute for Brain Research Max-von-Laue-Straße 4 Frankfurt am Main60438 Germany Technical University of Munich School of Life Sciences Alte Akademie 8 Freising85354 Germany Department of Mathematics School of Computation Information and Technology Technical University of Munich Boltzmannstraße 3 Garching bei München8574

Adaptivity is a dynamical feature that is omnipresent in nature, socio-economics, and technology. For example, adaptive couplings appear in various real-world systems like the power grid, social, and neural networks, and they form the backbone of closed-loop control strategies and machine learning algorithms. In this article, we provide an interdisciplinary perspective on adaptive systems. We reflect on the notion and terminology of adaptivity in different disciplines and discuss which role adaptivity plays for various fields. We highlight common open challenges, and give perspectives on future research directions, looking to inspire interdisciplinary approaches. Copyright © 2023, The Authors. All rights reserved.

关键词： Dynamical systems

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TRACKING CONTROL IN THE PRESENCE OF NONLINEAR DYNAMIC FRICTIONAL EFFECTS: ROBOT EXTENSION

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Asian Journal of Control 2008年第3期1卷

作者： M. Feemster D.M. Dawson A. Behal W. Dixon Matthew Feemster received the B.S degree in Electrical Engineering from Clemson University Clemson South Carolina in December 1994. Upon graduation he remained at Clemson University and received the M.S. degree in Electrical Engineering in 1997. During this time he also served as a research/teaching assistant. His research work focused on the design and implementation of various nonlinear control algorithms with emphasis on the induction motor and mechanical systems with friction present. He is currently working toward his Ph.D. degree in Electrical Engineering at Clemson University. Darren M. Dawson was born in 1962 in Macon Georgia. He received an Associate Degree in Mathematics from Macon Junior College in 1982 and a B.S. Degree in Electrical Engineering from the Georgia Institute of Technology in 1984. He then worked for Westinghouse as a control engineer from 1985 to 1987. In 1987 he returned to the Georgia Institute of Technology where he received the Ph.D. Degree in Electrical Engineering in March 1990. During this time he also served as a research/teaching assistant. In July 1990 he joined the Electrical and Computer Engineering Department and the Center for Advanced Manufacturing (CAM) at Clemson University where he currently holds the position of Professor. Under the CAM director's supervision he currently leads the Robotics and Manufacturing Automation Laboratory which is jointly operated by the Electrical and Mechanical Engineering departments. His main research interests are in the fields of nonlinear based robust adaptive and learning control with application to electro-mechanical systems including robot manipulators motor drives magnetic bearings flexible cables flexible beams and high-speed transport systems. Aman Behal was born in India in 1973. He received his Masters Degree in Electrical Engineering from Indian Institute of Technology Bombay in 1996. He is currently working towards a Ph.D in Controls and Robotics at Clemson University. His research focuses on the control of no

In this paper, we extend the observer/control strategies previously published in [25] to an n -link, serially connected, direct drive, rigid link, revolute robot operating in the presence of nonlinear friction effects modeled by the Lu-Gre model. In addition, we also present a new adaptive control technique for compensating for the nonlinear parameterizable Stribeck effects. Specifically, an adaptive observer/controller scheme is developed which contains a feedforward approximation of the Stribeck effects. This feedforward approximation is used in a composite controller/observer strategy which forces the average square integral of the position tracking error to an arbitrarily small value. Experimental results are included to illustrate the performance of the proposed controllers.

关键词： Friction compensation nonlinear control

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Proteomic Progress: Bangalore Institute Becomes a Major Center of Biotech Research

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CHEMISTRY & BIOLOGY 2010年第3期17卷 207-208页

作者： Shekhar, Chandra Main Text In the U.S. or Europe India is often associated with information technology or service outsourcing not with scientific research. Nonetheless largely unnoticed by western media India has been making strides toward becoming a research powerhouse in the life sciences. Enjoying unique manpower and cost advantages this country now has several major universities and scientific institutions with active programs in this area. Spurred by supportive government agencies these institutions are producing an increasing number of publications patents and industry spin-offs. Consider Bangalore-based Institute of Bioinformatics (IOB) a relatively small 40 member outfit that has nonetheless become a major global player in proteomics research. In less than a decade of existence the institute has produced what is arguably the world's best curated protein database and is well on its way to replicating this success in cancer biomarkers proteogenomics and signaling pathways. “We undertake projects that most other labs would find extremely hard” says IOB's founder and director Akhilesh Pandey M.D. Ph.D. who is also a researcher at Johns Hopkins University School of Medicine. “And we accomplish them in a time frame that would be virtually unthinkable elsewhere.” Proteogenomics the use of proteomics to annotate genes is an area where IOB has carved out a niche for itself. This is not a vain boast. Take for instance the Institute's Human Protein Reference Database an unprecedented online compendium of curated protein information. Containing information about more than 27000 proteins and 39000 protein-protein interactions the database is the fruit of several years of effort from curators who sifted through more than 2000000 research papers. Unlike most other protein databases IOB's creation encapsulates virtually every relevant feature of each protein—function sequence domains motifs interactions expression localization modifications disease associations—and includes results obtained w

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