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Optimization considerations of electrical space engines

Naval Engineers Journal 1962年第N 4期v 74卷 p749-756页

作者： Granet, I. Guman, W.J. Irving Granet received his B.M.E. from The Cooper Union: his M.M.E. from Polytechnic Institute of Brooklyn: has taken Pre-Doctoral Studies at Polytechnic Institute of Brooklyn: and is a graduate of the Oak Ridge School of Reactor Technology. He has worked in Republic's Plasma Propulsion Laboratory on nuclear propulsion systems space radiators thermodynamic power cycle considerations for generating electric power and system design and operation for space propulsion. He was formerly Director of Staff Engineering Nuclear Energy Department of Foster Wheeler Corporation where he directed engineering design and analysis for complete nuclear plants. Mr. Granet has taught thermodynamics and heat transfer at the Polytechnic Institute of Brooklyn and at present is Adjunct Assistant Professor of Engineering and Physics at Long Island University. He has published over 50 articles in the fields of thermodynamics applied mechanics heat transfer and nuclear energy. He is a member of the American Society of Mechanical Engineers National Society of Professional Engineers Pi Tau Sigma and Sigma Xi. He is a licensed Professional Engineer in the State of New York. Mr. Granet is listed in the 1960 edition of American Men of Science and is a reviewer for the American Chemical Society's technical publications. William J. Guman received degrees of B. Aero. E. M. Aero E. from and has completed courses for Ph.D. Aero. E. at Rensselaer Polytechnic Institute. He joined Republic's PlasmA Propulsion Laboratory in 1959 and there is conducting theoretical and experimental studies on non-steady wave interactions and flow processes in plasma engine configurations. Mr. Guman was Assistant Professor at Rensselaer Polytechnic Institute lecturing on fluid mechanics aerodynamics performance and stability and conducting laboratory courses in experimental fluid dynamics and wind tunnel research. He also investigated flow induction and was head of Rensselaer's supersonic wind tunnel laboratory. At the present he is also an Adjunct Assistan

Electrically powered pulsed plasma pinch engine was proposed earlier (see Engineering Index 1961 p 1447 and 1448);present work considers pertinent overall system performance parameters, and describes experimental methods of obtaining direct measurements of thrust and propellant mass consumption unique to low thrust space propulsion device;knowledge of thrust, rate of propellant consumption and input power are necessary to complete optimization study in practice.

关键词： Rocket engines

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Smart radio environments

arXiv

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arXiv 2021年

作者： Gradoni, Gabriele Renzo, Marco Di Díaz-Rubio, Ana Tretyakov, Sergei A. Caloz, Christophe Gradoni, Gabriele Peng, Zhen Alu, Andrea Lerosey, Geoffroy Fink, Mathias Galdi, Vincenzo Cui, Tie Jun Frazier, Benjamin W. Anlage, Steven M. Salucci, Marco Massa, Andrea Cheng, Qiang Wang, Jinghe Jin, Shi Dardari, Davide Decarli, Nicoló Yurduseven, Okan Matthaiou, Michail Kenney, Mitchell Gordon, George Georgiou, Orestis Nguyen, Cam Ly Martini, Enrica Maci, Stefano Wakatsuchi, Hiroki Phang, Sendy School of Mathematical Sciences Department of Electrical and Electronic Engineering University of Nottingham Nottingham United Kingdom Laboratoire des Signaux et Systémes CNRS CentraleSupélec Université Paris-Saclay Gif-sur-Yvette Paris France Department of of Electronics and Nanoengineering Aalto University Espoo Finland META Research Group KU Leuven Belgium School of Mathematical Sciences Department of Electrical and Electronic Engineering University of Nottingham University Park NG72RD United Kingdom Department of Electrical and Computer Engineering University of Illinois at Urbana-Champaign IL United States Advanced Science Research Center City University of New York United States Greenerwave 6 rue Jean Calvin Paris75005 France Institut Langevin 1 rue Jussieu Paris75005 France Fields & Waves Lab Department of Engineering University of Sannio Benevento Italy State Key Laboratory of Millimeter Waves Southeast University Nanjing China Applied Physics Laboratory Johns Hopkins University LaurelMD20723 United States Department of Electrical and Computer Engineering Department of Physics Quantum Materials Center University of Maryland College ParkMD20742 United States Trento Italy Chengdu China Beijing China Institute of Electromagnetic Space State Key Laboratory of Millimeter Waves Southeast University Nanjing210096 China National Mobile Communications Research Laboratory Southeast University Nanjing China University of Bologna Bologna Italy Bologna Italy Centre for Wireless Innovation Institute of Electronics Communications and Information Technology Queen’s University Belfast Belfast United Kingdom Department of Electrical and Electronic Engineering University of Nottingham Nottingham United Kingdom Department of Electrical and Computer Engineering University of Cyprus Nicosia Cyprus Wireless System Laboratory Corporate Research & Development Center Toshiba Corporation Kawasaki Japan Department of Information Engineering an

This Roadmap takes the reader on a journey through the research in electromagnetic wave propagation control via reconfigurable intelligent surfaces. Meta-surface modelling and design methods are reviewed along with physical realisation techniques. Several wireless applications are discussed, including beam-forming, focusing, imaging, localisation, and sensing, some rooted in novel architectures for future mobile communications networks towards 6G. © 2021, CC BY.

关键词： Electromagnetic wave propagation

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Synergistic Glutathione Depletion and STING Activation to Potentiate Dendritic Cell Maturation and Cancer Vaccine Efficacy

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Angewandte Chemie 2024年第10期136卷

作者： Dr. Jianping Liu Dr. Ye Zhang Bowei Yang Dr. Yingbo Jia Prof. Rui-Tian Liu Dr. Lingwen Ding Prof. Zheyu Shen Prof. Xiaoyuan Chen Departments of Diagnostic Radiology Surgery Chemical and Biomolecular Engineering and Biomedical Engineering Yong Loo Lin School of Medicine and College of Design and Engineering National University of Singapore Singapore 119074 Singapore Nanomedicine Translational Research Program Yong Loo Lin School of Medicine National University of Singapore Singapore 117597 Singapore School of Biomedical Engineering Southern Medical of University Guangzhou Guangdong 510515 P. R. China CAS Key Laboratory of Nano-Bio Interface Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou Jiangsu 215123 P. R. China State Key Laboratory of Biochemical Engineering Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 P. R. China Department of Pathology Yong Loo Lin School of Medicine National University of Singapore Singapore 119074 Singapore Clinical Imaging Research Center Center for Translational Medicine Yong Loo Lin School of Medicine National University of Singapore Singapore 117599 Singapore Institute of Molecular and Cell Biology Agency for Science Technology and Research (A*STAR) 61 Biopolis Drive Proteos Singapore 138673 Singapore

Dendritic cell (DC) maturation and antigen presentation are key factors for successful vaccine-based cancer immunotherapy. This study developed manganese-based layered double hydroxide (Mn-LDH) nanoparticles as a self-adjuvanted vaccine carrier that not only promoted DC maturation through synergistically depleting endogenous glutathione (GSH) and activating STING signaling pathway, but also facilitated the delivery of model antigen ovalbumin (OVA) into lymph nodes and subsequent antigen presentation in DCs. Significant therapeutic-prophylactic efficacy of the OVA-loaded Mn-LDH (OVA/Mn-LDH) nanovaccine was determined by the tumor growth inhibition in the mice bearing B16-OVA tumor. Our results showed that the OVA/Mn-LDH nanoparticles could be a potent delivery system for cancer vaccine development without the need of adjuvant. Therefore, the combination of GSH exhaustion and STING pathway activation might be an advisable approach for promoting DC maturation and antigen presentation, finally improving cancer vaccine efficacy.

关键词： Antigen Delivery DC Maturation GSH Depletion ROS Upregulation STING Activation

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The Blood Compatibility Challenge

SSRN

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SSRN 2019年

作者： Jaffer, Iqbal H. Weitz, Jeffrey I. Brash, John L. Horbett, Thomas A. Latour, Robert A. Tengvall, Pentti Gorbet, Maud Sperling, Claudia Maitz, Manfred F. Siedlecki, Christopher A. Werner, Carsten Sefton, Michael V. Maitz, Manfred F. Martins, M. Cristina L Grabow, Niels Matschegewski, Claudia Huang, Nan Chaikof, Elliot L. Barbosa, Mário A. Werner, Carsten Thrombosis and Atherosclerosis Research Institute McMaster University 237 Barton Street East HamiltonONL8L 2X2 Canada McMaster University HamiltonON Canada University of Washington SeattleWA United States Clemson University ClemsonSC United States Gothenburg University Gothenburg Sweden Department of System Design Engineering University of Waterloo WaterlooON Canada Institute Biofunctional Polymer Materials Max Bergmann Center of Biomaterials Leibniz-Institut für Polymerforschung Dresden e.V. Dresden Germany Department of Surgery The Pennsylvania State University College of Medicine Hershey PA17033 United States Department of Bioengineering The Pennsylvania State University College of Medicine Hershey PA17033 United States University of Toronto Institute Biofunctional Polymer Materials Max Bergmann Center of Biomaterials Leibniz-Institut für Polymerforschung Dresden e.V. Dresden Germany i3S Instituto de Investigacao e Inovacao em Saude INEB Instituto de Engenharia Bionedica Rua Alfredo Allen 208 Porto4200-135 Portugal ICBAS Instituto de Ciencias Bioedicas Abel Salazar Universidade do Porto Porto Portugal Institut für Biomedizinische Technik Universitätsmedizin Rostock Friedrich-Barnewitz-Str. 4 Rostock18119 Germany Key Laboratory of Advanced Technology for Materials of Education Ministry School of Materials Science and Engineering Southwest Jiaotong University Chengdu610031 China Beth Israel Deaconess Medical Center Harvard Medical School 330 Brookline Avenue BostonMA02115 United States Wyss Institute for Biologically Inspired Engineering Harvard University 3 Blackfan Circle BostonMA02115 United States Harvard-MIT Division of Health Sciences and Technology 77 Massachusetts Avenue CambridgeMA02139 United States

Despite >50 years of study, there are no materials that are considered truly nonthrombogenic. Some materials minimize protein adsorption or cell adhesion while others actively inhibit thrombin generation through heparinization. Nonetheless the problem of biomaterial associated thrombogenicity remains. While once an active area of research, the problem has not only not been solved, it has also been largely abandoned. It is considered too hard or efforts attack only one particular aspect of the problem or more broadly new ideas and approaches have not been brought to bear. This frustration has led to a series of review papers where we summarize the features of broad agreement and provide commentary on those aspects of the problem that were subject to dispute. These are (see also Figure 1): 1. Blood-contacting medical devices: The scope of the problem;2. Protein adsorption phenomena governing blood reactivity;3. Material associated activation of blood cascades and cells;4. Surface modification for hemocompatible materials: passive and active approaches to guide blood-material interactions. We were inspired by the structure of the >1500 year old book of Jewish laws, called the Talmud, in which commentaries are layered on commentaries to interpret and reinterpret a biblical law. It takes the form of a record of discussions pertaining to Jewish law, ethics, philosophy, customs and history. Here we began with what we believed to be a generally accepted truth regarding thrombogenicity and then added our thoughts and commentaries regarding with respect to aspects that were not as scientifically firm as the opening "truth." We hope that future investigators will update these reviews as new scholarship resolves the uncertainties of today. © 2019, The Authors. All rights reserved.

关键词： Cell adhesion

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STUDIES OF A PLASMA PINCH SPACE ENGINE

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Journal of the American Society for Naval Engineers 1960年第4期72卷 715-725页

作者： GRANET, IRVING GUMAN, WILLIAM MCILROY, WILLIAM Irving Granet received his B.M.E. from The Cooper Union his M.M.E. from Polytechnic Institute of Brooklyn has taken Pre-Doctoral Studies at Polytechnic Institute of Brooklyn and is a graduate of the Oak Ridge School of Reactor Technology. He has worked in Republic's Plasma Propulsion Laboratory on nuclear propulsion systems space radiators thermodynamic power cycle considerations for generating electric power and system design and operation for space propulsion. He was formerly Director of Staff Engineering Nuclear Energy Department of Foster Wheeler Corporation where he directed engineering design and analysis for complete nuclear plants. Mr. Granet has taught thermodynamics and heat transfer at the Polytechnic Institute of Brooklyn and at present is Adjunct Assistant Professor of Engineering and Physics at Long Island University. He has published over 40 articles in the fields of thermodynamics applied mechanics heat transfer and nuclear energy. He is a member of the American Society of Mechanical Engineers National Society of Professional Engineers Pi Tau Sigma and Sigma Xi. He is a licensed Professional Engineer in the State of New York. Mr. Granet is listed in the 1960 edition of American Men of Science and is a reviewer for the American Chemical Society's technical publications. William J. Guman received degrees of B. Aero. E. M. Aero. E. from and has completed courses for Ph.D. Aero. E. at Rensselaer Polytechnic Institute. Since coming to Republic in 1959 Mr. Guman has been conducting theoretical and experimental studies on non-steady interactions and flow processes in plasma engine configurations. Mr. Guman was Assistant Professor at Rensselaer Polytechnic Institute lecturing on fluid mechanics aerodynamics performance and stability and conducting laboratory courses in experimental fluid dynamics and wind tunnel research. He also investigated flow induction and was head of Rensselaer's supersonic wind tunnel laboratory. Mr. Guman performed a theoretical analysis in experimental aerodynamic

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EXPERIMENTAL PROGRAM FOR A PLASMA PINCH SPACE ENGINE

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Journal of the American Society for Naval Engineers 1961年第4期73卷 745-761页

作者： GRANET, IRVING GUMAN, WILLIAM J. THE AUTHORS:Irving Granet received his B.M.E. from The Cooper Union his M.M.E. from Polytechnic Institute of Brooklyn has taken Pre-Doctoral Studies at Polytechnic Institute of Brooklyn and is a graduate of the Oak Ridge School of Reactor Technology. He has worked in Republic's Plasma Propulsion Laboratory on nuclear propulsion systems space radiators thermodynamic power cycle considerations for generating electric power and system design and operation for space propulsion. He was formerly Director of Staff Engineering Nuclear Energy Department of Foster Wheeler Corporation where he directed engineering design and analysis for complete nuclear plants. Mr. Granet has taught thermodynamics and heat transfer at the Polytechnic Institute of Brooklyn and at present is Adjunct Assistant Professor of Engineering and Physics at Long Island University. He has published over 40 articles in the fields of thermodynamics applied mechanics heat transfer and nuclear energy. He is a member of the American Society of Mechanical Engineers National Society of Professional Engineers Pi Tan Sigma and Sigma Xi. He is a licensed Professional Engineer in the State of New York. Mr. Granet is listed in the 1960 edition of American Men of Science and is a reviewer for the American Chemical Society's technical publications. William J. Guman received degrees of B. Aero. E. M. Aero E. from and has completed courses for PhD. Aero. E. at Rensselaer Polytechnic Institute. Since coming to Republic in 1959 Mr. Guman has been conducting theoretical and experimental studies on non-steady interactions and flow processes in plasma engine configurations. Mr. Guman was Assistant Professor at Rensselaer Polytechnic Institute lecturing on fluid mechanics aerodynamics performance and stability and conducting laboratory courses in experimental fluid dynamics and wind tunnel research. He also investigated flow induction and -was head of Rensselaer's supersonic wind tunnel laboratory. Mr. Guman performed a theoretical analysis in experimental

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ROLE OF SIMULATION IN RAPID PROTOTYPING FOR CONCEPT DEVELOPMENT

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NAVAL ENGINEERS JOURNAL 1991年第3期103卷 204-211页

作者： KING, JF BARTON, DE J. Fred King:is the manager of the Advanced Technology Department for Unisys in Reston Virginia. He earned his Ph.D. in mathematics from the University of Houston in 1977. He has been principal investigator of research projects in knowledge engineering pattern recognition and heuristic problem-solving. Efforts include the development of a multi-temporal multispectral classifier for identifying graincrops using LANDSAT satellite imagery data for NASA. Also as a member of the research team for a NCI study with Baylor College of Medicine and NASA he helped develop techniques for detection of carcinoma using multispectral microphotometer scans of lung tissue. He established and became technical director of the AI Laboratory for Ford Aerospace where he developed expert scheduling modeling and knowledge acquisition systems for NASA. Since joining Unisys in 1985 he has led the development of object-oriented programming environments blackboard architectures data fusion techniques using neural networks and intelligent data base systems. Douglas E. Barton:is manager of Logistics Information Systems for Unisys in Reston Virginia. He earned his B.A. degree in computer science from the College of William and Mary in 1978 and did postgraduate work in London as a Drapers Company scholar. Since joining Unisys in 1981 his work has concentrated on program management and software engineering of large scale data base management systems and design and implementation of knowledge-based systems in planning and logistics. As chairman of the Logistics Data Subcommittee of the National Security Industrial Association (NSIA) he led an industry initiative which examined concepts in knowledge-based systems in military logistics. His responsibilities also include evaluation development and tailoring of software engineering standards and procedures for data base and knowledge-based systems. He is currently program manager of the Navigation Information Management System which provides support to the Fleet Ballistic Missile Progr

A valuable technique during concept development is rapid prototyping of software for key design components. This approach is particularly useful when the optimum design approach is not readily apparent or several known alternatives need to be rapidly evaluated. A problem inherent in rapid prototyping is the lack of a "target system" with which to interface. Some alternatives are to develop test driver libraries, integrate the prototype with an existing working simulator, or build one for the specific problem. This paper presents a unique approach to concept development using rapid prototyping for concept development and scenario-based simulation for concept verification. The rapid prototyping environment, derived from artificial intelligence technology, is based on a blackboard architecture. The rapid prototype simulation capability is provided through an object-oriented modeling environment. It is shown how both simulation and blackboard technologies are used collectively to rapidly gain insight into a tenacious problem. A specific example will be discussed where this approach was used to evolve the logic of a mission controller for an autonomous underwater vehicle.

关键词： Military Engineering

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Author Correction: The FLUXNET2015 dataset and the ONEFlux processing pipeline for eddy covariance data

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Scientific data 2021年第1期8卷 72页

作者： Gilberto Pastorello Carlo Trotta Eleonora Canfora Housen Chu Danielle Christianson You-Wei Cheah Cristina Poindexter Jiquan Chen Abdelrahman Elbashandy Marty Humphrey Peter Isaac Diego Polidori Markus Reichstein Alessio Ribeca Catharine van Ingen Nicolas Vuichard Leiming Zhang Brian Amiro Christof Ammann M Altaf Arain Jonas Ardö Timothy Arkebauer Stefan K Arndt Nicola Arriga Marc Aubinet Mika Aurela Dennis Baldocchi Alan Barr Eric Beamesderfer Luca Belelli Marchesini Onil Bergeron Jason Beringer Christian Bernhofer Daniel Berveiller Dave Billesbach Thomas Andrew Black Peter D Blanken Gil Bohrer Julia Boike Paul V Bolstad Damien Bonal Jean-Marc Bonnefond David R Bowling Rosvel Bracho Jason Brodeur Christian Brümmer Nina Buchmann Benoit Burban Sean P Burns Pauline Buysse Peter Cale Mauro Cavagna Pierre Cellier Shiping Chen Isaac Chini Torben R Christensen James Cleverly Alessio Collalti Claudia Consalvo Bruce D Cook David Cook Carole Coursolle Edoardo Cremonese Peter S Curtis Ettore D'Andrea Humberto da Rocha Xiaoqin Dai Kenneth J Davis Bruno De Cinti Agnes de Grandcourt Anne De Ligne Raimundo C De Oliveira Nicolas Delpierre Ankur R Desai Carlos Marcelo Di Bella Paul di Tommasi Han Dolman Francisco Domingo Gang Dong Sabina Dore Pierpaolo Duce Eric Dufrêne Allison Dunn Jiří Dušek Derek Eamus Uwe Eichelmann Hatim Abdalla M ElKhidir Werner Eugster Cacilia M Ewenz Brent Ewers Daniela Famulari Silvano Fares Iris Feigenwinter Andrew Feitz Rasmus Fensholt Gianluca Filippa Marc Fischer John Frank Marta Galvagno Mana Gharun Damiano Gianelle Bert Gielen Beniamino Gioli Anatoly Gitelson Ignacio Goded Mathias Goeckede Allen H Goldstein Christopher M Gough Michael L Goulden Alexander Graf Anne Griebel Carsten Gruening Thomas Grünwald Albin Hammerle Shijie Han Xingguo Han Birger Ulf Hansen Chad Hanson Juha Hatakka Yongtao He Markus Hehn Bernard Heinesch Nina Hinko-Najera Lukas Hörtnagl Lindsay Hutley Andreas Ibrom Hiroki Ikawa Marcin Jackowicz-Korczynski Dalibor Janouš Wilma Jans Rachhpal Jassal Shicheng Jiang Tomomichi Kato Myr Computational Research Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA. gzpastorello@lbl.gov. DIBAF University of Tuscia Viterbo 01100 Italy. Euro-Mediterranean Centre on Climate Change Foundation (CMCC) Lecce 73100 Italy. Climate & Ecosystem Sciences Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA. Computational Research Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA. Department of Civil Engineering California State University Sacramento CA 95819 USA. Department of Geography Environment and Spatial Sciences Michigan State University East Lansing MI 48823 USA. Department of Computer Science University of Virginia Charlottesville VA 22904 USA. TERN Ecosystem Processes Menzies Creek VIC3159 Australia. Max Planck Institute for Biogeochemistry Jena 07701 Germany. Laboratoire des Sciences du Climat et de l'Environnement (LSCE) CEA CNRS UVSQ UPSACLAY Gif sur Yvette 91190 France. Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing 100101 China. Department of Soil Science University of Manitoba Winnipeg MB R3T2N2 Canada. Department of Agroecology and Environment Agroscope Research Institute Zürich 8046 Switzerland. School of Geography and Earth Sciences McMaster University L8S4K1 Hamilton ON Canada. Department of Physical Geography and Ecosystem Science Lund University Lund 22362 Sweden. Department of Agronomy and Horticulture University of Nebraska-Lincoln Lincoln NE 68583 USA. School of Ecosystem and Forest Sciences The University of Melbourne Richmond VIC3121 Australia. Department of Biology Research Group PLECO University of Antwerp Antwerp 2610 Belgium. Joint Research Centre European Commission Ispra 21027 Italy. TERRA Teaching and Research Center University of Liege Gembloux B-5030 Belgium. Finnish Meteorological Institute Helsinki 00560 Finland. ES

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids

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Nature 2023年第7965期618卷 E19-E20页

作者： Sarah E Graham Shoa L Clarke Kuan-Han H Wu Stavroula Kanoni Greg J M Zajac Shweta Ramdas Ida Surakka Ioanna Ntalla Sailaja Vedantam Thomas W Winkler Adam E Locke Eirini Marouli Mi Yeong Hwang Sohee Han Akira Narita Ananyo Choudhury Amy R Bentley Kenneth Ekoru Anurag Verma Bhavi Trivedi Hilary C Martin Karen A Hunt Qin Hui Derek Klarin Xiang Zhu Gudmar Thorleifsson Anna Helgadottir Daniel F Gudbjartsson Hilma Holm Isleifur Olafsson Masato Akiyama Saori Sakaue Chikashi Terao Masahiro Kanai Wei Zhou Ben M Brumpton Humaira Rasheed Sanni E Ruotsalainen Aki S Havulinna Yogasudha Veturi QiPing Feng Elisabeth A Rosenthal Todd Lingren Jennifer Allen Pacheco Sarah A Pendergrass Jeffrey Haessler Franco Giulianini Yuki Bradford Jason E Miller Archie Campbell Kuang Lin Iona Y Millwood George Hindy Asif Rasheed Jessica D Faul Wei Zhao David R Weir Constance Turman Hongyan Huang Mariaelisa Graff Anubha Mahajan Michael R Brown Weihua Zhang Ketian Yu Ellen M Schmidt Anita Pandit Stefan Gustafsson Xianyong Yin Jian'an Luan Jing-Hua Zhao Fumihiko Matsuda Hye-Mi Jang Kyungheon Yoon Carolina Medina-Gomez Achilleas Pitsillides Jouke Jan Hottenga Gonneke Willemsen Andrew R Wood Yingji Ji Zishan Gao Simon Haworth Ruth E Mitchell Jin Fang Chai Mette Aadahl Jie Yao Ani Manichaikul Helen R Warren Julia Ramirez Jette Bork-Jensen Line L Kårhus Anuj Goel Maria Sabater-Lleal Raymond Noordam Carlo Sidore Edoardo Fiorillo Aaron F McDaid Pedro Marques-Vidal Matthias Wielscher Stella Trompet Naveed Sattar Line T Møllehave Betina H Thuesen Matthias Munz Lingyao Zeng Jianfeng Huang Bin Yang Alaitz Poveda Azra Kurbasic Claudia Lamina Lukas Forer Markus Scholz Tessel E Galesloot Jonathan P Bradfield E Warwick Daw Joseph M Zmuda Jonathan S Mitchell Christian Fuchsberger Henry Christensen Jennifer A Brody Mary F Feitosa Mary K Wojczynski Michael Preuss Massimo Mangino Paraskevi Christofidou Niek Verweij Jan W Benjamins Jorgen Engmann Rachel L Kember Roderick C Slieker Ken Sin Lo Nuno R Zilhao Phuong Le Marcus E Kleber Graciela E Delgado Shaofeng Huo Dai Department of Internal Medicine Division of Cardiology University of Michigan Ann Arbor MI USA. VA Palo Alto Health Care System Palo Alto CA USA. Department of Medicine Division of Cardiovascular Medicine Stanford University School of Medicine Stanford CA USA. Department of Computational Medicine and Bioinformatics University of Michigan Ann Arbor MI USA. William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK. Department of Biostatistics and Center for Statistics Genetics University of Michigan Ann Arbor MI USA. Department of Genetics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Clinical Pharmacology William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK. Endocrinology Boston Children's Hospital Boston MA USA. Medical and Population Genetics Broad Institute Cambridge MA USA. Department of Genetic Epidemiology University of Regensburg Regensburg Germany. McDonnell Genome Institute and Department of Medicine Washington University St Louis MO USA. Department of Precision Medicine Division of Genome Science National Institute of Health Cheongju-si South Korea. Tohoku Medical Megabank Organization Tohoku University Sendai Japan. Sydney Brenner Institute for Molecular Bioscience Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa. Center for Research on Genomics and Global Health National Human Genome Research Institute National Institutes of Health Bethesda MD USA. Blizard Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK. Wellcome Sanger Institute Hinxton UK. Department of Epidemiology Emory University Rollins School of Public Health Atlanta GA USA. Atlanta VA Health Care System Decatur GA USA. Malcolm Randall VA Medical Center Gainesville FL USA. Division of Vascular Sur

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