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arXiv 2023年

作者： Tian, Chunwei Zhang, Xuanyu Zhang, Qi Yang, Mingming Ju, Zhaojie School of Software Northwestern Polytechnical University Xi’an710129 China National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology Xi’an710129 China Research & Development Institute Northwestern Polytechnical University Shenzhen China School of Economics and Management Harbin Institute of Technology at Weihai Weihai264209 China Tencent AI lab Shenzhen China School of Computing University of Portsmouth PortsmouthPO1 3HE United Kingdom

Convolutional neural networks depend on deep network architectures to extract accurate information for image super-resolution. However, obtained information of these convolutional neural networks cannot completely express predicted high-quality images for complex scenes. In this paper, we present a dynamic network for image super-resolution (DSRNet), which contains a residual enhancement block, wide enhancement block, feature refinement block and construction block. The residual enhancement block is composed of a residual enhanced architecture to facilitate hierarchical features for image super-resolution. To enhance robustness of obtained super-resolution model for complex scenes, a wide enhancement block achieves a dynamic architecture to learn more robust information to enhance applicability of an obtained super-resolution model for varying scenes. To prevent interference of components in a wide enhancement block, a refinement block utilizes a stacked architecture to accurately learn obtained features. Also, a residual learning operation is embedded in the refinement block to prevent long-term dependency problem. Finally, a construction block is responsible for reconstructing high-quality images. Designed heterogeneous architecture can not only facilitate richer structural information, but also be lightweight, which is suitable for mobile digital devices. Experimental results show that our method is more competitive in terms of performance, recovering time of image super-resolution and complexity. The code of DSRNet can be obtained at https://***/hellloxiaotian/DSRNet. Copyright © 2023, The Authors. All rights reserved.

关键词： Network architecture

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Model-assisted inference for covariate-specific treatment effects with high-dimensional data

arXiv

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arXiv 2021年

作者： Wu, Peng Tan, Zhiqiang Hu, Wenjie Zhou, Xiao-Hua Beijing International Center for Mathematical Research Peking University Beijing100871 China Department of Statistics Rutgers University 110 Frelinghuysen Road PiscatawayNJ08854 United States Department of Probability and Statistics Peking University Beijing100871 China Department of Biostatistics Beijing International Center for Mathematical Research National Engineering Laboratory of Big Data Analysis and Applied Technology Peking University Beijing100871 China

Covariate-specific treatment effects (CSTEs) represent heterogeneous treatment effects across subpopulations defined by certain selected covariates. In this article, we consider marginal structural models where CSTEs are linearly represented using a set of basis functions of the selected covariates. We develop a new approach in high-dimensional settings to obtain not only doubly robust point estimators of CSTEs, but also model-assisted confidence intervals, which are valid when a propensity score model is correctly specified but an outcome regression model may be misspecified. With a linear outcome model and subpopulations defined by discrete covariates, both point estimators and confidence intervals are doubly robust for CSTEs. In contrast, confidence intervals from existing high-dimensional methods are valid only when both the propensity score and outcome models are correctly specified. We establish asymptotic properties of the proposed point estimators and the associated confidence intervals. We present simulation studies and empirical applications which demonstrate the advantages of the proposed method compared with competing ones. Copyright © 2021, The Authors. All rights reserved.

关键词： Clustering algorithms

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HNF-Netv2 for Brain Tumor Segmentation using multi-modal MR Imaging

arXiv

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arXiv 2022年

作者： Jia, Haozhe Bai, Chao Cai, Weidong Huang, Heng Xia, Yong Research & Development Institute Northwestern Polytechnical University in Shenzhen Shenzhen518057 China National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology School of Computer Science and Engineering Northwestern Polytechnical University Xi'An710072 China School of Computer Science University of Sydney SydneyNSW2006 Australia Department of Electrical and Computer Engineering University of Pittsburgh PittsburghPA15261 United States JD Finance America Corporation California CA94043 United States

In our previous work, i.e., HNF-Net, high-resolution feature representation and light-weight non-local self-attention mechanism are exploited for brain tumor segmentation using multi-modal MR imaging. In this paper, we extend our HNF-Net to HNF-Netv2 by adding inter-scale and intra-scale semantic discrimination enhancing blocks to further exploit global semantic discrimination for the obtained high-resolution features. We trained and evaluated our HNF-Netv2 on the multi-modal Brain Tumor Segmentation Challenge (BraTS) 2021 dataset. The result on the test set shows that our HNF-Netv2 achieved the average Dice scores of 0.878514, 0.872985, and 0.924919, as well as the Hausdorff distances (95%) of 8.9184, 16.2530, and 4.4895 for the enhancing tumor, tumor core, and whole tumor, respectively. Our method won the RSNA 2021 Brain Tumor AI Challenge Prize (Segmentation Task), which ranks 8th out of all 1250 submitted results. Copyright © 2022, The Authors. All rights reserved.

关键词： Tumors

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H2NF-Net for Brain Tumor Segmentation using Multimodal MR Imaging: 2nd Place Solution to BraTS Challenge 2020 Segmentation Task

arXiv

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arXiv 2020年

作者： Jia, Haozhe Cai, Weidong Huang, Heng Xia, Yong Research & Development Institute Northwestern Polytechnical University in Shenzhen Shenzhen518057 China National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology School of Computer Science and Engineering Northwestern Polytechnical University Xi’an710072 China School of Computer Science University of Sydney SydneyNSW2006 Australia Department of Electrical and Computer Engineering University of Pittsburgh PittsburghPA15261 United States JD Finance America Corporation CaliforniaCA94043 United States

In this paper, we propose a Hybrid High-resolution and Non-local Feature Network (H2NF-Net) to segment brain tumor in multimodal MR images. Our H2NF-Net uses the single and cascaded HNF-Nets to segment different brain tumor sub-regions and combines the predictions together as the final segmentation. We trained and evaluated our model on the Multimodal Brain Tumor Segmentation Challenge (BraTS) 2020 dataset. The results on the test set show that the combination of the single and cascaded models achieved average Dice scores of 0.78751, 0.91290, and 0.85461, as well as Hausdorff distances (95%) of 26.57525, 4.18426, and 4.97162 for the enhancing tumor, whole tumor, and tumor core, respectively. Our method won the second place in the BraTS 2020 challenge segmentation task out of nearly 80 participants. © 2020, CC BY.

关键词： Tumors

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Novel Hemorrhagic Risk Score in Elderly Patients with Coronary Artery Disease and Gastrointestinal Malignant Tumor Comorbidity:A 10-year Clinical Inpatient data analysis from 2 Medical Centers

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Cardiology Discovery 2021年第3期1卷 163-172页

作者： Nandi Bao Wanling Wang Huitao Wu Yabin Wang Hebin Che Wenwen Meng Jiaxin Miao Dong Han Fan Yin National Clinical Research Center for Geriatric Diseases The Second Medical Center of Chinese People's Liberation Army General HospitalBeijing 100853China Medical School of Chinese People's Liberation Army General Hospital Beijing 100853China National Engineering Laboratory for Medical Big Data Application Technology The First Medical Center of Chinese People's Liberation Army General HospitalBeijing 100853China Department of Oncology The Second Medical Center of Chinese People's Liberation Army General HospitalBeijing 100853China

Objective:Older patients with comorbidity,such as coronary heart disease(CHD)and malignant gastrointestinal tumors,are at a high risk of bleeding ***,risk prediction models based on risk factor assessment remain *** study aimed to establish an individualized bleeding risk assessment system based on the analysis of 10-year inpatient clinical big ***:Total clinical data of 56,819 patients with CHD and 25,988 patients with malignant digestive tract tumors(admitted from January 2008 to December 2017)were retrospectively collected at the First and Second Medical Centers of Chinese People's Liberation Army General *** them,1307 patients with CHD and malignant digestive tract tumors were screened as the derivation *** dependent variable was the occurrence of major clinical bleeding *** statistics and hypothesis tests of differences were performed for independent variables according to the occurrence of *** Tree,eXtreme Gradient Boosting(XGBoost),logistic regression,and random forest models were used for *** accuracy,sensitivity,specificity,and area under the receiver operating characteristic curve(AUC-ROC)were applied as the criteria for evaluating and verifying model *** evaluate this developed model,another cohort comprising 454 patients(admitted from January 2018 to December 2019)was prospectively enrolled as the validation cohort based on the same inclusion and exclusion ***:Among the 64 variables with<50%missing values,the recursive feature elimination method with a random forest model was used to screen the selected *** highest accuracy was obtained following the selection of 10 scalars,and the final model was constructed *** demonstrated the best performance *** AUC-ROC of this model was 0.981,with an accuracy,sensitivity,and specificity of 0.939,0.950,and 0.927,*** the validation cohort,the AUC-ROC,accurac

关键词： Coronary disease Gastrointestinal cancers Bleeding Multivariate analysis Risk factors Machine learning

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Reconstructing Missing Modalities in Multi-Modal Endoscopic Ultrasound Via Cross-Modal Feature Replacement Representation

SSRN

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SSRN 2024年

作者： Zheng, Cenyang Gong, Xun Fan, Lin Li, Jiao School of Computing and Artificial Intelligence Southwest Jiaotong University Sichuan Chengdu611756 China Engineering Research Center of Sustainable Urban Intelligent Transportation Ministry of Education Chengdu611756 China National Engineering Laboratory of Integrated Transportation Big Data Application Technology Southwest Jiaotong University Chengdu611756 China Manufacturing Industry Chains Collaboration and Information Support Technology Key Laboratory of Sichuan Province Southwest Jiaotong University Chengdu611756 China Department of Gastroenterology The Third People’s Hospital of Chendu Affiliated Hospital of Southwest Jiaotong University Chengdu610031 China

Endoscopic ultrasound (EUS) is the primary diagnostic imaging technique for gastrointestinal stromal tumors. However, accurately identifying these tumors through EUS imaging alone remains challenging, even for experienced clinicians. They often rely on additional data, such as white light endoscopy (WLE) and EUS text reports, to aid in the diagnosis. Unfortunately, in practice, these supplementary modalities are sometimes overlooked during patient evaluation. To address these issues, we propose the Cross-modal Feature Reconstruction Network (CFRN), which integrates multimodal data modeling for medical diagnostic processes and performs specific learning for different modalities with missing data. The network fuses the multi-modal features based on the clinical medical process, realizes the feature-level missing modality reconstruction, and learns the refined features of different modal true cases by decoding the mode-specific missing. We trained and tested the model on two publicly available datasets, Audiovision-MNIST, MM-IMDb, and data sets collected from real clinical scenarios at three hospitals. Our results show that CFRN outperforms state-of-the-art methods, achieving higher prediction accuracy than using EUS alone. By simultaneously incorporating multimodal or reconstructed modal data for disease diagnosis, our single-modal EUS model proves to be more suitable for clinical scenarios. © 2024, The Authors. All rights reserved.

关键词： Endoscopy

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Hierarchical Attention Feature Fusion and Refinement Network for Point Cloud Upsampling

Hierarchical Attention Feature Fusion and Refinement Network...

引用

IEEE International Conference on Multimedia and Expo (ICME)

作者： Yaori Zhang Shujin Lin Fan Zhou Ruomei Wang National Engineering Research Center of Digital Life School of Computer Science and Engineering Guangdong Provincial Science and Technology Collaborative Innovation Center for Culture and Tourism Sun Yat-sen University Guangzhou China School of Communication and Design Guangdong Key Laboratory for Big Data Analysis and Simulation of Public Opinion Guangdong Provincial Science and Technology Collaborative Innovation Center for Culture and Tourism Sun Yat-sen University Guangzhou China Guangdong Provincial Science and Technology Collaborative Innovation Center for Culture and Tourism National Engineering Research Center of Digital Life School of Computer Science and Engineering Sun Yat-sen University Guangzhou China National Engineering Research Center of Digital Life School of Computer Science and Engineering Sun Yat-sen University Guangzhou China

ISBN: (数字)9798350390155

ISBN: (纸本)9798350390162

This paper presents a novel hierarchical attention feature fusion and refinement network designed to address challenges in existing deep learning based point cloud upsampling methods. The network combines self-attention layers with a multi-level feature extraction architecture, effectively integrating local and global features, thereby enhancing the robustness and uniformity of the point cloud. Furthermore, a spatial refinement module is employed to predict the offset between the generated coarse dense point clouds and real point clouds, thereby enhancing consistency with the ground truth. Concurrently, a filter function is applied in the loss function to handle outliers of generated point clouds. Extensive experimental results across multiple datasets indicate that our method outperforms existing approaches.

关键词： Point cloud compression Deep learning Feature extraction Robustness Encoding

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Adaptive Convolutional Neural Network for Image Super-resolution

arXiv

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arXiv 2024年

作者： Tian, Chunwei Zhang, Xuanyu Wang, Tao Zhang, Yongjun Zhu, Qi Lin, Chia-Wen The School of Software Northwestern Polytechnical University Xi’an710129 China The National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology Xi’an710129 China The Yangtze River Delta Research Institute Northwestern Polytechnical University Taicang215400 China The School of Computer Science Northwestern Polytechnical University Xi’an710129 China The College of Computer Science and Technology Guizhou University Guiyang550025 China The School of Artificial Intelligence Nanjing University of Aeronautics and Astronautics Nanjing210016 China The Department of Electrical Engineering The Institute of Communications Engineering National Tsing Hua University Taiwan

Convolutional neural networks can automatically learn features via deep network architectures and given input samples. However, the robustness of obtained models may face challenges in varying scenes. bigger differences in network architecture are beneficial to extract more diversified structural information to strengthen the robustness of an obtained superresolution model. In this paper, we proposed a adaptive convolutional neural network for image super-resolution (ADSRNet). To capture more information, ADSRNet is implemented by a heterogeneous parallel network. The upper network can enhance relation of context information, salient information relation of a kernel mapping and relations of shallow and deep layers to improve performance of image super-resolution. That can strengthen adaptability of an obtained super-resolution model for different scenes. The lower network utilizes a symmetric architecture to enhance relations of different layers to mine more structural information, which is complementary with a upper network for image super-resolution. The relevant experimental results show that the proposed ADSRNet is effective to deal with image resolving. Codes are obtained at https://***/hellloxiaotian/ADSRNet. Copyright © 2024, The Authors. All rights reserved.

关键词： Convolutional neural networks

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PSGR: Pixel-wise sparse graph reasoning for COVID-19 pneumonia segmentation in CT images

arXiv

引用

arXiv 2021年

作者： Jia, Haozhe Tang, Haoteng Ma, Guixiang Cai, Weidong Huang, Heng Zhan, Liang Xia, Yong National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology School of Computer Science and Engineering Northwestern Polytechnical University Xi’an710072 China Intel Labs 2111 NE 25th Ave HillsboroOR97124 United States School of Computer Science University of Sydney SydneyNSW2006 Australia Department of Electrical and Computer Engineering University of Pittsburgh PittsburghPA15261 United States JD Finance America Corporation Mountain View CaliforniaCA94043 United States

Automated and accurate segmentation of the infected regions in computed tomography (CT) images is critical for the prediction of the pathological stage and treatment response of COVID-19. Several deep convolutional neural networks (DCNNs) have been designed for this task, whose performance, however, tends to be suppressed by their limited local receptive fields and insufficient global reasoning ability. In this paper, we propose a pixel-wise sparse graph reasoning (PSGR) module and insert it into a segmentation network to enhance the modeling of long-range dependencies for COVID-19 infected region segmentation in CT images. In the PSGR module, a graph is first constructed by projecting each pixel on a node based on the features produced by the segmentation backbone, and then converted into a sparsely-connected graph by keeping only K strongest connections to each uncertain pixel. The long-range information reasoning is performed on the sparsely-connected graph to generate enhanced features. The advantages of this module are two-fold: (1) the pixel-wise mapping strategy not only avoids imprecise pixel-to-node projections but also preserves the inherent information of each pixel for global reasoning;and (2) the sparsely-connected graph construction results in effective information retrieval and reduction of the noise propagation. The proposed solution has been evaluated against four widely-used segmentation models on three public datasets. The results show that the segmentation model equipped with our PSGR module can effectively segment COVID-19 infected regions in CT images, outperforming all other competing models. Copyright © 2021, The Authors. All rights reserved.

关键词： Pixels

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COVID-19大流行期间流感活动呈“断崖式”下降——佩戴口罩、人员流动变化及SARS-CoV-2干扰的作用

引用

engineering 2023年第2期21卷 195-202,M0008页

作者：韩莎莎张婷吕岩赖圣杰戴佩希郑建东杨维中周晓华冯录召 Beijing International Center for Mathematical Research Peking UniversityBeijing 100871China Harvard Medical School Harvard UniversityBostonMA 02115USA School of Population Medicine and Public Health Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China WorldPop School of Geography and Environmental ScienceUniversity of SouthamptonSouthampton SO171BJUK Division for Infectious Diseases Chinese Center for Disease Control and PreventionBeijing 102206China Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijing 100871China National Engineering Laboratory of Big Data Analysis and Applied Technology Peking UniversityBeijing 100871China

一般情况下,每年冬季是季节性流感高发季节,但在当前2019冠状病毒病(COVID-19)大流行期间,全球季节性流感活动呈“断崖式”下降。为应对即将到来的流感季节,亟需弄清这种前所未有的流感低水平流行的原因。本文中,我们探索了一种国家特... 详细信息

一般情况下,每年冬季是季节性流感高发季节,但在当前2019冠状病毒病(COVID-19)大流行期间,全球季节性流感活动呈“断崖式”下降。为应对即将到来的流感季节,亟需弄清这种前所未有的流感低水平流行的原因。本文中,我们探索了一种国家特异性推理模型,利用该模型估计中国、英国和美国这三个国家中佩戴口罩、人员流动变化(国际和国内)以及严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)干扰的影响。结果发现,在这些地区增加一周佩戴口罩的干预措施,流感活动可减少11.3%~35.2%。实施一周的限制人员流动措施对国际(1.7%~6.5%)和国内社区(1.6%~2.8%)的影响较小。2020年至2021年,仅佩戴口罩这一项干预措施就可使阳性率下降13.3%至19.8%。仅人员流动变化可使阳性率降低5.2%至14.0%,其中79.8%~98.2%归因于国际旅行限制。SARS-CoV-2干扰仅在2019年至2020年具有统计学显著效应。中国北方地区及英国的阳性百分比分别降低7.6%(2.4~14.4)和10.2%(7.2~13.6)。探索所得出的结果对了解非药物干预措施和其他呼吸系统疾病背景下的流感演变有一定意义,有助于制定卫生政策,并可为公共卫生措施的个性化设计提供信息。

关键词：卫生政策非药物干预呼吸系统疾病流行期间季节性流感流动变化个性化设计模型估计

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