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检索条件"机构=Modeling and Design Program"
81 条 记 录,以下是61-70 订阅
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Do crystal structures obviate the need for theoretical models of GPCRs for structure-based virtual screening?
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PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 2012年 第6期80卷 1503-1521页
作者: Tang, Hao Wang, Xiang Simon Hsieh, Jui-Hua Tropsha, Alexander Howard Univ Coll Pharm Dept Pharmaceut Sci Lab Cheminfomat & Drug Design Washington DC 20059 USA Univ N Carolina Lab Mol Modeling Div Med Chem & Nat Prod Chapel Hill NC 27599 USA Univ N Carolina Sch Pharm Carolina Exploratory Ctr Cheminformat Res Chapel Hill NC 27599 USA Univ N Carolina Sch Med Biophys Program Chapel Hill NC 27599 USA
Recent highly expected structural characterizations of agonist-bound and antagonist-bound beta-2 adrenoreceptor (beta 2AR) by X-ray crystallography have been widely regarded as critical advances to enable more effecti... 详细信息
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A Contribution to Transaction Costs: Evidence From Banana Markets in Ethiopia
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AGRIBUSINESS 2011年 第4期27卷 493-508页
作者: Woldie, Getachew A. Nuppenau, E. A. Ontario Minist Environm Modeling & Anal Grp Toronto ON Canada Univ Giessen Inst Agr Policy & Market Res D-35390 Giessen Germany Ontario Minist Environm Modeling & Anal Sect Air Policy Instruments & Program Design Branch Toronto ON Canada
Banana producers in Ethiopia sell their produce through wholesale traders, cooperatives, and to village retailers and local consumers. Factors determining the selection of marketing channels and their implication on t... 详细信息
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Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain
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RETROVIROLOGY 2011年 第1期8卷 28-28页
作者: Zhang, Hongtao Curreli, Francesca Zhang, Xihui Bhattacharya, Shibani Waheed, Abdul A. Cooper, Alan Cowburn, David Freed, Eric O. Debnath, Asim K. New York Blood Ctr Lindsley F Kimball Res Inst Lab Mol Modeling & Drug Design New York NY 10065 USA New York Struct Biol Ctr New York NY 10027 USA NCI Virus Cell Interact Sect HIV Drug Resistance Program Frederick MD 21702 USA Univ Glasgow Sch Chem Glasgow G12 8QQ Lanark Scotland Yeshiva Univ Albert Einstein Coll Med Bronx NY 10461 USA
Background: The C-terminal domain (CTD) of HIV-1 capsid (CA), like full-length CA, forms dimers in solution and CTD dimerization is a major driving force in Gag assembly and maturation. Mutations of the residues at th... 详细信息
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Inactivated trivalent seasonal influenza vaccine induces limited cross-reactive neutralizing antibody responses against 2009 pandemic and 1934 PR8 H1N1 strains
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VACCINE 2010年 第42期28卷 6852-6857页
作者: Lee, Vernon J. Tay, Joshua K. Chen, Mark I. C. Phoon, M. C. Xie, M. L. Wu, Y. Lee, Cynthia X. X. Yap, Jonathan Sakharkar, K. R. Sakharkar, M. K. Lin, Raymond T. Cui, Lin Kelly, Paul M. Leo, Yee Sin Tan, Yee Joo Chow, Vincent T. K. Singapore Armed Forces Biodef Ctr Singapore 778910 Singapore Australian Natl Univ Natl Ctr Epidemiol & Populat Hlth Canberra ACT 0200 Australia Natl Univ Singapore Yong Loo Lin Sch Med Dept Epidemiol & Publ Hlth Singapore 117597 Singapore Tan Tock Seng Hosp Singapore 308433 Singapore Natl Univ Singapore Yong Loo Lin Sch Med Dept Microbiol Program Infect Dis Singapore 117597 Singapore Nanyang Technol Univ Sch Mech & Aerosp Engn Coll Engn Adv Design & Modeling Lab Singapore 639798 Singapore Nanyang Technol Univ Biomed Engn Res Ctr Singapore 639798 Singapore Minist Hlth Natl Publ Hlth Lab Singapore 169854 Singapore
Background: In June 2009, we conducted a prospective study in Singapore on 51 individuals to determine their serologic responses before and following receipt of the 2009 Southern Hemisphere seasonal influenza vaccine.... 详细信息
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Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008
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NATURE REVIEWS DRUG DISCOVERY 2009年 第6期8卷 455-463页
作者: Michino, Mayako Abola, Enrique Brooks, Charles L., III Dixon, J. Scott Moult, John Stevens, Raymond C. Olson, Arthur Jurkowski, Wiktor Elofsson, Arne Filipek, Slawomir Pogozheva, Irina Lomize, Andrei Maigret, Bernard Horst, Jeremy Bernard, Brady Iyer, Shyamala Samudrala, Ram Roy, Ambrish Zhang, Yang Sezerman, Osman Ugur Nikiforovich, Gregory V. Taylor, Christina M. Costanzi, Stefano Vorobjev, Y. Bakulina, N. Solovyev, V. Kanou, Kazuhiko Takaya, Daisuke Terashi, Genki Takeda-Shitaka, Mayuko Umeyama, Hideaki Goddard, William A., III Li, Youyong Kim, Soo-Kyung Trzaskowski, Bartosz Abrol, Ravinder Griffith, Adam Katritch, Vsevolod Rueda, Manuel Davis, Ian Barth, Patrick Baker, David Feig, Michael Brylinski, Michal Zhou, Hongyi Lee, Seung Yup Skolnick, Jeffrey Ostopovici-Halip, Liliana Bologa, Cristian Lam, Polo Abagyan, Ruben Dawson, Eric S. Kaufmann, Kristian Woetzel, Nils Meiler, Jens Ding, Feng Serohijos, Adrian Yin, Shuangye Dokholyan, Nikolay V. Rodriguez, David Gutierrez-de-Teran, Hugo Xhaard, Henri Scripps Res Inst Dept Mol Biol 10666 N Torrey Pines Rd La Jolla CA 92037 USA Scripps Res Inst Dept Chem La Jolla CA 92037 USA Univ Michigan Dept Chem Ann Arbor MI 48109 USA Univ Michigan Biophys Program Ann Arbor MI 48109 USA Daylight Chem Informat Syst Inc Aliso Viejo CA 92656 USA Univ Maryland Inst Biotechnol Ctr Adv Res Biotechnol Rockville MD 20850 USA Stockholm Univ Ctr Biomembrane Res Dept Biochem & Biophys S-10691 Stockholm Sweden Int Inst Mol & Cell Biol Lab Biomodelling Warsaw Poland Univ Michigan Peptide Synth & Mol Recognit Lab Ann Arbor MI 48109 USA Nancy Univ LORIA Orpailleur Team Nancy France Univ Washington Computat Biol Grp Seattle WA 98195 USA Univ Kansas Dept Mol Biosci Ctr Bioinformat Lawrence KS 66045 USA Sabanci Univ Biol Sci & Bioengn Istanbul Turkey MolLife Design LLC St Louis MO USA Washington Univ Dept Biochem & Mol Biophys St Louis MO 63130 USA NIH Lab Biol Modeling NIDDKD Bethesda MD 20892 USA Univ London Royal Holloway Dept Comp Sci London TW20 0EX England Softberry Inc Mt Kisco NY 10549 USA Kitasato Univ Sch Pharm Tokyo 1088641 Japan RIKEN Syst & Struct Biol Ctr Yokohama Kanagawa 2300045 Japan CALTECH Mat & Proc Simulat Ctr Pasadena CA 91125 USA Molsoft LLC San Diego CA USA Univ Washington Dept Biochem Seattle WA 98195 USA Michigan State Univ Dept Biochem & Mol Biol E Lansing MI 48824 USA Georgia Inst Technol Ctr Study Syst Biol Atlanta GA 30332 USA Univ New Mexico Div Biocomp Albuquerque NM 87131 USA Vanderbilt Univ Ctr Struct Biol Nashville TN 37235 USA Univ N Carolina Dept Biochem & Biophys Chapel Hill NC USA Complejo Hosp Univ Santiago de Compostela Fdn Publ Galega Med Xen Santiago De Compostela Spain Univ Helsinki Fac Pharm Ctr Drug Res FIN-00014 Helsinki Finland
Recent breakthroughs in the determination of the crystal structures of G protein-coupled receptors (GPCRs) have provided new opportunities for structure-based drug design strategies targeting this protein family. With... 详细信息
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Tfe Solberg Award
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Naval Engineers Journal 2009年 第5期112卷
作者: Dr. Roy L. Streit Since 1992 Dr. Streit has focused a significant amount of his energy to assignment problems in acoustic warfare data fusion systems. This work led him to the formulation of the PDD Principle a broadly useful theoretical method that enables the derivation of new classes of discrete-continuous estimation algorithms for solving assignment problems without requiring enumeration and pruning. In recognition of his outstanding work in this area Dr. Streit received the NAVSEA Scientist of the Year Award for 1997. Dr. Streit has also been pursuing avenues for analyzing the loss in broadband detection performance of an acoustic array in the presence of interferences. Because examining all possible separations between the signal and many interferers is infeasible he has proposed a Poisson process model for the number and location (s) of the interferers. In this same time period Dr. Streit has also been investigating issues in environmental modeling and localization by proposing a novel integral method for solving the bearings-only target motion analysis problem which enables a natural heuristic for compensating for mismatch between the model predictions and the real world. Most recently Dr. Streit has proposed the Numerical ACoustic Hull ARray (NACHAR) Project as a revolutionary and ambitious approach to hull array design. Its premise is that optimizing the detection capability of large hull arrays requires the full integration of hull sensor array and beamformer design processes. Because NACHAR crosses an unusual number of technical disciplines it involves researchers from several departments. The diversity of Dr. Streif s technical background makes him uniquely suited to lead the project Dr. Streifs truly impressive scientific achievements are complemented by a noteworthy list of professional activities that accentuate his value to Division Newport and the Navy. He represents the United States in The Technical Cooperation Program Maritime Activities Panel 9 (Sonar Technology) and participates in the Division New
for his significant engineering research and development in sonar array research and acoustic transient signals as set forth in the following
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Redesigning a college-wide multidisciplinary engineering design program at RIT
Redesigning a college-wide multidisciplinary engineering des...
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114th Annual ASEE Conference and Exposition, 2007
作者: Walter, Wayne Webb, Jeffrey Smith, Mark DeBartolo, Elizabeth Bailey, Margaret Slack, George Rochester Institute of Technology United States Department of Mechanical Engineering RIT United States Engineering Modeling and Simulations Group Southeast Division of Applied Research Associates Programs Rochester Institute of Technology United States United States Engineering Honors Program United States Multidisciplinary Capstone Design Leadership Team United States Senior Design and Digital Systems United States Xerox Corp Bosch Corp. United States
Since 2002, the Kate Gleason College of Engineering (KGCOE) at the Rochester Institute of Technology (RIT) has seen its Multidisciplinary Senior design (MSD) program grow from a small pilot project into a college-wide... 详细信息
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MARKOV DECISION PROCESSES WITH UNCERTAIN TRANSITION RATES: SENSITIVITY AND MAX HYPHEN MIN CONTROL
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Asian Journal of Control 2008年 第2期6卷
作者: Suresh Kalyanasundaram Edwin K. P. Chong Ness B. Shroff Motorola India Electronics Limited No. 66/1 Plot 5 Bagmane Techpark C. V. Raman Nagar Post Bangalore 560 093 India. Department of Electrical and Computer Engineering Colorado State University Fort Collins CO 80523-1373 USA. Professor Edwin K. P. Chong received the B.E.(Hons.) degree with First Class Honors from the University of Adelaide South Australia in 1987 graduating top of his class and the M.A. and Ph.D. degrees in 1989 and 1991 respectively both from Princeton University where he held an IBM Fellowship. He joined the School of Electrical and Computer Engineering at Purdue University in 1991 where he was named a University Faculty Scholar in 1999 and promoted to Full Professor in 2001. Since August 2001 he has been a Professor of Electrical and Computer Engineering and Professor of Mathematics at Colorado State University. His current interests are in communication networks and optimization methods. He coauthored the best-selling book An Introduction to Optimization 2nd Edition Wiley-Interscience 2001. He received the NSF CAREER Award in 1995 and the ASEE Frederick Emmons Terman Award in 1998. He coauthored a paper that was awarded Best Paper in the journal Computer Networks 2003. Professor Chong is a Fellow of the IEEE. He was founding chairman of the IEEE Control Systems Society Technical Committee on Discrete Event Systems and until recently served as an IEEE Control Systems Society Distinguished Lecturer. He has been on the editorial board of the IEEE Transactions on Automatic Control. He is currently on the editorial board of the journal Computer Networks. He has also served on the organizing committees of several international conferences. He has been on the program committees for the IEEE Conference on Decision and Control the American Control Conference the IEEE International Symposium on Intelligent Control IEEE Symposium on Computers and Communications and the IEEE Global Telecommunications Conference. He has also served in the executive committees for the IEEE Co
Solution techniques for Markov decision problems rely on exact knowledge of the transition rates, which may be difficult or impossible to obtain. In this paper, we consider Markov decision problems with uncertain tran... 详细信息
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Beyond the AFCEE protocol for natural attenuation
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GROUND WATER MONITORING AND REMEDIATION 1998年 第3期18卷 70-77页
作者: Nyer, EK Mayfield, P Hughes, J Evan K. Nyer is a vice president with ARCADIS Geraghty & Miller Inc. where he is responsible for maintaining and expanding the company's technical expertise in geology/hydrogeology engineering modeling risk assessment and bioremediation. He has been active in the development of new treatment technologies for many years. His areas of research interest include biological treatment suspended solids separation chemical oxidation in situ treatment air treatment systems and the application of new technologies to ground water cleanup. He has been responsible for the strategies technical design and installation of more than 200 ground water and soil remediation systems at contaminated sites throughout the United States. Paulette Mayfield is the project manager for engineering services in ARCADIS Geraghty & Miller Inc. 's Austin Texas office. As such she manages engineering projects conducted by the office and also provides engineering and regulatory support for projects conducted by ARCADIS Geraghty & Miller nationwide. She is also a member of ARCADIS Geraghty & Miller's compliance audit team and has participated in or managed numerous projects associated with RCRA program compliance solid and hazardous waste management regulatory analysis and compliance planning and facility closure/demolition/ property redevelopment. She has participated in the design operation management and evaluation of numerous bioremediation projects including hazardous waste land treatment units petroleumcontaminated soil remediation projects and ground water natural attenuation and enhanced natural attenuation projects. Mayfield also conducted two years of laboratory research involving the in situ biodegradation of petroleum products. She received her graduate degree in environmental engineering from Texas Tech University and has co-authored several publications addressing in situ bioremediation techniques. Joseph D. Hughes is a hydrogeologist in ARCADIS Geraghty & Miller's Tampa Florida office. His areas of research int
The historical analytical data collected at Murdock demonstrate that: Constitutent concentrations in ground water in the area of highest known contaminant concentrations and along the flow path downgradient of that ar...
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Identifying synergy between remedial strategies and land reuse
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GROUND WATER MONITORING AND REMEDIATION 1998年 第4期18卷 61-65页
作者: Nyer, EK Graves, LS Evan K. Nyer is a vice president with ARCADIS Geraghty & Miller Inc. where he is responsible for maintaining and expanding the company's technical expertise in geology/hydrogeology engineering modeling risk assessment and bioremediation. He has been active in the development of new treatment technologies for many years. His areas of research interest include biological treatment suspended solids separation chemical oxidation in situ treatment air treatment systems and the application of new technologies to ground water cleanup. He has been responsible for the strategies technical design and installation of more than 200 ground water and soil remediation systems at contaminated sites throughout the United States. Lawrence S. Graves CPG CP is president and owner of L.S. Graves Associates Inc. specializing in environment and land reuse consulting services. He has 20 years experience in the environmental field serving in a variety of technical and management roles. During the past 10 years he has focused on the issues surrounding reuse of industrial and commercial property having environmental concerns. He is an expert in the identification of site conditions remedial alternatives and land uses that are synergistic. He is a certified professional under the Ohio Voluntary Action Program and a certified professional geologist with the American Institute of Professional Geologists. He holds an M.S. degree in geology with emphasis in environmental and hydrogeology from Bowling Green State University.
“Today the environmental professional teams with the developer to use remedial technologies and approaches that complement planned land use and, conversely, use land in a fashion that accommodates environmental site ...
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