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Facile synthesis of cobalt, nickel and manganese-based metal organic framework derived layered double hydroxides on Ni foam as effective binder-free electrodes of energy storage devices

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Journal of Energy Storage 2024年 78卷

作者： Kuo, Tsung-Rong Huang, Jing-Mei You, Xiang-Yu Subbiramaniyan, Kubendhiran Kongvarhodom, Chutima Saukani, Muhammad Yougbaré, Sibidou Chen, Hung-Ming Lin, Lu-Yin International PhD Program in Biomedical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Graduate Institute of Nanomedicine and Medical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Department of Chemical Engineering and Biotechnology National Taipei University of Technology Taipei Taiwan Department of Chemical Engineering King Mongkut's University of Technology Thonburi 126 Pracha-u-thit Toong-kru Bangkok10140 Thailand Department of Mechanical Engineering Faculty of Engineering Universitas Islam Kalimantan MAB Jl. Adhyaksa No. 2 Banjarmasin70124 Indonesia /Nanoro 03 B.P 7192 Ouagadougou03 Burkina Faso Gingen technology Co. LTD. Rm. 7 10F. No.189 Sec. 2 Keelung Rd. Xinyi Dist. Taipei11054 Taiwan

Metal organic framework (MOF) derivatives have attracted intensive attention as the active material of energy storage devices. Layered double hydroxide (LDH) with large surface area, high redox capability and good cycling stability is regard as one of efficient active materials. Developing MOF-derived LDH with multiple metals can possibly achieve excellent surface properties, high electrical conductivity and abundant redox reactions. However, synthesizing MOF-derived LDH is time-consuming and requires high temperature environments. In this work, a simple and time-effective precipitation and etching process is proposed to synthesize MOF-derived LDH on nickel foam (NF) as binder-free electrodes of energy storage devices. The cobalt, nickel and manganese are utilized to design MOF-derived LDH with different metal species and numbers. The trimetallic MOF-derived LDH based on Co, Ni and Mn presents a high specific capacitance (CF) of 1113.7 F/g at 20 mV/s, due to abundant electroactive sites and multiple redox states for carrying out large numbers of redox reactions. The energy storage device composed of the trimetallic MOF-derived LDH and carbon on NF as electrodes presents the maximum energy density of 61.5 Wh/kg at the power density of 750 W/kg, and the CF retention of 92.5% and Coulombic efficiency of 95% after 10,000 charge/discharge cycles. © 2023 Elsevier Ltd

关键词： Electrodes

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CuO NWs boosted triboelectric microfluidic nanosensor functionalized by collagen-protein interactions for real-time platelet count monitoring

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Chemical engineering Journal 2024年 490卷

作者： Lin, Jia-Cheng Kaswan, Kuldeep Chatterjee, Subhodeep Wu, Yu-Wen Kumar Sharma, Manish Ranjan, Ashok Roy Barman, Snigdha Lin, Yu-Zih Burnouf, Thierry Boireau, Wilfrid Lu, Ming-Yen Tu, Yong-Kwang Su, I-Chang Wu, Ping-Hsiu Lin, Zong-Hong Fan, Yu-Jui School of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Taipei Neuroscience Institute Taipei Medical University Taipei11031 Taiwan Department of Biomedical Engineering National Taiwan University Taipei11031 Taiwan International Intercollegiate PhD Program National Tsing Hua University Hsinchu30013 Taiwan Department of Power Mechanical Engineering National Tsing Hua University Hsinchu30013 Taiwan Graduate Institute of Biomedical Materials and Tissue Engineering Taipei Medical University Taipei11031 Taiwan Department of Material Science and Engineering National Tsing Hua University Hsinchu30013 Taiwan Institute of Biomedical Engineering National Tsing Hua University Hsinchu30013 Taiwan International PhD Program in Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Université de Franche-Comté CNRS Institut FEMTO-ST BesançonF-25030 France Department of Neurosurgery Shuang Ho Hospital Taipei Medical University New Taipei City23561 Taiwan Department of Surgery School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Department of Radiology School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Department of Radiation Oncology Taipei Medical University Hospital Taipei11031 Taiwan Center for Precision Health and Quantitative Sciences Taipei Medical University Hospital Taipei 11031 Taiwan

Blood platelet count significantly affects the development of severe conditions like myocardial infarction, peripheral arterial ischemia, respiratory compromise, stroke, diabetes, coronavirus disease 2019 (COVID-19), along with chemotherapy patients and those suffering cardiovascular diseases (CVDs). These conditions necessitate frequent monitoring of platelet counts to guide diagnostic and therapeutic decisions. However, existing techniques are relatively time-consuming, lack of accuracy and require precise operation. The emergence of these severe diseases underscored the need to develop advanced platelet count-monitoring techniques which are rapid, highly precise, and conveniently portable for point-of-care applications. In this study, we emphasized the development of a triboelectric microfluidic nanosensor (TMNS) for platelet quantification through the assessment of flow resistance. The functionality of TMNS device is based on immobilization of platelets on a collagen layer coated inside a microfluidic channel. The triboelectric voltage output is measured as a detection signal of the flow resistance and is enhanced by incorporating high surface area copper oxide nanowires (CuO NWs) on the interior of copper tubes. These copper tubes serve as terminal electrodes and for flow guiding. The flow resistance of plasma solutions is elevated when the platelet concentration increases due to heightened adherence of platelets onto the collagen layer. Variations in flow resistance induce alterations in contact electrification, causing changes in output voltage at load terminals. Fine-tuning of the TMNS device was achieved by optimizing the channel width and length, flowing liquid viscosity, and voltage measurement technique. Platelet quantification sensing data were acquired through the combination of platelet-rich plasma (PRP) and platelet-poor plasma (PPP) solutions. The described device exhibits promising capabilities for platelet-count monitoring in whole-blood samples c

关键词： Copper oxides

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A triboelectric nanogenerator-based tactile sensor array system for monitoring pressure distribution inside prosthetic limb

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Nano Energy 2023年 111卷

作者： Chang, Kuie-Bin Parashar, Parag Shen, Li-Chien Chen, An-Rong Huang, Yan-Tsz Pal, Arnab Lim, Kee-Chin Wei, Po-Han Kao, Fu-Cheng Hu, Jin-Jia Lin, Zong-Hong Department of Mechanical Engineering National Yang Ming Chiao Tung University Hsinchu Taiwan Department of Biomedical Engineering National Taiwan University Taipei Taiwan Department of Material Science and Engineering National Tsing Hua University Hsinchu Taiwan Institute of Biomedical Engineering National Tsing Hua University Hsinchu Taiwan International Intercollegiate PhD Program National Tsing Hua University Hsinchu Taiwan Department of Orthopaedic Surgery Chang Gung Memorial Hospital Taoyuan Taiwan College of Medicine Chang Gung University Taoyuan Taiwan Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu30013 Taiwan

In the prosthetic field, quantifying interfacial pressure distribution between the amputee's residual limb and the socket's internal environment is imperative for developing new technologies. However, the commercially available pressure sensors have several disadvantages, namely external power supply requirements, low stability, high cost, and complexities related to integrating the sensor system into prosthetic devices. Herein, we propose a self-powered triboelectric nanogenerator (TENG) based flexible tactile sensor array system to monitor prosthetic socket internal pressure distribution in real-time. The proposed sensor consists of biocompatible polydimethylsiloxane (PDMS) polymer and polycaprolactone (PCL) nanofiber membranes as triboelectric materials. The biodegradable PCL nanofiber membrane, fabricated via a scalable and cost-effective electrospinning process, possesses a high surface area-to-volume ratio, facilitating enhanced charge generation during triboelectrification. The as-fabricated TENG-based tactile sensor is highly stable up to 10,000 cycles. Furthermore, the voltage of the tactile sensor is independent of different temperature and humidity values, demonstrating the stability of the sensor under various environmental conditions. Finally, we successfully integrated the tactile sensor array within a prosthetic device to monitor real-time pressure distribution inside the prosthetic socket during gait simulation. We believe that the proposed novel design provides a new dimension for the rapid development of self-powered, low-cost, and highly stable pressure monitoring systems with considerable potential for commercialization. © 2023 Elsevier Ltd

关键词： Electrospinning

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Emergence of Non-photoresponsive Catalytic Techniques for Environmental Remediation and Energy Generation

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Chemistry - An Asian Journal 2023年第9期18卷 e202300090页

作者： Kumar Sharma, Manish Khan, Imran Kaswan, Kuldeep Roy Barman, Snigdha Saha, Subhajit Hsieh, Wu-Chiao Chueh, Yu-Lun Wang, Yu-Lin Lee, Sangmin Choi, Dukhyun Lin, Zong-Hong Department of Materials Science and Engineering National Tsing Hua University Hsinchu30013 Taiwan Institute of NanoEngineering and Microsystems National Tsing Hua University Hsinchu30013 Taiwan International Intercollegiate PhD Program National Tsing Hua University Hsinchu30013 Taiwan Department of Renewable Energy Maulana Abul Kalam Azad University of Technology West Bengal741249 India Department of Obstetrics and Gynecology Chang Gung Memorial Hospital and College of Medicine Chang Gung University Taoyuan333 Taiwan Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu30013 Taiwan School of Mechanical Engineering Chung-Ang University Seoul06974 Korea Republic of Department of Mechanical Engineering Sungkyunkwan University Suwon16419 Korea Republic of Department of Biomedical Engineering National Taiwan University Taipei10617 Taiwan

Catalysis plays a crucial role in all the major applications and challenges in the environment, including energy generation and environmental remediation. Although photocatalysts and electrocatalysts are useful in addressing energy and environmental issues, they have some major drawbacks, such as low efficiency and easy charge recombination which limits their applications. Hence, it is imperative to design and explore new catalytic techniques that include non-photoresponsive catalysts. In this review, the detailed possibilities, characteristics and prospects of non-photoresponsive catalysts, such as piezocatalysts, thermocatalysts, pyrocatalysts, and tribocatalysts along with hybrid catalysts are described. The overall mechanism of each catalytic technique and its applications in different fields such as energy generation, environmental remediation, and carbon dioxide reduction are discussed. © 2023 Wiley-VCH GmbH.

关键词： Electrocatalysts

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Arsenal ship program certification plan

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NAVAL ENGINEERS JOURNAL 1998年第1期110卷 249-261页

作者： Arntson, S Lind, W Turner, JJ Blaiklock, WC Tedesco, M Stephen G. Arntson is an independent consultant. A degree Naval Architect he has over 38 years of experience in the design construction and maintenance of surface ships. His experience includes 28 yeus with the Naval Sea Systems Command Naval Ship Engineering Centerl Bureau of Ships specializing in the structural design of Naval surface ships and 7 years with ABS Specializing in the application of commercial ship design practices. Most recently he worked with both NASSCO and ABS MZ the Arsenal Ship Program. Steve was very active with the Ships Structure Committee in developing R&D programs for ship structure and he is a member of the ASNE Journal Committee. Steve received a BS in Mechanical Engineering (Naval Architecture Option) from Virginia Polytechnic Institute in 1964. He is a member of the ASNE TAU BETA PI PI TAU SIGMA and PHI KAPPA PHI. William 1. Lind joined ABS in 1992 after ten years with Sparkman and Stephens Inc. He is currently ABS Amekas Manager of Engineering jm New Orleans and Cleveland. Both ofices conduct plan reviews for militavy commercial and private marine craft fm self-propelled vessels under 300 feet in length and bargus unlimited in length. As Vice-Chaimn ojthe Western Rivers Technical Committee Great Lakes Technical Committee and the Small Vessel Committee Bill participated in the writing of the 1997 ABS Guide for Building and Classing High Speed Craft and the 1997 ABS Rules for Building and Classing Steel Vessels Under 9OM. Bill received an MBA from Florida Atlantic University in 1995 a BS in Mechanical Engineering from New York Institute of Technology in 1986 and a BA in Histoy from Colgate University in 1976. He is Chaimn of SNAME HS-9 Composite Panel Testing & Fire Protection and a member of ASNE. John J. Turner is Senior Vice President of SYNTEK Technologies Inc. in Arlington Virginia. SYNTEK specializes in activities of a highly technical nature supporting both industry and government in domestic and international markets. He is a registered Professional Engineer

The Defense Advanced Research Project Agency (DARPA), in conjunction with the U.S. Navy, initiated a research program for the design and construction of a distinctive warship for the 21st century known as the Arsenal Ship. By using an innovative development and acquisition approach it was hoped to streamline the procurement process and reduce costs. In an environment where budgets are being cut, both industry and Government were challenged to develop, design, and produce the innovative ship and related mission systems to meet specific performance capabilities within strict affordability constraints. A key element of this innovative acquisition approach was a new certification scheme designed to replace the traditional test and evaluation (T&E) and acceptance process. The purpose of this paper is to describe the development of the certification plan during Phase LI of the Arsenal Ship program by the American Bureau of Shipping and the contending Shipyard teams, and to discuss the potential benefits of this alternative certification approach. Although the Arsenal Ship program was canceled late in 1997, insight derived from the exploration of new certification concepts could benefit future design and building programs.

关键词： Warships

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Corrigendum to “Elevated temperature nanoindentation characterization of poly( para -phenylene vinylene) conjugated polymer films” [Polym. Test. 41 (2015) 17–25]

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Polymer Testing 2015年 42卷 234-234页

作者： Nimitt G. Patel Arvind Sreeram Ramaswamy I. Venkatanarayanan Sitaraman Krishnan Philip A. Yuya Department of Mechanical and Aeronautical Engineering Clarkson University Potsdam NY 13699 USA Materials Science and Engineering PhD Program Clarkson University Potsdam NY 13699 USA Department of Chemical and Biomolecular Engineering Clarkson University Potsdam NY 13699 USA

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Deconvoluting clonal and cellular architecture in IDH -mutant acute myeloid leukemia

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Cell Stem Cell 2025年

作者： Maria Sirenko Soobeom Lee Zhengxi Sun Ronan Chaligne Sanam Loghavi Georgios Asimomitis Charlotte K. Brierley Elsa Bernard Sheng F. Cai Robert M. Myers Bettina Nadorp Junya Sango Morgan Lallo Max F. Levine Dylan Domenico Juan E. Arango Ossa Juan S. Medina-Martinez Kamal Menghrajani Audrey Lasry Alice S. Mims Elli Papaemmanuil Department of Pathology New York University Grossman School of Medicine New York NY USA Laura and Isaac Perlmutter Cancer Center New York University Grossman School of Medicine New York NY USA Louis V. Gerstner Jr. Graduate School of Biomedical Sciences Memorial Sloan Kettering Cancer Center New York NY USA Computational Oncology Service Department of Epidemiology and Biostatistics Memorial Sloan Kettering Cancer Center New York NY USA Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston TX USA Department of Biology New York University New York NY USA Program for Computational and Systems Biology Sloan Kettering Institute Memorial Sloan Kettering Cancer Center New York NY 10065 USA Biomedical Systems Laboratory Department of Mechanical Engineering National Technical University of Athens Athens Greece Medical Research Council Weatherall Institute of Molecular Medicine University of Oxford Oxford UK NIHR Biomedical Research Centre University of Oxford Oxford UK Leukemia Service Department of Medicine Center for Hematologic Malignancies Memorial Sloan Kettering Cancer Center New York NY USA Human Oncology and Pathogenesis Program Memorial Sloan Kettering Cancer Center New York NY USA Tri-Institutional MD-PhD Program Weill Cornell Medicine Rockefeller University Memorial Sloan Kettering Cancer Center New York NY USA Division of Precision Medicine Department of Medicine New York University School of Medicine New York NY USA Department of Oncological Sciences Tisch Cancer Institute Center for Advancement of Blood Cancer Therapies Icahn School of Medicine at Mount Sinai New York NY USA Vilcek Institute of Graduate Biomedical Sciences NYU Grossman School of Medicine New York NY USA Clara D. Bloomfield Center for Leukemia Outcomes Research The Ohio State University Comprehensive Cancer Center Columbus OH USA Division of Hematology Department of Internal Medicine The Ohio State University Comprehensive Cancer Cen

Isocitrate dehydrogenase 1/2 ( IDH ) mutations are early initiating events in acute myeloid leukemia (AML). The complex clonal architecture and cellular heterogeneity in IDH- mutant AML underlies the heterogeneous clinical presentation and outcomes. Integrating single-cell genotyping and transcriptomics, we demonstrate a stem-like and inflammatory phenotype of IDH -mutant AML and identify clone-specific programs associated with NPM1 , NRAS , and SRSF2 co-mutations. Furthermore, these clones had distinct responses to treatment with combination IDH inhibitors and chemotherapy, including elimination, reconstitution of myeloid differentiation, or retention within progenitor populations. At relapse after IDH inhibitor monotherapy, we identify upregulated stemness, inflammation, mitochondrial metabolism, and anti-apoptotic factors, as well as downregulated major histocompatibility complex (MHC) class II antigen presentation. At the pre-leukemic stage, we observe upregulation of IDH2 -associated pathways, including inflammation. We deliver a detailed phenotyping of IDH -mutant AML and a framework for dissecting contributions of recurrently mutated genes in AML at diagnosis and following therapy, with implications for precision medicine.

关键词： IDH inhibitors IDH1/2 mutations acute myeloid leukemia cellular hierarchy clonal architecture clonal evolution relapse single-cell transcriptomics targeted therapy treatment resistance

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Super Resolution for Improved Positioning of an MRI-Guided Spinal Cellular Injection Robot

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Journal of Medical Robotics Research 2021年第1-2期6卷

作者： Martinez, Daniel Enrique Meinhold, Waiman Oshinski, John Hu, Ai-Ping Ueda, Jun Robotics PhD Program Georgia Institute of Technology North Ave NW Atlanta 30332 GA United States Department of Radiology Emory University 201 Dowman Dr Atlanta 30322 GA United States Intelligent Sustainable Technologies Division Georgia Tech Research Institute 640 Strong Street Atlanta 30318 GA United States George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology North Ave NW Atlanta 30332 GA United States

This paper presents the development of a magnetic resonance imaging (MRI)-conditional needle positioning robot designed for spinal cellular injection. High-accuracy targeting performance is achieved by the combination of a high precision, parallel-plane, needle-orientation mechanism utilizing linear piezoelectric actuators with an iterative super-resolution (SR) visual navigation algorithm using multi-planar MR imaging. In previous work, the authors have developed an MRI conditional robot with positioning performance exceeding the standard resolution of MRI, rendering the MRI resolution the limit for navigation. This paper further explores the application of SR to images for robot guidance, evaluating positioning performance through simulations and experimentally in benchtop and MRI experiments. © 2021 World Scientific Publishing Company.

关键词： cellular therapeutics magnetic resonance imaging needle steering spinal cord Super resolution surgical robots visual robot guidance

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Coordinated control and its implementation

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Process Safety Progress 1982年第2期1卷 85-90页

作者： C. S. Lin T. H. Tsai J. W. Lane Tenneco Inc. Houston Texas 77001 Cheng S. Lin:was born in Taiwan and received a BS in Mechanical Engineering at Cheng Kung University. He came to the Rensselaer Polytechnic Institute in 1959 where he received a MME in Mechanical Engineering in 1962 and a PhD in Mechanical Engineering in 1966 He spent three years at West Virginia Pulp and Paper Co. in Process Control Research three years at TRW Inc. Systems Group on the Apollo program and nine years at Bonner and Moore Assoc. installing process control systems worldwide. He joined the Operations Technologies Department of Tenneco Inc. as a Consulting Engineer in June 1980. He is a US citizen and a member of IEEE. Thomas H. Tsai:is a Managing Engineer of the Operations Technologies Department of Tenneco Inc. He is a Registered Professional Engineer in the State of Calif. and is a Member of AIChE and a Senior Member of ISA. He received a BS degree in Chemical Engineering at Tunghan University of Taiwan and attended graduate school at Oklahoma State University. James W. Lane:received a BE and MS in Chemical Engineering from the University of Southern California. He is a Registered Professional Engineer in the States of Tex and Calif. and is a Member of the AIChE Senior Member of the IEEE and Senior Member of the SME. For the last seven years he has been Director of the Operations Technologies Department of Tenneco Inc. a cooperate engineering group providing expertise in advanced control technology for process control energy management and environmental monitoring systems.

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Microfluidic nanodevices for drug sensing and screening applications

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Biosensors and Bioelectronics 2023年 219卷 114783页

作者： Pal, Arnab Kaswan, Kuldeep Barman, Snigdha Roy Lin, Yu-Zih Chung, Jun-Hsuan Sharma, Manish Kumar Liu, Kuei-Lin Chen, Bo-Huan Wu, Chih-Cheng Lee, Sangmin Choi, Dongwhi Lin, Zong-Hong Institute of Biomedical Engineering National Tsing Hua University Hsinchu30013 Taiwan International Intercollegiate PhD Program National Tsing Hua University Hsinchu30013 Taiwan Department of Power Mechanical Engineering National Tsing Hua University Hsinchu30013 Taiwan Department of Materials Science and Engineering National Tsing Hua University Hsinchu30013 Taiwan Department of Chemistry National Tsing Hua University Hsinchu30013 Taiwan Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu30013 Taiwan Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital Linkou Medical Center Taoyuan333 Taiwan Center of Quality Management National Taiwan University Hospital Hsinchu Branch Hsinchu30059 Taiwan College of Medicine National Taiwan University Taipei10051 Taiwan Institute of Cellular and System Medicine National Health Research Institute Zhunan 35053 Taiwan School of Mechanical Engineering Chung-Ang University Seoul06974 Korea Republic of Kyung Hee University Gyeonggi 17104 Korea Republic of

The outbreak of pandemics (e.g., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 in 2019), influenza A viruses (H1N1 in 2009), etc.), and worldwide spike in the aging population have created unprecedented urgency for developing new drugs to improve disease treatment. As a result, extensive efforts have been made to design novel techniques for efficient drug monitoring and screening, which form the backbone of drug development. Compared to traditional techniques, microfluidics-based platforms have emerged as promising alternatives for high-throughput drug screening due to their inherent miniaturization characteristics, low sample consumption, integration, and compatibility with diverse analytical strategies. Moreover, the microfluidic-based models utilizing human cells to produce in-vitro biomimetics of the human body pave new ways to predict more accurate drug effects in humans. This review provides a comprehensive summary of different microfluidics-based drug sensing and screening strategies and briefly discusses their advantages. Most importantly, an in-depth outlook of the commonly used detection techniques integrated with microfluidic chips for highly sensitive drug screening is provided. Then, the influence of critical parameters such as sensing materials and microfluidic platform geometries on screening performance is summarized. This review also outlines the recent applications of microfluidic approaches for screening therapeutic and illicit drugs. Moreover, the current challenges and the future perspective of this research field is elaborately highlighted, which we believe will contribute immensely towards significant achievements in all aspects of drug development. © 2022 Elsevier B.V.

关键词： Microfluidics

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