Retinal diseases including age-related macular degeneration and diabetic retinopathy are leading causes of visual impairment and a growing medical crisis worldwide. As a result, new therapies and methods of safely del...
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Retinal diseases including age-related macular degeneration and diabetic retinopathy are leading causes of visual impairment and a growing medical crisis worldwide. As a result, new therapies and methods of safely delivering these new therapies can be of significant benefit to society. In this paper, we present a proof-of-concept for performing drug delivery using flexible magnetic microcatheters. The potential benefits of these catheters are that they are safer to use than existing rigid vitreoretinal tools, are precisely manipulable, and can be used to deliver lower dosages of therapeutic agents to precisely targeted locations on the retina with higher efficacy. The task of positioning the catheter tip is shared between a human operator and a control algorithm, which have complementary skills and can separately address different aspects of the overall task. The system was tested in an eye-phantom by an untrained operator with a 93% success rate in reaching 43 target points uniformly dispersed over the retina.
This paper presents the design of the Interacting-BoomCopter (I-BoomCopter) unmanned aerial vehicle (UAV), designed specifically for environmental interactions. The novel design consists of a horizontally mounted four...
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This paper presents the design of the Interacting-BoomCopter (I-BoomCopter) unmanned aerial vehicle (UAV), designed specifically for environmental interactions. The novel design consists of a horizontally mounted four-blade reversible propeller on a front boom that is attached to a standard tri-rotor UAV configuration. A custom end-effector and force sensor is placed at the end of the front boom for autonomous pushing and pulling interaction tasks. The modeling of the new platform is presented and two prototype versions built, flight tested, and characterized. Finally, the efficacy of the new platform for environmental interactions is evaluated with an autonomous door opening task and a teleoperated door opening and door closing task.
Background: Cataracts are the leading cause of blindness and are treated surgically. Capsulotomy describes the opening of the lens capsule during this surgery and is most commonly performed by manual tearing, thermal ...
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Summary Intravitreal therapy is the most common treatment for many ophthalmic diseases, such as age-related macular degeneration or diabetic retinopathy. To render this procedure time and cost efficient, as well as to...
Summary Intravitreal therapy is the most common treatment for many ophthalmic diseases, such as age-related macular degeneration or diabetic retinopathy. To render this procedure time and cost efficient, as well as to increase patient safety, an automated assistive device for intravitreal injections has been designed and is introduced in this talk. The system allows for precise and safe injections through the pars plana but is still controlled and monitored by the treating physician.
Summary Efficient ocular surgery must be precise, safe and cost effective. Minimally invasive microrobots for ophthalmic applications have been introduced for high precision motion with force feedback. Research demons...
Summary Efficient ocular surgery must be precise, safe and cost effective. Minimally invasive microrobots for ophthalmic applications have been introduced for high precision motion with force feedback. Research demonstrates the potential of wireless magnetic microrobots for targeted drug delivery to the retina and operations in the posterior eye segment without the need for a vitrectomy.
Understanding the mechanisms of plant growth and morphogenesis is of importance, not only to the field of plant sciences but also in a broader agricultural and economical context, as plants provide important raw mater...
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