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GhLPF1 Associated Network Is Involved with Cotton Lint Percentage Regulation Revealed by the Integrative Analysis of Spatial Transcriptome

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advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025年第13期12卷 e2414175页

作者： Hongyu Wu Luyao Wang Shengjun Zhao Mengtao Gao Junfeng Cao Yupeng Hao Li Yu Ting Zhao Siyuan Wang Jin Han Yumeng Zhu Yongyan Zhao Jie Li Ke Nie Kening Lu Linyun Ding Zhiyuan Zhang Tianzhen Zhang Xueying Guan Zhejiang Provincial Key Laboratory of Crop Genetic Resources Institute of Crop Science Plant Precision Breeding Academy College of Agriculture and Biotechnology Zhejiang University Hangzhou 300058 China. Yazhou Bay Science and Technology City Hainan Institute of Zhejiang University Building 11 Yongyou Industrial Park Yazhou District Sanya Hainan 572025 China. National Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization Ministry of Agriculture Nanjing Agricultural University Nanjing 210095 China. Key Laboratory of Plant Nutrition and Fertilization in Low-Middle Reaches of the Yangtze River Ministry of Agriculture Nanjing Agricultural University Nanjing 210095 China. School of Life Sciences Centre for Cell & Developmental Biology and State Key Laboratory of Agrobiotechnology The Chinese University of Hong Kong Shatin Hong Kong 999077 China. Institute of Leisure Agriculture Jiangsu Academy of Agricultural Sciences Nanjing 210014 China. Seed Production and Quality Control Research Center Hainan Seed Industry Laboratory Sanya Hainan China.

Cotton fibers, derived from the epidermis of the ovule, provide a sustainable natural fiber source for the textile industry. Traits related to fiber yield are predominantly determined by molecular regulations in the epidermis of the outer integument (OI) region of the cotton ovule. Here, we identify an R2R3 MYB transcription factor coding gene GhLPF1 within the QTL-LP-ChrA06 locus for lint percentage (LP, percentage of lint to seed cotton) through constructing the 1-Day Post Anthesis Cotton Ovule Spatial Transcriptome Atlas. GhLPF1 is subjected as a downstream target of miR828 during fiber development. The direct downstream genes (DDGs) of GhLPF1 are biased to increased expression in GhLPF1-CR, and are preferentially expressed in OI, so that GhLPF1 is primarily a transcriptional repressor to its DDGs. Population-wide transcriptome analysis confirms that expression variation of GhLPF1-DDGs is significantly biased to negative correlation with LP, among which a type I homeobox protein-coding gene GhHB6 is further validated to be the directly downstream gene of GhLPF1. Given these data, it is demonstrated that GhLPF1 mediates a regulation network in LP as a transcriptional repressor, which makes it a valuable functional marker for fiber-trait improvement application from QTL-LP-ChrA06.

关键词： fiber regulation population‐wide transcriptome analysis post‐transcriptional regulation spatial transcriptome

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Gradient piezoelectric composites for ultrasonic transducer design and imaging applications

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Journal of Materiomics 2025年第6期11卷

作者： Chenxue Hou Zhaoxi Li Chunlong Fei Qibo Lin Xiaofei Luo Xiongwei Wei Yiheng Yang Qi Lu Yi Quan Guangzhi Dong Zeyu Chen Xiaozhou Lü Weimin Bao Yintang Yang Shaanxi Provincial Key Laboratory of Integrated Circuit and System Integration Faculty of Integrated Circuit Xidian University Xi'an 710071 China The State Key Laboratory of Analog and Mixed-Signal VLSl Institute of Microelectronics University of Macau Macao 999078 China School of Aerospace Science and Technology Xidian University Xi'an 710071 China State Key Laboratory of Precision Manufacturing for Extreme Service Performance College of Mechanical and Electrical Engineering Central South University Changsha 410083 China College of Automotive and Mechanical Engineering Changsha University of Science and Technology Changsha 410114 China Hunan Province University Key Laboratory of Intelligent Testing and Control Technology for Engineering Equipment Changsha 410114 China School of Advanced Materials and Nanotechnology Xidian University Xi'an 710126 China Furong Laboratory (Precision Medicine) Changsha 410008 China National Engineering Research Center of Personalized Diagnostic and Therapeutic Technology Xiangya Hospital Central South University Changsha 410008 China Hunan Engineering Research Center of Skin Health and Disease Xiangya Hospital Central South University Changsha 410008 China

Ultrasonic imaging technology has advanced rapidly, the escalating demand for imaging quality has driven the continuous development of ultrasonic transducers featuring high-performance. Among them, the crucial factors constraining the further enhancement of imaging quality are the frequency of the device and the intensity of the echo signal. Piezoelectric composites have become a hotspot for ultrasonic transducers and imaging applications due to their excellent properties. However, due to the limitations of the accuracy of the cutting process, the development of piezoelectric/polymer composites is often undermined by undesirable pseudo-vibrations, especially in high-frequency applications, which will significantly reduce energy conversion efficiency. In this study, a novel design method of 1–3 piezoelectric composites with gradient nanoparticle doped polymer is proposed to eliminate the undesired lateral vibrations. Based on the optimized composites, a high-performance composite ultrasonic transducer with a center frequency of 8.51 MHz is prepared. Compared with the traditional composite transducer, the optimized transducer improves the echo voltage amplitude significantly, reaching nearly 3 times. The above advantages are further verified in high-quality ultrasound and photoacoustic imaging. The optimization method has valuable guidance for the design of high-frequency composite transducers, which have great potential in ultrasonic and photoacoustic imaging applications.

关键词： Piezoelectric composites Ultrasonic transducer Imaging applications Lateral vibration Finite element analysis

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Preface——Special Issue on New Directions in Nonlinear and Distributed control

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Journal of Systems Science & Complexity 2018年第1期31卷 1-3页

作者： LIU Tengfei XIN Bin JIANG Zhong-Ping State Key Laboratory of Synthetical Automation for Process Industries Northeastern University Shenyang 110819 China School of Automation State Key Laboratory of Intelligent Control and Decision of Complex Systems Beijing Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of Technology Beijing 100081 China Tandon School of Engineering New York University Brooklyn NY 11201 USA

Nonlinearity is ubiquitous in engineering and natural *** development of nonlinear control can be traced back to decades *** date,the research has reached the stage that emphasizes developing methodologies that can ha... 详细信息

关键词：控制问题非线性分布式工程应用程序电子物理自然系统生产线相互作用

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Optimization of Island Integrated Energy System based on Marine Renewable Energy

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Fundamental Research 2024年

作者： Wen Zhao Bohong Wang Ting Pan Yujie Chen Hengcong Tao Baoying Guo Petar Sabev Varbanov Jinshu Lu National-Local Joint Engineering Laboratory of Harbour Oil & Gas Storage and Transportation Technology/Zhejiang Key Laboratory of Petrochemical Environmental Pollution Control Zhejiang Ocean University No.1 Haida South Road 316022 Zhoushan P.R. China Sustainable Process Integration Laboratory – SPIL NETME Centre Faculty of Mechanical Engineering Brno University of Technology - VUT Technická 2896/2 616 00 Brno Czech Republic School of Mechanical Engineering Beijing Institute of Petrochemical Technology Beijing 102617 China Marine Science and Technology College Zhejiang Ocean University Zhoushan 316022 China Széchenyi István University H-9026 Győr Egyetem tér 1 Hungary School of Naval Architecture and Maritime Zhejiang Ocean University Zhoushan 316022 Zhejiang China

Integrating marine renewable energy (MRE) with conventional energy sources and logically constructing island energy systems is crucial for alleviating island energy supply challenges and helping coastal energy systems achieve a sustainable, low-carbon transition. In this study, the status of marine energy utilisation technologies is reviewed, with a focus on advancements in energy conversion equipment, grid integration, and energy storage. The economic feasibility and environmental sustainability of marine energy systems are comparatively analysed to enhance the development and utilisation of marine energy technology while reducing the economic cost of power generation. Suitable equipment is highlighted for islands, with efficient energy generation strategies proposed to achieve cleaner, localised, and cost-effective island integrated energy system (IIES) design. Island energy facilities vary, and integrated development is crucial for building new energy systems. Based on the types and resources of island energy, IIESs are constructed for hierarchical energy utilisation and multi-energy coupling, coordinating resources to achieve source–grid–load–storage integration. The optimisation of IIESs is reviewed, with a focus on modelling methods, intelligent algorithm development, and system simulation. This study differs from previous research as it considers the integration of marine energy into existing systems to achieve comprehensive integration of multiple energy sources. Additionally, optimisation and solution methods for IIES models are summarised. To integrate complex, multivariable energy systems and create stable and predictable outputs, marine energy and load forecasting methods are explored. Overall, this study supports the advancement of marine energy utilisation, focusing on its progressive integration into island energy systems as the efficiency of marine energy improves. This work aims to inspire the development of new functions and modules based on existi

关键词： Marine Renewable Energy Energy Conversion and Storage Island Integrated Energy System process Systems Engineering process Integration

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Investigation into neuroleptic malignant syndrome triggered by atypical antipsychotics: Insights from FDA adverse event reporting system database

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Journal of affective disorders 2025年 386卷 119481页

作者： Jinhao He Xuehu Luo Cong Li Wei Zhong Mo Sun Chenning Zhang Department of Pharmacy The Third Affiliated Hospital of Chengdu Medical College Chengdu Pidu District People's Hospital Chengdu 611730 Sichuan China. School of Biological Sciences Georgia Institute of Technology Atlanta GA 30332 USA. Department of Pharmacy Xiangyang No.1 People's Hospital Hubei University of Medicine Xiangyang 441000 Hubei China National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture Jiangsu Kanion Pharmaceutical Co. Ltd. Lianyungang 222001 China. Electronic address: zhangcn1118@***.

OBJECTIVE:Neuroleptic malignant syndrome (NMS) is a rare but potentially life-threatening reaction associated with dopamine antagonists, particularly typical antipsychotics. Despite the relatively low incidence of NMS linked to atypical antipsychotics (AAPs), there is a notable lack of extensive real-world studies investigating this condition. METHODS:This study utilizes data from the FDA Adverse Event Reporting System (FAERS) from 2004 to 2024, employing disproportionality analysis to explore the association between fourteen commonly prescribed AAPs and NMS. Multivariate logistic regression was conducted to identify risk factors for mortality related to NMS. RESULTS:We analyzed 79,980 primary suspected adverse drug event (ADE) reports for NMS, revealing a slight male predominance and a median age of 48 years (Interquartile Range [IQR]: 31-64). Patients were primarily located in Europe and the United States. Ziprasidone exhibited the strongest pharmacovigilance signal (Reporting Odds Ratio [ROR] = 3.09; 95 % confidence interval [CI]: 2.97-3.21), while lurasidone showed the lowest signal strength (ROR = 1.58; 95 % CI: 1.52-1.65). The median time to onset of NMS was 42 days (IQR: 9-328.25). Significant mortality risk factors included age ≥ 65 years (Odds Ratio [OR] = 4.45; 95 % CI: 3.33-5.95), Parkinson's disease (OR = 32.69; 95 % CI: 14.75-72.46), and malignant hyperthermia (OR = 25.23; 95 % CI: 8.62-73.83), with an area under the curve (AUC) of 0.877. CONCLUSION:This study provides vital pharmacovigilance insights regarding NMS related to AAPs, enhancing the understanding of its clinical implications.

关键词： Adverse drug events Atypical antipsychotic FAERS Neuroleptic malignant syndrome

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Reduced dietary nitrogen with a high Lys:CP ratio restricted dietary N excretion without negatively affecting weaned piglets

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Animal Nutrition 2019年第2期5卷 115-123页

作者： Hongnan Liu Li Wu Hui Han Yuying Li Lijian Wang Jie Yin Wenjun Fan Miaomiao Bai Jiming Yao Xingguo Huang Tiejun Li Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process Key Laboratory of Agro-Ecological Processes in Subtropical RegionNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry ProductionInstitute of Subtropical AgricultureChinese Academy of SciencesChangsha410125China Hunan Co-Innovation Center of Animal Production Safety Changsha410128China University of Chinese Academy of Sciences Beijing100039China Department of Animal Science Hunan Agriculture UniversityChangsha410128China Guangdong Wangda Group Academician Workstation for Clean Feed Technology Research and Development in Swine Guangdong Wangda Group Co.Ltd.Guangzhou510663China

We hypothesized that balancing the content of exogenous amino acids, especially lysine, to reduce protein content in swine diets could reduce nitrogen(N) pollution associated with animal husbandry. Two experiments(45 d each experiment) were performed on weaned piglets(Duroc x Landrace x Yorkshire,28 d of age) to test this and to determine the optimal lysine to crude protein(Lys:CP) ratio in diet. In Exp. 1,12 piglets(6 replicates [n = 6]) were fed diets containing different levels of CP(17% and 20%) but the same level of Lys, Increased CP content resulted in significant increases(P < 0.05) of average daily gain(ADG), average daily feed intake(ADFI), and body weight(BW);but did not affect the feed to gain ratio. In Exp. 2,24 piglets(8 replicates [n = 8]) were fed 1 of 3 diets as follows: 1) 20% CP with a regular Lys:CP ratio(6.23%, control);2) 17% CP with a reduced Lys:CP ratio(6.14%, LL);or 3) 17% CP with a standard Lys:CP ratio(7.32%, SL). The ADG, final BW, serum concentrations of growth hormone and insulin-like growth factor-1, villus height in the jejunum, and villus height to crypt depth ratio were the lowest in piglets fed LL diet, whereas blood urea N concentration was the lowest and the value of lipase activity was the highest in the piglets fed SL diet. The SL diet did not affect growth performance,intestinal morphology, or serum hormone concentrations, indicating that reduced dietary N with a high Lys:CP ratio can efficiently reduce dietary N excretion without negatively affecting weaned piglets.

关键词： Protein Lysine Feeding Digestion Nutrition Genetic mapping

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SPAHN novel approach for PL-AG gateway discovery for internet connectivity

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Peer-to-Peer Networking and Applications 2020年第4期14卷 2275-2284页

作者： Kannan, K. Sivaranjani, P. Sathish Kumar, S. Nalini, M. Balaji, V. R. Sanjeevi, P. Department of ECE R.M.K. College of Engineering and Technology Chennai India Department of Electronics and communication Engineering Kongu Engineering College Erode India Dept of Electrical and Electronics Engineering M. Kumarasamy College of Engineering Thalavapalayam India Department of Computer Science and Engineering Saveetha School of Engineering Saveetha Institute of Medical and Technical Sciences Chennai India Department of ECE Sri Krishna College of Engineering and Technology Coimbatore India Key Laboratory of Advanced Process Control for Light Industry Ministry of Education Jiangnan University Wuxi China

Internet Gateway(IGW) main role is detecting availability nodes and providing internet to Mobile Ad Hoc Network(MANET) have whenever connected to internet. Discovery time of gateway is changed based on the throughput and packet delay. Many of the situations the mobile nodes are have fixed host connection to the internet using minimum hop path, it is not good for waiting packets because of that packets are have longer path interface queue. This research paper object is avoided above the problem mentioning using a novel approach of SPAHN (Solving Problem of Ad-Hoc Network). This paper mainly focus is classify the routing protocols of load-aware in MANET and from this classify discover the proactive load-aware gateway (PL-AG) from a device into interface queue size and min-hop-metric. This novel approach has been allowing and gives better handoff between two internet gateways for fixed host seamless connectivity. We justify the performance of the SPAHN approach using two metrics like average end-to-end delay and throughput based on this examination the SPAHN system yield good simulation results comparably existing systems.

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Corrigendum to ‘Graphical pinch analysis-based method for heat exchanger networks retrofit of a residuum hydrogenation process’ [Energy volume 299 (2024) 131538]

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Energy 2024年 310卷

作者： Keke Zhi Bohong Wang Lianghui Guo Yujie Chen Wei Li Paweł Ocłoń Jin Wang Yuping Chen Hengcong Tao Xinze Li Petar Sabev Varbanov China University of Petroleum-Beijing at Karamay Karamay China National & Local Joint Engineering Research Center of Harbor Oil & Gas Storage and Transportation Technology/Zhejiang Key Laboratory of Petrochemical Environmental Pollution Control Zhejiang Ocean University No. 1 Haida South Road 316022 Zhoushan China School of Mechanical Engineering Beijing Key Laboratory of Pipeline Critical Technology and Equipment for Deepwater Oil & Gas Development Beijing Institute of Petrochemical Technology Beijing 102617 China Jiangsu Key Laboratory of Process Enhancement and New Energy Equipment Technology School of Mechanical and Power Engineering Nanjing Tech University Nanjing 211816 China Cracow University of Technology Faculty of Environmental and Energy Engineering Energy Department Al. Jana Pawła II 37 31-864 Cracow Poland School of Energy and Environmental Engineering Hebei University of Technology Tianjin 300401 China Zhejiang Petrochemical Co. Ltd Yushan Island Zhoushan China Széchenyi István University H-9026 Győr Egyetem tér 1 Hungary

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Photocatalytic Oxidative Coupling of Methane over Au1Ag Single-Atom Alloy Modified ZnO with Oxygen and Water Vapor: Synergy of Gold and Silver

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Angewandte Chemie 2023年第42期135卷

作者： Yuxiong Wang Guang Hong Yaoyu Zhang Prof. Yue Liu Dr. Wanglai Cen Prof. Lianzhou Wang Prof. Zhongbiao Wu Key Laboratory of Environment Remediation and Ecological Health Ministry of Education College of Environmental and Resource Sciences Zhejiang University Hangzhou 310058 China Institute of New Energy and Low-Carbon Technology National Engineering Research Center for Flue Gas Desulfurization Sichuan University Chengdu 610207 China Zhejiang Provincial Engineering Research Center of Industrial Boiler & Furnace Flue Gas Pollution Control Hangzhou 310058 China Nanomaterials Centre School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology The University of Queensland St Lucia QLD 4072 Australia

C−H dissociation and C−C coupling are two key steps in converting CH 4 into multi-carbon compounds. Here we report a synergy of Au and Ag to greatly promote C 2 H 6 formation over Au 1 Ag single-atom alloy nanoparticles (Au 1 Ag NPs)-modified ZnO catalyst via photocatalytic oxidative coupling of methane (POCM) with O 2 and H 2 O. Atomically dispersed Au in Au 1 Ag NPs effectively promotes the dissociation of O 2 and H 2 O into *OOH, promoting C−H activation of CH 4 on the photogenerated O − to form *CH 3 . Electron-deficient Au single atoms, as hopping ladders, also facilitate the migration of electron donor *CH 3 from ZnO to Au 1 Ag NPs. Finally, *CH 3 coupling can readily occur on Ag atoms of Au 1 Ag NPs. An excellent C 2 H 6 yield of 14.0 mmol g −1 h −1 with a selectivity of 79 % and an apparent quantum yield of 14.6 % at 350 nm is obtained via POCM with O 2 and H 2 O, which is at least two times that of the photocatalytic system. The bimetallic synergistic strategy offers guidance for future catalyst design for POCM with O 2 and H 2 O.

关键词： Ethane Methane Oxidative Coupling Photocatalysis Single-Atom Alloy

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$H_{\infty}$ Output Tracking control for Networked Systems With Adaptively Adjusted Event-Triggered Scheme

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IEEE Transactions on Systems, Man, and Cybernetics: Systems 2019年第10期49卷 2050-2058页

作者： Huaicheng Yan Chenyang Hu Hao Zhang Hamid Reza Karimi Xiaowei Jiang Ming Liu Key Laboratory of Advanced Control and Optimization for Chemical Process of Ministry of Education East China University of Science and Technology Shanghai China School of Information Science and Engineering East China University of Science and Technology Shanghai China Department of Control Science and Engineering Tongji University Shanghai China Department of Mechanical Engineering Politecnico di Milan Milan Italy College of Mechatronics and Control Engineering Hubei Normal University Huangshi China Research Center of Satellite Technology Harbin Institute of Technology Harbin China

The H ∞ output tracking control problem of the networked control systems (NCSs) under an adaptively adjusted event-triggered scheme is investigated in this paper. Firstly, a novel adaptively adjusted event-triggered scheme developed in the NCSs with stochastic sensor faults is proposed to choose the necessary packets of sampled data to be transmitted through the networks. Then, the considered system is described as a time-delay system with a delay-distribution for investigation. Based on the established model, a novel stability criterion and the state-feedback controller design with a desired performance of H ∞ output tracking control for the systems are both derived by using Lyapunov functional. An algorithm is also presented to explain the process of adaptively adjusted event-triggered scheme method. Finally, a satellite tracking case is provided to demonstrate the effectiveness of the proposed approach.

关键词： Bandwidth Delays Actuators Communication networks Symmetric matrices Networked control systems

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