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Artificial Intelligence for Imaging Diagnostics in Neurosurgery

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Artificial Intelligence for Imaging Diagnostics in Neurosurg...

2019 International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2019

作者： Letyagin, Andrey Yu. Degtyareva, Liana O. Golushko, Sergey K. Rzaev, Jamil A. Amelin, Mihail E. Pavlovsky, Evgeniy N. Tuchinov, Bair N. Amelina, Evgeniya V. Moisak, Galina I. Bulgakova, Ekaterina G. Novosibirsk State University Novosibirsk Russia Federal State Budget Institution Federal Center of Neurosurgery Novosibirsk Russia FSBI 'Federal Neurosurgical Center' Novosibirsk Russia Stread Data Analytics Machine Learning Lab. Novosibirsk State University Novosibirsk Russia

ISBN: (纸本)9781728144016

Improving the accuracy and timeliness of medical imaging in everyday clinical neurosurgery practice is an urgent problem for the health care of all countries. This problem will be solved with the help of artificial intelligence (AI). By performing the search and contouring of 'suspicious' pathological objects, making automatic measurements on 3D medical images (MRI, CT), formalizing quantitative indicators and compiling medical statistical reports, AI can solve diagnostic problems in radiology and medical imaging. The effect of introducing AI will be at least a more accurate and quick interpretation of images, implemented through a set of decision-making tools for medical specialists. © 2019 IEEE.

关键词： Neurosurgery

Rigid and non-rigid motion compensation in weight-bearing cone-beam CT of the knee using (noisy) inertial measurements

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arXiv 2021年

作者： Maier, Jennifer Nitschke, Marlies Choi, Jang-Hwan Gold, Garry Fahrig, Rebecca Eskofier, Bjoern M. Maier, Andreas Pattern Recognition Lab Friedrich-Alexander-Universität Erlangen-Nürnberg Erlangen Germany Machine Learning and Data Analytics Lab Friedrich-Alexander-Universität Erlangen-Nürnberg Erlangen Germany Division of Mechanical and Biomedical Engineering Ewha Womans University Seoul Korea Republic of Department of Radiology School of Medicine Stanford University StanfordCA United States Innovation Advanced Therapies Siemens Healthcare GmbH Forchheim Germany

Involuntary subject motion is the main source of artifacts in weight-bearing cone-beam CT of the knee. To achieve image quality for clinical diagnosis, the motion needs to be compensated. We propose to use inertial measurement units (IMUs) attached to the leg for motion estimation. We perform a simulation study using real motion recorded with an optical tracking system. Three IMU-based correction approaches are evaluated, namely rigid motion correction, non-rigid 2D projection deformation and non-rigid 3D dynamic reconstruction. We present an initialization process based on the system geometry. With an IMU noise simulation, we investigate the applicability of the proposed methods in real applications. All proposed IMU-based approaches correct motion at least as good as a state-of-the-art marker-based approach. The structural similarity index and the root mean squared error between motion-free and motion corrected volumes are improved by 24-35% and 78-85%, respectively, compared with the uncorrected case. The noise analysis shows that the noise levels of commercially available IMUs need to be improved by a factor of 105 which is currently only achieved by specialized hardware not robust enough for the application. The presented study confirms the feasibility of this novel approach and defines improvements necessary for a real application. Copyright © 2021, The Authors. All rights reserved.

关键词： Motion compensation

Reducing over-smoothness in speech synthesis using Generative Adversarial Networks

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Reducing over-smoothness in speech synthesis using Generativ...

IEEE Region 8 International Conference on Computational Technologies in Electrical and Electronics Engineering, SIBIRCON

作者： Leyuan Sheng Evgeniy N. Pavlovskiy Novosibirsk State University Novosibirsk Russia Stream Data Analytics and Machine Learning laboratory Novosibirsk State University Novosibirsk Russia

Speech synthesis is widely used in many practical applications. In recent years, speech synthesis technology has developed rapidly. However, one of the reasons why synthetic speech is unnatural is that it often has over-smoothness. In order to improve the naturalness of synthetic speech, we first extract the mel-spectrogram of speech and convert it into a real image, then take the over-smooth mel-spectrogram image as input, and use image-to-image translation Generative Adversarial Networks(GANs) framework to generate a more realistic mel-spectrogram. Finally, the results show that this method greatly reduces the over-smoothness of synthesized speech and is more close to the mel-spectrogram of real speech.

关键词： Generative adversarial networks Speech synthesis Spectrogram Generators Hidden Markov models Training

Uncertainty Quantification in machine learning for Engineering Design and Health Prognostics: A Tutorial

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arXiv 2023年

作者： Nemani, Venkat Biggio, Luca Huan, Xun Hu, Zhen Fink, Olga Tran, Anh Wang, Yan Zhang, Xiaoge Hu, Chao Department of Mechanical Engineering Iowa State University AmesIA50011 United States Data Analytics Lab ETH Zürich Switzerland Department of Mechanical Engineering University of Michigan Ann ArborMI48109 United States Department of Industrial and Manufacturing Systems Engineering University of Michigan-Dearborn DearbornMI48128 United States Intelligent Maintenance and Operations Systems EPFL Lausanne12309 Switzerland Scientific Machine Learning Sandia National Laboratories AlbuquerqueNM87123 United States George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology AtlantaGA30332 United States Department of Industrial and Systems Engineering The Hong Kong Polytechnic University Kowloon Hong Kong New Territories Hong Kong Department of Mechanical Engineering University of Connecticut StorrsCT06269 United States

On top of machine learning (ML) models, uncertainty quantification (UQ) functions as an essential layer of safety assurance that could lead to more principled decision making by enabling sound risk assessment and management. The safety and reliability improvement of ML models empowered by UQ has the potential to significantly facilitate the broad adoption of ML solutions in high-stakes decision settings, such as healthcare, manufacturing, and aviation, to name a few. In this tutorial, we aim to provide a holistic lens on emerging UQ methods for ML models with a particular focus on neural networks and the applications of these UQ methods in tackling engineering design as well as prognostics and health management problems. Toward this goal, we start with a comprehensive classification of uncertainty types, sources, and causes pertaining to UQ of ML models. Next, we provide a tutorial-style description of several state-of-the-art UQ methods: Gaussian process regression, Bayesian neural network, neural network ensemble, and deterministic UQ methods focusing on spectral-normalized neural Gaussian process. Established upon the mathematical formulations, we subsequently examine the soundness of these UQ methods quantitatively and qualitatively (by a toy regression example) to examine their strengths and shortcomings from different dimensions. Then, we review quantitative metrics commonly used to assess the quality of predictive uncertainty in classification and regression problems. Afterward, we discuss the increasingly important role of UQ of ML models in solving challenging problems in engineering design and health prognostics. Two case studies with source codes available on GitHub are used to demonstrate these UQ methods and compare their performance in the life prediction of lithium-ion batteries at the early stage (case study 1) and the remaining useful life prediction of turbofan engines (case study 2). © 2023, CC BY.

关键词： machine learning

Multidimensional scaling, Sammon mapping, and Isomap: Tutorial and survey

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arXiv 2020年

作者： Ghojogh, Benyamin Ghodsi, Ali Karray, Fakhri Crowley, Mark Department of Electrical and Computer Engineering Machine Learning Laboratory University of Waterloo WaterlooON Canada Department of Statistics and Actuarial Science David R. Cheriton School of Computer Science Data Analytics Laboratory University of Waterloo WaterlooON Canada Department of Electrical and Computer Engineering Centre for Pattern Analysis and Machine Intelligence University of Waterloo WaterlooON Canada

Multidimensional Scaling (MDS) is one of the first fundamental manifold learning methods. It can be categorized into several methods, i.e., classical MDS, kernel classical MDS, metric MDS, and non-metric MDS. Sammon mapping and Isomap can be considered as special cases of metric MDS and kernel classical MDS, respectively. In this tutorial and survey paper, we review the theory of MDS, Sammon mapping, and Isomap in detail. We explain all the mentioned categories of MDS. Then, Sammon mapping, Isomap, and kernel Isomap are explained. Out-of-sample embedding for MDS and Isomap using eigenfunctions and kernel mapping are introduced. Then, Nystrom approximation and its use in landmark MDS and landmark Isomap are introduced for big data embedding. We also provide some simulations for illustrating the embedding by these methods. Copyright © 2020, The Authors. All rights reserved.

关键词： Embeddings

Stochastic Neighbor Embedding with Gaussian and Student-t Distributions: Tutorial and Survey

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arXiv 2020年

Stochastic Neighbor Embedding (SNE) is a manifold learning and dimensionality reduction method with a probabilistic approach. In SNE, every point is consider to be the neighbor of all other points with some probability and this probability is tried to be preserved in the embedding space. SNE considers Gaussian distribution for the probability in both the input and embedding spaces. However, t-SNE uses the Student-t and Gaussian distributions in these spaces, respectively. In this tutorial and survey paper, we explain SNE, symmetric SNE, t-SNE (or Cauchy-SNE), and t-SNE with general degrees of freedom. We also cover the out-of-sample extension and acceleration for these methods. Copyright © 2020, The Authors. All rights reserved.

关键词： Gaussian distribution

Locally linear embedding and its variants: Tutorial and survey

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arXiv 2020年

作者： Ghojogh, Benyamin Ghodsi, Ali Karray, Fakhri Crowley, Mark Department of Electrical and Computer Engineering Machine Learning Laboratory University of Waterloo WaterlooON Canada Department of Statistics and Actuarial Science & David R. Cheriton School of Computer Science Data Analytics Laboratory University of Waterloo WaterlooON Canada Department of Electrical and Computer Engineering Centre for Pattern Analysis and Machine Intelligence University of Waterloo WaterlooON Canada

This is a tutorial and survey paper for Locally Linear Embedding (LLE) and its variants. The idea of LLE is fitting the local structure of manifold in the embedding space. In this paper, we first cover LLE, kernel LLE, inverse LLE, and feature fusion with LLE. Then, we cover out-of-sample embedding using linear reconstruction, eigenfunctions, and kernel mapping. Incremental LLE is explained for embedding streaming data. Landmark LLE methods using the Nystrom approximation and locally linear landmarks are explained for big data embedding. We introduce the methods for parameter selection of number of neighbors using residual variance, Procrustes statistics, preservation neighborhood error, and local neighborhood selection. Afterwards, Supervised LLE (SLLE), enhanced SLLE, SLLE projection, probabilistic SLLE, supervised guided LLE (using Hilbert-Schmidt independence criterion), and semi-supervised LLE are explained for supervised and semi-supervised embedding. Robust LLE methods using least squares problem and penalty functions are also introduced for embedding in the presence of outliers and noise. Then, we introduce fusion of LLE with other manifold learning methods including Isomap (i.e., ISOLLE), principal component analysis, Fisher discriminant analysis, discriminant LLE, and Isotop. Finally, we explain weighted LLE in which the distances, reconstruction weights, or the embeddings are adjusted for better embedding;we cover weighted LLE for deformed distributed data, weighted LLE using probability of occurrence, SLLE by adjusting weights, modified LLE, and iterative LLE. Copyright © 2020, The Authors. All rights reserved.

关键词： Iterative methods

Harnessing multimodal approaches for depression detection using large language models and facial expressions

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Npj mental health research

Npj mental health research 2024年第1期3卷 66页

作者： Misha Sadeghi Robert Richer Bernhard Egger Lena Schindler-Gmelch Lydia Helene Rupp Farnaz Rahimi Matthias Berking Bjoern M Eskofier Machine Learning and Data Analytics Lab (MaD Lab) Department Artificial Intelligence in Biomedical Engineering (AIBE) Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) Erlangen 91052 Germany. misha.sadeghi@fau.de. Machine Learning and Data Analytics Lab (MaD Lab) Department Artificial Intelligence in Biomedical Engineering (AIBE) Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) Erlangen 91052 Germany. Chair of Visual Computing (LGDV) Department of Computer Science Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) Erlangen 91058 Germany. Chair of Clinical Psychology and Psychotherapy (KliPs) Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) Erlangen 91052 Germany. Translational Digital Health Group Institute of AI for Health Helmholtz Zentrum München - German Research Center for Environmental Health Neuherberg 85764 Germany.

Detecting depression is a critical component of mental health diagnosis, and accurate assessment is essential for effective treatment. This study introduces a novel, fully automated approach to predicting depression severity using the E-DAIC dataset. We employ Large Language Models (LLMs) to extract depression-related indicators from interview transcripts, utilizing the Patient Health Questionnaire-8 (PHQ-8) score to train the prediction model. Additionally, facial data extracted from video frames is integrated with textual data to create a multimodal model for depression severity prediction. We evaluate three approaches: text-based features, facial features, and a combination of both. Our findings show the best results are achieved by enhancing text data with speech quality assessment, with a mean absolute error of 2.85 and root mean square error of 4.02. This study underscores the potential of automated depression detection, showing text-only models as robust and effective while paving the way for multimodal analysis.

关键词：

learning with Group Noise

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arXiv 2021年

作者： Wang, Qizhou Yao, Jiangchao Gong, Chen Liu, Tongliang Gong, Mingming Yang, Hongxia Han, Bo Department of Computer Science Hong Kong Baptist University Hong Kong Key Laboratory of Intelligent Perception and Systems for High-Dimensional Information of MoE School of Computer Science and Engineering Nanjing University of Science and Technology China Data Analytics and Intelligence Lab Alibaba Group China Department of Computing Hong Kong Polytechnic University Hong Kong Trustworthy Machine Learning Lab School of Computer Science University of Sydney Australia School of Mathematics and Statistics University of Melbourne Australia

machine learning in the context of noise is a challenging but practical setting to plenty of real-world applications. Most of the previous approaches in this area focus on the pairwise relation (casual or correlational relationship) with noise, such as learning with noisy labels. However, the group noise, which is parasitic on the coarse-grained accurate relation with the fine-grained uncertainty, is also universal and has not been well investigated. The challenge under this setting is how to discover true pairwise connections concealed by the group relation with its fine-grained noise. To overcome this issue, we propose a novel Max-Matching method for learning with group noise. Specifically, it utilizes a matching mechanism to evaluate the relation confidence of each object (cf. Figure 1) w.r.t. the target, meanwhile considering the Non-IID characteristics among objects in the group. Only the most confident object is considered to learn the model, so that the fine-grained noise is mostly dropped. The performance on a range of real-world datasets in the area of several learning paradigms demonstrates the effectiveness of Max-Matching. Copyright © 2021, The Authors. All rights reserved.

关键词： machine learning