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Fully implantable and battery-free wireless optoelectronic system for modulable cancer therapy and real-time monitoring

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npj Flexible Electronics 2023年第1期7卷 119-130页

作者： Kiho Kim In Sik Min Tae Hee Kim Do Hyeon Kim Seungwon Hwang Kyowon Kang Kyubeen Kim Sangun Park Jongmin Lee Young Uk Cho Jung Woo Lee Woon-Hong Yeo Young Min Song Youngmee Jung Ki Jun Yu Functional Bio-integrated Electronics and Energy Management Lab School of Electrical and Electronic EngineeringYonsei University50 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea Center for Biomaterials Biomedical Research InstituteKorea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Department of Fusion Research and Collaboration Biomedical Research InstituteSeoul National University HospitalSeoul 03080Republic of Korea School of Electrical Engineering and Computer Science(EECS) Gwangju Institute of Science and Technology(GIST)Gwangju 61005Republic of Korea PA1 Foundry BusinessSamsung Electronics1 Samsungjeonja-roHwaseong-siGyeonggi-doRepublic of Korea R&D Center DNA Lab PharmaresearchSeongnam 13486Republic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul 136-705Republic of Korea School of Materials Science and Engineering Energy Materials for Soft Electronics LaboratoryPusan National UniversityBusan 46241Republic of Korea IEN Center for Human-Centric Interfaces and Engineering and George W.Woodruff School of Mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Wallace H.Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University School of MedicineAtlantaGA 30332USA Institute for Robotics and Intelligent Machines Parker H.Petit Institute for Bioengineering and BiosciencesInstitute for MaterialsNeural Engineering CenterGeorgia Institute of TechnologyAtlantaGA 30332USA School of Electrical and Electronic Engineering YU-Korea Institute of Science and Technology(KIST)InstituteYonsei University50Yonsei-roSeodaemun-guSeoul 03722Republic of Korea

Photodynamic therapy(PDT)is attracting attention as a next-generation cancer treatment that can selectively destroy malignant tissues,exhibit fewer side effects,and lack pain during *** PDT systems have recently been developed to resolve the issues of bulky and expensive conventional PDT systems and to implement continuous and repetitive *** implantable PDT systems,however,are not able to perform multiple functions simultaneously,such as modulating light intensity,measuring,and transmitting tumor-related data,resulting in the complexity of cancer ***,we introduce a flexible and fully implantable wireless optoelectronic system capable of continuous and effective cancer treatment by fusing PDT and hyperthermia and enabling tumor size monitoring in *** system exploits micro inorganic light-emitting diodes(μ-LED)that emit light with a wavelength of 624 nm,designed not to affect surrounding normal tissues by utilizing a fully programmable light intensity ofμ-LED and precisely monitoring the tumor size by Si phototransistor during a long-term implantation(2–3 weeks).The superiority of simultaneous cancer treatment and tumor size monitoring capabilities of our system operated by wireless power and data transmissions with a cell phone was confirmed through in vitro experiments,ray-tracing simulation results,and a tumor xenograft mouse model in *** all-in-one single system for cancer treatment offers opportunities to not only enable effective treatment of tumors located deep in the tissue but also enable precise and continuous monitoring of tumor size in real-time.

关键词： optoelectronic enable battery

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Leveraging Voltage-Controlled Magnetic Anisotropy to Solve Sneak Path Issues in Crossbar Arrays

arXiv

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arXiv 2022年

作者： Yang, Kezhou Sengupta, Abhronil The Department of Materials Science and Engineering School of Electrical Engineering and Computer Science The Pennsylvania State University University ParkPA16802 United States

In crossbar array structures, which serves as an "In-Memory" compute engine for Artificial Intelligence hardware, write sneak path problem causes undesired switching of devices that degrades network accuracy. While custom crossbar programming schemes have been proposed, device level innovations leveraging non-linear switching characteristics of the crosspoint devices are still under exploration to improve the energy efficiency of the write process. In this work, a spintronic device design based on Magnetic Tunnel Junction (MTJ) exploiting the use of voltage-controlled magnetic anisotropy (VCMA) effect is proposed as a solution to the write sneak path problem. Additionally, insights are provided regarding appropriate operating voltage conditions to preserve the robustness of the magnetization trajectory during switching which is critical for proper switching probability manipulation. © 2022, CC BY.

关键词： Magnetic anisotropy

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Solid High-Speed Synchronous Reluctance Rotor Enabled by Multi-Material Additive Manufacturing

Solid High-Speed Synchronous Reluctance Rotor Enabled by Mul...

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IEEE Energy Conversion Congress and Exposition, ECCE

作者： Dante Newman Patrick Faue FNU Nishanth Behzad Rankouhi Frank E. Pfefferkorn Dan J. Thoma Eric Severson Department of Electrical and Computer Engineering University of Wisconsin-Madison Madison WI USA Department of Mechanical Engineering University of Wisconsin-Madison Madison WI USA Department of Materials Science and Engineering University of Wisconsin-Madison Madison WI USA

Synchronous reluctance (SynR) motor technology is promising to realize rare-earth material-free electric machines. However, structural challenges limit operation speed and subsequently power density compared to machines with rare-earth permanent magnets. This paper proposes and investigates multi-material additive manufacturing (MMAM) as a key-enabler to realize power-dense SynR machines. It does so by guiding magnetic flux through a solid rotor component by selective placement of magnetic and non-magnetic materials to enable high-speed operation. To validate this concept, samples are manufactured using a MMAM process and experimentally characterized to assess the structural and magnetic properties that can be expected for the proposed rotors. The data is then used in a multi-physics modeling framework to explore the design space of new MMAM rotor concepts. The simulated results in this paper reveal that MMAM technology can enable a 4x increase in rotor speed, resulting in 400 % power density improvements. The MMAM rotors achieved tip speeds of approximately 300 m/s and rotational speeds over 55 kRPM at comparable efficiencies to conventional designs, despite the presence of existing MMAM geometry restrictions. This study ultimately demonstrates that MMAM technology has the potential to enhance SynR machine operation speed and power density, making it a valuable option for high-performance applications.

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Charge carrier dynamics in different crystal phases of CH_(3)NH_(3)PbI_(3)perovskite

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Opto-Electronic science 2022年第4期1卷 1-10,22-27页

作者： Efthymis Serpetzoglou Ioannis Konidakis George Kourmoulakis Ioanna Demeridou Konstantinos Chatzimanolis Christos Zervos George Kioseoglou Emmanuel Kymakis Emmanuel Stratakis Institute of Electronic Structure and Laser(IESL) Foundation for Research and Technology-Hellas(FORTH)Herakleio 70013Greece Electrical and Computer Engineering Department Hellenic Mediterranean UniversityHerakleio 71004Greece Department of Materials Science and Technology University of CreteHerakleio 70013Greece Department of Physics University of CreteHerakleio 70013Greece.

Despite that organic-inorganic lead halide perovskites have attracted enormous scientific attention for energy conversion applications over the recent years,the influence of temperature and the type of the employed hole transport layer(HTL)on the charge carrier dynamics and recombination processes in perovskite photovoltaic devices is still largely *** particular,significant knowledge is missing on how these crucial parameters for radiative and non-radiative recombinations,as well as for efficient charge extraction vary among different perovskite crystalline phases that are induced by temperature ***,we perform micro photoluminescence(pPL)and ultrafast time resolved transient absorption spectroscopy(TAS)in Glass/Perovskite and two dierent Glass/ITO/HTL/Perovskite configurations at temperatures below room temperature,in order to probe the charge carrier dynamics of different perovskite crystalline phases,while considering also the effect of the employed HTL ***,CH_(3)NH_(3)Pbb films were deposited on Glass,PEDOT:PSS and PTAA polymers,and the developed Glass/CH_(3)NH_(3)PbI_(3)and Glass/ITO/HTL/CH_(3)NH_(3)PbI_(3)architectures were studied from 85 K up to 215 K in order to explore the charge extraction dynamics of the CH_(3)NH_(3)PbI_(3)orthorhombic and tetragonal crystalline *** is observed an unusual blueshift of the bandgap with temperature and the dual emission at temperature below of 100 K and also,that the charge carrier dynamics,as expressed by hole injection times and free carrier recombination rates,are strongly depended on the actual pervoskite crystal phase,as well as,from the selected hole transport material.

关键词： transient absorption spectroscopy p-photoluminescence variable temperature perovskite crystalline phases hole transport layer charge carrier dynamics

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Special issue on the 100^(th) anniversary of Xiamen University

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Light(science & Applications) 2021年第10期10卷 1812-1813页

作者： Junyong Kang Minghui Hong Zhongqun Tian Engineering Research Center of Micro-nano Optoelectronic Materials and Devices Ministry of EducationFujian Key Laboratory of Semiconductor Materials and ApplicationsCI center for OSEDCollege of Physical Science and Technology361005 XiamenChina Department of Electrical and Computer Engineering National University of Singapore4 Engineering Drive 3117576 SingaporeSingapore State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy MaterialsCollege of Chemistry and Chemical EngineeringXiamen University361005 XiamenChina

This special issue is devoted to the celebration of the century anniversary of Xiamen University(XMU)(6 April 2021)and the establishment of the LSA Editorial Office in Xiamen(3 July 2021),a collection to highlight the recent exciting research works performed in XMU or by XMU alumni,from all aspects of optics and photonics,including basic,applied and engineering research and *** guest editors are three XMU alumni who are active researchers in these areas:Professor Minghui Hong from National University of Singapore,Professor Zhongqun Tian and Professor Junyong Kang from XMU.

关键词： Xiamen anniversary devoted

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An Empirical Generation Technique on Background Music Using Gated Recurrent Neural Networks

An Empirical Generation Technique on Background Music Using ...

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IEEE International Conference on Consumer Electronics-Taiwan (ICCE-TW)

作者： Varinya Phanichraksaphong Wei-Ho Tsai International Graduate Program of Electrical Engineering and Computer Science (IEECS) National Taipei University of Technology Taipei Taiwan Department of Electronic Engineering National Taipei University of Technology Taipei Taiwan

The implementation of Gated Recurrent Neural Networks (GRU) to generate background music (BGM) combines deep learning technology with music that is used for the visual content of a commercial or educational. Indeed, this BGM is necessary to enhance the intended message expressed to the other audience. This work aimed to provide the model network of GRU which is based on RNN to generate multi-label genres of music by using the open source of GTZAN to evaluate the new BGM. Our GRU networks can solve the vanishing gradient problem by utilizing both the reset gate and the update gate on the network. In the results, we achieved a new BGM that synchronized with the human mood which made more variety of sounds.

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Design of high-entropy films as ultra-violet light reflector

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Applied materials Today 2024年 36卷

作者： Yeh, Cheng-Hsien You, Hau-Shiang Chang, Yuan-Chun Kuan, Chen-Yun Wu, Hsuan-Ta Hsu, Wen-Dung Shih, Chuan-Feng Department of Electrical Engineering National Cheng Kung University Tainan70101 Taiwan Department of Materials Science and Engineering National Cheng Kung University Tainan70101 Taiwan Department and Institute of Electrical Engineering Minghsin University of Science and Technology Hsinchu30401 Taiwan Program on Semiconductor Packaging and Testing Academy of Innovative semiconductor and Sustainable Manufacture National Cheng Kung University Tainan70101 Taiwan Center National Cheng Kung University Tainan70101 Taiwan

This study proposes the design and implementation of high-entropy alloy (HEA) thin films as materials for the reflector of deep ultraviolet light-emitting devices and marks the first application of HEA in optical field. In the material design phase, an Al-Co-Zn-Ni alloy is designed by considering the reflectivity, phase stability and binary formation energy. Reverse Monte Carlo calculation is employed to establish stable atomic structure. Frequency-dependent dielectric equations are derived from first principles calculations, with dielectric constants incorporating contributions from ions and electrons and combining classical Drude and Lorentz models. The dielectric equations yield optical constants that are used to calculate the reflectance. In the experimental phase, we systematically vary the aluminum content and prepare Al-Co-Zn-Ni thin films ranging from pure aluminum to equimolar compositions. In the deep ultraviolet region, the reflectance of thermally treated Al65Zn12Co12Ni11 and Al50Zn16Co17Ni17 thin films is found superior to that of gold by three times. Structural and crystalline changes with varying aluminum content are found, as well as intriguing phase separation and superlattice formation that persist until equimolar compositions. This unique nanoscale structural variation causes the Young's modulus and hardness of Al-Co-Zn-Ni thin films to initially increase and then decrease with decreasing aluminum content. There is a significant increase in the corrosion potential difference when reducing Al contents in Al-Co-Zn-Ni, indicating improved passivation effects as the equimolar composition is approached. By modulating the aluminum content, the nanoscale structure of Al-Co-Zn-Ni can be adjusted, thereby improving its optical, mechanical, corrosion resistance, and thermal stability properties. This demonstrates the high versatility of this material for practical optical applications. © 2023

关键词： Zinc alloys

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materials Design for Charge-programmed Additive Manufacturing of Antennas

Materials Design for Charge-Programmed Additive Manufacturin...

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Antennas and Propagation Society International Symposium

作者： Zhen Wang Zhenpeng Xu Junbo Wang Ryan Hensleigh Yahya Rahmat-Samii Xiaoyu Rayne Zheng Department of Materials Science & Engineering University of California Berkeley CA USA Department of Civil and Environmental Engineering University of California Los Angeles CA USA Department of Electrical and Computer Engineering University of California Los Angeles CA USA

Antennas fabricated with traditional manufacturing methods typically carry redundant weight and are limited in 3D architecture complexity. Current additive manufacturing (AM) methods also lacks the capability to construct antennas with multiple materials. The charge-programmed multi-material AM process demonstrated in this work allows the design and manufacturing of antennas with previously unattainable mechanical properties. In this paper, we discuss the principles behind the multi-material printing and the versatility of the selective metal deposition process. We also introduce the material designs that enables the variation of material property, which makes it possible to print both stiff and flexible antennas.

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Observation of Su-Schrieffer-Heeger Topological Model Band Structure in Integrated LNOI Coupled Ring Cavities 16

Observation of Su-Schrieffer-Heeger Topological Model Band S...

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16th Pacific Rim Conference on Lasers and Electro-Optics, CLEO-PR 2024

作者： Dinh, Hiep X. Balcytis, Armandas Ozawa, Tomoki Ota, Yasutomo Baba, Toshihiko Iwamoto, Satoshi Mitchell, Arnan Nguyen, Thach G. Rmit University Integrated Photonics and Applications Centre MelbourneVIC3000 Australia Advanced Institute for Materials Research Tohoku University Sendai980-8577 Japan Keio University Department of Applied Physics and Physico-Informatics Yokohama223-8522 Japan Yokohama National University Department of Electrical and Computer Engineering Yokohama240-8501 Japan The University of Tokyo Research Center for Advanced Science and Technology Tokyo153-8904 Japan

We report synthetic frequency dimension Su-Schrieffer-Heeger model and its band structure observation using coupled ring cavities on an integrated photonic chip. Intra-cell and inter-cell couplings between hybridized ... 详细信息

ISBN: (纸本)9798350372076

关键词： Photonic integrated circuits

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Q-Learning-Based Multi-Objective Global Path Planning for UGV Navigation*

Q-Learning-Based Multi-Objective Global Path Planning for UG...

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IEEE Latin American Robotics Symposium, LARS

作者： Hiago O. B. Batista Thayron M. Hudson Kevin B. de Carvalho Alexandre S. Brandão Department of Electrical Engineering Graduate Program in Computer Science Núcleo de Especialização em Robótica (NERo) Universidade Federal de Viçosa Viçosa - MG Brazil

ISBN: (数字)9798331508807

ISBN: (纸本)9798331508814

This paper presents an offline path planning strategy for unmanned ground vehicles (UGVs) using Q-learning. The proposed method addresses path optimization in warehouse-like environments, where tasks involve item pickup and delivery to specific locations. The Q-learning algorithm trains an agent to determine the most efficient routes, with validation conducted in an $8 \times 5$ meter workspace equipped with an Optitrack motion capture system. The workspace was discretized into a $16 \times 10$ grid, allowing the Q-learning to effectively navigate through complex obstacle-laden scenarios. Experimental results indicate that the Q-learning approach outperforms traditional methods such as Dijkstra, A-star, and Breadth-First Search in terms of path length, number of turns, planning time, and overall success rate; being up to 7 times faster to plan a path and reducing the number of bends by up to 41%. The Q-learning based paths feature more linear segments, which contribute to energy savings and improved navigational efficiency. Future work will explore applications in heterogeneous multi-agent systems and enhancements in training time and agent collaboration.

关键词： Training Meters Q-learning Navigation Path planning Motion capture Planning Robots Optimization Multi-agent systems

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