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Trimethylamine oxide supplementation differentially regulates fat deposition in liver,longissimus dorsi muscle and adipose tissue of growing-finishing pigs

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Animal Nutrition 2024年第2期17卷 25-35页

作者： Andong Zha Wanquan Li Jing Wang Ping Bai Ming Qi Peng Liao Bie Tan Yulong Yin Laboratory of Animal Nutritional Physiology and Metabolic Process Key Laboratory of Agro-ecological Processes in Subtropical RegionNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry ProductionInstitute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125China College of Animal Science and Technology Hunan Agricultural UniversityChangsha 410128China University of Chinese Academy of Sciences Beijing 100008China Yunnan Southwest Agriculture and Animal Husbandry Group Co. Ltd.Kunming 650224China

Trimethylamine oxide(TMAO)is a microbiota-derived metabolite,and numerous studies have shown that it could regulate fat metabolism in humans and ***,few studies have focused on the effects of TMAO on fat deposition in growing-finishing *** study aimed to investigate the effect of TMAO on fat deposition and intestinal microbiota in growing-finishing *** growing pigs were randomly divided into 2 groups and fed with a basal diet with 0 or 1 g/kg TMAO for 149 *** intestinal microbial profiles,fat deposition indexes,and fatty acid profiles were *** results showed that TMAO supplementation had a tendency to decrease lean body mass(P<0.10)and significantly increased backfat thickness(P<0.05),but it did not affect growth *** significantly increased total protein(TP)concentration,and reduced alkaline phosphatase(ALP)concentration in serum(P<0.05).TMAO increased the α diversity of the ileal microbiota community(P<0.05),and it did not affect the colonic microbial *** supplementation significantly increased acetate content in the ileum,and Proteobacteria and Escherichia-Shigella were significantly enriched in the TMAO group(P<0.05).In addition,TMAO decreased fat content,as well as the ratio of linoleic acid,n-6 polyunsaturated fatty acids(PUFA),and PUFA in the liver(P<0.05).On the contrary,TMAO increased intramuscular fat content of the longissimus dorsi muscle,whereas the C18:2n6c ratio was increased,and the n-6 PUFA:PUFA ratio was decreased(P<0.05).In vitro,1 mmol/LTMAO treatment significantly upregulated the expression of FASN and SREBP1 in C2C12 cells(P<0.05).Nevertheless,TMAO also increased adipocyte area and decreased the CPT-1B expression in subcutaneous fat(P<0.05).Taken together,TMAO supplementation regulated ileal microbial composition and acetate production,and regulated fat distribution and fatty acid composition in growing-finishing *** results provide new insights for understanding the role of TMA

关键词： Growing-finishing pig Trimethylamine oxide Fat deposition Fatty acid composition Intestinal microbiota

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Investigation of Reusable Launch Vehicle Landing Guidance control with Multiple Sliding Surface Technique

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Journal of Beijing Institute of technology (English Edition) 2021年第zk期30卷 151-158页

作者： Teng, Xin Lin, Defu Xiao, Long Zhang, Fengdi Beijing Aerospace Automatic Control Institute Beijing100854 China Beijing Institute of Technology Beijing100081 China National Key Laboratory of Science and Technology on Aerospace Intelligence Control Beijing100854 China

This paper proposes an autonomous approach and landing guidance law for a reusable launch vehicle (RLV) at the specified runway touchdown. With the full nonlinear point-mass dynamics, the multiple sliding surfaces guidance (MSSG) technique is developed for the closed-loop guidance law to guarantee a successful approach and landing (A&L) movement, which has the same advantage in the finite time convergent property as higher order sliding mode control. Its global stability is proved using Lyapunov theory. The resultant guidance law has features in on-line trajectories calculation without any off-line analysis only using the boundary conditions of the A&L phase and instantaneous states of the RLV. Therefore, it is capable of targeting different touchdown points on the runway and overcoming large initial condition errors. Simulations are provided to verify the effectiveness of the proposed law. © 2020 Journal of Beijing Institute of technology

关键词： Sliding mode control

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Addition Al and/or Ti Induced Modifi cations of Microstructures, Mechanical Properties, and Corrosion Properties in CoCrFeNi High-Entropy Alloy Coatings

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Acta Metallurgica Sinica(English Letters) 2021年第8期34卷 1087-1102页

作者： Guoliang Ma Yong Zhao Hongzhi Cui Xiaojie Song Mingliang Wang Kwangmin Lee Xiaohua Gao Qiang Song Canming Wang School of Materials Science and Engineering Shandong University of Science and TechnologyQingdao 266590China Key Laboratory of Solidifi cation Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China School of Materials Science and Engineering Chonnam National UniversityGwangju 61186Korea

The purpose of this work is to study the influences of Al and/or Ti addition on the microstructures, mechanical properties and corrosion properties of CoCrFeNi-(Al, Ti) high entropy alloy(HEA) coatings. Three coatings, AlCoCrFeNi(Ⅰ), CoCrFeNiTi_(0.5)(Ⅱ) and AlCoCrFeNiTi_(0.5)(Ⅲ), were fabricated by laser cladding successfully. The AlCoCrFeNi(Ⅰ) coating exhibited a simple body-centered cubic(BCC) solid-solution structure, whereas the CoCrFeNiTi_(0.5)(Ⅱ) alloy exhibited a face-centered cubic(FCC) solid-solution and a small amount of Laves phase. The BCC phases in AlCoCrFeNiTi _(0.5)(Ⅲ) coating were characterized as Fe–Cr rich disordered BCC phases(A2) and Al-Ni–Ti-rich ordered BCC phases(L2_1) separately. The AlCoCrFeNiTi_(0.5)(Ⅲ) coating with dual-phase BCC structure showed the optimal performance of both mechanical and corrosion properties, which was superior to BCC-based AlCoCrFeNi(Ⅰ) and FCC-based CoCrFeNiTi_(0.5)(Ⅱ) coatings. Nanoindentation tests and quantitative investigations on the strengthening mechanisms of AlCoCrFeNiTi_(0.5)(Ⅲ) coating were conducted, suggesting that the precipitation strengthening is the dominant strengthening mechanism. In short, the addition of moderate amount of Al and Ti in CoCrFeNi HEA shows potential for the development of a high strength and corrosion-resistant coating.

关键词： High entropy alloy Laser cladding Corrosion properties Mechanical properties

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Regulating microstructure and composition by carbonizing in-situ grown metal-organic frameworks on cotton fabrics for boosting electromagnetic wave absorption

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Nano Research 2024年第8期17卷 7290-7300页

作者： Jie Jin Hongsen Long Hu Liu Yan Guo Tiantian Bai Ben Bin Xu Mohammed A.Amin Hua Qiu Mohamed H.Helal Chuntai Liu Changyu Shen Zeinhom M.El-Bahy Zhanhu Guo State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentNational Engineering Research Center for Advanced Polymer Processing TechnologyZhengzhou UniversityZhengzhou 450002China China State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410000China School of Electronic Engineering North China University of Water Resources and Electric PowerZhengzhou 450046China Complex Conditions of High-end Tire Technology Innovation Center Shuguang Rubber Industry Research&Design Institute Co.LtdGuilin 541004China Integrated Composites Lab Department of Mechanical and Civil EngineeringNorthumbria UniversityNewcastle Upon TyneNE18STUK Department of Chemistry College of ScienceTaif UniversityP.O.Box 11099Taif 21944Saudi Arabia Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Department of Chemistry Faculty of Arts and ScienceNorthern Border UniversityRafha 73213Saudi Arabia Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr City 11884CairoEgypt

High-temperature carbonized metal-organic frameworks(MOFs)derivatives have demonstrated their superiority for promising electromagnetic wave(EMW)absorbers,but they still suffer from limited EMW absorption capacity and narrow *** the advantage of microstructure and chemical composition regulation for the design of EMW absorber,hierarchical heterostructured MoS_(2)/CoS_(2)-Co_(3)O_(4)@cabonized cotton fabric(CF)(MCC@CCF)is prepared by growing ZIF-67 MOFs onto CF surface,chemical etching,and *** from the dual loss mechanism of magnetic-dielectric multicomponent carbonized MOFs,chemical etching and carbonization process can effectively introduce abundant micro-gap structure that can result in better impedance matching and stronger absorption capacity via internal reflection,doped heteroatoms(Mo,N,S)to supply additional dipolar polarization loss,and numerous heterointerfaces among MoS_(2),CoS_(2),Co_(3)O_(4),and CCF that produce promoted conduction loss and interfacial polarization ***,a minimal reflection loss of−52.87 dB and a broadest effective absorption bandwidth of 6.88 GHz were achieved via tunning the sample thickness and filler loading,showing excellent EMW absorption *** research is of great value for guiding the research on MOFs derivatives based EMW absorbing materials.

关键词： metal-organic frameworks hierarchical structure chemical etching sulfurization electromagnetic wave absorption

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Decouple the intermolecular interaction by encapsulating an insulating sheath

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Chinese Chemical Letters 2025年第06期 527-531页

作者： Saisai Yuan Yiming Chen Xijuan Wang Degui Zhao Tengyang Gao Caiyun Wei Chuanxiang Chen Yang Yang Wenjing Hong School of Environmental and Chemical Engineering Jiangsu University of Science and Technology National&Local Joint Engineering Research Center for Mineral Salt Deep Utilization Huaiyin Institute of Technology Key Laboratory of Organic Compound Pollution Control Engineering (MOE) School of Environmental and Chemical EngineeringShanghai University College of Chemical Engineering&College of Materials Science and Engineering Fuzhou University State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical Engineering&Pen-Tung Institute of Micro-Nano Science and TechnologyXiamen University

Single-molecule junctions are building blocks for constructing molecular devices. However, intermolecular interactions like winding bring additional interference among the surrounding molecules, which inhibits the intrinsic coherent transport through single-molecule junctions. Here, we employed a nanocavity(dimethoxypillar[5]arene, DMP[5]), which is analogous to electric cables, to confine the conformation of flexible chains(1,8-diaminooctane, DAO) via host-guest interaction. Single-molecule conductance measurements indicate that the conductance of DAO encapsulated with DMP[5] is as high as that of pure DAO, as reproduced by theoretical simulations. Intriguingly, the molecular lengths of the DAO encapsulated with DMP[5] increase from 1.13 nm to 1.46 nm compared with the pure DAO, indicating that DMP[5]keeps DAO upright-standing via the confinement effect. This work provides a new strategy to decouple the intermolecular interaction by employing an insulating sheath, enabling the high-density integration of single-molecule devices.

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Imaging Detection and Classification for Near-space Dim Targets 7

Imaging Detection and Classification for Near-space Dim Targ...

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7th International Conference on Vision, Image and Signal Processing, ICVISP 2023

作者： Yuan, Yupu Xi, Runping Chen, Qian School of Computer Science Northwestern Polytechnical University Xi'an China Shaanxi Province Key Laboratory of Speech & Image Processing Xi'an China National Engineering Laboratory of Integrated Aero-Space-Ground-Ocean Big Data Application Technology Xi'an China

ISBN: (纸本)9781839539848

The motion mode of near-space targets is complex due to their high threat level. The target imaging faces low SNR and susceptibility to background noise. The existing detection and classification algorithms struggle to meet the demands of performance and speed on such targets. To address these issues, a YOLOv5-based target detection algorithm utilizes CARAFE upsampling and the small detection head to extract internal features and edge information of dim target. The algorithm adeptly captures dim target features, enhancing real-time performance and detection accuracy while overcoming subtle feature granularity and extraction difficulties. Aiming at the problem that there is no existing trajectory classification algorithm in the near-space field, we propose an infrared dim target trajectory classification algorithm. The improved attention module is used to enhance the extraction of motion features, and the target category is accurately identified by the prediction module, improving the capacity to extract dependencies between trajectory fragments. We execute comparative experiments on common infrared dim target dataset, near-space infrared dim target dataset and real dataset to confirm the viability of our methods. The outcomes indicate that our proposed method can be applied to the above three types of dim targets and significantly outperforms state-of-the-art methods. © The Institution of Engineering & technology 2023.

关键词： Extraction

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Infrared Fuzzy Video Data Cleaning Based on Improved YOLOv5 11th

Infrared Fuzzy Video Data Cleaning Based on Improved YOLOv5

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11th China Conference on Command and control, C2 2023

作者： Gong, Hua Tian, Haoyuan Chen, Congang Hu, Yutong School of Science Shenyang Ligong University Shenyang110159 China Liaoning Key Laboratory of Intelligent Optimization and Control for Ordnance Industry Shenyang110159 China Faculty of Science and Technology Beijing Normal University—Hong Kong Baptist University United International College Zhuhai519087 China National Key Laboratory of Electromagnetic Space Security Tianjing300308 China

ISBN: (纸本)9789819990207

Aiming at the problem that infrared fuzzy video data affect video quality, an improved YOLO v5 deep network model is established to carry out intelligent and accurate infrared fuzzy video data cleaning. Considering the problem of missing infrared fuzzy video data, a dataset named SYLU-INFRARED VIDEO DATASET is constructed. This dataset includes 5000 aerial and ground background infrared fuzzy video frames. Considering the spatiotemporal joint features of video data, a CBAM attention mechanism with two-dimensional attention allocation strategies is applied. This attention can automatically allocate the importance of video features extracted by YOLOv5 backbone in both spatial and channel dimensions. The experimental results show that the fusion model of CBAM and YOLO v5 enhances the cleaning effectiveness. CBAM-YOLOv5 has an increase of 17.8%, 28.4%, and 26.5% in Precision, Recall, and mAP compared to YOLOv7, respectively. © Chinese Institute of Command and control 2024.

关键词： Antennas

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Permafrost‒vegetation controls on water availability over the Qinghai‒Tibet Plateau

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Advances in Climate Change Research 2025年第3期16卷 526-537页

作者： Ji, Fang Fan, Lin-Feng Yuan, Shan-Shui Kuang, Xing-Xing Zhu, Liu-Jun Jin, Jun-Liang Yao, Ying-Ying Zhang, Jian-Yun Zheng, Chun-Miao The National Key Laboratory of Water Disaster Prevention Hohai University Nanjing 210024 China Yangtze Institute for Conservation and Development Hohai University Nanjing 210024 China Key Laboratory of Mountain Hazards and Engineering Resilience Institute of Mountain Hazards and Environment Chinese Academy of Sciences Chengdu 610213 China Key Laboratory of Hydrologic-Cycle and Hydrodynamic-System of Ministry of Water Resources Hohai University Nanjing 210024 China State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control School of Environmental Science and Engineering Southern University of Science and Technology Shenzhen 518055 China Department of Earth and Environmental Science School of Human Settlements and Civil Engineering Xi'an Jiaotong University Xi'an 710049 China State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Nanjing Hydraulic Research Institute Nanjing 210029 China Eastern Institute for Advanced Study Eastern Institute of Technology Ningbo 315200 China

Permafrost degradation substantially affects water resources within the cryosphere. It is crucial to elucidate the dynamics of water availability influenced by both permafrost degradation and climate change to fully comprehend the water cycle in cold regions, such as the Qinghai‒Tibet Plateau (QTP). While existing studies have established the hydrological consequences of permafrost degradation through altered soil hydraulics and water storage capacity, the complex interplay between thawing permafrost and vegetation dynamics—particularly their synergistic regulation of precipitation partitioning and runoff generation through root-zone water accessibility—are poorly understood, creating critical knowledge gaps in predicting long-term water availability trajectories. In this study, we explore the influence of permafrost-vegetation interactions on regional water availability on the QTP by integrating the effects of permafrost degradation on vegetation into the Budyko-Fu model. Our results reveal a consistent increase in surface runoff (R) of the permafrost regions from 1981 to 2100, predominantly driven by rising precipitation. However, shifts in vegetation patterns, prompted by permafrost degradation, significantly modify hydrological partitioning, leading to non-monotonic variations in the runoff to precipitation ratio (R/P). Notably, early-stage permafrost thaw enhances vegetation growth and evapotranspiration, which results in a decrease in R/P. Conversely, deeper permafrost thaw (e.g., beyond the root zone of vegetation) can lead to vegetation degradation, which subsequently reduces evapotranspiration and consequently increasing the R/P ratio. These findings underscore the pivotal role of vegetation in regulating the hydrological cycle and affecting water availability in permafrost-affected regions. © 2025 The Authors

关键词： Climate change Permafrost degradation Qinghai‒Tibet Plateau Vegetation Water availability

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A fast positioning method of navigation receiver assisted by Doppler information

A fast positioning method of navigation receiver assisted by...

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第十四届中国卫星导航年会

作者： Yinyin Tang Junyong Lu Junhong Feng Kai Li National Key Laboratory of Science and Technology on Vessel Integrated Power System Naval University of Engineering

In order to shorten the time to first fix(TTFF) of the satellite receiver,a fast positioning method using both carrier and pseudo code observation is ***,use the Doppler information acquired by the carrier tracking loop to reduce the a priori time accuracy to 100 ***,use the code phase acquired by pseudo-code tracking loop,and use the five-state equation to solve the receiver *** this way,positioning can be achieved before frame synchronization and bit *** simulation and test results show that positioning can be achieved within 1 second through Beidou/GPS dual system in the global or BeiDou alone in the Asia-Pacific region,when the a priori position accuracy is less than 10 km and the a priori time accuracy is less than 2 hours.

关键词： Time to First Fix Navigation Receiver Fast Positioning Doppler Information Code Phase

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Robust Attitude controller Designation of Launch Vehicle under Actuator Failure Condition via Deep Reinforcement Learning Algorithm

Robust Attitude Controller Designation of Launch Vehicle und...

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第35届中国控制与决策会议

作者： Chenhui Jia Xiaodong Liu Zhaolei Wang Qinghai Gong Xu Huang National Key Laboratory of Science and Technology on Aerospace Intelligent Control Beijing Aerospace Automatic Control Institute

This paper focuses on the robust and adaptive attitude control algorithm of the launch vehicle under the condition of the thrust drop failure of the attitude control nozzle during the flight *** solve this problem,we build a three-channel end to end attitude controller with TD3(Twin-delayed Deep Deterministic Policy Gradient)reinforcement learning algorithm which performs outstanding on solving the problems of continuous action space reinforcement *** simulation results indicate that the attitude controller designed with the algorithm can automatically adapt to the thrust drop condition of the launch vehicle nozzle and quickly adjust the output of the actuator to correct the attitude control *** method shows strong adaptability and robustness to the fault conditions and can be used as a potential algorithm in solving the problem of controller reconfiguration under the fault conditions of the launch vehicle.

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