Optical tweezers are used for manipulation of micron-sized dielectric beads and cells. Some biological cells are vulnerable to photo damage if subjected to laser-based direct manipulation. In such cases, precise manip...
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Optical tweezers are used for manipulation of micron-sized dielectric beads and cells. Some biological cells are vulnerable to photo damage if subjected to laser-based direct manipulation. In such cases, precise manipulation of these cells can be accomplished by using gripper formations made up of silica beads, which are actuated by optical tweezers. Manual indirect manipulation of cells using grippers made of optically trapped beads is a time consuming process or sometimes just impossible. This paper presents an approach for automated micromanipulation using gripper formations and heuristic based path planning for collision-free transport of biological cells. The objective of the developed planner is to transport target cells to their respective goal positions in the minimum time. we evaluated the performance of different gripper formations in terms of gripper stability, speed of transport, and required laser power using experiments.
Optical Tweezers (OT) are used for highly accurate manipulations of biological cells. However, the direct exposure of cells to focused laser beam may negatively influence their biological functions. In order to overco...
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Optical Tweezers (OT) are used for highly accurate manipulations of biological cells. However, the direct exposure of cells to focused laser beam may negatively influence their biological functions. In order to overcome this problem, we generate multiple optical traps to grab and move a 3D ensemble of inert particles such as silica microspheres to act as a reconfigurable gripper for a manipulated cell. The relative positions of the microspheres are important in order for the gripper to be robust against external environmental forces and the exposure of high intensity laser on the cell to be minimized. In this paper, we present results of different gripper configurations, experimentally tested using our OT setup, that provide robust gripping as well as minimize laser intensity experienced by the cell. We developed a computational approach that allowed us to perform preliminary modeling and synthesis of the gripper configurations. The gripper synthesis is cast as a multi-objective optimization problem.
In this paper, we have proposed a congestion management scheme for smart grid infrastructures to control the power absorption from the grid in the presence of PHEVs connected to the distribution network. The decentral...
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ISBN:
(纸本)9781467327275
In this paper, we have proposed a congestion management scheme for smart grid infrastructures to control the power absorption from the grid in the presence of PHEVs connected to the distribution network. The decentralized solution that we have developed is based on game theory and is demonstrated to converge in a finite number of steps to a pure Nash equilibrium solution. This approach is implemented for managing the power absorbed from the grid and thereby the power bought from the grid through auctions taking place in a stochastic power and energy market. Various test cases have been developed based on the agents' strategies and also on the charging time and duration of PHEVs. The proposed approach was validated using these test cases, which were implemented in a multi agent framework.
A new analysis approach is developed for hand-arm vibration analysis of musculoskeletal disorders. At a given equilibrium point, the musculo-tendon system can be interpreted as a spring damper system. It is considered...
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A new analysis approach is developed for hand-arm vibration analysis of musculoskeletal disorders. At a given equilibrium point, the musculo-tendon system can be interpreted as a spring damper system. It is considered that the Flexor Digitorum Profundus (FDP) and Lumbrical (LU) are participating in the response to the vibration force. The study shows that realistic muscle models should be included in the vibration analysis of the hand-arm exposed to tool vibration. The hand-arm system is found to have a redundancy in muscles because it has many more muscles than the minimum number required to establish equilibrium in gripping. An important observation is that bigger extrinsic muscles carry most of the static load to generate the grip force, and smaller muscles carry most tool vibration force at high frequencies.
The vibration response of small arteries is studied by modeling the system as an elastic tube filled with incompressible fluid embedded in an elastic foundation. The entire artery system is represented by a series of ...
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The vibration response of small arteries is studied by modeling the system as an elastic tube filled with incompressible fluid embedded in an elastic foundation. The entire artery system is represented by a series of circuits and the segments of the artery system is considered to be small oscillatory dynamic systems connected serially by the fluid impedance. The resonance frequency of the digital artery is calculated with 0.1mm thickness, 0.49 Poisson's ratio, 15 MPa Young's modulus and 50mm length of the vessel. When the cochlea are subjected to sound of a given frequency. the basilar membrane vibrates with large amplitude at a particular position, and the position depends on the frequency of the sound. A very interesting observation is that when the input is from the large diameter side, the same artery system does not show any spatial resonance.
A gauge block evaluation system was developed and its uncertainty estimation was performed for distance determination using the repetition interval of a femtosecond optical frequency comb - the national standard tool ...
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Functional electrical stimulation (FES) is able to restore motor function of spinal cord injured (SCI) patients. To make adaptive FES control taking into account the actual muscle state with muscular feedback informat...
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ISBN:
(纸本)9781467317375
Functional electrical stimulation (FES) is able to restore motor function of spinal cord injured (SCI) patients. To make adaptive FES control taking into account the actual muscle state with muscular feedback information, torque estimation and prediction are important to be provided beforehand. Evoked EMG (eEMG) has been found to be highly correlated with FES-induced torque under various muscle conditions, indicating that it can be an useful tool for torque/force prediction. To better construct the relationship between eEMG and stimulated muscular torque, nonlinear-arx-type (NARX-type) model is preferred. This paper presents and exploits a NARX-type recurrent neural network (NARX-RNN) model for identification and prediction of FES-induced muscular dynamics with eEMG. Such NARX-RNN model is with a novel architecture for prediction, with robust prediction performance. To make fast convergence for identification of such NARX-RNN, directly-learning pattern is exploited during the learning phase. Due to difficulty of choosing a proper forgetting factor of Kalman filter for predicting time-variant torque with eEMG, such NARX-RNN may be considered to be a better alternative as torque predictor. Data gathered from two SCI patients is used to evaluate the proposed NARX-RNN model. The NARX-RNN model shows promising estimation and prediction performance only based on eEMG.
Artificial bee colony (ABC) is an optimization algorithm inspired on the intelligent behavior of honey bee swarms. It is suitable to be applied when mathematical techniques are impractical or provide suboptimal soluti...
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ISBN:
(纸本)9781467312073
Artificial bee colony (ABC) is an optimization algorithm inspired on the intelligent behavior of honey bee swarms. It is suitable to be applied when mathematical techniques are impractical or provide suboptimal solutions. As a population-based algorithm, the ABC suffers on large execution times specifically for embedded optimization problems with computational limitations. For that we propose a hardware parallel architecture of the opposition-based ABC algorithm (HPOABC) that facilitates the implementation in Field programmable Gate Arrays (FPGAs). Numerical simulations using four well-known benchmark problems demonstrate that the opposition-based approach allows the algorithm to improve its functionality, preserving the swarm diversity. Additionally, synthesis results point outs that the HPOABC architecture is effectively mapped in hardware and is suitable for embedded applications.
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