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检索条件"机构=Molecular Regulation and Bioinformatics Laboratory"
42 条 记 录,以下是1-10 订阅
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Clonal hematopoiesis landscape in frequent blood donors
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Blood 2025年 第21期145卷 2411-2423页
作者: Karpova, Darja Huerga Encabo, Hector Donato, Elisa Calderazzo, Silvia Scherer, Michael Llorian-Sopena, Miriam Leppä, Aino-Maija Würth, Roberto Stelmach, Patrick Papazoglou, Despoina Ferrelli, Alessandra Ngo, Steven Kotova, Iuliia Harenkamp, Sabine Zimmer, Kai Wolf, Dominik Panten, Jasper Reed, John Przybylla, Adriana Tonn, Torsten Kopp-Schneider, Annette Velten, Lars DiPersio, John F. Wong, Terrence N. Bonnet, Dominique Bonig, Halvard Trumpp, Andreas Division of Stem Cells and Cancer German Cancer Research Center Heidelberg Germany Heidelberg Institute for Stem Cell Technology and Experimental Medicine Heidelberg Germany German Cancer Consortium Heidelberg Germany Division of Oncology Department of Medicine Washington University School of Medicine St. Louis MO Institute for Transfusion Medicine and Immunohematology Goethe University Hospital Medical School German Red Cross Blood Donor Service Frankfurt Germany Hematopoietic Stem Cell Laboratory The Francis Crick Institute London United Kingdom Division of Biostatistics German Cancer Research Center Heidelberg Germany Computational Biology and Health Genomics Centre for Genomic Regulation Barcelona Institute of Science and Technology Barcelona Spain Division of Cancer Epigenomics German Cancer Research Centre Heidelberg Germany Bioinformatics and Biostatistics The Francis Crick Institute London United Kingdom European Molecular Biology Laboratory Hamburg Germany Department of Internal Medicine V Hematology and Oncology Comprehensive Cancer Center Innsbruck Medical University of Innsbruck Innsbruck Austria VASCage–Centre on Clinical Stroke Research Innsbruck Austria Division of Regulatory Genomics and Cancer Evolution German Cancer Research Center Heidelberg Germany Division of Cancer Biology Department of Medicine University of Michigan Medical School Ann Arbor MI United States
Donor blood saves lives, yet the potential impact of recurrent large-volume phlebotomy on donor health and hematopoietic stem cells (HSCs) remains largely unexplored. In our study, we conducted a comprehensive screeni...
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Deletion of a single CTCF motif at the boundary of a chromatin domain with three FGF genes disrupts gene expression and embryonic development
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Developmental Cell 2025年
作者: Chakraborty, Shreeta Wenzlitschke, Nina Anderson, Matthew J. Eraso, Ariel Baudic, Manon Thompson, Joyce J. Evans, Alicia A. Shatford-Adams, Lilly M. Chari, Raj Awasthi, Parirokh Dale, Ryan K. Lewandoski, Mark Petros, Timothy J. Rocha, Pedro P. Unit on Genome Structure and Regulation National Institute of Child Health and Human Development National Institutes of Health Bethesda 20892 MD United States Genetics of Vertebrate Development Section Cancer and Developmental Biology Laboratory National Cancer Institute National Institutes of Health Frederick 21702 MD United States Bioinformatics and Scientific Programming Core National Institute of Child Health and Human Development National Institutes of Health Bethesda 20892 MD United States Laboratory Animal Sciences Program Frederick National Laboratory for Cancer Research Frederick 21702 MD United States Unit on Cellular and Molecular Neurodevelopment National Institute of Child Health and Human Development National Institutes of Health Bethesda 20892 MD United States National Cancer Institute NIH Bethesda 20892 MD United States
Chromatin domains delimited by CTCF can restrict the range of enhancer action. However, disruption of some domain boundaries results in mild gene dysregulation and phenotypes. We tested whether perturbing a domain wit... 详细信息
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A multi-disciplinary approach to study the biological role of miRNA in deep-branching unicellular flagellates
A multi-disciplinary approach to study the biological role o...
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2011国际基因组学大会
作者: Petrus Tang Po-Jung Huang Shih-Chieh Chen Bioinformatics Center Chang Gung UniversityTaoyuanTaiwan Molecular Regulation&Bioinformatics Laboratory Dept.of ParasitologyChang Gung UniversityTaiwan Molecular Regulation & Bioinformatics Laboratory Dept.of ParasitologyChang Gung UniversityTaiwan
MicroRNAs(miRNAs) are a class of extensively studied small RNA population that plays a critical role in eukaryotic gene ***,very little is known about the regulation of miRNA in *** explore the evolutionary origins of... 详细信息
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A multi-disciplinary approach to study the biological role of miRNA in deep-branching unicellular flagellates
A multi-disciplinary approach to study the biological role o...
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2011·国际基因组学大会
作者: Petrus Tang Po-Jung Huang Wei-Chen Lin Shih-Chieh Chen Yong-Han Lin Bioinformatics Center Chang Gung University Taoyuan Taiwan Molecular Regulation & Bioinformatics Laboratory Dept.of Parasitology Chang Gung University Taiwan Bioinformatics Center Chang Gung University Taoyuan Taiwan Molecular Regulation & Bioinformatics Laboratory Dept.of Parasitology Chang Gung University Taiwan
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Exploring the sequence determinants of amyloid structure using position-specific scoring matrices (vol 7, pg 237, 2010)
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NATURE METHODS 2010年 第10期7卷 855-855页
作者: Maurer-Stroh, Sebastian Debulpaep, Maja Kuemmerer, Nico de la Paz, Manuela Lopez Martins, Ivo Cristiano Reumers, Joke Morris, Kyle L. Copland, Alastair Serpell, Louise Serrano, Luis Schymkowitz, Joost W. H. Rousseau, Frederic VIB SWITCH Laboratory Flanders Institute for Biotechnology and Vrije Universiteit Brussel Brussels Belgium. Bioinformatics Institute (BII) Agency for Science Technology and Research (ASTAR) Singapore. Structures Programme European Molecular Biology Laboratory Heidelberg Germany. Department of Chemistry School of Life Sciences University of Sussex Falmer Brighton UK. Systems Biology Programme Centre for Genomic Regulation Barcelona Spain.
Protein aggregation results in β-sheet–like assemblies that adopt either a variety of amorphous morphologies or ordered amyloid-like structures. These differences in structure also reflect biol... 详细信息
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Pilot Survey of Expressed Sequence Tags (EST) from Trichomonas vaginalis
Pilot Survey of Expressed Sequence Tags (EST) from Trichomon...
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12th International Congress of Protozoology
作者: Petrus Tang ChengHsun Chiu JyhWei Shin Rose Lin Weimin Hsu Sara Yu-Hsin Cheng Chun-Hsien Chen Ying-Shiung Lee Molecular Regulation and Bioinformatics Laboratory Department of Parasitology Chang Gung University Taoyuan 333 Taiwan Chang Gung Bioinformatics Center Taoyuan 333 Taiwan Chang Gung Molecular Infectious Diseases Research Center Chang Gung Memorial Hospital Taoyuan 333 Taiwan Department of Parasitology Medical College National Cheng Kung University No. 1 Dashiue Road 701 Dung Chiu Tainan Taiwan Molecular Regulation and Bioinformatics Laboratory Department of Parasitology Chang Gung University Taoyuan 333 Taiwan Molecular Regulation and Bioinformatics Laboratory Department of Parasitology Chang Gung University Taoyuan 333 Taiwan Chang Gung Bioinformatics Center Taoyuan 333 Taiwan Department of Information Management College of Management Chang Gung University Taoyuan 333 Taiwan Medical Genomic Center Chang Gung Memorial Hospital Taoyuan 333 Taiwan
A Trichomonas vaginalis expressed sequence tag (TvEST) project is being carried out to generate and analysis 60,000 ESTs. A pilot survey was conducted on 26,571 randomly selected EST clones from normal, cold-stressed ... 详细信息
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Epitranscriptomic technologies and analyses
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Science China(Life Sciences) 2020年 第4期63卷 501-515页
作者: Xiaoyu Li Qiao-Xia Liang Jin-Ran Lin Jinying Peng Jian-Hua Yang Chengqi Yi Yang Yu Qiangfeng Cliff Zhang Ke-Ren Zhou State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China MOE Key Laboratory of Gene Function and Regulation State Key Laboratory for BiocontrolSchool of Life SciencesSun Yat-Sen UniversityGuangzhou 510275China The Fifth Affiliated Hospital Sun Yat-Sen UniversityZhuhai 519000China Department of Chemical Biology and Synthetic and Functional Biomolecules Center College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China Key Laboratory of RNA Biology CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101 China MOE Key Laboratory of Bioinformatics Beijing Advanced Innovation Center for Structural BiologyCenter for Synthetic and Systems BiologyTsinghua-Peking Joint Center for Life SciencesSchool of Life SciencesTsinghua UniversityBeijing 100084China
RNA can interact with RNA-binding proteins(RBPs),mRNA,or other non-coding RNAs(ncRNAs)to form complex regulatory ***-throughput CLIP-seq,degradome-seq,and RNA-RNA interactome sequencing methods represent powerful appr... 详细信息
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Identification of microRNA in the protist Trichomonas vaginalis
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Genomics 2009年 第5期93卷 487-493页
作者: Lin, Wei-Chen Li, Sung-Chou Lin, Wen-Chang Shin, Jyh-Wei Hu, Song-Nian Yu, Xiao-Min Huang, Ting-Yun Chen, Shih-Chieh Chen, Hua-Chien Chen, Shu-Jen Huang, Po-Jung Ruei-Chi Gan, Richie Chiu, Cheng-Hsun Tang, Petrus Molecular Regulation and Bioinformatics Laboratory Chang Gung University Taoyuan 333 Taiwan Division of Microbiology Graduate Institute of Biomedical Sciences Chang Gung University Taoyuan 333 Taiwan Institute of Biomedical Informatics National Yang-Ming University Taipei 112 Taiwan Taiwan International Graduate Program in Bioinformatics Academia Sinica Taipei 115 Taiwan Institute of Biomedical Sciences Academia Sinica Taipei 115 Taiwan Department of Parasitology National Cheng Kung University Tainan 701 Taiwan Key Laboratory of Genome Sciences and Information Beijing Institute of Genomics Chinese Academy of Sciences Beijing China Graduate University Chinese Academy of Sciences Beijing China Department of Life Sciences Chang Gung University Taoyuan 333 Taiwan Molecular Medicine Research Center Chang Gung University Taoyuan 333 Taiwan Bioinformatics Center Chang Gung University Tao-Yuan 333 Taiwan Chang Gung Molecular Infectious Diseases Research Center Chang Gung Memorial Hospital Taoyuan 333 Taiwan
MicroRNAs (miRNAs) are a class of small noncoding RNAs that have important regulatory roles in multicellular organisms. However, miRNA has never been identified experimentally in protist. Direct cloning of 438 express... 详细信息
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0414 Recurrent chimeric transcripts in human and mouseGet access
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Journal of Animal Science 2016年 第SUPPL_5期94卷 200–201页
作者: Djebali, S. Rodríguez Martín, B. Palumbo, E. Pervouchine, D. D. Breschi, A. Davis, C. Dobin, A. Alonso, G. Rastrojo, A. Aguado, B. Gingeras, T. R. Guigó, R. GenPhySE INRA Castanet-Tolosan France Universitat Pompeu Fabra (UPF) Barcelona Spain Bioinformatics and Genomics Program Centre for Genomic Regulation (CRG) Barcelona Spain Cold Spring Harbor Laboratory Functional Genomics NY Centro de Biología Molecular Severo Ochoa (CSIC- UAM) Madrid Spain
The formation of chimeric transcripts (chimeras) has been widely reported. Some of them reflect underlying chromosomal rearrangements, or are the results of the propensity of reverse transcriptase to engage in templat... 详细信息
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Image Data Resource: a bioimage data integration and publication platform (vol 14, pg 775, 2017)
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NATURE METHODS 2018年 第11期15卷 984-984页
作者: Williams, Eleanor Moore, Josh Li, Simon W. Rustici, Gabriella Tarkowska, Aleksandra Chessel, Anatole Leo, Simone Antal, Balint Ferguson, Richard K. Sarkans, Ugis Brazma, Alvis Salas, Rafael E. Carazo Swedlow, Jason R. Centre for Gene Regulation and Expression University of Dundee Dundee UK Division of Computational Biology University of Dundee Dundee UK European Molecular Biology Laboratory European Bioinformatics Institute Hinxton UK Pharmacology Department University of Cambridge Cambridge UK Genetics Department University of Cambridge Cambridge UK Cambridge Systems Biology Centre University of Cambridge Cambridge UK LOB Ecole Polytechnique CNRS INSERM Université Paris-Saclay Palaiseau France Center for Advanced Studies Research and Development in Sardinia (CRS4) Pula Italy School of Cell and Molecular Medicine University of Bristol Bristol UK
This paper was originally published under standard Nature America Inc. copyright. As of the date of this correction, the Resource is available online as an open-access paper with a CC-BY license. No other part of the ...
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