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Injectable Platelet-Rich Fibrin in Contact with Bone Substitutes, Porous Zirconia, or Laser-Textured Implant Surfaces: A Detailed Morphological Analysis

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Biomedical Materials and Devices 2024年第1期2卷 415-426页

作者： Oliveira, Miguel Noronha Varela, Hugo Almeida Nascimento, Rubens M. Sahoo, Narayan Carvalho, Oscar Henriques, Bruno Souza, Júlio C. M. Ceramic and Composite Materials Research Group (CERMAT) Department of Mechanical Engineering (EMC) Federal University of Santa Catarina (UFSC) Post-graduate Program in Materials Science and Engineering Federal University of Rio Grande Norte (UFRN) Center for MicroElectroMechanical Systems (CMEMS-UMINHO) Universidade do Minho LABBELS - Associate Laboratory University of Minho University Institute of Health Sciences (IUCS) CESPU

The aim of the present study was to perform a detailed morphological analysis of an injectable platelet rich fibrin after combination with two different particulate hydroxyapatite-based granules, a porous zirconia block, and laser-textured zirconia or titanium surfaces. Blood samples were harvested from three participants to prepare the flowable injectable PRF in contact or not with particulate hydroxyapatite (Hap), bone mineral granules (DBBM), porous zirconia blocks, laser-textured titanium or zirconia surfaces. Optical and scanning electron microscopy (SEM) were used to evaluate the fibrin network density, fibrin fibers’ diameter, blood cells, and the interaction of PRF with the biomaterials. Histomorphometry of the flowable PRF was also performed using the hematoxylin–eosin staining protocol. Specimens were independently evaluated by two blinded and well-trained researchers in histomorphometry and microscopy. Particulate Hap and DBBM shown different morphological aspects by SEM analyses since DBBM revealed macro- and micro-scale pores while Hap revealed a dense structure. Hydroxyapatite and DBBM granules were entirely embedded by the fibrin-network in the presence of leukocytes and blood platelets. The zirconia porous structured was filled with PRF and its components. Also, the laser-structured zirconia or implant surfaces were entirely coated with the PRF fibrin network embedding leukocytes and blood platelets. Laser-textured titanium surfaces revealed macro- and micro-scale irregularities that increase the surface area and retention of the injectable PRF. Histomorphometric analyses revealed complementary details on the distribution of lymphocytes, red blood cells, and fibrin associated with platelet aggregation. The flowing and viscosity of an injectable platelet rich fibrin provided an agglomeration of synthetic or xenogeneic particulate bone substitutes and the coating of porous zirconia and textured implant surfaces as inspected by scanning electron microsc

关键词： Bone healing Bone substitutes Histology Morphology Platelet-rich fibrin

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Particle-based Instance-aware Semantic Occupancy Mapping in Dynamic Environments

arXiv

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arXiv 2024年

作者： Chen, Gang Wang, Zhaoying Dong, Wei Alonso-Mora, Javier Autonomous Multi-Robots Lab Department of Cognitive Robotics School of Mechanical Engineering Delft University of Technology Delft2628 CD Netherlands State Key Laboratory of Mechanical System and Vibration School of Mechanical Engineering Shanghai Jiaotong University Shanghai200240 China

Representing the 3D environment with instance-aware semantic and geometric information is crucial for interaction-aware robots in dynamic environments. Nevertheless, creating such a representation poses challenges due to sensor noise, instance segmentation and tracking errors, and the objects’ dynamic motion. This paper introduces a novel particle-based instance-aware semantic occupancy map to tackle these challenges. Particles with an augmented instance state are used to estimate the Probability Hypothesis Density (PHD) of the objects and implicitly model the environment. Utilizing a State-augmented Sequential Monte Carlo PHD (S2MC-PHD) filter, these particles are updated to jointly estimate occupancy status, semantic, and instance IDs, mitigating noise. Additionally, a memory module is adopted to enhance the map’s responsiveness to previously observed objects. Experimental results on the Virtual KITTI 2 dataset demonstrate that the proposed approach surpasses state-of-the-art methods across multiple metrics under different noise conditions. Subsequent tests using real-world data further validate the effectiveness of the proposed approach. Copyright © 2024, The Authors. All rights reserved.

关键词： Mapping

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Building Trust in E-Commerce by Examining the Relationships Between User Experience and Delivery Satisfaction

Building Trust in E-Commerce by Examining the Relationships ...

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Digital Transformation and Applications (ICDXA), International Conference on

作者： Ivan Diryana Sudirman Iman Sudirman Iston Dwija Utama Entrepreneurship Department BINUS Business School Undergraduate Program Bina Nusantara University Bandung Indonesia Department of Mechanical Engineering Faculty of Engineering Pasundan University Bandung Indonesia

This study analyzes the relationship across user experience, delivery satisfaction, and trust within the domain of e-commerce. The variables are assessed using Partial Least Squares (PLS) to identify their interaction. This research utilised a survey approach for collecting data from a sample of 151 participants, with the intent of interpreting their points of view. The findings suggest a significant correlation across user experience and trust in the framework of online purchase. Moreover, this study demonstrates that the satisfaction of customers with the delivery process plays a role in the creation of trust, but to a lesser extent compared to the user experience. These findings provide useful insights into the approaches that online platforms could utilize to establish and maintain the trust of their users.

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Safe Control of Quadruped in Varying Dynamics via Safety Index Adaptation

arXiv

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arXiv 2024年

作者： Yun, Kai S. Chen, Rui Dunaway, Chase Dolan, John M. Liu, Changliu Mechanical Engineering Department Carnegie Mellon University PittsburghPA United States Robotics Institute Carnegie Mellon University PittsburghPA United States Mechanical Engineering Department New Mexico Institute of Mining and Technology SocorroNM United States

Varying dynamics pose a fundamental difficulty when deploying safe control laws in the real world. Safety Index Synthesis (SIS) deeply relies on the system dynamics and once the dynamics change, the previously synthesized safety index becomes invalid. In this work, we show the real-time efficacy of Safety Index Adaptation (SIA) in varying dynamics. SIA enables real-time adaptation to the changing dynamics so that the adapted safe control law can still guarantee 1) forward invariance within a safe region and 2) finite time convergence to that safe region. This work employs SIA on a package-carrying quadruped robot, where the payload weight changes in real-time. SIA updates the safety index when the dynamics change, e.g., a change in payload weight, so that the quadruped can avoid obstacles while achieving its performance objectives. Numerical study provides theoretical guarantees for SIA and a series of hardware experiments demonstrate the effectiveness of SIA in real-world deployment in avoiding obstacles under varying dynamics. © 2024, CC BY.

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Modal-Graph 3D Shape Servoing of Deformable Objects with Raw Point Clouds

arXiv

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arXiv 2023年

作者： Yang, Bohan Sui, Congying Zhong, Fangxun Liu, Yun-Hui T Stone Robotics Institute The Department of Mechanical and Automation Engineering The Chinese University of Hong Kong Hong Kong

Deformable object manipulation (DOM) with point clouds has great potential as non-rigid 3D shapes can be measured without detecting and tracking image features. However, robotic shape control of deformable objects with point clouds is challenging due to: the unknown point correspondences and the noisy partial observability of raw point clouds;the modeling difficulties of the relationship between point clouds and robot motions. To tackle these challenges, this paper introduces a novel modal-graph framework for the model-free shape servoing of deformable objects with raw point clouds. Unlike the existing works studying the object's geometry structure, we propose a modal graph to describe the low-frequency deformation structure of the DOM system, which is robust to the measurement irregularities. The modal graph enables us to directly extract low-dimensional deformation features from raw point clouds without extra processing of registrations, refinements, and occlusion removal. It also preserves the spatial structure of the DOM system to inverse the feature changes into robot motions. Moreover, as the framework is built with unknown physical and geometric object models, we design an adaptive robust controller to deform the object toward the desired shape while tackling the modeling uncertainties, noises, and disturbances online. The system is proved to be input-to-state stable (ISS) using Lyapunov-based methods. Extensive experiments are conducted to validate our method using linear, planar, tubular, and volumetric objects under different settings. Copyright © 2023, The Authors. All rights reserved.

关键词： Modal analysis

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CFD analysis of a multi-rotor flying robot for air pollution inspection 25

CFD analysis of a multi-rotor flying robot for air pollution...

引用

25th Fluid Mechanics Conference, FMC 2022

作者： Suchanek, G. Filipek, R. AGH University of Science and Technology Department of Power Systems and Environmental Protection Facilities Faculty of Mechanical Engineering and Robotics 30 Mickiewicza Av. Krakow30-059 Poland

The aim of the work was to create a CFD model of the flow generated around the drone to estimate the impact of field parameters on the results of actual measurements from PM sensors that are positioned differently in relation to the propellers. The model created with the use of the ANSYS Fluent software allowed one to determine the criterion of their sufficient distance. The robots with four, six and eight rotors were analyzed. For these, the turbulence intensity, velocity and pressure distributions were determined. The paper also presents the results of PM measurements carried out under field conditions using two sensors mounted on the hexacopter robot. © Published under licence by IOP Publishing Ltd.

关键词： Robots

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Interactive Learning of Physical Object Properties Through Robot Manipulation and Database of Object Measurements

arXiv

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arXiv 2024年

作者： Kruzliak, Andrej Hartvich, Jiri Patni, Shubhan P. Rustler, Lukas Behrens, Jan Kristof Abu-Dakka, Fares J. Mikolajczyk, Krystian Kyrki, Ville Hoffmann, Matej Department of Cybernetics Faculty of Electrical Engineering Czech Technical University in Prague Czech Republic Czech Institute of Informatics Robotics and Cybernetics Czech Technical University in Prague Czech Republic Mechanical Engineering Department Faculty of Engineering New York University Abu Dhabi United Arab Emirates Department of Electrical and Electronic Engineering Imperial College London London United Kingdom Intelligent Robotics Group Department of Electrical Engineering and Automation School of Electrical Engineering Aalto University Finland

This work presents a framework for automatically extracting physical object properties, such as material composition, mass, volume, and stiffness, through robot manipulation and a database of object measurements. The framework involves exploratory action selection to maximize learning about objects on a table. A Bayesian network models conditional dependencies between object properties, incorporating prior probability distributions and uncertainty associated with measurement actions. The algorithm selects optimal exploratory actions based on expected information gain and updates object properties through Bayesian inference. Experimental evaluation demonstrates effective action selection compared to a baseline and correct termination of the experiments if there is nothing more to be learned. The algorithm proved to behave intelligently when presented with trick objects with material properties in conflict with their appearance. The robot pipeline integrates with a logging module and an online database of objects, containing over 24,000 measurements of 63 objects with different grippers. All code and data are publicly available, facilitating automatic digitization of objects and their physical properties through exploratory manipulations. © 2024, CC BY.

关键词： Grippers

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Mechano-responsive hydrogel for direct stem cell manufacturing to therapy

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Bioactive Materials 2023年第6期24卷 387-400页

作者： Yufeng Shou Ling Liu Qimin Liu Zhicheng Le Khang Leng Lee Hua Li Xianlei Li Dion Zhanyun Koh Yuwen Wang Tong Ming Liu Zheng Yang Chwee Teck Lim Christine Cheung Andy Tay Department of Biomedical Engineering National University of Singapore117583Singapore Institute for Health Innovation&Technology National University of Singapore117599Singapore School of Civil Engineering and Architecture Wuhan University of Technology430070WuhanChina NUS Tissue Engineering Program National University of Singapore117510Singapore Lee Kong Chian School of Medicine Nanyang Technological University636921Singapore School of Mechanical and Aerospace Engineering Nanyang Technological University639798Singapore Institute of Molecular and Cell Biology Agency for ScienceTechnology and Research(A*STAR)138648Singapore Department of Orthopaedic Surgery Yong Loo Lin School of MedicineNational University of Singapore119288Singapore Mechanobiology Institute National University of Singapore117411Singapore

Bone marrow-derived mesenchymal stem cell(MSC)is one of the most actively studied cell types due to its regenerative potential and immunomodulatory *** cell expansion methods using 2D tissue culture plates and 2.5D microcarriers in bioreactors can generate large cell numbers,but they compromise stem cell potency and lack mechanical preconditioning to prepare MSC for physiological loading expected in *** overcome these challenges,in this work,we describe a 3D dynamic hydrogel using magneto-stimulation for direct MSC manufacturing to *** our technology,we found that dynamic mechanical stimulation(DMS)enhanced matrix-integrinβ1 interactions which induced MSCs spreading and *** addition,DMS could modulate MSC biofunctions including directing MSC differentiation into specific lineages and boosting paracrine activities(e.g.,growth factor secretion)through YAP nuclear localization and FAK-ERK *** our magnetic hydrogel,complex procedures from MSC manufacturing to final clinical use,can be integrated into one single platform,and we believe this‘all-in-one’technology could offer a paradigm shift to existing standards in MSC therapy.

关键词： Mesenchymal stem cell Dynamic mechanical stimulation Magnetic hydrogel Stem cell manufacturing Cell therapy

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Study on Offshore Wind Energy Potential in the Gulf of Thailand

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International Journal of Renewable Energy Research 2021年第4期11卷 1947-1958页

作者： Sawasklin, Pariyes Saeung, Somchai Taweekun, Juntakan Energy Technology Program Faculty of Engineering Prince of Songkla University Hat Yai Songkhla90112 Thailand Department of Mechanical and Mechatronics Engineering Faculty of Engineering Prince of Songkla University Hat Yai Songkhla90112 Thailand

Thailand's Alternative Energy Development Plan (AEDP) aims to reduce electric power generation from fossil fuels by generating electricity from wind. In this study, the purpsoe is to determine a good place for a wind farm installation. The wind potential of the Gulf of Thailand (GoT) was monitored every 10 minutes for four years (2017-2020) at 10 m agl of 10 meteorological masts and analyzed using the Wind Atlas Analysis and Application program (WAsP). Stations with average wind speeds greater than 3 m/s were provided to Multi Criteria Decision Analysis (MCDA) in order to find a viable offshore wind farm in GoT. Furthermore, the Annual Energy Product (AEP) was calculated and analyzed using 28 Vestas V112-3.0 MW Offshore in this study. The results revealed that Prachuap Khiri Khan and Narathiwat are two MCDA-selected stations. Prachuap Khiri Khan had a mean wind speed of 4.1 m/s and a power density of 121 W/m2, while Narathiwat had a mean wind speed of 4.5 m/s and a power density of 181 W/m2. Prachuap Khiri Khan's total net AEP was 226.7 GWh/year, with a capacity factor of 33.1%. Narathiwat's total net AEP was 270.8 GWh/year, with a capacity factor of 37%. In terms of economics, Narathiwat has a lower cost per unit than Prachuap Khiri Khan, at $0.14/kWh and $0.17 kWh, respectively. A suitable wind farm in the Gulf of Thailand allows wind energy to be used to generate electricity, which benefits the investor or people interested in offshore windfarm. © 2021. All Rights Reserved.

关键词： Fossil fuels

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FAST-LIVO2 on Resource-Constrained Platforms: LiDAR-Inertial-Visual Odometry with Efficient Memory and Computation

arXiv

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arXiv 2025年

作者： Zhou, Bingyang Zheng, Chunran Wang, Ziming Zhu, Fangcheng Cai, Yixi Zhang, Fu Laboratory Department of Mechanical Engineering University of Hong Kong Hong Kong Division of Robotics Perception and Learning KTH Royal Institute of Technology Stockholm Sweden

This paper presents a lightweight LiDAR-inertial-visual odometry system optimized for resource-constrained platforms. It integrates a degeneration-aware adaptive visual frame selector into error-state iterated Kalman filter (ESIKF) with sequential updates, improving computation efficiency significantly while maintaining a similar level of robustness. Additionally, a memory-efficient mapping structure combining a locally unified visual-LiDAR map and a long-term visual map achieves a good trade-off between performance and memory usage. Extensive experiments on x86 and ARM platforms demonstrate the system’s robustness and efficiency. On the Hilti dataset, our system achieves a 33% reduction in per-frame runtime and 47% lower memory usage compared to FAST-LIVO2, with only a 3 cm increase in RMSE. Despite this slight accuracy trade-off, our system remains competitive, outperforming state-of-the-art (SOTA) LIO methods such as FAST-LIO2 and most existing LIVO systems. These results validate the system’s capability for scalable deployment on resource-constrained edge computing platforms. Copyright © 2025, The Authors. All rights reserved.

关键词： Kalman filters

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