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Theoretical study of the transmission properties of a one-dimensional polycarbonate-liquid photonic array

AIP Conference Proceedings 2018年第1期1934卷

作者： A. Sánchez K. Y. Guerra A. V. Porta S. Orozco 1Department of Physics Faculty of Sciences Universidad Nacional Autónoma de México (UNAM) Av. Universidad 3000 col. Universidad Nacional Autónoma de México Cd. De México 04510 México 2Coordination of Ph.D. Program in Materials Science and Engineering Unidad de Posgrado Edificio C 1er. piso cub. 105 Circuito de Posgrados s/n Ciudad Universitaria Cd. de México 04510 México

The opto-fluidics systems can be used for label free refractometric and biosensensing applications. In this work transmission properties of one-dimensional polycarbonate-liquid photonic arrays are studied, where methanol and ethanol were proposed as liquid components. The band structure and the transmission spectrum were calculated using the transference matrix method, in which we consider the dispersion relation for the refractive index n(w) of each material in the visible range. Using lattice parameters of 1 µm, 10 µm, and 4 µm, we obtained forbidden bandgaps in the visible region. When lattice parameters of 1000 µm were considered, we obtained several narrow bandgaps in the visible range.

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development of bionic invasion membrane for the study of multiple sclerosis

Development of bionic invasion membrane for the study of mul...

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IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)

作者： Chia-Yi Lee Kin Fong Lei Cheng-Lung Ku Chia-Hao Huang Ph.D. Program in Biomedical Engineering Chang Gung University Taiwan Department of Mechanical Engineering Chang Gung University Taiwan Graduate Institute of Clinical Medical Science Chang Gung University Taiwan Graduate Institute of Medical Mechatronics Chang Gung University Taiwan

ISBN: (纸本)9781509019489

Multiple sclerosis (MS) is an autoimmune disease and leads to many inflammations. Cause of this disease is autoreactive T cells invade the blood-brain-barrier and attack the myelin sheath. Because MS infringes upon young human and has gradual loss of bodily functions, the disease has a burden on society and economy. Traditional treatment is to use immune-suppressant, but it has many side effects. Currently, the most effective treatment of MS is to use Natalizumab. Target molecule of this agent is α4-integrin of T cells. The mechanism is to prevent invasion of activated lymphocytes across the blood-brain-barrier. However, this agent affects the overall immune response and easily generates side effects of progressive multifocal leukoencephalopathy (PML). Transwall systems are often used to investigate cell invasion, but there is no specific protein immobilizing on the isolation membrane of these systems. In this work, we have successfully developed a bionic invasion membrane for the study of MS. different chemokines were applied to the system for the demonstration of drug screening application. The bionic invasion membrane was a PP/PTEE membrane coated with VCAM-1 protein. Jurkat T cell was used to evaluate the feasibility of using the membrane for the study of MS. Results indicated that the invasion ability of T cells was reduced by VCAM-1 protein. The current work provides bionic invasion membrane for the study of MS in vitro.

关键词： Biomembranes Proteins Multiple sclerosis Immune system Microfluidics Color

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Author Correction: Multi-label deep Learning for Gene Function Annotation in Cancer Pathways

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Scientific reports 2018年第1期8卷 8995页

作者： Renchu Guan Xu Wang Mary Qu Yang Yu Zhang Fengfeng Zhou Chen Yang Yanchun Liang Key Laboratory for Symbol Computation and Knowledge Engineering of National Education Ministry College of Computer Science and Technology Jilin University Changchun 130012 China. MidSouth Bioinformatics Center and Joint Bioinformatics Ph.D. Program of University of Arkansas at Little Rock and Univ. of Arkansas Medical Sciences Little Rock AR 72204 USA. Institute of Information Engineering Chinese Academy of Sciences School of Cyber Security University of Chinese Academy of Sciences Beijing 100093 China. College of Earth Sciences Jilin University Changchun 130061 China. yangc616@***. Key Laboratory for Symbol Computation and Knowledge Engineering of National Education Ministry College of Computer Science and Technology Jilin University Changchun 130012 China. ycliang@***. Zhuhai Laboratory of Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Zhuhai College of Jilin University Zhuhai 519041 China. ycliang@***.

A correction to this article has been published and is linked from the HTML and PdF versions of this paper. The error has not been fixed in the paper.

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Parallel Solution of diagonally dominant Banded Triangular Toeplitz Systems Using Taylor Polynomials

Parallel Solution of Diagonally Dominant Banded Triangular T...

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IEEE International Conference on High Performance Computing and Communications

作者： Michael Kapralos Aron Wolinetz Brian J. Murphy Department of Electrical and Computer Engineering University of Connecticut Storrs CT 06269 The Graduate Center of the City University of New York Ph.D. Program in Computer Science NY NY 10016 Lehman College of the City University of New York Bronx NY 10468

ISBN: (纸本)9781509042982

We present a new numerical and inherently parallel algorithm for solving banded (strictly) diagonally dominant triangular and banded Toeplitz (BddTT) systems of linear equations. A Taylor polynomial, derived from the matrix analog of the Taylor Series for evaluating (1-x) ~(-1)where |χ| < 1, is applied, in conjunction with other techniques, to compute an approximate solution to a BddTT-type system. This method requires O(n log_2n) arithmetic operations (ops) and O(log_2n) parallel steps (steps). Two FFTs and an IFFT of order 2n are the main contributors to the workload. This matches the FFT count for a triangular Toeplitz-matrix-vector multiplication. Clearly then, our method improves on the many algebraic FFT based processes that first determine the triangular Toeplitz matrix that is the inverse of a BddTT matrix in order to then solve the associated BddTT system.

关键词： Banded Triangular Toeplitz diagonally dominant Linear System FFT

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A real-time moving objects detection and classification approach for static cameras

A real-time moving objects detection and classification appr...

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IEEE International Conference on Consumer Electronics-Taiwan (ICCE-TW)

作者： Hong-Son Vu Jia-Xian Guo Kuan-Hung Chen Shu-Jui Hsieh de-Sheng Chen Ph.D. Program of Electrical and Communications Engineering Feng Chia University Taichung Taiwan R.O.C Department of Electronic Engineering Feng Chia University Taichung Taiwan R.O.C Department of Information Engineering and Computer Science Feng Chia University Taichung Taiwan R.O.C

ISBN: (纸本)9781509020744

Moving objects recognition plays an important role in camera-only active safety systems and intelligent autonomous vehicles. For these applications, reliable detection performance is required; however, pedestrian detection is challenging due to their divergent dressing and action variety. Besides, real-time detection and recognition performance is also critical. This paper aims to optimize the pedestrian detection and recognition by combining both temporal-domain and spatial-domain methods. Accordingly, we first use Background Subtraction (BS) technique to detect moving objects. Then, we use AdaBoost algorithm to classify the detected moving objects into their categories. Experimental results on our datasets show that the proposed approach can speed up 3.3 times in terms of processing rate, with significantly improved detection performance, i.e., at least 17% detection rate increment and 38% false alarm decrement for daytime out-door applications.

关键词： Classification algorithms Object detection Real-time systems Object recognition Lighting Training Histograms

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A Hybrid Iterative Approach for Microarray Missing Value Estimation

A Hybrid Iterative Approach for Microarray Missing Value Est...

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IEEE International Conference on Bioinformatics and Biomedicine

作者： Chong He Changbo Zhao Guo-Zheng Li Wei Zhu William Yang Mary Qu Yang Department of Control Science and Engineering Tongji University Shanghai 201804 China Joint Bioinformatics Ph.D. Program. George Washington Donaghey College of Engineering & IT University of Arkansas at Little Rock and University of Arkansas for Medical Sciences 2801 S. University Avenue Little Rock Arkansas 72204 United States

ISBN: (纸本)9781509016129

The completeness of gene expression data is essential to many gene expression data analysis issues. In this paper, inspired by the idea of semi-supervised learning with tri-training, a hybrid iterative imputation method called tri-imputation is proposed to estimate the missing values in gene expression data. In detail, in each round of tri-imputation, any two imputation methods are collaborating with each other to firstly estimate an initial imputation value, and then to be applied to the rest imputation method for providing different available information. Finally, all these three results are combined with their respective pre-trained confidence values. Experimental results on real microarray matrices indicate that tri-imputation achieves more accurate estimation for missing values in terms of the lowest normalized root-mean-square error.

关键词： Hybrid Iterative Approach Microarray Missing Value Estimation providing Finally

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Investigating the main operating mechanism of the zinc oxide layer of ZnO RRAM

Investigating the main operating mechanism of the zinc oxide...

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International Symposium on Computer, Consumer and Control

作者： Xin-tian Zhao Chun-Mei Lu Shao-Wen Su Hsin-Chiang You Cheng-Yen Wu Wen-Luh Yang College of Electrical and Control Engineering Xi'an University of Science and Technology Department of Chemical and Materials Engineering National Chin-Yi University of Technology Department of Applied English National Chin-Yi University of Technology Department of Electronic Engineering National Chin-Yi University of Technology Ph.D. Program of Electrical and Communications Engineering Feng Chia University Department of Electronic Engineering Feng Chia University

ISBN: (纸本)9781509030729

This study is to investigate the main operating mechanism of zinc oxide layer of ZnO RRAM (Resistance Random Access Memory). This experiment prepared four types of ZnO RRAM under different thermal annealing temperatures, Keithley 4200 measurement system was used to measure the operating voltage and current under a high impedance state and a low resistance state into the dielectric layer transmission mechanism analysis. This study found that the operating mechanism of a zinc oxide layer under the low-resistance state is mainly ohm conduction state. However, the operating mechanism of a zinc oxide layer under the high-resistance state is Poole-Frenkel Emission.

关键词： Zinc oxide layer Thermal annealing temperature Ohm conduction Poole - Frank Emission

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From dissemination to Propagation: A New Paradigm for Education developers

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Change 2017年第4期49卷 35-42页

作者： Froyd, Jeffrey E. Henderson, Charles Cole, Renée S. Friedrichsen, debra Khatri, Raina Stanford, Courtney Jeffrey E. Froyd is a Research Professor at Texas A&M University. His research interests include sustained adoption of improvements in learning and teaching systematic reviews in engineering education evaluation of faculty campus climates and assessment of complex learning outcomes. Charles Henderson is a Professor at Western Michigan University with a joint appointment between the Department of Physics and the Mallinson Institute for Science Education. His research focuses on promoting productive changes in higher education at the individual department institution and national levels. Renée S. Cole is an Associate Professor of Chemistry at the University of Iowa. She teaches introductory and advanced courses in chemistry and runs a research program focused on the design and assessment of instructional materials and teaching strategies and faculty professional development. Debra Friedrichsen founded and operates a small consulting company. She received her Ph.D. from Oregon State University in Chemical Engineering with a dissertation focused on engineering education. Debra also has a MBA a MS and a patent for sensor development. Raina Khatri is a doctoral student in the Mallinson Institute for Science Education at Western Michigan University. Her research focus is understanding how education developers in STEM can promote sustained adoption of their innovations. Courtney Stanford is a postdoctoral researcher in the Department of Chemistry at Virginia Commonwealth University. Her current research focuses on the identification development and assessment of process skills (also known as professional skills) in active learning undergraduate STEM classrooms.

Scholarly studies and national reports document failure of current efforts to achieve broad, sustained adoption of research-based instructional practices, despite compelling bodies of evidence supporting efficacy of many of these practices. The authors of this paper argue that many change agents who are working to promote systemic adoption of these teaching practices use approaches that are characterized by what the authors call the "dissemination paradigm." A dissemination paradigm characterizes patterns of these current, failing efforts. Change agents, working within the dissemination paradigm, try to convince adopters that their innovations can help their students. Efforts within the dissemination paradigm have not led, and are unlikely to lead, to systemic adoption. The authors offer the "propagation paradigm" as an alternative with the potential to produce improved results. Change agents, working within the propagation paradigm, engage with adopters early and often to understand their instructional systems and interactively develop a strong product adaptable to specific contexts.

关键词： Models Change Agents Teaching Methods Information dissemination Educational Innovation Instructional Systems STEM Education Comparative Analysis

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Correction: Interface structure, precursor rheology and dielectric properties of BaTiO3/PVdF–hfp nanocomposite films prepared from colloidal perovskite nanoparticles

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RSC Advances 2017年第73期7卷 45987-45987页

作者： Y. N. Hao K. Bi S. O’Brien X. H. Wang J. Lombardi F. Pearsall W. L. Li M. Lei Y. Wu L. T. Li State Key Laboratory of Information Photonics and Optical Communications School of Science Beijing University of Posts and Telecommunications Beijing 100876 China The Department of Chemistry and Biochemistry The City College of New York The Ph.D. Program in Chemistry The Graduate Center of the City University of New York New York NY 10016 USA State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and Engineering Tsinghua University Beijing 100084 China School of Journalism and Communication Beijing Normal University Beijing 100875 China

Correction for ‘Interface structure, precursor rheology and dielectric properties of BaTiO3/PVdF–hfp nanocomposite films prepared from colloidal perovskite nanoparticles’ by Y. N. Hao et al., RSC Adv., 2017, 7, 32...

Correction for ‘Interface structure, precursor rheology and dielectric properties of BaTiO₃/PVdF–hfp nanocomposite films prepared from colloidal perovskite nanoparticles’ by Y. N. Hao et al., RSC Adv., 2017, 7, 32886–32892.

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Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

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Nature communications 2023年第1期14卷 3043页

作者： Jianxin Shi Kouya Shiraishi Jiyeon Choi Keitaro Matsuo Tzu-Yu Chen Juncheng dai Rayjean J Hung Kexin Chen Xiao-Ou Shu Young Tae Kim Maria Teresa Landi dongxin Lin Wei Zheng Zhihua Yin Baosen Zhou Bao Song Jiucun Wang Wei Jie Seow Lei Song I-Shou Chang Wei Hu Li-Hsin Chien Qiuyin Cai Yun-Chul Hong Hee Nam Kim Yi-Long Wu Maria Pik Wong Brian douglas Richardson Karen M Funderburk Shilan Li Tongwu Zhang Charles Breeze Zhaoming Wang Batel Blechter Bryan A Bassig Jin Hee Kim demetrius Albanes Jason Y Y Wong Min-Ho Shin Lap Ping Chung Yang Yang She-Juan An Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young-Chul Kim Neil E Caporaso Jiang Chang James Chung Man Ho Michiaki Kubo Yataro daigo Minsun Song Yukihide Momozawa Yoichiro Kamatani Masashi Kobayashi Kenichi Okubo Takayuki Honda dean H Hosgood Hideo Kunitoh Harsh Patel Shun-Ichi Watanabe Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Hidehito Horinouchi Masahiro Tsuboi Ryuji Hamamoto Koichi Goto Yuichiro Ohe Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Megumi Hara Yuichiro Nishida Kenji Takeuchi Kenji Wakai Koichi Matsuda Yoshinori Murakami Kimihiro Shimizu Hiroyuki Suzuki Motonobu Saito Yoichi Ohtaki Kazumi Tanaka Tangchun Wu Fusheng Wei Hongji dai Mitchell J Machiela Jian Su Yeul Hong Kim In-Jae Oh Victor Ho Fun Lee Gee-Chen Chang Ying-Huang Tsai Kuan-Yu Chen Ming-Shyan Huang Wu-Chou Su Yuh-Min Chen Adeline Seow Jae Yong Park Sun-Seog Kweon Kun-Chieh Chen Yu-Tang Gao Biyun Qian Chen Wu daru Lu Jianjun Liu Ann G Schwartz Richard Houlston Margaret R Spitz Ivan P Gorlov Xifeng Wu Ping Yang Stephen Lam Adonina Tardon Chu Chen Stig E Bojesen Mattias Johansson Angela Risch Heike Bickeböller Bu-Tian Ji H-Erich Wichmann david C Christiani Gadi Rennert Susanne Arnold Paul Brennan James McKay John K Field Sanjay S Shete Loic Le Marchand Geoffrey Liu Angeline Andrew Lambertus A Kiemeney Shan Zienolddiny-Narui Kjell Grankvist Mikael Johansson Angela Cox Fiona Taylor Jian-Min Yuan philip Lazarus Matthew B Schabath Melinda C Aldrich Hyo-Sung Jeon Shih Sheng Jiang Jae Sook Sung C Division of Cancer Epidemiology and Genetics National Cancer Institute Rockville MD USA. jianxin.shi@nih.gov. Division of Genome Biology National Cancer Research Institute Tokyo Japan. Division of Cancer Epidemiology and Genetics National Cancer Institute Rockville MD USA. Division of Cancer Epidemiology and Prevention Aichi Cancer Center Research Institute Nagoya Japan. Institute of Population Health Sciences National Health Research Institutes Zhunan Taiwan. Department of Epidemiology School of Public Health Nanjing Medical University Nanjing China. Jiangsu Key Lab of Cancer Biomarkers Prevention and Treatment Collaborative Innovation Center for Cancer Medicine Nanjing Medical University Nanjing China. Prosserman Centre for Population Health Research Lunenfeld-Tanenbaum Research Institute Sinai Health Toronto ON Canada. Department of Epidemiology and Biostatistics National Clinical Research Center for Cancer Key Laboratory of Molecular Cancer Epidemiology of Tianjin Tianjin Medical University Cancer Institute and Hospital Tianjin Medical University Tianjin China. Division of Epidemiology Department of Medicine Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center Nashville TN USA. Cancer Research Institute Seoul National University College of Medicine Seoul Republic of Korea. Department of Etiology & Carcinogenesis and State Key Laboratory of Molecular Oncology Cancer Institute and Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China. Department of Epidemiology School of Public Health China Medical University Shenyang China. Department of Clinical Epidemiology and Center of Evidence Based Medicine The First Hospital of China Medical University Shenyang China. Department of Oncology Shandong Cancer Hospital and Institute Shandong Academy of Medical Sciences Jinan China. Ministry of Education Key Laboratory of Contemporary Anthropology School of Life Sciences Fudan University Shanghai China. S

Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study of lung adenocarcinoma of East Asian ancestry (21,658 cases and 150,676 controls; 54.5% never-smokers) and identified 12 novel susceptibility variants, bringing the total number to 28 at 25 independent loci. Transcriptome-wide association analyses together with colocalization studies using a Taiwanese lung expression quantitative trait loci dataset (n = 115) identified novel candidate genes, including FAdS1 at 11q12 and ELF5 at 11p13. In a multi-ancestry meta-analysis of East Asian and European studies, four loci were identified at 2p11, 4q32, 16q23, and 18q12. At the same time, most of our findings in East Asian populations showed no evidence of association in European populations. In our studies drawn from East Asian populations, a polygenic risk score based on the 25 loci had a stronger association in never-smokers vs. individuals with a history of smoking (P = 0.0058). These findings provide new insights into the etiology of lung adenocarcinoma in individuals from East Asian populations, which could be important in developing translational applications.

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