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Transactions of Japanese Society for Medical and Biological engineering 2023年第2-3期61卷 39-45页

作者： Sano, Hiroumi Nakadate, Hiromichi Course of Bioengineering Department of Mechanical Engineering and Robotics Faculty of Textile Science and Technology Shinshu University Japan

Repeated mild head trauma, specifically concussion, is a risk factor in contact sports such as judo, soccer, and American football. Concussion is a transient disturbance of the consciousness with no clear abnormality on computerized tomography or magnetic resonance imaging, and repeated trauma can cause psychiatric symptoms such as cognitive impairment and depression. Transcranial direct current and deep brain electrical stimulations have been reported to recover movement, consciousness, and cognitive disorders in patients with sequelae of head trauma. However, the mechanism of neuroplasticity induced by the brain stimulation has not been comprehended completely. In this study, we focused on the formation of neural circuits, which is important for the recovery of high brain functions, and we investigated the effectiveness of electrical stimulation on the mechanically injured neurites. Neurons were isolated from the cerebral cortexes of fetal rats and mechanically injured by cutting neurites using a micropipette. Neurite outgrowth was measured via microscopic observation under the following conditions: no electrical stimulation group with mechanical injury (Control), electrical stimulation group with 300 mV/mm, 20 Hz, and 15 min for 3 days before(Pre) or after(Post) mechanical injury, and electrical stimulation group for 3 days before and 3 days after mechanical injury(Pre-Post). When the neurite length after mechanical injury was less than 450 µm, the neurite lengths at day 3 were 650 ± 60 µm in Control, 851 ± 111 µm in Pre, 975 ± 135 µm in Post, and 929 ± 128 µm in Pre-Post. Conversely, when the neurite length after mechanical injury was greater than 450 µm, the neurite lengths at day 3 were 864 ± 69 µm in Control, 1419 ± 137 µm in Pre, 1236 ± 128 µm in Post and 1458 ± 145 µm in Pre-Post. These results indicate that electrical stimulation before injury promotes neurite outgrowth after injury. The stimulation effect decreased after 2 days but continued electrical st

关键词： Brain

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CHITOSAN-COLLAGEN COMPOSITE SCAFFOLDS FOR GROWTH DIRECTION GUIDANCE OF PC12 AXONS

CHITOSAN-COLLAGEN COMPOSITE SCAFFOLDS FOR GROWTH DIRECTION G...

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ASME 2024 International Design engineering Technical Conferences and Computers and Information in engineering Conference, IDETC-CIE 2024

作者： Tsai, Po-Yu Lin, Ying-Ting Wang, Gou-Jen Graduate Institute of Biomedical Engineering National Chung-Hsing University Taichung Taiwan PhD Program in Tissue Engineering and Regenerative Medicine National Chung-Hsing University Taichung Taiwan Department of Mechanical Engineering Graduate Institute of Biomedical Engineering National Chung-Hsing University Taichung Taiwan

ISBN: (纸本)9780791888421

In this study, nerve conduits of chitosan and collagen composites with biocompatibility and biodegradability were fabricated. The effects of material composition and surface morphology on the axonal growth and directionality of rat epinephric pheochromocytoma PC12 were investigated. The cells were separated by a PDMS structure to simulate nerve injury, and the growth of axons of PC12 cells was observed under the separation of large gaps. At the same time, mitochondria extracted from osteosarcoma cybrid cells (C2-GFP) were added to the culture to investigate the effect of healthy mitochondria on axon differentiation and growth. The experimental results showed that the chitosan-collagen composite film can promote the growth of PC12 axons more effectively than the pure chitosan film. Cell culture results at different groove widths also showed that smaller grooves resulted in more axon numbers and longer axon lengths. Nerve injury simulation experiments showed that the nerve repair could be almost completed after 12 days of culture. Copyright © 2024 by ASME.

关键词： Mitochondria

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Public Acceptance of Electric Vehicles in Indonesia

Public Acceptance of Electric Vehicles in Indonesia

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2022 IEEE International Conference on Industrial engineering and engineering Management, IEEM 2022

作者： Widiawati, Karsi Sopha, Bertha Maya Wardana, Fakhri Kusuma Universitas Gadjah Mada Industrial Engineering Program Department of Mechanical and Industrial Engineering Yogyakarta55281 Indonesia

ISBN: (数字)9781665486873

ISBN: (纸本)9781665486873

Electric vehicles have been considered as one of the measures to reduce emissions in Indonesia. The paper aims at understanding public acceptance toward electric vehicles in Indonesia. An empirical survey involving eighty respondents was conducted to collect data on the technical performance, the usage, the perception of electric vehicle as well as the respondents' characteristics. The data was analysis using multinomial logistic regression (MLR) to identity the significant factors explaining the acceptance toward electric vehicles. It is found that the technical performance of electric vehicles, the use of electric vehicles, perceptions of electric vehicles, and consumer characteristics are all to be significant in public acceptance of electric vehicles. Among the factors, the technical performance appears to be the most significant, whereas the usage factor (operating and maintenance cost, supporting facilities) is least significant. The application of MLR and potential interventions to improve public acceptance of electric vehicles in Indonesia are presented. Avenues for potential future research are also discussed. © 2022 IEEE.

关键词： Vehicle performance

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Development of a Smart Guidewire for Intravascular Sensing 9th

Development of a Smart Guidewire for Intravascular Sensing

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9th International Conference on the Development of Biomedical engineering in Vietnam, BME 2022

作者： Dong, Chao-Wei Joo, Dong-Hyun Moon, Ki-Jeong Yoon, Se-Yeon Nguyen, Hua Quang Huy Park, Woo-Tae Department of Mechanical Engineering Seoul National University of Science and Technology Seoul01811 Korea Republic of Convergence Program of Biomedical Engineering and Biomaterials Seoul National University of Science and Technology Seoul01811 Korea Republic of

ISBN: (纸本)9783031446290

This study presents a smart guidewire developed to measure the pressure inside blood vessels during minimally invasive surgery. The use of pressure sensor guidewires enables the medical doctor to make a judgement of the stent insertion procedure by precisely measuring coronary pressure. A pressure sensor is embedded inside the guidewire to measure the coronary lesion's vascular pressure to determine the clogging's severity. Pressure sensors inside the guidewires require high sensitivity, good linearity, and huge size reduction. The pressure sensor needs to be packaged inside a 350 µm diameter catheter. Size constraints and mechanical reliability requirements are extremely high. We describe the design and manufacture of the micro-scaled pressure sensor and the packaging process of the guidewire. To improve sensor sensitivity and reduce nonlinearity, we employed a finite element analysis to optimize the design for the membrane. The sensor fabrication process employs a cavity-first process for ultrathin sensor design. Additionally, we built a measurement system that records the sensor signal in air pressure. The results showed that the air pressure ranged up to 7.2 psi. We developed a systematic setup for assembling the ultraminiature pressure sensor inside the 800 µm guidewire. The packaging procedure includes the preparation of the electric wires, sensor placement, sensor to wire alignment, soldering, and finally, wired sensor placement inside the medical tubing. © The Author(s), under exclusive license to Springer Nature Switzerland AG. 2024.

关键词： Pressure sensors

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Resampling Strategies for Increasing Point Density in Narrow Passages for Probabilistic Roadmaps

Resampling Strategies for Increasing Point Density in Narrow...

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ASME/IFToMM International Conference on Reconfigurable Mechanisms and Robots, ReMAR

作者： Bartłomiej Bonar Tomasz Buratowski Department of Robotics and Mechatronics Faculty of Mechanical Engineering and Robotics AGH University of Krakow Kraków Poland

ISBN: (数字)9798350395969

ISBN: (纸本)9798350395976

This paper presents multiple point-sampling strategies for stochastic approach to path planning. Their main purpose is to increase points density in narrow corridors, which are often difficult areas to navigate using non-deterministic approach for path planning. At the same time, algorithms for distributing points over the area of narrow regions and reducing their number in open space are described as well as postprocessing algorithm distancing samples from obstacles. Simulation-based tests are performed to compare achieved results and estimate calculation times.

关键词： Navigation Gaussian distribution Probabilistic logic Vectors Path planning Computational efficiency Complexity theory

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Detection and Classification in Ballistic Drone Capturing Based on Transfer Learning Networks Using Infrared Images 6

Detection and Classification in Ballistic Drone Capturing Ba...

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6th IEEE Conference on Information and Communication Technology, CICT 2022

作者： Harsha Vardhan Reddy, M. Gothandaraman, Rajkumar Muthuswamy, Sreekumar Amrita School of Engineering Amrita Vishwa Vidyapeetham Department of Mechanical Engineering Chennai India Indian Institute of Information Technology Design and Manufacturing Center for Al IoT and Robotics Department of Mechanical Engineering Chennai Kancheepuram India

ISBN: (纸本)9781665473125

Unmanned aerial vehicles and drones are flying objects carrying small payloads for various applications, including agriculture, photography for weddings & religious ceremonies, e-commerce deliveries, remote sensing, 3D mapping, surveillance and defense. These flying objects also called as drones are available in two variants;1. Fixed wing propeller type, and 2. Multi-wings propeller type. Nowadays, UAVs and Drones are the primary threat to the national security on the mainland and the line of actual control. Generally, these threat-rising drones can be eradicated by anti-missile techniques, which are not economical however will destroy them. The objective of the work here is to design and develop a ballistic drone capturing system comprising two main steps;1. classification of UAVs from the flying birds and 2. Capturing the UAVs without causing significant damage to the drone. Here, the methodology uses computer-generated infrared images of the drone in the pretrained network architecture, which acts as the Convolution Neural Network (CNN) for classifying drones and birds. The performance of AlexNet and ResNet-50 performs better and it shows 100 percent efficiency and small distribution with more stability. In the near future, the ballistic capturing system will be designed and developed as a product, which would support acquiring data about malicious drones. © 2022 IEEE.

关键词： Drones

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An innovative acid-resistant elephant dung biochar powder for fermentative biohydrogen production improvement from food waste slurry

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International Journal of Hydrogen Energy 2024年 138卷 1263-1270页

作者： Pomdaeng, Prakaidao Chu, Chen-Yeon Masa-ad, Anchalee Ngamnurak, Phonsini Setthapun, Worajit Sintuya, Hathaithip Program of Mechanical and Aeronautical Engineering Feng Chia University Taiwan Institute of Green Products Feng Chia University Taiwan Chiang Mai Rajabhat University Thailand Department of Biology Technology Faculty of Technology Khon Kaen University Thailand

This research investigates the innovative application of elephant dung biochar derived from pyrolysis process as an enhancer for biohydrogen production from food waste by dark fermentation process. In this study, batch fermentation experiments have been performed with elephant dung biochar concentrations from 0 to 20 g/L. The highest yields of biogas and biohydrogen achieved were 83.33 and 12.41 mL/g COD, respectively, with the maximum hydrogen concentration reaching 21.79% at the biochar concentration of 10 g/L. Additionally, the total volatile fatty acids produced after fermentation amounted to 2204 mg/L. This study found that biochar can be used for buffering pH and enhancing metabolic processes on the pathway of VFAs to hydrogen, thereby contributing to improved hydrogen yields. This study has demonstrated that biochar produced from elephant dung can significantly improve hydrogen yield from food waste, while higher concentration of biochar may have inhibitory effects. © 2024 Hydrogen Energy Publications LLC

关键词： Biochar Dark fermentation Elephant dung Food waste Hydrogen production

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Critical Component Identification in Hovercraft assembly Through FMEA 10

Critical Component Identification in Hovercraft assembly Thr...

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10th International Conference on Emerging Trends in engineering and Technology - Signal and Information Processing, ICETET-SIP-22 2022

作者： Nakandhrakumar, R.S. Ramakrishnan, M. Dinesh Kannan, K. Anand, Gopi Sidharthan, K. Venkatasamy, Ramkumar Centre for Automation and Robotics Hindustan Institute of Technology and Science Department of Mechanical Engineering Chennai603103 India Hindustan Institute of Technology and Science Department of Mechanical Engineering Chennai603103 India

ISBN: (纸本)9781665467414

The goal of this study is to use the proactive procedure to categorize the failure, which likely to occur in hovercraft assembly. First, the hovercraft model is developed for standard sizes to identify the critical component through FMEA concept. This involves predicting critical component through SOD analysis and defining by RPN for all failure modes in the regular monitoring and replacement of parts. The conventional FMEA provides prioritization to the mating components by giving higher values for severity, occurrence and detection indexes. Many a time experts may disagree in the ranking index due to condition status of the component. In this project work, the attempt made to give range of values through which higher values to be given with more focus and lower values can be allowed to run further and further moderate values to be used for regular monitoring. This approach offers an effective way for such complicated assembly with much limited or unreliable data. © 2022 IEEE.

关键词： Information processing Market research Indexes Monitoring Standards

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Robotic arm controlled Acoustofluidic End-Effector for particle manipulation 26

Robotic arm controlled Acoustofluidic End-Effector for parti...

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26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022

作者： Durrer, Jan Agrawal, Prajwal Ahmed, Daniel Acoustic Robotics Systems Laboratory Institute for Mechanical Systems Department of Mechanical and Process Engineering ETH Zurich Rushlikon8803 Switzerland

ISBN: (纸本)9781733419048

With the development of microfluidics, fluid manipulation is becoming an increasingly critical process. In the macroscale environment, numerous robotic systems are commercially available, however development of these systems at the microscale requires expensive equipment's and reagents, as well as sample preparation at the microscale is relatively difficult. This work integrates robotics and microfluidics in order to demonstrate a robot-assisted acoustofluidic microscale manipulation system (RAMS), incorporating an acoustofluidic end effector and a robotic arm. This RAMS device will open the door to new potential applications such as micromixing, pumping, particle manipulation, and transfection, for example. © 2022 MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.

关键词： End effectors

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Synthesis and Characterization of Silver -doped Hydroxyapatite-Coated Polyether ether ketone for Dental Applications 15

Synthesis and Characterization of Silver -doped Hydroxyapati...

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15th Biomedical engineering International Conference, BMEiCON 2023

作者： Wailerdsak, Tanawat Ngamkham, Kamolchanok Khantachawana, Anak King Mongkut's University of Technology Thonburi Department of Biological Engineering Program Bangkok Thailand King Mongkut's University of Technology Thonburi Department of Mechanical Engineering Bangkok Thailand

ISBN: (纸本)9798350345247

The main objective of this paper is to develop and characterize silver-doped hydroxyapatite (Ag-HA) coating on Polyether ether ketone (PEEK). The physicochemical characteristic of Ag-HA coated on PEEK was evaluated by X-ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FTIR), and also determining calcium (Ca) / phosphorus (P) ratio and silver (Ag) / calcium (Ca) ratio by inductive coupled plasma atomic emission spectroscopy (ICP-AES). The surface morphology of Ag-HA coated on PEEK was analyzed by scanning electron microscopy (SEM). XRD, FTIR, and ICP-AES analysis of the coated layer confirms Ag-HA deposition on PEEK, the Ag successfully substitutes Ca in the hydroxyapatite (HA) lattice. The Ag substitution is not 100 % as compared with the initial added Ag. Surface morphology analysis of Ag-HA-coated PEEK reveals the flake structure of Ag-HA formation on PEEK. © 2023 IEEE.

关键词： Hydroxyapatite

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