检索结果-内蒙古大学图书馆

Preparation,characterization and in vitro/in vivo evaluations of paclitaxel-loaded micelles based on a-tocopherol succinate-modified chitosan

Preparation,characterization and in vitro/in vivo evaluation...

引用

2015年中国药物制剂大会暨中国药学会药剂专业委员会2015年学术年会暨国际释控协会中国分会2015年学术年会

作者：孙少平 Na Liang Pengfei Yan Qiang Li Xianfeng Gong School of Chemistry and Material Science Heilongjiang University Key Laboratory of Chemical Engineering Process & Technology for High-efficiency Conversion College of Heilongjiang Province College of Chemistry & Chemical Engineering Harbin Normal University

α-tocopherol succinate modified chitosan（CS-TOS）was synthesized by coupling *** formation of CS-TOS was confirmed byH-NMR and FT-IR *** aqueous medium,the polymer could self-aggregate to form micelles,and the critical micelle concentration（CMC）was determined to be5.8×10mg/*** was then encapsulated into micelles by a probe-type ultrasonic method.

关键词： PTX Taxol Preparation,characterization and in vitro/in vivo evaluations of paclitaxel-loaded micelles based on a-tocopherol succinate-modified chitosan

来源：评论

学校读者我要写书评

暂无评论

Validation of precision powder injection molding process simulations using a spiral test geometry

引用

AIP Conference Proceedings 2016年第1期1779卷

作者： Maximilian Marhöfer Tobias Müller Guido Tosello Aminul Islam Hans N. Hansen Volker Piotter Department of Mechanical Engineering Technical University of Denmark Produktionstorvet Building 427A 2800 Kongens Lyngby Denmark Karlsruhe Institute of Technology Institute for Applied Materials – Material Process Technology Hermann-von-Helmholtz-Platz 1 76344 Eggenstein-Leopoldshafen Germany

Like in many other areas of engineering, process simulations find application in precision injection molding to assist and optimize the quality and design of precise products and the molding process. Injection molding comprises mainly the manufacturing of plastic components. However, the variant of precision powder injection molding for the production of metallic and ceramic micro parts raises more and more interest though. Consequently, in the entire field the demand for simulation tools increases constantly, too. The present work reports the material characterization of feedstocks which are used for powder injection molding. This characterization includes measurements of rheological, thermal, and pvT behavior of the powder-binder-mixes. The acquired material data was used to generate new material models for the database of the commercially available Autodesk Moldflow® simulation software. The necessary data and the implementation procedure of the new material models are outlined. In order to validate the simulation studies and evaluate their accuracy, the simulation results are compared with experiments performed using a spiral test geometry.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Effect of work of adhesion on deep bed filtration process

引用

AIP Conference Proceedings 2016年第1期1738卷

作者： Rafał Przekop Anna Jackiewicz Michał Wożniak Leon Gradoń aWarsaw University of Technology Faculty of Chemical and Process Engineering Ul. Waryńskiego 1 00-645 Warsaw Poland bWarsaw University of Technology Faculty of Material Science and Engineering Ul. Wołoska 141 02-507 Warsaw Poland cWarsaw University of Technology University Research Centre Functional Materials Ul. Wołoska 141 02-507 Warsaw Poland

Collection of aerosol particles in the particular steps of the technology of their production, and purification of the air at the workplace and atmospheric environment, requires the efficient method of separation of particulate matter from the carrier gas. There are many papers published in last few years in which the deposition of particles on fibrous collectors is considered, Most of them assume that collisions between particle and collector surface is 100% effective. In this work we study the influence of particles and fiber properties on the deposition efficiency. For the purpose of this work the lattice-Boltzmann model describes fluid dynamics, while the solid particle motion is modeled by the Brownian dynamics. The interactions between particles and surface are modelled using energy balanced oscillatory model. The work of adhesion was estimated using Atomic Force Microscopy.

关键词：

来源：评论

学校读者我要写书评

暂无评论

NEXAFS and XPS of p-Aminobenzoic Acid Polymorphs: The Influence of Local Environment

引用

Journal of Physics: Conference Series 2016年第1期712卷

作者： J S Stevens A Gainar C Jaye D A Fischer S L M Schroeder School of Chemical Engineering and Analytical Science The University of Manchester Oxford Road Manchester M13 9PL UK Material Measurement Laboratory National Institute of Standards and Technology Gaithersburg MD 20899 USA School of Chemical and Process Engineering University of Leeds Leeds LS2 9JT UK DIAMOND Light Source Ltd. Chilton Didcot OX11 0QX UK

Nitrogen K-edge XPS and NEXAFS of the two polymorphic forms of para- aminobenzoic acid (PABA) are significantly different reflecting variation in hydrogen bonding. Alteration in hydrogen bonding at the amino group leads to a shift to high energy for both the XPS N 1s core level and the 3π* NEXAFS resonance with β-PABA. Participation of the amine group in the aromatic system causes the 1π* resonance to be sensitive to the nature of the intermolecular bonding at the para-carboxylic acid group, and a shift to low energy for α- PABA is observed due to hydrogen-bonded carboxylic acid dimer formation. FEFF calculations also successfully reproduce both the energy and intensity variations observed for the σ* shape resonance associated with the C-N bond, with the majority of the decrease in energy observed for b-PABA arising from the longer C-N bond.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Targeted Drug Delivery: Carbon-Quantum-Dots-Loaded Mesoporous Silica Nanocarriers with pH-Switchable Zwitterionic Surface and Enzyme-Responsive Pore-Cap for Targeted Imaging and Drug Delivery to Tumor (Adv. Healthcare Mater. 12/2016).

引用

Advanced healthcare materials 2016年第12期5卷

作者： Zhongning Liu Xin Chen Xiaojin Zhang John Justin Gooding Yongsheng Zhou Department of Prosthodontics Peking University School and Hospital of Stomatology Beijing 100081 China. School of Chemical Engineering and Technology Shanxi Key Laboratory of Energy Chemical Process Intensification Xi'an Jiaotong University Xi'an 710049 China. Key Laboratory of Biomedical Polymers of Ministry of Education Department of Chemistry Wuhan University Wuhan 430072 China. School of Chemistry and Australian Centre for NanoMedicine University of New South Wales Sydney 2052 Australia. Department of Prosthodontics National Engineering Lab for Digital and Material Technology of Stomatology Peking University School and Hospital of Stomatology Beijing 100081 China.

On page 1401 X. Chen, X. Zhang, Y. Zhou, and co-workers describe the synthesis of mesoporous silica nanocarriers with pH-switchable antifouling zwitterionic surfaces and blue fluorescence that are capable of enzyme-responsive drug release. The system combines tumor treatment and tracking. It shows great potential for cancer treatment, since it exhibits prolonged circulation in the blood system with zero premature release while offering selective cellular uptake, tumor labeling, and intracellular drug release in tumor tissue.

关键词： dual-stimuli responsiveness mesoporous silica nanocarriers selective cell imaging switchable antifouling tumor targeting drug delivery

来源：评论

学校读者我要写书评

暂无评论

SolarSyngas: Results from a virtual institute developing materials and key components for solar thermochemical fuel production

引用

AIP Conference Proceedings 2016年第1期1734卷

作者： Martin Roeb Aldo Steinfeld Günter Borchardt Claus Feldmann Martin Schmücker Christian Sattler Robert Pitz-Paal 1German Aerospace Center (DLR) Institute of Solar Research 51147 Köln Germany 2ETH Zurich Department of Mechanical and Process Engineering 8092 Zurich Switzerland 3Technical University Clausthal Institute of Metallurgy 38678 Clausthal Germany 4Karlsruhe Institute of Technology (KIT) Institute of Inorganic Chemistry 76131 Karlsruhe Germany 5German Aerospace Center (DLR) Institute of Material Research 51147 Köln Germany

The Helmholtz Virtual Institute (VI) SolarSynGas brings together expertise from solar energy research and materials science to develop metal oxide based redox materials and to integrate them in a suitable way into related process technologies for two-step thermochemical production of hydrogen and carbon monoxide from water and CO2. One of the foci of experimental investigation was exploring the impact of doping on the feasibility of ceria-based materials – mainly by Zr-doping. The results indicate that a certain Zr-content enhances the reducibility and therefore the splitting performance. Increasing the Zr-content to x = 0.15 improved the specific CO2-splitting performance by 50% compared to pure ceria. This finding agrees with theoretical studies attributing the improvements to lattice modification caused by the introduction of Zr4+. Thermogravimetric relaxation experiments and equilibrium oxygen isotope exchange experiments with subsequent depth profiling analysis were carried out on ceria. As a result the reduction reaction of even dense samples of pure ceria with a grain size of about 20 µm is surface reaction controlled. The structure of the derived expression for the apparent activation energy suggests that the chemical surface exchange coefficient should show only a very weak dependence on temperature for ceria doped with lower valence cations. A solar receiver reactor exhibiting a foam-type reticulated porous ceramics made of ceria was tested. It could be shown that applying dual-scale porosity to those foams with mm-size pores for effective radiative heat transfer during reduction and μm-size pores within its struts for enhanced kinetics during oxidation allows enhancing the performance of the reactor significantly. Also a particle process concept applying solid-solid heat recovery from redox particles in a high temperature solar thermochemical process was analysed that uses ceramic spheres as solid heat transfer medium. This concept can be implemented into

关键词：

来源：评论

学校读者我要写书评

暂无评论

Durability research of magnesium chloride hexahvgrate as a promising PCM for solar energy storage under medium temperature through thermal cycles

引用

Gongneng Cailiao/Journal of Functional materials 2014年第9期45卷 09127-09131页

作者： Li, Wen-Hao Xu, Ling-Ling College of Material Science and Engineering Nanjing University of Technology Nanjing 210009 China Jiangsu Key Laboratory of Process Enhancement and New Energy Equipment Technology Nanjing University of Technology Nanjing 210009 China

In order to study the feasibility of magnesium chloride hexahvgrate(MgCl2·6H2O) as a PCM under medium temperature, six hundred accelerated thermal cycle tests had been conducted under sealed and unsealed conditions. The melting temperature and the latent heat of fusion, crystalline structure and degree of supercooling were determined by differential scaning calorimetry (DSC), X-ray diffraction (XRD) and multiway temperature detector respectively. The results indicated that the decrease in latent heat of fusion of MgCl2·6H2O under unsealed condition was 54.2% and accompanied with a new phase MgCl2·4H2O after 200 cycles. The change in melting temperature, peak temperature of MgCl2·6H2O under sealed condition was ±1% and ±4% respectively, and the change in latent heat of fusion was and -15.2%-+1.5% except for the 300th melt/freeze cycle. MgCl2·6H2O solidified with a slight degree of supercooling in the range 0-2.2°C. It was indicated that MgCl2·6H2O under sealed condition was a promising phase change material for solar energy use under medium temperature.

关键词： Magnesium compounds

来源：评论

学校读者我要写书评

暂无评论

Casimir quantum levitation tuned by means of material properties and geometries

引用

Physical Review B 2014年第20期89卷 201407(R)-201407(R)页

作者： Maofeng Dou Fei Lou Mathias Boström Iver Brevik Clas Persson Department of Materials Science and Engineering Royal Institute of Technology SE-100 44 Stockholm Sweden Laboratory of Photonics and Microwave Engineering KTH-Royal Institute of Technology SE-164 40 Kista Sweden Department of Energy and Process Engineering Norwegian University of Science and Technology NO-7491 Trondheim Norway Centre for Material Science and Nanotechnology University of Oslo P.O. Box 1048 Blindern NO-0316 Oslo Norway Department of Physics University of Oslo P.O. Box 1048 Blindern NO-0316 Oslo Norway

The Casimir force between two surfaces is attractive in most cases. Although stable suspension of nano-objects has been achieved, the sophisticated geometries make them difficult to be merged with well-established thin film processes. We find that by introducing thin film surface coating on porous substrates, a repulsive to attractive force transition is achieved when the separations are increased in planar geometries, resulting in a stable suspension of two surfaces near the force transition separation. Both the magnitude of the force and the transition distance can be flexibly tailored though modifying the properties of the considered materials, that is, thin film thickness, doping concentration, and porosity. This stable suspension can be used to design new nanodevices with ultralow friction. Moreover, it might be convenient to merge this thin film coating approach with micro- and nanofabrication processes in the future.

关键词： CASIMIR effect QUANTUM field theory POROSITY THIN films FRICTION

来源：评论

学校读者我要写书评

暂无评论

Dependence of the abnormal protective property on the corrosion product film formed on H2S-adjacent API-X52 pipeline steel

Dependence of the abnormal protective property on the corros...

引用

作者： Zheng, Shuqi Zhou, Chengshuang Chen, Xingyang Zhang, Lin Zheng, Jinyang Zhao, Yongzhi State Key Laboratory of Heavy Oil Processing Department of Materials Science and Engineering China University of Petroleum Beijing 102249 China Institute of Material Forming and Control Engineering College of Materials Science and Engineering Zhejiang University of Technology Hangzhou 310014 China Institute of Process Equipment Zhejiang University Hangzhou 310027 China

The dependence of the protective property on the corrosion product film formed on API-X52 pipeline steel was investigated using the electro-chemical hydrogen permeation method in acidic solution under various H2S partial pressures. The hydrogen permeation current is dependent on the H 2S concentration and the corrosion product film. The hydrogen permeation current increases with the H2S partial pressure, and decreases with thickening the corrosion product film. The dense corrosion product films formed in 1.0 MPa H2S shows the obvious protective property against hydrogen permeation, while the delamination of the corrosion product film formed in 0.1 MPa H2S weakens the protective property. The hydrogen permeation current in 1.0 MPa H2S is lower than that in 0.1 MPa H2S after 200 h immersion in acidic solution and this is of great significance to the service life prediction and the prevention of hydrogen embrittlement in H2S-adjacent pipelines. © 2014, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.

关键词： Steel pipe

来源：评论

学校读者我要写书评

暂无评论

Hydrogen Effects on Nanoindentation Creep of Austenitic Stainless Steels

Hydrogen Effects on Nanoindentation Creep of Austenitic Stai...

引用

第十五届全国氢能会议暨第7届两岸三地氢能研讨会

作者： Lin ZHANG Chengshuang ZHOU Jinyang ZHENG Yongzhi ZHAO Chaohua GU Chilou ZHOU Zhengli HUA Xingyang CHEN Institute of Process Equipment Zhejiang UniversityHangzhou 310027China Institute of Material Forming and Control Engineering Zhejiang University of TechnologyHangzhou 310014

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：