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Cloud-based solution to identify statistically significant MS peaks differentiating sample categories

BMC Research Notes 2013年第1期6卷 1-4页

作者： Ji, Jun Ling, Jeffrey Jiang, Helen Wen, Qiaojun Whitin, John C. Tian, Lu Cohen, Harvey J. Ling, Xuefeng B. Departments of Surgery Stanford University Stanford CA 94305 United States Departments of Pediatrics Stanford University Stanford CA 94305 United States Departments of Health Research and Policy Stanford University Stanford CA 94305 United States State Key Laboratory of Industrial Control Technology Institute of Industrial Process Control Zhejiang University Hangzhou 310027 China

Background: Mass spectrometry (MS) has evolved to become the primary high throughput tool for proteomics based biomarker discovery. Until now, multiple challenges in protein MS data analysis remain: large-scale and complex data set management;MS peak identification, indexing;and high dimensional peak differential analysis with the concurrent statistical tests based false discovery rate (FDR). "Turnkey" solutions are needed for biomarker investigations to rapidly process MS data sets to identify statistically significant peaks for subsequent validation. Findings. Here we present an efficient and effective solution, which provides experimental biologists easy access to "cloud" computing capabilities to analyze MS data. The web portal can be accessed at. Conclusions: Presented web application supplies large scale MS data online uploading and analysis with a simple user interface. This bioinformatic tool will facilitate the discovery of the potential protein biomarkers using MS. © 2013 Ji et al.;licensee BioMed Central Ltd.

关键词： Mass Spectrometry Data Simple Object Access Protocol Common Gateway Interface Local False Discovery Rate Protein Mass Spectrometry

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Multi-objective mathematic programming model and algorithm for production planning in steel and iron enterprise

Multi-objective mathematic programming model and algorithm f...

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Chinese control Conference (CCC)

作者： Shan Lu Hong-ye Su Li Zhu Qinghong Shen National Key Laboratory of Industrial Control Technology Institute of Cyber-Systems and Control Zhejiang University Hangzhou 310027 China

As iron and steel products demand becomes increasingly diversified and batch reduced, make-to-order production has gradually satisfied the demand of modern iron and steel enterprises. It is significant for optimization of the make-to-order production planning to guarantee punctual delivery considering inventory, production capacity, processes and product specification. A multi-objective mixed integer nonlinear programming (MINLP) model is formulated to optimize the production, and a hybrid particle swarm optimization algorithm is developed to solve the model. A case study based on the order data of a steel and iron enterprise is presented. Compared with the optimization strategy upon particle swarm optimization and manual scheduling, the proposed optimization model and strategy effectively reduce losses caused by back order, inventory storage and unbalanced production capacity, and provide a reference and guidance for the operation.

关键词： Steel Iron Particle swarm optimization Programming Production planning Optimization

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ZnO/CuS heterostructured nanocomposite and its organic functionalisation

ZnO/CuS heterostructured nanocomposite and its organic funct...

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12th IUMRS International Conference on advanced Materials(IUMRS-ICAM2013)

作者： Q.Cong X.He M.Gao X.Ma G.Li School of Environmental and Material Engineering Center of Advanced Functional MaterialsYantai University State Key Laboratory of Silicon Materials Zhejiang University National Laboratory of Industrial Control Technology Institute of CyberSystems and ControlZhejiang University

In order to extend the visible light response of ZnO, ZnO/Cu S nanocomposite with heterostructure was prepared by a simple two-step hydrothermal synthesis. The as prepared ZnO/Cu S heterostructured nanocomposite was characterised by SEM, photoluminescence, ultraviolet–visible spectroscopy and X-ray diffraction. On the other hand, chitosan is considered as a very promising natural biopolymer. It holds not only abundant resource and low cost but also has excellent adsorption properties to a broad range of organic pollutants and some heavy metal *** improve the adsorption properties of ZnO/Cu S heterostructured nanocomposite, a water soluble chitosan containing carboxyl groups was synthesised with graft *** modification of ZnO/Cu S heterostructured nanocomposite was carried out utilising the self-assembly process between hydroxyl groups of ZnO/Cu S nanocomposite and carboxyl groups of water soluble chitosan. Comparative tests before and after surface modification were performed with Fourier transform infrared spectroscopy. To examine the surface and interface properties of nanocomposites, chemical prototype sensor arrays were constructed based on ZnO, ZnO/Cu S nanocomposite, and ZnO/Cu S nanocomposite modified with chitosan containing carboxyl groups and quartz crystal microbalance devices. The adsorption response behaviours of the sensor arrays to some typical volatile compounds were examined. The results indicated that, with comparison to ZnO nanostructure, the ZnO/Cu S nanocomposite exhibited enhanced adsorption properties to some typical volatile compounds dramatically, and the effect of one layer modification on the surface adsorption properties of ZnO/Cu S nanocomposite is also very evident and useful, which provides a microenvironment of biocompatibility for ZnO/Cu S *** same time, ZnO/Cu S nanocomposite showed broadening visible light response and hence has good potential applications in new energy materials, photocatalysts

关键词： ZnO based nanocomposite,Heterostructures,Surface and interface properties,Self-assembly surface modification,Device arrays,Enhanced sensitivity

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Surface modification of ZnO nanosheets with Au/polyaniline and their properties

Surface modification of ZnO nanosheets with Au/polyaniline a...

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12th IUMRS International Conference on advanced Materials(IUMRS-ICAM2013)

作者： Q.Cong H.Geng X.He M.Gao X.Ma G.Li School of Environmental and Material Engineering Center of Advanced Functional MaterialsYantai University State Key Laboratory of Silicon Materials Zhejiang University National Laboratory of Industrial Control Technology Institute of CyberSystems and ControlZhejiang University

ZnO has many potential applications, such as, solar cells, photocatalysts, chemical sensors and biosensors. However, to extend its visible light response is still a great challenge. In this paper,ZnO nanosheets were prepared by a wet chemical method. The surface treatment of ZnO nanosheets was carried out using chloroauric acid, and then reduced with aniline. A series of characterisations were examined by TEM(transmission electron microscopy), XRD(X-ray diffraction), the Fourier transform infrared(FTIR) spectra and ultraviolet-visible spectroscopy(UVvis). The experimental results indicated that ZnO nanosheets modified with a thin layer of Au/PANi composite exhibited wide visible light response. A chemical prototype sensor was constructed based on the ZnO/Au/polyaniline nanocomposites prepared and interdigital electrodes on flexible polymer substrates. The effects of surface treatment of ZnO nanosheets on the gas sensing behaviours were examined. The results indicated that the effective conductive channels for charge transfer and separation were formed due to the Au/polyaniline necklaces attached on the surface of ZnO nanosheets, and the type of conductivity of ZnO/Au/polyaniline nanocomposite changed to P-type from N-type with increasing the amounts of chloroauric acid. When the synthesis parameter of ZnO/Au/polyaniline nanocomposite was optimised, the gas sensitivity of ZnO/Au/PANi(polyaniline) was superior to that of PANi nanowire prepared under similar synthesis condition, and it has been found that this kind of nanocomposite not only possesses widening light response, harvests more visible light, but also presents effective channels for charge transfer. It would be useful in potential applications in photocatalysts or other fields.

关键词： ZnO Nano/microstructures,Surface modification,Nanocomposite,Broadening visible light response,Sensitive mechanism

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Sufficient and Necessary Condition of Admissibility for Fractional-order Singular System

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自动化学报 2013年第12期39卷 2160-2164页

作者： YU Yao JIAO Zhuang SUN Chang-Yin School of Automation Electrical Engineering University of Science and Technology Beijing Beijing 100083 China Key Laboratory of Advanced Control of Iron and Steel Process Ministry of Education Beijing 100083 China Beijing Institute of Elec- tronic System Engineering Beijing 100854 China

这份报纸与顺序为部分顺序的单个系统集中于考虑条件吗？(0， 1 ) 。整齐的定义，没有推动并且考虑被给第一，然后，为部分顺序的单个系统的考虑的一个足够、必要的条件被建立。一个数字例子被包括说明建议条件。

关键词：奇异系统分数阶充要条件可容许充分必要条件

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分数阶奇异系统容许性的充分必要条件(英文)

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自动化学报 2013年第12期39卷 2160-2164页

作者：余瑶焦壮孙长银 School of Automation & Electrical Engineering University of Science and Technology Beijing Key Laboratory of Advanced Control of Iron and Steel Process Ministry of Education Beijing Institute of Electronic System Engineering

This paper focuses on the admissibility condition for fractional-order singular system with order α∈(0, 1). The definitions of regularity, impulse-free and admissibility are given first, then a sufcient and necessary condition of admissibility for fractional-order singular system is established. A numerical example is included to illustrate the proposed condition.

关键词： Fractional-order singular systems regularity impulse-free admissibility

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What is the uniqueness of growth pattern in human flesh search organization?

What is the uniqueness of growth pattern in human flesh sear...

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Pacific Asia Workshop on Intelligence and Security Informatics, PAISI 2013

作者： Wang, Tao Zhang, Qingpeng Fu, Julei Wang, Xiao Zheng, Suncong College of Information System and Management National University of Defense Technology Changsha 410073 China State Key Laboratory of Management and Control for Complex Systems Institute of Automation Chinese Academy of Sciences Beijing 100190 China Department of Systems and Industrial Engineering University of Arizona Tucson AZ United States

ISBN: (纸本)9783642396922

Human Flesh Search is an explosive Web phenomenon these years in China, especially when new media, such as Weibo, appeared. In this research, we present the empirical studies about growing patterns of participated Human Flesh Search user, and unveiled one unique growing property. Based on the empirical findings, we compare it with two others results, one is the common Weibo's growth pattern, and the other is the popularity growth pattern of photo in Flickr. Some differences are proposed and analyzed briefly. © 2013 Springer-Verlag.

关键词： Social networking (online)

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Adaptive neural output feedback control for stochastic nonlinear systems with unknown control directions

Adaptive neural output feedback control for stochastic nonli...

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Chinese control Conference (CCC)

作者： Zhaoxu Yu Shugang Li Key Laboratory of Advanced Control and Optimization for Chemical Process of Ministry of Education East China University of Science and Technology Shanghai 200237 China Department of Industrial Engineering and Logistics Shanghai Jiao Tong University China 200240 China

This paper focuses on the problem of adaptive output feedback stabilization for a class of stochastic nonlinear system with unknown control directions. By using a linear state transformation, the unknown control coefficients are lumped together, such that the original system is transformed to a new system for which control design becomes feasible. By employing the input-driven observer, a novel adaptive neural network (NN) output-feedback controller which only contains one adaptive parameter is developed for such systems by using backstepping technique and NNs' parameterization. The proposed control design guarantees that all the signals in the closed-loop systems are 4-moment semi-globally uniformly ultimately bounded.

关键词： Adaptive systems Artificial neural networks Nonlinear systems control design Observers

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Fine-grained image classification using color exemplar classifiers

Fine-grained image classification using color exemplar class...

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14th Pacific-Rim Conference on Multimedia, PCM 2013

作者： Zhang, Chunjie Xiong, Wei Liu, Jing Zhang, Yifan Liang, Chao Huang, Qingming School of Computer and Control Engineering University of Chinese Academy of Sciences 100049 Beijing China National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences P.O. Box 2728 Beijing China National Engineering Research Center for Multimedia Software Wuhan University 430072 Wuhan China Key Lab of Intell. Info. Process Institute of Computing Technology Chinese Academy of Sciences Beijing 100190 China

ISBN: (纸本)9783319037301

The use of local features has demonstrated its effectiveness for many visual applications. However, local features are often extracted with gray images. This ignores the useful information within different color channels which eventually hinders the final performance, especially for fine-grained image classification. Besides, the semantic information of local features is too weak to be applied for high-level visual applications. To cope with these problems, in this paper, we propose a novel fine-grained image classification method by using color exemplar classifiers. For each image, we first decompose it into multiple color channels to take advantage of the color information. For each color channel, we represent each image with a response histogram which is generated by exemplar classifiers. Experiments on several public image datasets demonstrate the effectiveness of the proposed color exemplar classifier based image classification method. © Springer International Publishing Switzerland 2013.

关键词： Image classification

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Sufficient and Necessary Condition of Admissibility for Fractional-order Singular System

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Acta Automatica Sinica 2013年第12期39卷 2160-2164页

作者： Yao YU Zhuang JIAO Chang-Yin SUN School of Automation & Electrical Engineering University of Science and Technology Beijing Beijing 100083 China Key Laboratory of Advanced Control of Iron and Steel Process Ministry of Education Beijing 100083 China Beijing Institute of Electronic System Engineering Beijing 100854 China

This paper focuses on the admissibility condition for fractional-order singular system with order α ∈ (0, 1). The definitions of regularity, impulse-free and admissibility are given first, then a sufficient and necessary condition of admissibility for fractional-order singular system is established. A numerical example is included to illustrate the proposed condition.

关键词： Fractional-order singular systems regularity impulse-free admissibility

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