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2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology

作者： Zhu, Xiaoyue Mills, Kristen L. Peters, Portia R. Naruse, Keiji Csete, Marie E. Thouless, M.D. Takayama, Shuichi Department of Biomedical Engineering University of Michigan Ann Arbor MI 48109 United States Department of Mechanical Engineering University of Michigan Ann Arbor MI 48109 United States Department of Physiology Nagoya University Graduate School of Medicine Nagoya 466-8550 Japan Department of Anesthesiology Emory University School of Medicine Atlanta GA 30322 United States Department of Materials Science and Engineering University of Michigan Ann Arbor MI 48109 United States Macromolecular Science and Engineering Program University of Michigan Ann Arbor MI 48109 United States

ISBN: (纸本)0780387112

Here we present long-term patterning and response studies of neuro blasts on arrays of extracellular matrix (ECM) protein lines fabricated by cracking a polymer-supported thin film and selectively depositing proteins inside the cracks. Neuroblasts cultured for five days on the protein matrix switched between spreading and retraction upon changing the protein line width. This technique provides a novel tool to pursue further understanding of the basic mechanisms of neuroblast pathfinding on adhesion and morphology. Biomedical device design will also benefit from materials engineered with the reconfigurable protein patterns. © 2005 IEEE.

关键词： Proteins

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Matrix assisted pulsed laser evaporation of dexamethasone thin films

Matrix assisted pulsed laser evaporation of dexamethasone th...

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Nanoscale materials science in Biology and Medicine

作者： Patz, Timothy M. Doraiswamy, Anand Narayan, Roger J. Menegazzo, Nicola Kranz, Christine Mizakoff, Boris Zhong, Yinghui Bellamkonda, Ravi Modi, Rohit Chrisey, Douglas B. Bioengineering Program School of Material Science and Engineering Georgia Institute of Technology Atlanta GA United States Georgia Institute of Technology School of Chemistry and Biochemistry Atlanta GA 30332-0400 United States Coulter Department of Biomedical Engineering Georgia Institute of Technology NW Atlanta GA United States US Naval Research Laboratory Washington DC United States

We have demonstrated deposition of dexamethasone thin films via matrix assisted pulsed laser evaporation (MAPLE). Infrared analysis revealed that dexamethasone thin films deposited by MAPLE and by drop casting had a similar absorbance spectra. AFM imaging of the MAPLE-deposited dexamethasone thin film revealed 2-10 μm punctuate ring-like structures. Deposited dexamethasone was tested for positive bioactivity by treating primary microglia cells with lipopolysacchride and measuring nitric oxide (NO) production. The successful deposition of dexamethasone thin films can be used on neural implants to prevent tissue injury and inflammatory response. © 2005 materials Research Society.

关键词： Thin films

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Elastic Self-Healing during Shear Accommodation in Crystalline Nanotube Ropes

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Physical Review Letters 2005年第6期94卷 065502-065502页

作者： Haiyi Liang Moneesh Upmanyu Department of Modern Mechanics University of Science and Technology of China Hefei People's Republic of China Group for Simulation and Theory of Atomic-Scale Material Phenomena (stAMP) Materials Science Program Division of Engineering Colorado School of Mines Golden Colorado 80401 USA

Rigid-tube computations of simple (transverse) shear in crystalline nanotube ropes (CNTRs) reveal that shear modulus and strength increase and decrease with the tube radius, respectively. High modulus to strength ratios suggest that dislocations play a minor role during their plasticity. The computed shear moduli are in agreement with previous studies, although shape change and rolling-based shear may modify low strain and temperature behavior. The instability past the shear strength is due to shear localization via interlayer sliding, wherein stress relief results in significant elastic energy dissipation. Large-tube radius CNTRs accommodate large strains at minimal energetic cost during sliding, due to the increasingly cohesive and short range nature of the intertube potential. Fascinatingly, the crystal aids its recovery, implying that CNTRs may be promising materials for energy absorption and tribology.

关键词： .shape change PRL energetic cost shear strength shear modulus shear localization transverse shear tube radius intertube Elastic Self-Healing Shear Accommodation Crystalline Nanotube Ropes Rigid-tube CNTRs Large-tube

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Matrix Assisted Pulsed Laser Evaporation of Dexamethasone Thin Films

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MRS Online Proceedings Library 2005年第1期845卷 82-86页

作者： Patz, Timothy M. Doraiswamy, Anand Narayan, Roger J. Menegazzo, Nicola Kranz, Christine Mizakoff, Boris Zhong, Yinghui Bellamkonda, Ravi Modi, Rohit Chrisey, Douglas B. Bioengineering Program and School of Material Science and Engineering Georgia Institute of Technology Atlanta USA Georgia Institute of Technology School of Chemistry and Biochemistry Atlanta USA Coulter Department of Biomedical Engineering Georgia Institute of Technology Atlanta USA US Naval Research Laboratory Washington DC USA

We have demonstrated deposition of dexamethasone thin films via matrix assisted pulsed laser evaporation (MAPLE). Infrared analysis revealed that dexamethasone thin films deposited by MAPLE and by drop casting had a similar absorbance spectra. AFM imaging of the MAPLE-deposited dexamethasone thin film revealed 2–10 µm punctuate ring-like structures. Deposited dexamethasone was tested for positive bioactivity by treating primary microglia cells with lipopolysacchride and measuring nitric oxide (NO) production. The successful deposition of dexamethasone thin films can be used on neural implants to prevent tissue injury and inflammatory response.

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Thermal modeling of very small scale devices

Thermal modeling of very small scale devices

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2004 ASME International Mechanical engineering Congress and Exposition, IMECE 2004

作者： Bulusu, A. Walker, D.G. Interdisciplinary Program in Material Science Vanderbilt University Nashville TN 37235 Department of Mechanical Engineering Vanderbilt University Nashville TN 37235

As electronic device dimensions shrink down to the nanoscale regime, quantum effects such as electron tunneling and quantum confinement become significant. Along with quantum effects, various scattering processes such as carrier-carrier and carrier-defect scattering will influence device performance. Many transport models are not mature enough to couple the thermal effects with electronic solutions at such small scales. Incorporation of strong scattering influences on the electron transport in most cases is extremely difficult and computationally intensive. In this paper, we study a simple model that allows for integration of electron-phonon scattering effects in a nanotransistor. An acoustic deformation potential based electron-phonon scattering model is used to incorporate scattering in the device. A 7.5% drop in channel current was observed for a scattering rate of 1013/sec while current flow dropped by 50% for higher scattering rates. The effective channel resistance due to scattering was found to increase by a factor of 1.3. The results are compared to the I-V characteristics obtained using the non-equilibrium Green's function (NEGF) formalism and were found to match well. The effect of phase-breaking scattering was also studied using NEGF where a 25% decrease in channel current was obtained thus demonstrating the importance of including scattering effects with quantum transport. Copyright © 2004 by ASME.

关键词： Electronic equipment

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Carbon nanotube growth from Cu–Co alloys for field emission applications

Journal of Vacuum Science & Technology B: Microelectronics a...

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Journal of Vacuum science & Technology B: Microelectronics and Nanometer Structures Processing, Measurement, and Phenomena 2004年第3期22卷 1286-1289页

作者： W. Hofmeister W. P. Kang Y. M. Wong J. L. Davidson Interdisciplinary Graduate Program in Material Science Vanderbilt University Nashville Tennessee 37235 Interdisciplinary Graduate Program in Material Science and Department of Electrical Engineering and Computer Science Vanderbilt University Nashville Tennessee 37235 Department of Electrical Engineering and Computer Science Vanderbilt University Nashville Tennessee 37235

We have developed a method of catalyst preparation for carbon nanotube (CNT) growth that uses solid-state diffusion to precipitate Co particles in a Cu matrix and control the size and size distribution of catalyst particles. Copper is an excellent electrical and thermal conductor, and has a small or negligible solubility for Co. Cu–Co alloys of approximately 5 atm% Co were formed in bulk by splat quenching the liquid alloy and on Si substrates by e-beam evaporation of the alloy, sputtering of the alloy, and sputter deposition of thin films of pure Cu and Co. The Co easily precipitates from dilute solutions of Cu–Co with heat treatment. These alloys and films were used to generate uniform distributions of Co precipitates, and CNTs were successfully grown by plasma enhanced chemical vapor deposition (PE-CVD) and thermal CVD on the materials. These alloys can be patterned by photolithography and sputtering in order to grow CNTs in defined locations. Therefore, the technique is amenable to very large scale silicon integration for field emission applications. The results of this work and data from field emission studies are presented herein.

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Loose Abrasive Lapping of Optical Glass with Different Lapping Plates and Its Interpretation

Loose Abrasive Lapping of Optical Glass with Different Lappi...

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Optical Fabrication and Testing, OFT 2004

作者： Shafrir, Shai N. Lambropoulos, John C. Jacobs, Stephen D. Material Science Program Department of Mechanical Engineering University of Rochester 240 East River Road RochesterNY14623 United States University of Rochester 240 East River Road RochesterNY14623 United States

Loose Abrasive Lapping was studied and analyzed for different lapping plates. An examination of lapping plate hardness and Preston's Coefficient showed an optimization in process efficiency with an intermediate la... 详细信息

ISBN: (纸本)1557527792

关键词： Hardness

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The effects of process parameters on size, density, structure, and field emission properties of Pd-catalyzed carbon nanotubes synthesized by thermal chemical vapor deposition

The effects of process parameters on size, density, structur...

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International Conference on Vacuum Nanoelectronics (IVNC)

作者： S. Wei W.P. Kang W.H. Hofmeister J.L. Davidson Y.M. Wong J.H. Huang Interdisciplinary Graduate Program in Material Science Vanderbilt University Nashville TN USA Department of Electrical Engineering and Computer Science Vanderbilt University Nashville TN USA Department of Chemical Engineering Vanderbilt University Nashville TN USA Department of Materials Science and Engineering National Tsing Hua University Hsinchu Taiwan

In this study, various thicknesses of Pd catalytic films were deposited on Ti/Si substrates and pretreated with NH/sub 3/. The effects of catalyst deposition parameters and NH/sub 3/ pretreatment time (0, 1, and 10 minutes) on the size distribution of Pd catalytic particles, and subsequently, on the diameter and density of synthesized carbon nanotubes (CNTs) were investigated. The CNTs were synthesized by thermal CVD at 750/spl deg/C using methane (CH/sub 4/) as the carbon source, and a mixture of Ar/H/sub 2/ (80 vol.%/20 vol.%) as the carrier gas.

关键词： Carbon nanotubes Chemical vapor deposition Argon Hydrogen Scanning electron microscopy Morphology Substrates materials science and technology Transmission electron microscopy Carbon dioxide

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Picosecond response of metal-semiconductor-metal ultraviolet phootodiodes

Picosecond response of metal-semiconductor-metal ultraviolet...

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Conference on Lasers and Electro-Optics, CLEO

作者： Li, Jianliang Donaldson, W.R. Hsiang, T.Y. University of Rochester Material Science Program Laboratory for Laser Energetics 250 East River Road Rochester NY 14623 United States Laboratory for Laser Energetics University of Rochester 250 East River Road Rochester NY 14623-1299 United States Department of Electrical and Computer Engineering University of Rochester Rochester NY 14627 United States

We studied the ultrafast response in metal-semiconductor-metal ultraviolet photodiodes fabricated on GaN. The best performance of a device with 1-μmn finger width and spacing showed a 3.5-ps response. The pulse width... 详细信息

关键词： Photodiodes

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Picosecond response of metal-semiconductor-metal ultraviolet photodiodes

Picosecond response of metal-semiconductor-metal ultraviolet...

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Conference on Lasers and Electro-Optics (CLEO)

作者： Jianliang Li W.R. Donaldson T.Y. Hsiang Material Science Program a d olboratory for Laser Energetics University of Rochester Rochester NY USA Laboratory for Laser Energetics University of Rochester Rochester NY USA Department of Electrical and Computer Engineering University of Rochester Rochester NY USA

We studied the ultrafast response in metal-semiconductor-metal ultraviolet photodiodes fabricated on GaN. The best performance of a device with 1-/spl mu/m finger width and spacing showed a 3.5-ps response. The pulse ... 详细信息

ISBN: (纸本)1557527776

关键词： Photodiodes Optical pulse shaping Fingers Energy measurement Gallium nitride Optical devices Ultrafast optics Time measurement Laser theory Rivers

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