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Milk fat globule membrane supplementation protects againstβ-lactoglobul-ininduced food allergy in mice via upregulation of regulatory T cells and enhancement of intestinal barrier in a microbiota-derived short-chain fatty acids manner

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Food science and Human Wellness 2024年第1期13卷 124-136页

作者： Han Gong Tiange Li Dong Liang Jingxin Gao Xiaohan Liu Xueying Mao Key Laboratory of Functional Dairy Ministry of EducationCollege of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100083China Henan Engineering Technology Research Center of Food Processing and Circulation Safety Control College of Food Science and TechnologyHenan Agricultural UniversityZhengzhou 450002China Applied Nutrition I China National Center for Food Safety Risk AssessmentBeijing 100022China

Milk fat globule membrane(MFGM),which contains abundant glycoproteins and phospholipids,exerts beneficial effects on intestinal health and *** aim of this study was to evaluate the protective effects and possible underlying mechanisms of MFGM on cow’s milk allergy(CMA)in aβ-lactoglobulin(BLG)-induced allergic mice *** was supplemented to allergic mice induced by BLG at a dose of 400 mg/kg body *** demonstrated that MFGM alleviated food allergy symptoms,decreased serum levels of lipopolysaccharide,pro-inflammatory cytokines,immunoglobulin(Ig)E,Ig G1,and Th2 cytokines including interleukin(IL)-4,while increased serum levels of Th1 cytokines including interferon-γand regulatory T cells(Tregs)cytokines including IL-10 and transforming growth factor-β.MFGM modulated gut microbiota and enhanced intestinal barrier of BLG-allergic mice,as evidenced by decreased relative abundance of Desulfobacterota,Rikenellaceae,Lachnospiraceae,and Desulfovibrionaceae,while increased relative abundance of Bacteroidetes,Lactobacillaceae and Muribaculaceae,and enhanced expressions of tight junction proteins including Occludin,Claudin-1 and zonula ***,MFGM increased fecal short-chain fatty acids(SCFAs)levels,which elevated G protein-coupled receptor(GPR)43 and GPR109A *** increased expressions of GPR43 and GPR109A induced CD103+dendritic cells accumulation and promoted Tregs differentiation in mesenteric lymph node to a certain *** summary,MFGM alleviated CMA in a BLG-induced allergic mice model through enhancing intestinal barrier and promoting Tregs differentiation,which may be correlated with SCFAs-mediated activation of *** findings suggest that MFGM may be useful as a promising functional ingredient against CMA.

关键词： Cow’s milk allergy Milk fat globule membrane Gut microbiota Short-chain fatty acid G protein-coupled receptor Regulatory T cell

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120 ppm Quality Factor Thermal Stability from -40 to +60 of a Dual-Axis MEMS Gyroscope Based on Joule Effect Dynamic control 36

120 ppm Quality Factor Thermal Stability from -40 to +60 of ...

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36th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2023

作者： Cui, Jian Zhao, Qiancheng Peking University National Key Laboratory of Science and Technology on Micro/Nano Fabrication School of Integrated Circuits Beijing China Beijing Advanced Innovation Center for Integrated Circuits Beijing China

ISBN: (纸本)9781665493086

This paper presents a novel calibration method to improve the thermal stability of the quality factor of a MEMS gyroscope based on Joule effect dynamic control for the first time to the knowledge of the authors, which adjusts the dissipation energy of a resistive element connected to the mechanical structure with closed loop control by monitoring the driving voltage. The results show that the relative variation of the Q-factor dramatically reduced by more than 30000× down to ∼120ppm from -40 to +60 after applying the proposed means to a dual-axis gyroscope, which achieves only 30ppm of driving voltage stability over 100 range with 3600× reduction. This technique is promising for enhancing the anti-shock performance and alleviating the bias thermal drift caused by the electrical coupling of the MEMS gyroscopes. © 2023 IEEE.

关键词： Thermodynamic stability

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Observation of diverse soliton patterns in an all-PM linear fiber laser mode-locked by NPE

Observation of diverse soliton patterns in an all-PM linear ...

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2024 Advanced Fiber Laser Conference, AFL 2024

作者： Zhou, Yuanzhu Sun, Yuqi Song, Yi Hou, Yuezhang Yu, Xuanyi Pan, Denian Yang, Yanji Yin, Jiahui Li, Zhili Deng, Chunjian Pan, Xinjian Wang, Tianshu Zhongshan Branch of State Key Laboratory of Electronic Thin Films and Integrated Devices College of Electronic and Information University of Electronic Science and Technology of China Zhongshan Institute Zhongshan528402 China National and Local Joint Engineering Research Center of Space Optoelectronics Technology Changchun University of Science and Technology Changchun130022 China

ISBN: (数字)9781510688889

ISBN: (纸本)9781510688872

We have investigated a stable and flexible all-polarization-maintaining (PM) linear fiber laser mode-locked by nonlinear polarization evolution (NPE). The pulse states are investigated for different net intracavity dispersion values ranging from negative to positive by varying the grating pair distance. A spectral bandwidth of 39.8 nm was obtained with a pulse duration of 1.89 ps at a repetition rate of 147.0 MHz, which can be further compressed to 66 fs. Meanwhile, we have observed harmonic mode-locked solitons and bound state solitons in this linear fiber laser. The second- and third-order harmonic mode-locking were observed with repetition rates of 294.1 MHz and 442.3 MHz. The soliton number inside the bound states decreases from 4 solitons to 1 soliton by reducing the pump power. The results of experiment fully demonstrate that the all-PM NPE mode-locked fiber laser is an ideal platform for investigating soliton dynamics and ultrashort pulses. © 2025 SPIE.

关键词： Mode-locked fiber lasers

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Fe/BC co-conditioners with environmental and economic benefits on composting:reduced NH_(3)emissions and improved fertilizer quality

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Biochar 2024年第1期6卷 50-65页

作者： Jixiang Wang Huifang Xie Jun Wu Weijiang He Xi Zhang Junxia Huang Yanfang Feng Lihong Xue Key Laboratory of Agro-Environment in Downstream of Yangtze Plain Ministry of Agriculture and Rural AffairsInstitute of Agricultural Resources and EnvironmentJiangsu Academy of Agricultural SciencesNanjing 210014China. Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse School of Environmental and Biological EngineeringNanjing University of Science and TechnologyNanjing 210094China. Key Laboratory of Integrated Regulation and Resources Development of Shallow Lakes Ministry of EducationCollege of EnvironmentHohai UniversityNanjing 210098China.

The significant volatilization of NH_(3)during aerobic composting causes nitrogen(N)losses and environmental *** iron(Fe)and biochar(BC)can influence the N conversion process in *** application can delay the maturation of materials,while biochar can enhance the quality of organic *** combination of these two conditioners may help decrease NH_(3)emissions and improve organic fertilizer ***,this study investigates the effects of different doses of FeCl_(3)and BC on NH_(3)emissions and organic fertilizer quality during *** results demonstrated that Fe/BC co-conditioners reduced the accumulation of NH_(3)emissions during composting by 11.1-48.2%,increased the total nutrient content by 0.6-15.3%,and enhanced economic and environmental benefits by 0.1-23.6$t^(−1).At the high-temperature stage of composting,Fe/BC co-conditioners decreased the pH by 0.3-1.2,but there was no significant difference compared to the control at the end of composting,and they did not affect compost *** structural equation model analysis suggested that the reduction in NH_(3)emis-sions was related to ammonia-oxidizing bacteria(AOB),NH_(4)^(+)-N,and total nitrogen(TN).As a result,the Fe/BC co-conditioners reduced NH_(3)emissions by lowering the pH at the beginning of composting and increasing the content of NH_(4)^(+)-*** study concludes that Fe/BC co-conditioners could complement each other to significantly reduce NH_(3)emissions and improve the quality of organic fertilizers.

关键词： Aerobic composting Biochar Organic fertilizer NH_(3)emissions FeCl_(3)

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Multivariate Multiscale Sample Entropy for Multi-Channel Underwater Acoustic Signal Analysis 7

Multivariate Multiscale Sample Entropy for Multi-Channel Und...

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7th IEEE Information technology, Networking, Electronic and Automation control Conference, ITNEC 2024

作者： Zhou, Jing Li, Yaan Wang, Mingzhou Shi, Lei School of Marine Science and Technology Northwestern Polytechnical University Xi'an China Xi'an Precision Machinery Research Institute National Key Laboratory of Underwater Information and Control Xi'an China

ISBN: (纸本)9798350370782

Multi-channel time series collected by arrays are prevalent in underwater acoustic signal processing and are crucial for uncovering the intrinsic characteristics of the observed system. This paper introduces the multivariate multiscale sample entropy (MMSE) to assess the complexity information in multi-channel underwater acoustic signals. Simulation analysis is employed to validate the effectiveness of the MMSE algorithm in extracting both within-channel and cross-channel information from multi-channel signals. Various types of simulated ship-radiated noise are generated to illustrate the MMSE algorithm's capability to differentiate between signals. Additionally, we employ MMSE to analyze various real-world signals, including ship-radiated noise, ambient noise, and interface reverberation. The MMSE results demonstrate its proficiency in differentiating various underwater acoustic signals compared to traditional frequency domain methods. © 2024 IEEE.

关键词： Frequency domain analysis

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Impact of Evaporation Duct on Electromagnetic Wave Propagation During a Typhoon

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Journal of Ocean University of China 2022年第5期21卷 1069-1083页

作者： WANG Shuwen YANG Kunde SHI Yang YANG Fan ZHANG Hao School of Marine Science and Technology Northwestern Polytechnical UniversityXi’an 710072China Key Laboratory of Ocean Acoustics and Sensing Northwestern Polytechnical UniversityMinistry of Industry and Information TechnologyXi’an 710072China National Key Laboratory of Underwater Information Processing and Control Xi’an 710072China

The evaporation duct,a result of evaporation from the ocean,is a region above the sea surface in which radio waves are refracted *** duct has strong effects on microwave *** cause huge anomalies in marine meteorological parameters that influence the evaporation duct distribution and structure,which in turn affects the propagation of electromagnetic(EM)***,EM wave propagation under the typhoon process has seldom been ***,taking Typhoon Phanfone(201929)as an example,this study uses a dataset from the European Centre for Medium-Range Weather Forecasts,combined with the Naval Atmospheric Vertical Surface Layer Model and the parabolic equation model,to study the evaporation duct’s impact on EM wave propagation during a *** spatial and temporal path loss distributions reveal that large amounts of EM wave energy are emitted from the evaporation duct when the EM wave passes through a typhoon *** average,a typhoon eye causes an approximately 20 dB increase in path loss for EM wave propagation at low antenna ***,the effects of a typhoon eye on EM wave propagation at different signal frequencies and antenna heights are *** results show that a typhoon has a larger impact on EM wave propagation with low signal frequency and high antenna height.

关键词： evaporation duct typhoon ECMWF wave glider electromagnetic wave propagation

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Strigolactone-gibberellin crosstalk mediated by a distant silencer fine-tunes plant height in upland cotton

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Molecular Plant 2024年第10期17卷 1539-1557页

作者： Zailong Tian Baojun Chen Hongge Li Xinxin Pei Yaru Sun Gaofei Sun Zhaoe Pan Panhong Dai Xu Gao Xiaoli Geng Zhen Peng Yinhua Jia Daowu Hu Liru Wang Baoyin Pang Ai Zhang Xiongming Du Shoupu He State Key Laboratory of Cotton Bio-breeding and Integrated Utilization Institute of Cotton ResearchChinese Academy of Agricultural SciencesAnyangChina Zhengzhou Research Base State Key Laboratory of Cotton Bio-breeding and Integrated UtilizationSchool of Agricultural SciencesZhengzhou UniversityZhengzhouChina National Nanfan Research Institute(Sanya) Chinese Academy of Agricultural SciencesSanyaHainanChina School of Computer Science&Information Engineering Anyang Institute of TechnologyAnyangChina National Supercomputing Center in Zhengzhou Zhengzhou UniversityZhengzhouChina

Optimal plant height is crucial in modern agriculture, influencing lodging resistance and facilitating mechanized crop production. Upland cotton (Gossypium hirsutum) is the most important fiber crop globally;however, the genetic basis underlying plant height remains largely unexplored. In this study, we conducted a genome-wide association study to identify a major locus controlling plant height (PH1) in upland cotton. This locus encodes gibberellin 2-oxidase 1A (GhPH1) and features a 1133-bp structural variation (PAVPH1) located approximately 16 kb upstream. The presence or absence of PAVPH1 influences the expression of GhPH1, thereby affecting plant height. Further analysis revealed that a gibberellin-regulating transcription factor (GhGARF) recognizes and binds to a specific CATTTG motif in both the GhPH1 promoter and PAVPH1. This interaction downregulates GhPH1, indicating that PAVPH1 functions as a distant upstream silencer. Intriguingly, we found that DWARF53 (D53), a key repressor of the strigolactone (SL) signaling pathway, directly interacts with GhGARF to inhibit its binding to targets. Moreover, we identified a previously unrecognized gibberellin-SL crosstalk mechanism mediated by the GhD53-GhGARF-GhPH1/PAVPH1 module, which is crucial for regulating plant height in upland cotton. These findings shed light on the genetic basis and gene interaction network underlying plant height, providing valuable insights for the development of semi-dwarf cotton varieties through precise modulation of GhPH1 expression.

关键词： plant height gibberellin 2-oxidase 1A silencer phytohormone crosstalk

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A master-slave generalized predictive synchronization control for preheating process of multi-cavity hot runner system

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Chinese Journal of Chemical Engineering 2023年第10期62卷 270-280页

作者： Hongyi Qu Shengyong Mo Ke Yao Zhao-Xia Huang Zhihao Xu Furong Gao Institute of Intelligent Manufacturing Guangdong Academy of SciencesGuangdong Key Laboratory of Modern Control TechnologyGuangzhou 510070China Fok Ying Tung Graduate School The Hong Kong University of Science and TechnologyGuangzhou 511442China Department of Chemical and Biological Engineering The Hong Kong University of Science and TechnologyHong Kong 999077China National Engineering Research Center of Novel Equipment for Polymer Processing Department of Mechanical and Automotive EngineeringSouth China University of TechnologyGuangzhou 510641China

As a key component of injection molding,multi-cavity hot runner(MCHR)system faces the crucial problem of polymer melt filling imbalance among the *** thermal imbalance in the system has been considered as the leading ***,the solution may rest with the synchronization of those heating processes in MCHR *** paper proposes a’Master-Slave’generalized predictive synchronization control(MS-GPSC)method with’***’strategy for preheating stage of MCHR *** core of the proposed method is choosing the heating process with slowest dynamics as the’Master’to track the setpoint,while the other heating processes are treated as‘Slaves’tracking the output of’Master’.This proposed method is shown to have the good ability of temperature *** corresponding analysis is conducted on parameters tuning and stability,simulations and experiments show the strategy is effective.

关键词： Process control Thermodynamics process Model-predictive control Multi-cavity hot runner system Master-Slave synchronization Mr.Slowest

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Experimental realization of multi-mode pulse generation in a circular Yb-doped Mamyshev laser at 1030nm

Experimental realization of multi-mode pulse generation in a...

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2024 Advanced Fiber Laser Conference, AFL 2024

作者： Sun, Yuqi Duan, Yunfei Zhou, Yuanzhu Hou, Yuezhang Gu, Xiaoyi Zheng, Jiamin Yin, Jiahui Lin, Xiang Dong, Zhiliang Deng, Chunjian Pan, Xinjian Wang, Tianshu National and Local Joint Engineering Research Center of Space Optoelectronics Technology Changchun University of Science and Technology Changchun130022 China Zhongshan Branch of State Key Laboratory of Electronic Thin Films and Integrated Devices College of Electronic and Information University of Electronic Science and Technology of China Zhongshan Institute Zhongshan528402 China

ISBN: (数字)9781510688889

ISBN: (纸本)9781510688872

We report a Mamyshev laser with mode-locking by seed injection. The laser produced a single pulse with a repetition frequency of 12.1 MHz, obtaining an optimal output spectrum of 41.6 nm. The output pulse width was 6.7 ps, compressed to 44 fs, and the output power reached 830 mW. Stability tests showed an RMS of less than 0.6 %, demonstrating good stability. In addition, bound-state solitons and harmonic mode-locking phenomena were observed in the experiments, and double-pulse, quadruple-pulse and quintuple-pulse bound-state solitons and 2nd-4th harmonic mode-locking were successfully obtained. The compressed pulse widths are all less than 100 fs. © 2025 SPIE.

关键词： Fiber lasers

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Strain engineering of Pt-based electrocatalysts for oxygen reaction reduction

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Frontiers in Energy 2024年第2期18卷 241-262页

作者： Zeyu WANG Yanru LIU Shun CHEN Yun ZHENG Xiaogang FU Yan ZHANG Wanglei WANG State Key Laboratory of Solidification Processing Atomic Control and Catalysis Engineering LaboratorySchool of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072China State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration National Clinical Research Center for Oral DiseasesShaanxi Key Laboratory of StomatologyDepartment of Dental MaterialsSchool of StomatologyThe Fourth Military Medical UniversityXi’an 710032China Institute of New Energy Materials and Engineering School of Materials Science and EngineeringFuzhou UniversityFuzhou 350108China Key Laboratory of Marine Chemistry Theory and Technology(Ministry of Education) College of Chemistry and Chemical EngineeringOcean University of ChinaQingdao 266100China

Proton exchange membrane fuel cells(PEMFCs)are playing irreplaceable roles in the construction of the future sustainable energy ***,the insufficient performance of platinum(Pt)-based electrocatalysts for oxygen reduction reaction(ORR)hinders the overall efficiency of *** the surface strain of catalysts is considered an effective way to tune their electronic structures and therefore optimize catalytic *** this paper,insights into strain engineering for improving Pt-based catalysts toward ORR are elaborated in ***,recent advances in understanding the strain effects on ORR catalysts are comprehensively ***,strain engineering methodologies for adjusting Ptbased catalysts are comprehensively ***,further information on the various challenges and potential prospects for strain modulation of Pt-based catalysts is provided.

关键词： strain engineering Pt-based catalysts oxygen reduction reaction(ORR) catalytic performance proton exchange membrane fuel cells(PEMFCs)

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