The Broad Learning System (BLS) has been extensively developed and applied across various fields due to its significant advantages, including high efficiency, strong generality, and scalability. However, in practical ...
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With the ongoing trend of vehicle automation and electrification, the future will present a mixed traffic environment with different automation and energy consumption types. However, current research focuses more on f...
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Multi-object tracking (MOT) using vision sensors remains a challenging problem, particularly in dynamic backgrounds and severe occlusions. Existing methods, relying on holistic appearance or spatial cues, fail to capt...
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The Service-Based Architecture (SBA) introduced by 3GPP allows the control plane of 5G Core Network (CN) to function through a set of interconnected Network Functions (NFs), which offers significant benefits such as i...
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Abstract: In this paper, motivated by previous related works on a kind of quantum local adiabatic evolution, we mainly study the circuit model of its corresponding quantum global adiabatic search algorithm, in which t...
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In the last decades, free-floating car sharing (FFCS) has become a fast-growing mode of mobility service and promoted in many cities across the world. While lots of researchers have paid increasing attention to FFCS i...
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Parallel decoding of backscatter improves communication throughput by enabling concurrent transmission of backscatter tags. In practical applications of parallel decoding, it is extremely difficult to distinguish coll...
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The scarcity of annotations has become a significant obstacle in training powerful deep-learning models for medical image segmentation, limiting their clinical application. To overcome this, semi-supervised learning t...
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Given the critical role of rotating machinery in industrial cyber-physical systems (ICPS), ensuring their reliable operation is essential for the stability and safety of ICPS. Deep neural networks have demonstrated co...
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The CRISPR-Cas9 system, found across bacteria and archaea, enables efficient genome engineering in eukaryotic cells. There is a challenge that Cas9 guide RNA may cause off-target activities. Although numbers of method...
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The CRISPR-Cas9 system, found across bacteria and archaea, enables efficient genome engineering in eukaryotic cells. There is a challenge that Cas9 guide RNA may cause off-target activities. Although numbers of methods have been proposed to predict off-target activities in guide RNA designing, this procedure involves numerous potential off-target sites, which causes label imbalance problem. To address this problem, we developed a deep learning framework, named CAF-Net (Cas9 Augmentation and Finetune Network), for predicting off-target activities of CRISPR-Cas9. First, we pretrain an embedding model to extract features from target and guide sequence pairs. Subsequently, data augmentation is applied to these features. And finally, the model is finetuned with synthetic samples. Evaluation results demonstrate its performance on published datasets.
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