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检索条件"机构=Laboratory of Function-Structure and Protein Engineering"
16 条 记 录,以下是1-10 订阅
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Efficient degradation of azo dyes by an engineered myoglobin with a modified heme active site showing high peroxidase activity
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Process Biochemistry 2025年 156卷 153-163页
作者: Jing-Jing Liu Bin-Bin Jiang Ya-Han Zhu Shu-Qin Gao Ying-Wu Lin School of Chemistry and Chemical Engineering University of South China Hengyang 421001 China Laboratory of Protein Structure and Function University of South China Hengyang 421001 China
Azo dyes, widely used in global textiles, persist in wastewater causing significant ecological and health risks, necessitating efficient degradation to protect ecosystems and public health. The development of artifici...
来源: 评论
Crystal enigma: Understanding diverse protein conformational dynamics, ligand selectivity and interaction in multi-space group crystals using computational modelling
Results in Chemistry
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Results in Chemistry 2025年 16卷
作者: Mfeka, Mbalenhle Onisuru, Olalekan Pandian, Ramesh Sayed, Yasien Khoza, Thandeka Achilonu, Ikechukwu Department of Biochemistry School of Life Sciences College of Agriculture Engineering & Science University of KwaZulu-Natal Pietermaritzburg 3209 South Africa Protein Structure-Function and Research Laboratory School of Molecular and Cell Biology Faculty of Science University of the Witwatersrand Braamfontein Johannesburg 2000 South Africa
Empirical structural methods have been instrumental in drug design, but they often fall short of capturing protein dynamics. To address this limitation, computer-aided drug design (CADD) is essential. Given that Schis... 详细信息
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Steric Effect Modulating the structures of Trinuclear Zinc Carboxylate Frameworks
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Chinese Journal of Structural Chemistry 2016年 第9期35卷 1413-1419页
作者: 孙允凯 谢睿 王小峰 文格波 林英武 School of Chemistry and Chemical Engineering University of South China Laboratory of Protein Structure and Function University of South China
By the reaction of different aromatic dicarboxylic acid with zinc nitrate, three metal-carboxylate frameworks, [Zn3(BDC)3(EtOH)2](1), [Zn3(BDC)3(py)2]·2DMF(2), and [Zn3(NH2-BDC)3(H2O)2]·5DMF... 详细信息
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Uranyl-cytochrome b_5 interaction regulated by surface mutations and cytochrome c
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Nuclear Science and Techniques 2015年 第5期26卷 44-47页
作者: 孙美慧 杜可杰 聂长明 文格波 林英武 School of Chemistry and Chemical Engineering University of South China Laboratory of Protein Structure and Function University of South China
Understanding uranium-protein interaction is important for revealing the mechanism of uranyl ion(UO2+2)toxicity. In this study, we investigated the interaction between UO2+2and a quadruple mutant of cytochrome b5(E44/... 详细信息
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Rational design of functional metalloenzymes in myoglobin for green biocatalysis
Rational design of functional metalloenzymes in myoglobin fo...
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作者: Ying-Wu Lin School of Chemistry and Chemical Engineering University of South China Laboratory of Protein Structure and Function University of South China
Design of functional metalloenzymes have addressed much attention in the last decade. Myoglobin(Mb) is an ideal model protein for heme protein design, and we have rationally designed some functional enzymes in Mb by u... 详细信息
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Rational design of functional metalloenzymes in myoglobin for green biocatalysis
Rational design of functional metalloenzymes in myoglobin fo...
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中国化学会第六届全国生物物理化学会议(NCBPC-6)
作者: 林英武 School of Chemistry and Chemical Engineering University of South China Laboratory of Protein Structure and Function University of South China
Design of functional metalloenzymes have addressed much attention in the last decade. Myoglobin(Mb) is an ideal model protein for heme protein design, and we have rationally designed some functional enzymes in Mb by... 详细信息
来源: 评论
Rational Design of an Artificial Hydrolytic Nuclease by Introduction of A Sodium Copper Chlorophyllin in L29e Myoglobin
SSRN
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SSRN 2022年
作者: Dong, Yao Chen, Yu-Mei Kong, Xiang-Jun Gao, Shu-Qin Lang, Jia-Jia Lin, Ying-Wu Du, Ke-Jie School of Chemistry and Chemical Engineering Laboratory of Protein Structure and Function Hunan Key Laboratory for the Design and Application of Actinide Complexes University of South China Hengyang421001 China
Heme proteins have recently emerged as promising artificial metalloenzymes for catalyzing diverse reactions. In this report, L29E Mb, a single mutant of myoglobin, was reconstituted with a sodium copper cholorophyllin... 详细信息
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Oncoprotein LAMTOR5-mediated CHOP silence via DNA hypermethylation and miR-182/miR-769 in promotion of liver cancer growth
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中国药理学报(英文版) 2024年 第12期45卷 2625-2645页
作者: Xue Wang Qian-qian Li Yan-xin Tang Ye Li Lu Zhang Fei-fei Xu Xue-li Fu Kai Ye Jia-qi Ma Shi-man Guo Fang-yuan Ma Zhi-yu Liu Xu-he Shi Xian-meng Li Hui-min Sun Yue Wu Wei-ying Zhang Li-hong Ye State Key Laboratory of Medicinal Chemical Biology Tianjin Key Laboratory of Protein SciencesDepartment of Biochemistry and Molecular BiologyCollege of Life SciencesNankai UniversityTianjin 300071China State Key Laboratory of Medicinal Chemical Biology Tianjin Key Laboratory of Protein SciencesDepartment of Biochemistry and Molecular BiologyCollege of Life SciencesNankai UniversityTianjin 300071China Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Biomedical Engineering Tianjin 300192China State Key Laboratory of Medicinal Chemical Biology Tianjin Key Laboratory of Protein SciencesDepartment of Biochemistry and Molecular BiologyCollege of Life SciencesNankai UniversityTianjin 300071China Institute of Radiation Medicine Peking Union Medical College & Chinese Academy of Medical SciencesTianjin 300192China State Key Laboratory of Medicinal Chemical Biology Tianjin Key Laboratory of Protein SciencesDepartment of Biochemistry and Molecular BiologyCollege of Life SciencesNankai UniversityTianjin 300071China Center for Cell Structure and Function Shandong Provincial Key Laboratory of Animal Resistance BiologyCollaborative Innovation Center of Cell Biology in Universities of ShandongCollege of Life SciencesShandong Normal UniversityJinan 250014China
C/EBP homologous protein(CHOP)triggers the death of multiple cancers via endoplasmic reticulum(ER)***,the function and regulatory mechanism of CHOP in liver cancer remain *** have reported that late endosomal/lysosoma... 详细信息
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Novel Copper Complexes with Tridentate Ligand: Synthesis, Crystal structure, DNA Binding and Anticancer Studies
SSRN
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SSRN 2023年
作者: Chen, Yu-Mei Liu, Yu-Can Wang, Jin-Quan Ou, Guang-Chuan Wang, Xiao-Feng Gao, Shu-Qin Lin, Ying-Wu Du, Ke-Jie School of Chemistry and Chemical Engineering Laboratory of Protein Structure and Function Hunan Key Laboratory for the Design and Application of Actinide Complexes University of South China Hengyang421001 China School of Biosciences & Biopharmaceutics Guangdong Pharmaceutical University Guangzhou510000 China Department of Biology and Chemistry Hunan University of Science and Engineering Yongzhou425199 China
Metal complexes, particularly copper (II) complexes, are often used as anticancer drugs due to their ability to generate reactive oxygen species (ROS) in cells. Four copper (II) complexes were designed based on ligand... 详细信息
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Variation in Polyamine Content among 12 Pollinated Wheat Genotypes under Drought Stress Condition
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Open Journal of Geology 2017年 第8期7卷 1094-1109页
作者: Mahdi Seyedsalehi Parisa Sharifi Ombretta Paladino Gassan Hodaifa Elba C. Villegas Randa M. Osman Department of Environmental Engineering Science and Research Branch Islamic Azad University Tehran Iran Department of Agronomy Faculty of Agriculture Urmia University Urmia Iran Department of Civil Chemical and Environmental Engineering Università di Genova Genoa Italy Department of Molecular Biology and Biochemical Engineering Chemical Engineering Area University of Pablo de Olavide Seville Spain Laboratory of Function-Structure and Protein Engineering Center for Research on Biotechnology Autonomous University of Morelos State (UAEM) Cuernavaca Mexico Department of Chemical Engineering and Pilot Plant National Research Centre Cairo Egypt
The present work aims to study the drought stress effects on polyamine content and its relationship with growth and development in seeds, during cell division (from the beginning and until 17 days after pollination) a... 详细信息
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