检索结果-内蒙古大学图书馆

1st International Conference on Computer Science and Artificial Intelligence, ICCSAI 2021

作者： Jimmy Cenggoro, Tjeng Wawan Pardamean, Bens Bina Nusantara University BINUS Graduate Program-Master of Computer Science Program Computer Science Department Jakarta11480 Indonesia Bina Nusantara University School of Computer Science Computer Science Department Jakarta11480 Indonesia Bina Nusantara University Bioinformatics and Data Science Research Center Jakarta11480 Indonesia

ISBN: (纸本)9781728133331

Tuberculosis (TB) is one of the top ten reasons for death from an infectious agent. Although TB is curable and preventable, delay in diagnosis and treatment can lead the patient to death. Advancements in computer-Aided diagnosis (CAD), particularly in medical images classification, significantly contribute to early TB detection. The current state-of-Art CAD for medical images classification applications using a method base on deep learning techniques. The problem faced in this deep learning technique is that, in general, it only uses a single modal for the model. In contrast, in medical practice, the data used for TB analysis not only focuses on images but also includes clinical data such as demographics, patient assessments, and lab test results. This systematic literature review describes different deep learning methods using single modal or multimodal techniques that combined images with other clinical data. We conducted a systematic search on Springer, PubMed, ResearchGate, and google scholar for original research leveraging deep learning for Pulmonary TB detection. © 2021 IEEE.

关键词： Computer aided diagnosis

来源：评论

学校读者我要写书评

暂无评论

Using ensemble learning and hierarchical strategy to predict the outcomes of ESWL for upper ureteral stone treatment

引用

Computers in Biology and Medicine 2024年 179卷 108904-108904页

作者： Chen, Chi-Wei Liu, Wayne-Young Huang, Lan-Ying Chu, Yen-Wei Graduate Degree Program of Smart Healthcare & Bioinformatics I-Shou University Kaohsiung City Taiwan Department of Biomedical Engineering I-Shou University Kaohsiung City Taiwan Doctoral Program in Medical Biotechnology National Chung Hsing University Taichung City Taiwan Department of Urology Jen-Ai Hospital Taichung City Taiwan Graduate Institute of Genomics and Bioinformatics National Chung Hsing University Taichung City Taiwan Institute of Molecular Biology National Chung Hsing University Taichung City Taiwan Agricultural Biotechnology Center National Chung Hsing University Taichung City Taiwan Rong Hsing Research Center for Translational Medicine Taichung City Taiwan Ph. D Program in Medical Biotechnology National Chung Hsing University Taichung City Taiwan Taichung402 Taiwan

Urinary tract stones are a common and frequently recurring medical issue. Accurately predicting the success rate after surgery can help avoid ineffective medical procedures and reduce unnecessary healthcare costs. This study collected data from patients with upper ureter stones who underwent extracorporeal shock wave lithotripsy, including cases of successful as well as unsuccessful stone removal after the first and second lithotripsy procedures, and constructed prediction systems for the outcomes of the first and second lithotripsy procedures. Features were extracted from three categories of information: patient characteristics, stone characteristics, and extracorporeal shock wave lithotripsy machine data, and additional features were created using Feature Creation. Finally, the impact of features on the models was analyzed using six methods to calculate feature importance. Our prediction model for the first lithotripsy, selected from among 43 methods and seven ensemble learning techniques, achieves an AUC of 0.91. For the second lithotripsy, the AUC reaches 0.76. The results indicate that the detailed and binary information provided by patients regarding their history of stone experiences contributes differently to the predictive accuracy of the first and second lithotripsy procedures. The prediction tool is available at https://***/ks. © 2024

关键词： Machine learning

来源：评论

学校读者我要写书评

暂无评论

Mutual dependency between lncRNA LETN and protein NPM1 in controlling the nucleolar structure and functions sustaining cell proliferation

引用

细胞研究（英文版） 2021年第6期31卷 664-683页

作者： Xianteng Wang Xiaolin Hu Wanlu Song Hui Xu Zhengtao Xiao Rongyao Huang Qingran Bai Fan Zhang Yongzhen Chen Yu Liu Jianhuo Fang Xin Li Qin Shen Haitao Zhao Xuerui Yang MOE Key Laboratory of Bioinformatics Tsinghua UniversityBeijing 100084China Center for Synthetic & Systems Biology Tsinghua UniversityBeijing 100084China School of Life Sciences Tsinghua UniversityBeijing 100084China MOE Key Laboratory of Bioinformatics Tsinghua UniversityBeijing 100084China Center for Synthetic & Systems Biology Tsinghua UniversityBeijing 100084China School of Life Sciences Tsinghua UniversityBeijing 100084China Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Science Beijing 100084China Brain and Spinal Cord Innovative Research Center of Tongji Hospital School of Life Sciences and TechnologyTongji University and Frontier Science Research Center for Stem Cells of Ministry of EducationShanghai 200092China Department of Liver Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC)Beijing 100730China

Fundamental processes such as ribosomal RNA synthesis and chromatin remodeling take place in the nucleolus,which is hyperactive in fast-proliferating *** sophisticated regulatory mechanism underlying the dynamic nucleolar structure and functions is yet to be fully *** present study uncovers the mutual functional dependency between a previously uncharacterized human long non-coding RNA,which we renamed LETN,and a key nucleolar protein,***,being upregulated in multiple types of cancer,LETN resides in the nucleolus via direct binding with *** plays a critical role in facilitating the formation of NPM1 pentamers,which are essential building blocks of the nucleolar granular component and control the nucleolar *** of LETN or NPM1 led to similar and profound changes of the nucleolar morphology and arrest of the nucleolar functions,which led to proliferation inhibition of human cancer cells and neural progenitor ***,this inter-dependency between LETN and NPM1 is associated with the evolutionarily new variations of NPM1 and the coincidental emergence of LETN in higher *** propose that this human-specific protein-lncRNA axis renders an additional yet critical layer of regulation with high physiological relevance in both cancerous and normal developmental processes that require hyperactive nucleoli.

关键词： Cell division Long non-coding RNAs

来源：评论

学校读者我要写书评

暂无评论

Lightweight Pedestrian Detection through Guided Filtering and Deep Learning 10

Lightweight Pedestrian Detection through Guided Filtering an...

引用

10th IEEE Global Conference on Consumer Electronics, GCCE 2021

作者： Muchtar, Kahlil Saddami, Khairun Bintang, Akhyar Cenggoro, Tjeng Wawan Pardamean, Bens Lin, Chih-Yang Ernita, Tia Universitas Syiah Kuala Department of Electrical And Computer Engineering Aceh Indonesia Universitas Syiah Kuala Department of Electrical And Computer Engineering Aceh Indonesia Bina Nusantara University School of Computer Science Bina Nusantara University Bioinformatics And Data Science Research Center Computer Science Department Jakarta Indonesia Bina Nusantara University BINUS Graduate Program-Master of Computer Science Program Bina Nusantara University Bioinformatics And Data Science Research Center Computer Science Department Jakarta Indonesia Yuan-Ze University Department of Electrical And Engineering Taoyuan Taiwan

ISBN: (纸本)9781665436762

In this paper, we propose a novel approach to locate and detect moving pedestrians in a video. Our proposed method first locates the region of interest (ROI) using a background subtraction algorithm based on guided filtering. This novel background subtraction algorithm allows our method to also filter unexpected noises at the same time, which could benefit the performance of our proposed method. Subsequently, the pedestrians are detected using YOLOv3 within the provided ROI. Our experiments showed that the proposed method has a competitive performance in the CDNET2014 dataset with a fast-processing time. © 2021 IEEE.

关键词： Convolutional neural networks

来源：评论

学校读者我要写书评

暂无评论

Confidentiality. Integrity, and Availability (CIA) Approach for Private Dataset Management System Design

Confidentiality. Integrity, and Availability (CIA) Approach ...

引用

Information Technology and Digital Applications (ICITDA), IEEE International Conference on

作者： Mahmud Isnan Gregorius Natanael Elwirehardja Dedy Ariansyah Reza Rahutomo Bens Pardamean Computer Science Department School of Computer Science Bina Nusantara University Jakarta Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Information Systems Department School of Information Systems Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331510732

ISBN: (纸本)9798331510749

Dataset management systems are essential for assisting research and development (R&D) organizations in applying data governance protocols, especially in managing the utilization of datasets. In R&D, datasets are vital sources for producing analysis, machine learning prediction, and supporting decision-making. As such, it is important to deploy dataset management systems with considerations regarding the aspects of Confidentiality, Integrity, and Availability (CIA) which is a design principle that emphasized information protection and collaboration facilitation among dataset users. The study proposed an analysis and a design for a dataset management system that takes CIA aspects into account. In the future, the proposed design will be utilized as a benchmark for building a dataset management system. In this study, the Waterfall method was adopted. A use case diagram, an ERD (Entity Relationship Diagram), and an activity diagram were constructed in the design stage. In the project implementation stage, the Laravel framework including Laravel Jetstream was considered to be used.

关键词： Protocols Data security Decision making Organizations Machine learning Encryption Protection Information technology Research and development System analysis and design

来源：评论

学校读者我要写书评

暂无评论

High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials

引用

ChemBioChem 2022年第17期23卷 e202200310-e202200310页

作者： Solares, Maria J. Jonaid, G.M. Luqiu, William Y. Berry, Samantha Khadela, Janki Liang, Yanping Evans, Madison C. Pridham, Kevin J. Dearnaley, William J. Sheng, Zhi Kelly, Deborah F. Molecular Cellular and Integrative Biosciences Graduate Program Huck Institutes of the Life Sciences Pennsylvania State University University Park 16802 PA United States Bioinformatics and Genomics Graduate Program Huck Institutes of the Life Sciences Pennsylvania State University University Park 16802 PA United States Department of Biomedical Engineering Pennsylvania State University University Park 16802 PA United States Center for Structural Oncology Pennsylvania State University University Park 16802 PA United States Department of Electrical and Computer Engineering Duke University Durham 27708 NC United States Fralin Biomedical Research Institute at VTC Virginia Tech Roanoke 24016 VA United States

Mutations in tumor suppressor genes, such as Tumor Protein 53 (TP53), are heavily implicated in aggressive cancers giving rise to gain- and loss-of-function phenotypes. While individual domains of the p53 protein have been studied extensively, structural information for full-length p53 remains incomplete. Functionalized microprocessor chips (microchips) with properties amenable to electron microscopy permitted us to visualize complete p53 assemblies for the first time. The new structures revealed p53 in an inactive dimeric state independent of DNA binding. Residues located at the protein-protein interface corresponded with modification sites in cancer-related hot spots. Changes in these regions may amplify the toxic effects of clinical mutations. Taken together, these results contribute advances in technology and imaging approaches to decode native protein models in different states of activation. © 2022 Wiley-VCH GmbH.

关键词： cancer electron microscopy microchips p53, molecular modeling

来源：评论

学校读者我要写书评

暂无评论

Targeting protein-protein interaction interfaces with antiviral N protein inhibitor in SARS-CoV-2

引用

Biophysical Journal 2024年第4期123卷 478-488页

作者： Hong, Jhen-Yi Lin, Shih-Chao Kehn-Hall, Kylene Zhang, Kai-Min Luo, Shun-Yuan Wu, Hung-Yi Chang, Sui-Yuan Hou, Ming-Hon Institute of Genomics and Bioinformatics and Department of Life Sciences National Chung Hsing University Taichung Taiwan Bachelor Degree Program in Marine Biotechnology College of Life Sciences National Taiwan Ocean University Keelung Taiwan Department of Biomedical Sciences and Pathobiology Virginia-Maryland College of Veterinary Medicine Virginia Polytechnic Institute and State University Blacksburg VA United States Center for Emerging Zoonotic and Arthropod-borne Pathogens Virginia Polytechnic Institute and State University Blacksburg VA United States Department of Chemistry National Chung Hsing University Taichung Taiwan Graduate Institute of Veterinary Pathobiology College of Veterinary Medicine National Chung Hsing University. Taichung Taiwan Department of Clinical Laboratory Sciences and Medical Biotechnology College of Medicine National Taiwan University Taipei Taiwan PhD Program in Medical Biotechnology National Chung Hsing University Taichung Taiwan Biotechnology Center National Chung Hsing University Taichung Taiwan

Coronaviruses not only pose significant global public health threats but also cause extensive damage to livestock-based industries. Previous studies have shown that 5-benzyloxygramine (P3) targets the Middle East respiratory syndrome coronavirus (MERS-CoV) nucleocapsid (N) protein N-terminal domain (N-NTD), inducing non-native protein-protein interactions (PPIs) that impair N protein function. Moreover, P3 exhibits broad-spectrum antiviral activity against CoVs. The sequence similarity of N proteins is relatively low among CoVs, further exhibiting notable variations in the hydrophobic residue responsible for non-native PPIs in the N-NTD. Therefore, to ascertain the mechanism by which P3 demonstrates broad-spectrum anti-CoV activity, we determined the crystal structure of the SARS-CoV-2 N-NTD:P3 complex. We found that P3 was positioned in the dimeric N-NTD via hydrophobic contacts. Compared with the interfaces in MERS-CoV N-NTD, P3 had a reversed orientation in SARS-CoV-2 N-NTD. The Phe residue in the MERS-CoV N-NTD:P3 complex stabilized both P3 moieties. However, in the SARS-CoV-2 N-NTD:P3 complex, the Ile residue formed only one interaction with the P3 benzene ring. Moreover, the pocket in the SARS-CoV-2 N-NTD:P3 complex was more hydrophobic, favoring the insertion of the P3 benzene ring into the complex. Nevertheless, hydrophobic interactions remained the primary stabilizing force in both complexes. These findings suggested that despite the differences in the sequence, P3 can accommodate a hydrophobic pocket in N-NTD to mediate a non-native PPI, enabling its effectiveness against various CoVs. © 2024 Biophysical Society

关键词：

来源：评论

学校读者我要写书评

暂无评论

Determining Variables Associated with Annual Oil Palm Yield: An Explainable Gradient Boosting Approach

引用

Procedia Computer Science 2023年 227卷 262-271页

作者： Gregorius Natanael Elwirehardja Teddy Suparyanto Miftakhurrokhmat Bens Pardamean Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia 11480 Computer Science Department School of Computer Science Bina Nusantara University Jakarta Indonesia 11480 Faculty of Agricultural Technology Institute of Agriculture STIPER Yogyakarta Indonesia 55282 Faculty of Industrial Technology Universitas Islam Indonesia Yogyakarta Indonesia 55584 Computer Science Department BINUS Graduate Program – Master of Computer Science Program Bina Nusantara University Jakarta Indonesia 11480

With the growing demands for Precision Agriculture (PA) in Indonesia, researchers have evaluated the utilization of Machine Learning for predicting oil palm yields and determining variables affecting them. Previous studies showed that meteorological variables, including rainfalls and wind speed, are associated with oil palm yields. In this research, the Extreme Gradient Boosting (XGBoost) model and the Shapley Additive exPlanations (SHAP) were deployed for analyzing the importance of 15 agrometeorological variables in predicting oil palm yield. The best model attained 1.911 RMSE and 0.855 R2. By analyzing the weights and gains of the XGBoost model along with the SHAP values, it was found that the yield in the previous year, the age and number of plants, the area of peat lands, and meteorological parameters such as rainfall rates and the number of rainy days in the previous three years were considered important. The previous year's yield in particular possesses the greatest weight and gain values according to the model, and the highest SHAP value among all input variables. However, the meteorological data used in this research are only limited to rainfall rates and the number of rainy days. In the future, more diverse variables can be analyzed.

关键词： Oil Palm Yield Machine Learning XGBoost XAI SHAP

来源：评论

学校读者我要写书评

暂无评论

InDRI: Intelligent Diagnosis Radiology Images

InDRI: Intelligent Diagnosis Radiology Images

引用

International Conference on Cybernetics and Intelligent System (ICORIS)

作者： Mahmud Isnan Gregorius Natanael Elwirehardja Kuncahyo Setyo Nugroho Imelda Liana Ritonga Roby Pahala Januario Gultom Elida Afni Lubis Bens Pardamean Computer Science Department School of Computer Science Bina Nusantara University Jakarta Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Undergraduate of Nursing Program Universitas Imelda Medan Indonesia Medan Indonesia Undergraduate Pharmacy Program Universitas Imelda Medan Indonesia Medan Indonesia Clinical Pathology Unit Rumah Sakit Imelda Pekerja Indonesia Medan Indonesia Computer Science Department BINUS Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9798331539603

ISBN: (纸本)9798331539610

The need for an early screening and Computer-Aided Diagnosis (CAD) system based on Artificial Intelligence (AI) for the field of radiology is essential to realize considering the large impact of lung diseases globally. However, developing AI requires a lot of data, which is a challenge because data in the health sector tends to be limited in quantity and has disparities between diagnostic categories (data imbalance). To overcome this issue, DINO ViT models was trained with the publicly available COVID-19 Radiography Database in our previous study. The model was subsequently implemented into a web application, with this study focusing on the development of a prototype for the application. The study found this application can be useful for medical personnel and doctors in carrying out early screening and CAD. Meanwhile, it also highlighted the general unfamiliarity with AI applications among medical staff, emphasizing the need for increased education and training on AI's role in healthcare.

关键词： Training Solid modeling Design automation Pulmonary diseases Prototypes Radiology Predictive models Computer aided diagnosis Artificial intelligence Medical diagnostic imaging

来源：评论

学校读者我要写书评

暂无评论

Lockdown strategy worth lives: The SEIRD modelling in COVID-19 outbreak in Indonesia 2

Lockdown strategy worth lives: The SEIRD modelling in COVID-...

引用

2nd International Conference on Biospheric Harmony Advanced Research, ICOBAR 2020

作者： Nurlaila, I. Hidayat, A.A. Pardamean, B. Information Systems Department BINUS Online Learning Bina Nusantara University Jakarta11480 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program-Master of Computer Science Bina Nusantara University Jakarta11480 Indonesia

Lockdowns, despite their conflicting restrictions and consequences they might offer when enforced as a national strategy, are deemed to be suggestive for a prompt conquer to the Coronavirus Disease-19 (COVID-19) outbreak. There have been some success stories such as in China, South Korea and our ASEAN member fellow, Vietnam, which exhibited extremely fallen numbers of COVID-19 cases post the enforcement of lockdown. Indonesia, however, remains in the crux of dispute whether or not the lockdown is opted to force COVID-19 transmission down under control. We, in this respect, employ the most popular model which has been broadly applied in the field of epidemiology, referred to as SEIRD (Susceptible, Exposed, Infectious, Recovered, and Death), the extension form of an age-structured SEIR, where the Death (D) is included to provide more factual situation. We modify the I (Infectious) fraction as symp-tomatic (Is) and asymptomatic (Ia) infectives. There are three lockdown scenarios simulated in our modified SEIRD with the starting date are 26 April 2020 when the immediate lockdown was enacted-and a-week and two-week-gaps, respectively. We figured out that by stipulating the lockdown without delay (26 April 2020), the new cases could be kept below 10,000. A week delay escalates case number to 5,000 and delay for one more week results in beyond 20,000 new cases. Furthermore, when the intervention is delayed following the delayed lockdown, normalization would demand a longer period within which dealing with more critical and dying patients is unavoidable and should be more anticipated. © Published under licence by IOP Publishing Ltd.

关键词： Coronavirus

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：