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Effective treatment of chronic radiation proctitis using radiofrequency ablation

Therapeutic Advances in Gastroenterology 2009年第3期2卷 149-156页

作者： Zhou, Chao Adler, Desmond C. Chen, Yu Tsai, Tsung-Han Fujimoto, James G. Becker, Laren Figueiredo, Marisa Mashimo, Hiroshi Schmitt, Joseph M. Department of Electrical Engineering and Computer Science Research Laboratory of Electronics Massachusetts Institute of Technology Cambridge MA United States VA Boston Healthcare System Harvard Medical School MA United States LightLab Imaging Inc. Westford MA United States

Endoscopic argon plasma coagulation and bipolar electrocautery are currently preferred treatments for chronic radiation proctitis, but ulcerations and strictures frequently occur. Radiofrequency ablation (RFA) has been successful for mucosal ablation in the esophagus. Here we report the efficacy of RFA with the BarRx Halo⁹⁰ system in three patients with bleeding from chronic radiation proctitis. In all cases, the procedure was well tolerated and hemostasis was achieved after 1 or 2 RFA sessions. Re-epithelialization of squamous mucosa was observed over areas of prior hemorrhage. No stricturing or ulceration was seen on follow-up up to 19 months after RFA treatment. Real-time endoscopic optical coherence tomography (EOCT) visualized epithelialization and subsurface tissue microvasculature pre- and post-treatment, demonstrating its potential for follow-up assessment of endoscopic therapies. © 2009, SAGE Publications. All rights reserved.

关键词： Chronic radiation proctitis Endoscopic optical coherence tomography (EOCT) Endoscopic therapy Lower gastrointestinal bleeding Radiofrequency ablation (RFA)

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A sample identification and tracking system for biobanks

A sample identification and tracking system for biobanks

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2009 22nd IEEE International Symposium on computer-Based medical Systems, CBMS 2009

作者： Zarabzadeh, Atieh Hayati, Farzad William G Watson, R. Bradley, Geoff Grimson, Jane Centre for Health Informatics Department of Computer Science Trinity College Dublin United States The Department of Electronic Electrical and Computer Engineering University of Birmingham United Kingdom UCD School of Medicine and Medical Science UCD Conway Institute of Biomo Lecular and Biomedical Research University College Dublin United States Trinity Centre for High Performance Computing Trinity College Dublin United States

ISBN: (纸本)9781424448784

The discovery of biomarkers and the underlying causes of diseases are enabled through the analysis of biological samples and data stored in biobanks. Biological samples and their associated data are expensive to collect and maintain, and it is important to store and manage them efficiently. During processing, samples and data go through a number of procedures and techniques, which are often in different locations and by individuals with different access permissions. It is essential to maintain the link between the samples and their associated data throughout the processes they undergo. This paper presents a novel system of tracking samples and data from collection through processing to storage and retrieval, which is based on Radio Frequency Identification (RFID) technology. This system ensures the security and reliability of sample data as well as locationindependent recording and updating of sample data, as they move along the workflow. ©2009 IEEE.

关键词： Radio frequency identification (RFID)

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TSS: Applying two-stage sampling in micro-architecture simulations

TSS: Applying two-stage sampling in micro-architecture simul...

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International Symposium on Modeling, Analysis and Simulation of computer and Telecommunication Systems (MASCOTS)

作者： Zhibin Yu Hai Jin Jian Chen Lizy K. John Service Computing Technology and System Laboratory Cluster and Grid Computing Laboratory Huazhong University of Science and Technology Wuhan China Department of Electrical and Computer Engineering University of Texas Austin Austin TX USA

ISBN: (纸本)9781424449279

Accelerating micro-architecture simulation is becoming increasingly urgent as the complexity of workload and simulated processor increases. This paper presents a novel two-stage sampling (TSS) scheme to accelerate the sampling-based simulation. It firstly selects some large samples from a dynamic instruction stream as candidates of detail simulation and then samples some small groups from each selected first stage sample to do detail simulation. Since the distribution of standard deviation of cycle per instruction (CPI) is insensitive to microarchitecture, TSS could be used to speedup design space exploration by splitting the sampling process into two stages, which is able to remove redundant instruction samples from detail simulation when the program is in stable program phase (standard deviation of CPI is near zero). It also adopts systematic sampling to accelerate the functional warm-up in sampling simulation. Experimental results show that, by combining these two techniques, TSS achieves an average and maximum speedup of 1.3 and 2.29 over SMARTS, with the average CPI relative error is less than 3%. TSS could significantly accelerate the time consuming iterative early design evaluation process.

关键词： Sampling methods Computational modeling Acceleration Microarchitecture computer simulation Redundancy Grid computing Space exploration computer errors Process design

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Brain tissue classification using independent vector analysis (IVA) for magnetic resonance image

Brain tissue classification using independent vector analysi...

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2009 9th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2009

作者： Chiou, Yaw-Jiunn Chen, Hsiang-Min Chai, Jyh Wen Chen, Clayton Chi-Chang Ouyang, Yen-Chieh Su, Wu-Chung Yang, Ching-Wen Lee, San-Kan Chang, Chein-I. Department of Electrical Engineering National Chung Hsing University Taichung Taiwan Department of Radiology College of Medicine China Medical University Taichung Taiwan School of Medicine National Yang-Ming University Taipei Taiwan Department of Radiology Taichung Veterans General Hospital Taichung Taiwan Department of Radiological Technology Central Taiwan University of Science and Technology Taichung 406 Taiwan Computer Center Taichung Veterans General Hospital Taichung 407 Taiwan Remote Sensing Signal and Image Processing Laboratory Department of Computer Science and Electrical Engineering University of Maryland Baltimore County Baltimore MD 21250 United States

ISBN: (纸本)9780769536569

The purpose of this study is to present a new method, independent vector analysis (IVA), by extending independent component analysis (ICA) of univariate source signals to multivariate source signals on Magnetic Resonance Imaging (MRI). IVA is utilized to relief the limitation of the conventional ICA approach. The proposed method can resolve the permutation problem during individual ICA runs for group brain MR images. The proposed IVA method in conjunction with support vector machine (SVM), we can effectively separate the different part of gray, white matter and cerebrospinal fluid (CSF) from brain soft tissues. In order to demonstrate the proposed IVA-SVM method, experiments are conducted for performance analysis and evaluation. Simulation results show that using IVA can greatly release from the problem cause from traditional ICA to the situation of analyzing inconsistent results of MR image. © 2009 IEEE.

关键词： Magnetic resonance imaging

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An automatic computer-aided detection system for meniscal tears on magnetic resonance images

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IEEE Transactions on medical Imaging 2009年第8期28卷 1308-1316页

作者： Ramakrishna, Bharath Liu, Weimin Saiprasad, Ganesh Safdar, Nabile Chang, Chein-I Siddiqui, Khan Kim, W. Siegel, Eliot Chai, Jyh-Wen Chen, Clayton Chi-Chang Lee, San-Kan Remote Sensing Signal and Image Processing Laboratory Department of Computer Science and Electrical Engineering University of Maryland Baltimore MD 21250 United States University of Maryland School of Medicine Baltimore MD 21201 United States Department of Electrical Engineering and Environmental Restoration Disaster Reduction Research Center National Chung Hsing University Taichung 402 Taiwan VA Maryland Health Care System Baltimore MD 21201 United States Hospital of the University of Pennsylvania Philadelphia PA 19104 United States Department of Radiology College of Medicine China Medical University Taichung 404 Taiwan Department of Radiology Taichung Veterans General Hospital Taichung 40705 Taiwan Department of Radiological Technology Central Taiwan University of Science and Technology Taichung 406 Taiwan Department of Radiology Taichung Veterans General Hospital Taichung 407 Taiwan

Knee-related injuries including meniscal tears are common in both young athletes and the aging population, and require accurate diagnosis and surgical intervention when appropriate. With proper techniques and radiologists' experienced skills, confidence in detection of meniscal tears can be quite high. This paper develops a novel computer-aided detection (CAD) diagnostic system for automatic detection of meniscal tears in the knee. Evaluation of this CAD system using an archived database of images from 40 individuals with suspected knee injuries indicates that the sensitivity and specificity of the proposed CAD system are 83.87% and 75.19%, respectively, compared to the mean sensitivity and specificity of 77.41% and 81.39%, respectively, obtained by experienced radiologists in routine diagnosis without using the CAD. The experimental results suggest that the developed CAD system has great potential and promise in automatic detection of both simple and complex meniscal tears of the knee. © 2009 IEEE.

关键词： Magnetic resonance imaging

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A subject-specific radio propagation study in wireless body area networks

A subject-specific radio propagation study in wireless body ...

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Antennas and Propagation Conference, LAPC, Loughborough

作者： Yan Zhao Andrea Sani Yang Hao Su-lin Lee Guang-zhong Yang School of Electronic Engineering and Computer Science Queen''s Mary University of London London UK Department of Computing Imperial College London Royal Society Wolfson Foundation Medical Image Computing Laboratory London UK

ISBN: (纸本)9781424427208

This paper presents a study of subject-specific radio channels in wireless body area networks (WBANs). The simulation tool is based on a parallel finite-difference time-domain method (FDTD) and is well suited to model radio propagations around complex, inhomogeneous objects including human bodies in WBAN. It is found from our study that radio channel characteristics in WBAN are subject specific when the received signal mainly contains the contribution of creeping waves around the human body.

关键词： Radio propagation Body sensor networks Biological system modeling Finite difference methods Time domain analysis Humans Solid modeling computer networks Computational modeling Maxwell equations

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Ultrahigh speed Spectral / Fourier domain OCT imaging in ophthalmology

Ultrahigh speed Spectral / Fourier domain OCT imaging in oph...

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European Conferences on Biomedical Optics

作者： Potsaid, Benjamin Gorczynska, Iwona Srinivasan, Vivek J. Chen, Yueli Liu, Jonathan Jiang, James Cable, Alex Duker, Jay S. Fujimoto, James G. Department of Electrical Engineering and Computer Science Research Laboratory of Electronics Massachusetts Institute of Technology Cambridge MA 02139 United States New England Eye Center and Tufts Medical Center Tufts University Boston MA United States Advanced Imaging Group Thorlabs Inc. Newton NJ 07860 United States

ISBN: (纸本)9780819476487

Ultrahighs peed Spectral/Fourier domain ophthalmic OCT imaging at 70, 000-312,500 a xial scansper second is demonstrated using a high speed CMOS camera at 800 nm. Comparative imaging results of the fovea illustrate the performance tradeoffs between different imaging speeds and spectrometer configurations. Dense 3 Dvolumetric acquisitions show minimal motion artifacts when acquired at 250,000 axial scans per second. The porous structure of the lamina cribrosa is shown in enface images extracted from a densevol umetric acquisition of the optical nerve head acquired at 106, 382 a xial scans persecond. Rapid repeated volume imaging (4D-OCT) shows blood flow in retinal capillaries. Boundaries of the capillary network are enhanced by motion contrast. 3D volumetric data acquired at 49,000 axial scans persecond using an InGaAs camera at 1050 nm is compared to volumetric data acquired at 101, 010 axial scans per second using a CMOS camera at 800nm. Averaging of adjacent cross sectional scans in the volume is shown to increase contrast in the images and reduce speckle. The enhanced penetration of the 1050 nm compared to the 800 nm OCT im aging system is shown. Dense 2D/3 D data sets and 4D-OCT repeated volume imaging pro mise altern ative methods for diagnosis and monitoring of disease. © 2009 SPIE-OSA.

关键词： Optical tomography

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AAAI 2008 workshop reports

AAAI 2008 workshop reports

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作者： Anand, Sarabjot Singh Bunescu, Razvan Carvcdho, Vitor Chomicki, Jan Conitzer, Vincent Cox, Michael T. Dignum, Virginia Dodds, Zachary Dredze, Mark Furcy, David Gabrilovich, Evgeniy Göker, Mehmet H. Guesgen, Hans Hirsh, Haym Jannach, Dietmar Junker, Ulrich Ketter, Wolfgang Kobsa, Alfred Koenig, Sven Lau, Tessa Lewis, Lundy Matson, Eric Metzler, Ted Mihalcea, Rada Mobasher, Bamshad Pineau, Joelle Poupart, Pascal Raja, Anita Ruml, Wheeler Sadeh, Norman Shani, Guy Shapiro, Daniel Smith, Trey Taylor, Matthew E. Wagstaff, Kiri Walsh, William Zhou, Rong Department of Computer Science University of Warwick United Kingdom School of Electrical Engineering and Computer Science Ohio University United States Microsoft Live Labs United States computer science and engineering University at Buffalo United States Computer science and economics Duke University United States Intelligent Computing group of BBN Technologies Utrecht University Netherlands Department of Computer science Harvey Mudd College United States University of Pennsylvania United States University of Wisconsin United States Yahoo Research PricewaterhouseCoopers Center for Advanced Research United States Department of Computer science School of Engineering and Advanced Technology Massey University New Zealand Departent of Computer science Rutgers University United States Department of Computer Science Dortmund University of Technology. Germany ILOG Rotterdam School of Management Erasmus University Netherlands Donald Bren School of Information and Computer Sciences University of California Irvine United States Depatrment of Computer science University of Southern California United States IBM Almaden Research Center United States Department of Computer Information Technology Southern New Hampshire University United States Computer and Information Technology Program College of Technology Purdue University United States Hughes Program for Religion and Science Dialogue Oklahoma City University United States Department of Computer Science and Engineering University of North Texas United States School of Computing DePaul University United States Department of Computer Science McGill University Canada School of Computer Science University of Waterloo Canada Department of Software and Information Systems University of North Carolina Charlotte United States University of New Hampshire United States Microsoft Research Institute for the Study of Learning and Expertise Applied Reactivity Inc. United States NASA Ames Research Center Carnegie Mellon University West

AAAI was pleased to present the AAAI-08 Workshop Program, held Sunday and Monday, July 13-14, in Chicago, Illinois, USA. The program included the following 15 workshops: Advancements in POMDP Solvers;AI Education Workshop Colloquium;Coordination, Organizations, Institutions, and Norms in Agent Systems, Enhanced Messaging;Human Implications of Human-Robot Interaction;Intelligent Techniques for Web Personalization and Recommender Systems;Metareasoning: Thinking about Thinking;Multidisciplinary Workshop on Advances in Preference Handling;Search in Artificial Intelligence and Robotics;Spatial and Temporal Reasoning;Trading Agent Design and Analysis;Transfer Learning for Complex Tasks;What Went Wrong and Why: Lessons from AI Research and Applications;and Wikipedia and Artificial Intelligence: An Evolving Synergy. Copyright © 2009, Association for the Advancement of Artificial Intelligence. All rights reserved.

关键词： Human robot interaction

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Reports of the AAAI 2009 spring symposia

Reports of the AAAI 2009 spring symposia

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作者： Bao, Jie Bojars, Uldis Choudhury, Tanzeem Ding, Li Greaves, Mark Kapoor, Ashish Louchart, Sandy Mehta, Manish Nebel, Bernhard Nirenburg, Sergei Oates, Tim Roberts, David L. Sanfilippo, Antonio Stojanovic, Nenad Stubbs, Kristen Thomaz, Andrea L. Tsui, Katherine Woelfl, Stefan Tetherless World Constellation Rensselaer Polytechnic Institute United States Social Software Unit of DERI Galway Ireland Computer Science Department Dartmouth College United States Knowledge Systems at Vulcan Inc United States Adaptive Systems and Interaction Group Microsoft Research Redmond United States School for Mathematics and Computer Sciences Heriot-Watt University United Kingdom School ot Interactive Computing Georgia Institute of Technology United States Department of Computer Science University of Freiburg Germany Computer Science and Electrical Engineering Department University of Maryland Baltimore County United States Pacific Northwest National Laboratory Richland WA United States University of Karlsruhe Germany IRobot Corporation United States University of Massachusetts Lowell United States

The Association for the Advancement of Artificial Intelligence, in cooperation with Stanford University's department of computer science, was pleased to present the 2009 Spring Symposium Series, held Monday through Wednesday, March 23-25, 2009, at Stanford University. The titles of the nine symposia were Agents That Learn from Human Teachers, Benchmarking of Qualitative Spatial and Temporal Reasoning Systems, Experimental Design for Real- World Systems, Human Behavior Modeling, Intelligent Event Processing, Intelligent Narrative Technologies II, Learning by Reading and Learning to Read, Social Semantic Web: Where Web 2.0 Meets Web 3.0, and Technosocial Predictive Analytics. The goal of the Agents That Learn from Human Teachers symposium was to investigate how we can enable software and robotics agents to leam from real-time interaction with an everyday human partner. The aim of the Benchmarking of Qualitative Spatial and Temporal Reasoning Systems symposium was to initiate the development of a problem repository in the field of qualitative spatial and temporal reasoning and identify a graded set of challenges for future midterm and long-term research. The Experimental Design symposium discussed the challenges of evaluating AI systems. The Human Behavior Modeling symposium explored reasoning methods for understanding various aspects of human behavior, especially in the context of designing intelligent systems that interact with humans. The Intelligent Event Processing symposium discussed the need for more Al-based approaches in event pro-cessing and defined a kind of research agenda for the field, coined as intelligent complex event processing (iCEP). The Intelligent Narrative Technologies IIAAAI symposium discussed innovations, progress, and novel techniques in the research domain. The Learning by Reading and Learning to Read symposium explored two aspects of making natural language texts semantically accessible to, and processable by, machines. The Social Semantic

关键词： Benchmarking

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Recent advances in Cr: Colquiriite laser technology

Recent advances in Cr: Colquiriite laser technology

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IEEE Photonics Conference (IPC)

作者： Umit Demirbas Sava Sakadžić Kyung-Han Hong Jonathan R. Birge Duo Li Hyunil Byun Peter Fendel Gale S. Petrich Leslie A. Kolodziejski David A. Boas Alphan Sennaroglu Franz X. Kćrtner James G. Fujimoto Department of Electrical Engineering and Computer Science MIT Cambridge MA USA MGH/MIT/HMS Athinuola A. Martinos Center for Biomedical Imaging Harvard Medical School Charlestown MA USA Laser Research Laboratory Department of Physics Koç University Istanbul Turkey Department of Electrical Engineering and Computer Science MIT 77 Massachusetts Avenue Cambridge 02139 USA

ISBN: (纸本)9781424436804

We summarize recent progress in low-cost and highly-efficient Cr:Colquiriite laser technology. Pumping with inexpensive single-mode diodes, 270-mW of output power and a total tunability from 754 to 1042 nm were demonstrated in continuous-wave operation. In mode-locked operation, 100-fs pulses with 50-nJ pulse energy were demonstrated.

关键词： Chromium Pump lasers Laser mode locking Diodes Power generation Laser excitation Laser tuning Mirrors Laser theory Costs

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