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Correction to: Air change rate effects on the airborne diseases spreading in Underground Metro wagons

Environmental science and pollution research international 2021年第24期28卷 31908页

作者： Mostafa El-Salamony Ahmed Moharam Amr Guaily Mohammed A Boraey Aerospace Department College of Engineering Peking University Beijing 100871 China. elsalamony.mostafa@***. Smart Engineering Systems Research Center (SESC) Nile University Sheikh Zayed City 12588 Egypt. Department of Engineering Mathematics and Physics Faculty of Engineering Cairo University Giza 12613 Egypt. Mechanical Engineering Program School of Engineering and Applied Sciences Nile University Sheikh Zayed City 12588 Egypt. Mechanical Power Engineering Department Zagazig University Zagazig 44519 Egypt.

A Correction to this paper has been published: https://***/10.1007/s11356-021-13405-8

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Immunometabolic Pathways: Investigating Mediators of Major Depressive Disorder and Atherosclerotic Cardiovascular Disease Comorbidity

Biological Psychiatry Global Open Science

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Biological Psychiatry Global Open Science 2025年第5期5卷

作者： Angela Koloi Nabila P.R. Siregar Rick Quax Antonis I. Sakellarios Femke Lamers Arja Rydin Kevin Dobretz Costas Papaloukas Dimitrios I. Fotiadis Jos A. Bosch Unit of Medical Technology and Intelligent Information Systems Department of Materials Science and Engineering University of Ioannina Ioannina Greece Department of Biological Applications and Technology University of Ioannina Ioannina Greece Department of Clinical Psychology University of Amsterdam Amsterdam the Netherlands Department of Medical Psychology Amsterdam University Medical Center Amsterdam the Netherlands Computational Science Laboratory Institute of Informatics University of Amsterdam Amsterdam the Netherlands Biomedical Engineering of the Department of Mechanical Engineering and Aeronautics University of Patras Patras Greece Department of Psychiatry Amsterdam University Medical Center VU Amsterdam Amsterdam the Netherlands Amsterdam Public Health Mental Health Program Amsterdam the Netherlands Cardiology Geneva University Hospitals Geneva Switzerland Department of Medicine University of Geneva Geneva Switzerland Biomedical Research Institute Foundation for Research and Technology - Hellas Ioannina Greece

Background Major depressive disorder (MDD) and cardiovascular diseases (CVDs) often co-occur whereby comorbidity results in poorer clinical outcomes, presumably due to shared immunometabolic pathways. Identifying shared biomarkers for MDD-CVD comorbidity may provide targets for prevention or treatment. Methods Using data from the NESDA (Netherlands Study of Depression and Anxiety) ( n = 2256, 66.3% female, mean age 41.86 ± 13.08 years at baseline), validated with the UK Biobank (UKB) data ( n = 35,668, 56.14% female, mean age 63.95 ± 7.74 years), this study aimed to identify 1) biomarkers, closely associated with current MDD, and 2) longitudinal pathways linking MDD and atherosclerotic CVD. Plasma metabolites (nuclear magnetic resonance) and inflammatory markers were used as exposures within a machine learning framework. Influential biomarkers were integrated into a temporal network analysis linking MDD to subsequent CVDs, exploring longitudinal pathways through causal discovery, validated by sensitivity analysis and centrality assessment. External validation included mediation and regression analysis adjusting for covariates. Results Network analysis identified stable direct paths from MDD to CVDs via tumor necrosis factor α (TNF-α), tyrosine, and fatty acids and indirect paths via acetate, high-density lipoprotein (HDL) diameter, interleukin 6, AGP, high-sensitivity C-reactive protein, and low-density lipoprotein triglycerides. Among these, acetate, tyrosine, AGP (α 1 -acid glycoprotein), and HDL diameter potentially mediated the MDD-CVD connection, given that these were identified as key nodes within the network. UKB validation confirmed HDL diameter (β = 0.004) and AGP (β = 0.003) as significant depression-CVD mediators (both p < .001), after adjusting for age, sex, deprivation index, alcohol consumption, smoking status, physical activity, and body mass index. Conclusions These analyses identified biomarkers shared in MDD and CVDs and may drive comorbid patholog

关键词： Biomarkers CVD Machine learning MDD Mediators

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Assessing industry 4.0 technology deployment projects

Assessing industry 4.0 technology deployment projects

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2018 Institute of Industrial and systems Engineers Annual Conference and Expo, IISE 2018

作者： Beller, Cassiano Souza Muncinelli, Gianfranco De Lima, Edson Pinheiro Deschamps, Fernando Industrial and Systems Engineering Graduate Program Pontifical Catholic University of Parana Curitiba Brazil Federal University of Technology - Parana Curitiba Brazil Department of Mechanical Engineering Federal University of Parana Curitiba Brazil

Industry 4.0 has recently become an ubiquitous topic of study both by academics and practitioners. Beyond the technology application domain, one major issue that most organizations have to face when structuring their efforts towards Industry 4.0 is the identification of viable opportunities for the deployment of Industry 4.0-related technologies. Proof of concept projects are usually developed to address this, as they are an exploratory means to quickly assess the application of a given technology to a specific context. If results are positive, these projects may grow into larger projects that will be used to deploy the considered technologies in a wider scale. This work aims to propose a framework that helps facilitate the assessment of proof of concept projects and their transition into wider scale projects. This framework is based both in the existing literature on Industry 4.0 technologies and in case studies of proof of concept projects that were used to assess such technologies. The framework is composed of three main components: the technologies being evaluated, the design objectives that they meet and the outcomes that are expected. The relationships among these components is also considered, and a process that mediates their use is proposed. © 2018 Institute of Industrial Engineers (IIE). All rights reserved.

关键词： Project management

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Control of brain network dynamics across diverse scales of space and time

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Physical Review E 2020年第6期101卷 062301-062301页

作者： Evelyn Tang Harang Ju Graham L. Baum David R. Roalf Theodore D. Satterthwaite Fabio Pasqualetti Danielle S. Bassett Department of Bioengineering School of Engineering & Applied Science University of Pennsylvania Pennsylvania 19104 USA Max Planck Institute for Dynamics and Self-Organization Göttingen 37079 Germany Neuroscience Graduate Program Perelman School of Medicine University of Pennsylvania Pennsylvania 19104 USA Department of Psychiatry Perelman School of Medicine University of Pennsylvania Pennsylvania 19104 USA Department of Mechanical Engineering University of California Riverside Riverside California 92521 USA Department of Physics & Astronomy College of Arts & Sciences University of Pennsylvania Pennsylvania 19104 USA Department of Electrical & Systems Engineering School of Engineering & Applied Science University of Pennsylvania Pennsylvania 19104 USA Department of Neurology Perelman School of Medicine University of Pennsylvania Pennsylvania 19104 USA Santa Fe Institute Santa Fe New Mexico 87501 USA

The human brain is composed of distinct regions that are each associated with particular functions and distinct propensities for the control of neural dynamics. However, the relation between these functions and control profiles is poorly understood, as is the variation in this relation across diverse scales of space and time. Here we probe the relation between control and dynamics in brain networks constructed from diffusion tensor imaging data in a large community sample of young adults. Specifically, we probe the control properties of each brain region and investigate their relationship with dynamics across various spatial scales using the Laplacian eigenspectrum. In addition, through analysis of regional modal controllability and partitioning of modes, we determine whether the associated dynamics are fast or slow, as well as whether they are alternating or monotone. We find that brain regions that facilitate the control of energetically easy transitions are associated with activity on short length scales and slow timescales. Conversely, brain regions that facilitate control of difficult transitions are associated with activity on long length scales and fast timescales. Built on linear dynamical models, our results offer parsimonious explanations for the activity propagation and network control profiles supported by regions of differing neuroanatomical structure.

关键词： Network diffusion Synchronization Brain network Magnetic resonance imaging

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Understanding Inchworm Crawling for Soft-Robotics

arXiv

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arXiv 2019年

作者： Gamus, Benny Salem, Lior Gat, Amir D. Or, Yizhar Faculty of Mechanical Engineering Technion – Israel Institute of Technology Technion City Haifa3200003 Israel Technion Autonomous Systems Program Technion - Israel Institute of Technology Technion City Haifa3200003 Israel

Crawling is a common locomotion mechanism in soft robots and nonskeletal animals. In this work we propose modeling soft-robotic legged locomotion by approximating it with an equivalent articulated robot with elastic joints. For concreteness we study the inchworm crawling of our soft robot with two bending actuators, via an articulated three-link model. The solution of statically indeterminate systems with stick-slip contact transitions requires for a novel hybrid-quasistatic analysis. Then, we utilize our analysis to investigate the influence of phase-shifted harmonic inputs on performance of crawling gaits, including sensitivity analysis to friction uncertainties and energetic cost of transport. We achieve optimal values of gait parameters. Finally, we fabricate and test a fluid-driven soft robot. The experiments display good agreement with the theoretical analysis, proving that our simple model correctly captures and explains the fundamental principles of inchworm crawling and can be applied to other soft-robotic legged robots. Copyright © 2019, The Authors. All rights reserved.

关键词： Stick-slip

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Aligning organizational and operations performance: A process-based approach

Aligning organizational and operations performance: A proces...

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2018 Institute of Industrial and systems Engineers Annual Conference and Expo, IISE 2018

作者： Gorte, Leticia Deschamps, Fernando De Lima, Edson Pinheiro Keathley-Herring, Heather Industrial and Systems Engineering Graduate Program Pontifical Catholic University of Parana Curitiba Brazil Department of Mechanical Engineering Federal University of Parana Curitiba Brazil Federal University of Technology - Parana Curitiba Brazil Department of Industrial Engineering and Management Systems University of Central Florida Orlando United States

Organizational models of production systems that focus on services and servitization are experiencing an increase in an application. These models emphasize the value proposition for the customer and a better understanding of the value creation process. Additionally, the emergence of new technologies such as those associated with Industry 4.0 also requires well-structured and results-oriented processes. In this perspective, although there are several tools for measuring both operations and organizational performance, the literature still lacks tools that integrate and align these two perspectives, accounting for activities at the operational level that reflect objectives at the strategic level, and vice-versa. Therefore, a procedure for aligning process performance (operations' performance) and strategic performance (organizational performance) in a service context is proposed. This procedure is based on three main components identified through a literature review: (1) guidelines associated with enterprise engineering that focus on processes, developed by Deschamps (2013);(2) a set of critical success factors for implementation of performance measurement systems that focus on organizational performance, developed by Keathley (2016);and (3) ten determinants of service quality, proposed by Parasuraman (1985). The alignment procedure is presented as being mediated by Parasuraman's model, relating enterprise engineering guidelines and critical success factors. © 2018 Institute of Industrial Engineers (IIE). All rights reserved.

关键词： Critical success factors Enterprise engineering guidelines Performance measurement Service operations

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Design approach for additive manufacturing in spare part supply chains

arXiv

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arXiv 2020年

作者： de Brito, Filipe Marinho da Cruz Júnior, Gélson Frazzon, Enzo Morosini Basto, João Pedro Tavares Vieira Alcalá, Symone Gomes Soares School of Electrical Mechanical and Computer Engineering Federal University of Goiás GoiâniaGoiás74605-010 Brazil INESC P&D Brasil São Paulo11055-300 Brazil Graduate Program in Production Engineering Department of Production Engineering and Systems Federal University of Santa Catarina Florianópolis88040-900 Brazil Department of Industrial Engineering and Management Faculty of Engineering University of Porto Porto4200-465 Portugal INESC TEC - Technology Faculty of Engineering University of Porto Porto4200-465 Portugal Production Engineering Faculty of Sciences and Technology Federal University of Goiás Aparecida de Goiânia Goiás74968-755 Brazil

In the current industrial revolution, additive manufacturing (AM) embodies a promising technology that can enhance the effectiveness, adaptability, and competitiveness of supply chains (SCs). Moreover, it facilitates the development of distributed SCs, thereby enhancing product availability, inventory levels, and lead time. However, the wide adoption of AM in industrial SCs creates various challenges, leading to new difficulties for SC design. In this context, this paper proposes a new design approach to AM SCs using optimization methods. More specifically, the proposed approach, comprising the pmedian and mixed-integer linear programming models, considers the decision of deploying productive resources (3D printers) in specific locations of generic spare part SCs. The approach was evaluated in a real-world use case of an elevator maintenance service provider. The obtained results demonstrated the promising capabilities of the proposed design approach in managing the challenges arising from the forthcoming widespread use of 3D printers in manufacturing SCs. © 2020, CC-BY-NC-ND.

关键词： 3D printers

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Marangoni convection-driven laser fountains and waves on free surfaces of liquids

arXiv

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arXiv 2021年

作者： Lin, Feng Quraishy, Aamir Nasir Tong, Tian Li, Runjia Yang, Guang Mohebinia, Mohammadjavad Qiu, Yi Vishal, Talari Zhao, Junyi Zhang, Wei Zhong, Hong Zhang, Hang Zhou, Chaofu Tong, Xin Yu, Peng Hu, Jonathan Dong, Suchuan Liu, Dong Wang, Zhiming Schaibley, John R. Bao, Jiming Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China ChengduSichuan610054 China Department of Electrical and Computer Engineering University of Houston HoustonTX77204 United States Department of Physics University of Arizona TucsonAZ85721 United States James C. Wyant College of Optical Sciences University of Arizona TucsonAZ85721 United States Department of Mechanical Engineering University of Houston HoustonTX77204 United States Materials Science and Engineering Program University of Houston HoustonTX77204 United States School of Science Southwest Petroleum University ChengduSichuan610500 China Department of Electrical and Systems Engineering Washington University in St. Louis St. LouisMO63130 United States Department of Electrical & Computer Engineering Baylor University WacoTX76798 United States Department of Mathematics Purdue University West LafayetteIN47907 United States Department of Physics Texas Center for Superconductivity University of Houston HoustonTX77204 United States

It is well accepted that an outward Marangoni convection from a low surface tension region will make the surface depressed. Here, we report that this established perception is only valid for thin liquid films. Using surface laser heating, we show that in deep liquids a laser beam actually pulls up the fluid above the free surface generating fountains with different shapes. Whereas with decreasing liquid depth a transition from fountain to indentation with fountain-in-indentation is observed. Further, high-speed imaging reveals a transient surface process before steady elevation is formed, and this dynamic deformation is subsequently utilized to resonantly excite giant surface waves by a modulated laser beam. Computational fluid dynamics models reveal the underlying flow patterns and quantify the depth-dependent and time-resolved surface deformations. Our discoveries and techniques have upended the century-old perception and opened up a new regime of interdisciplinary research and applications of Marangoni-induced interface phenomena and optocapillary fluidic surfaces - the control of fluids with light. © 2021, CC BY.

关键词： Deformation

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An improved explicit scheme for whole-building hygrothermal simulation

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建筑模拟（英文版） 2018年第3期11卷 465-481页

作者： Suelen Gasparin Julien Berger Denys Dutykh Nathan Mendes Thermal Systems Laboratory Mechanical Engineering Graduate Program Pontifical Catholic University of Paraná Rua Imaculada Concei??o 1155 Curitiba - Paraná 80215-901 Brazil LAMA UMR 5127 CNRS Université Savoie Mont Blanc Campus Scientifique 73376 Le Bourget-du-Lac Cedex France Université Savoie Mont Blanc CNRS LOCIE F-73000 Chambéry France LAMA UMR 5127 CNRS Université Savoie Mont Blanc Campus Scientifique 73376 Le Bourget-du-Lac Cedex France Thermal Systems Laboratory Mechanical Engineering Graduate Program Pontifical Catholic University of Paraná Rua Imaculada Concei??o 1155 Curitiba - Paraná 80215-901 Brazil

Implicit schemes require important sub-iterations when dealing with highly nonlinear problems such as the combined heat and moisture transfer through porous building elements. The computational cost rises significantly when the whole-building is simulated, especially when there is important coupling among the building elements themselves with neighbouring zones and with HVAC (heating ventilation and air conditioning) systems. On the other hand, the classical Euler explicit scheme is generally not used because its stability condition imposes very fine time discretisation. Hence, this paper explores the use of an improved explicit approach—the DuFort–Frankel scheme—to overcome the disadvantage of the classical explicit one and to bring benefits that cannot be obtained by implicit methods. The DuFort–Frankel approach is first compared to the classical Euler implicit and explicit schemes to compute the solution of nonlinear heat and moisture transfer through porous materials. Then, the analysis of the DuFort–Frankel unconditionally stable explicit scheme is extended to the coupled heat and moisture balances on the scale of a one- and a two-zone building models. The DuFort–Frankel scheme has the benefits of being unconditionally stable, second-order accurate in time O(Δt2) and to compute explicitly the solution at each time step, avoiding costly sub-iterations. This approach may reduce the computational cost by twenty as wel as it may enable perfect synchronism for whole-building simulation and co-simulation.

关键词： heat and moisture transfer numerical methods finite-differences explicit schemes DuFort–Frankel scheme whole-building simulation

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Numerical Treatment of Parametric Gradient Problems in Source Term by New Difference Methods

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Journal of the Chinese Society of mechanical Engineers, Transactions of the Chinese Institute of Engineers, Series C/Chung-Kuo Chi Hsueh Kung Ch'eng Hsuebo Pao 2018年第6期39卷 609-618页

作者： Shieh, Tzong-Hann Li, Meng-Rong Li, Yu-Tso Chen, Yung-Ting Department of Aerospace and Systems Engineering Feng Chia University 100 Wenhwa Rd. Seatwen Taichung Taiwan Ph.D. Program of Mechanical and Aeronautical Engineering Feng Chia University 100 Wenhwa Rd. Seatwen Taichung Taiwan Department of Mathematical Sciences National Chengchi University 64 Sec. 2 ZhiNan Rd. Wenshan District Taipei Taiwan Department of Mechanical Engineering Minghsin University of Science and Technology No.1 Xinxing Rd. Xinfeng Hsinchu30401 Taiwan

In this paper, we expand the energy equation of unsteady Euler equations as the form of mixture gas and carry out the numerical resolution through the FVM to discuss the nonphysical oscillations near the contact discontinuity interface and shock wave. We resolve the equations by using the AUSMDV Riemann solver with different flux limiters, the FVM and the second-order with two-step discrete-time stepping method. For the source term in the investigated Euler equations with multi-species, we discuss the facing problem of for the numerical treatment of gradient in different type and test the non-physical oscillation problem by establishing a new applied method of gradient control. © 2018, Chinese mechanical engineering Society. All right reserved.

关键词： Euler equations

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