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arXiv 2024年

作者： Smith, Lucas D. Cannady, Nicholas Caputo, Regina Kierans, Carolyn Kirschner, Nicholas Liceaga-Indart, Iker McEnery, Julie Metzler, Zachary Moiseev, A.A. Parker, Lucas Perkins, Jeremy Sasaki, Makoto Schoenwald, Adam J. Shy, Daniel Valverde, Janeth Wasti, Sambid Woolf, Richard Bolotnikov, Aleksey Caligiure, Thomas J. Crosier, A. Wilder Fried, Jack Ghosh, Priyarshini Griffin, Sean Grove, J. Eric Hays, Elizabeth Kong, Emily Mitchell, John Phlips, Bernard Sleator, Clio Thompson, D.J. Wulf, Eric Zajczyk, Anna University of Maryland College ParkMD20742 United States NASA Goddard Space Flight Center GreenbeltMD20771 United States University of Maryland Baltimore County BaltimoreMD21250 United States Center for Research and Exploration in Space Science and Technology GreenbeltMD20771 United States George Washington University WashingtonDC20052 United States Los Alamos National Laboratory Los AlamosNM87545 United States U.S. Naval Research Laboratory WashingtonDC20375 United States Catholic University of America WashingtonDC20064 United States Brookhaven National Laboratory UptonNY11973 United States Naval Research Enterprise Internship Program U.S. Naval Research Laboratory WashingtonDC20375 United States Wisconsin IceCube Particle Astrophysics Center MadisonWI53703 United States Technology Service Corporation ArlingtonVA22202 United States

The ComPair balloon instrument is a prototype gamma-ray telescope that aims to further develop technology for observing the gamma-ray sky in the MeV regime. ComPair combines four detector subsystems to enable parallel Compton scattering and pair-production detection, critical for observing in this energy range. This includes a 10 layer double-sided silicon strip detector tracker, a virtual Frisch grid low energy CZT calorimeter, a high energy CsI calorimeter, and a plastic scintillator anti-coincidence detector. The inaugural balloon flight successfully launched from the Columbia Scientific Balloon Facility site in Fort Sumner, New Mexico, in late August 2023, lasting approximately 6.5 hours in duration. In this proceeding, we discuss the development of the ComPair balloon payload, the performance during flight, and early results. © 2024, CC BY-NC-ND.

关键词： Calorimeters

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Dual-Targeting EGCG/NO-Supplying protein assembled nanoparticles with Multi-Synergistic effects against atherosclerosis

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Chemical Engineering Journal 2024年 493卷

作者： Lin, Chi Cheng, Tsai-Mu Liu, Yun-Chun Hsu, Fang-Yu Shih, Chun-Ming Tsai, Min-Lang Shih, Chun-Che Mi, Fwu-Long Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei11031 Taiwan The PhD Program for Translational Medicine College of Medical Science and Technology Taipei Medical University Taipei11031 Taiwan Taipei Heart Institute Taipei Medical University Taipei11031 Taiwan Department of Food Science National Taiwan Ocean University Keelung20224 Taiwan Department of Biochemistry and Molecular Cell Biology School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Division of Cardiology and Cardiovascular Research Center Taipei Medical University Hospital Taipei11031 Taiwan Division of Cardiovascular Surgery Department of Surgery Wan Fang Hospital Taipei Medical University Taipei11031 Taiwan Institute of Clinical Medicine School of Medicine National Yang-Ming Chiao Tung University Taipei Taiwan Department of Surgery School of Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Graduate Institute of Nanomedicine and Medical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan International Ph.D. Program for Cell Therapy and Regeneration Medicine College of Medicine Taipei Medical University Taipei Taiwan

Limited therapeutic options are available to effectively preventing atherosclerosis. Inflammatory endothelial cells, foamy macrophages, and high protease levels contribute to atherosclerotic plaque formation. Studies have shown that catechins effectively scavenge reactive oxygen species (ROS), inhibit monocyte adhesion and reduce cholesterol levels, while nitric oxide (NO) enhances endothelial function. However, due to the poor stability and bioavailability of catechins and the toxicity from the burst release of current synthetic small molecules NO donor, effective delivery of these bioactive compounds to treat atherosclerosis is still a challenge. Herein, a catechin/protein-based NO donor co-delivery nanosystem was designed for combinatorial anti-atherosclerotic therapy. We engineered a (−)-epigallocatechin-3-gallate (EGCG)/NO-releasing protein co-assembled nanocomplex based on specific catechin-protein interactions. Furthermore, the nanocomplex was surface modified with fucoidan (Fu), a sulfated polysaccharide with anti-inflammatory activity. This nanocomplex exhibits sensitivity to ROS, pH, and enzymes. The Fu-functionalized nanoparticles specifically accumulates in atherosclerotic plaques mediated by P-selectin on inflamed endothelial cells and scavenger receptor A (SR-A) on foamy macrophages. Under environmental stimuli that simulate the condition of plaque, the nanoparticles are readily activated to release EGCG and NO in response to excess ROS and high protease levels, exerting the multi-synergistic anti-atherosclerosic effects on reducing monocyte adhesion, promoting NO production to proliferate endothelial cells, lowering ROS levels, and decreasing the foam cell formation in vitro, and reducing lipid accumulation, plaque size, and inflammatory cytokines release in high-fat diet-induced atherosclerosis model in ApoE−/− mice. The integration of plaques targeting ability and multiple therapeutic functions can provide an advanced therapeutic strategy for athero

关键词： Nitric oxide

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In-situ growth of novel iron oxide/iron organic framework composites as efficient electroactive materials of battery supercapacitor hybrids

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Journal of Energy Storage 2024年 97卷

作者： Kuo, Tsung-Rong Saukani, Muhammad Kuo, Tsung-Rong Kubendhiran, Subbiramaniyan Wang, Yu-Min Tai, Po-Chun Wu, Chang-Feng Lin, Lu-Yin Kongvarhodom, Chutima Kongvarhodom, Chutima Husain, Sadang Yougbaré, Sibidou Chen, Hung-Ming International PhD Program in Biomedical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Graduate Institute of Nanomedicine and Medical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Department of Chemical Engineering and Biotechnology National Taipei University of Technology Taipei Taiwan Department of Chemical Engineering King Mongkut's University of Technology Thonburi 126 Pracha-u-thit Toong-kru Bangkok10140 Thailand Department of Chemical Engineering University of New Brunswick FrederictonNBE3B5A3 Canada Department of Physics Faculty of Mathematics and Natural Science Lambung Mangkurat University Banjarmasin70124 Indonesia /Nanoro 03 B.P 7192 Ouagadougou03 Burkina Faso Gingen technology Co. LTD. Rm. 7 10F. No.189 Sec. 2 Keelung Rd. Xinyi Dist. Taipei11054 Taiwan

Iron oxide (Fe2O3) with a high theoretical capacitance, wide potential ranges and easy availability has attracted much attentions as the electrode material of battery supercapacitor hybrids (BSH). Metal–organic framework (MOF) is one of the promising potential energy storage materials due to its large surface area and controllable pore structures. In this work, novel iron oxide/iron organic framework composites (Fe2O3/FeMOF) are in-situ grown on the Ni foam as efficient energy storage electrodes of BSH. By tuning the solvothermal durations, the morphology changes from random sizes of sheets, regular grown vertical sheets, to flower-like structures. The d-spacing also increases for the Fe2O3/FeMOF synthesized using longer solvothermal durations. The optimal Fe2O3/FeMOF electrode synthesized using 9 h shows a high areal capacitance of 10.97 F/cm2 along with an areal capacity of 5.49 F/cm2 at the current density of 35 mA/cm2, owing to the most regular growth of sheets, the large d-spacing, and the smallest charge-transfer resistances. A BSH composed of the Fe2O3/FeMOF positive electrode and a graphene negative electrode shows a maximum energy density of 0.76 mWh/cm2 at 22.5 mW/cm2. The excellent long-term cycling stability with the capacitance retention of 85% and Coulombic efficiency of 98% are also achieved after 10,000 charge/discharge cycles. © 2024 Elsevier Ltd

关键词： Supercapacitor

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An ALMA Glimpse of Dense Molecular Filaments Associated with High-mass Protostellar Systems in the Large Magellanic Cloud

arXiv

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arXiv 2023年

作者： Tokuda, Kazuki Harada, Naoto Tanaka, Kei E.I. Inoue, Tsuyoshi Shimonishi, Takashi Zhang, Yichen Sewilo, Marta Kunitoshi, Yuri Konishi, Ayu Fukui, Yasuo Kawamura, Akiko Onishi, Toshikazu Machida, Masahiro N. Department of Earth and Planetary Sciences Faculty of Science Kyushu University Fukuoka Nishi-ku819-0395 Japan National Astronomical Observatory of Japan National Institutes of Natural Sciences 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Department of Earth and Planetary Sciences Tokyo Institute of Technology Meguro Tokyo152-8551 Japan Department of Physics Konan University Okamoto 8-9-1 Kobe Japan Environmental Science Program Faculty of Science Niigata University Ikarashi-ninocho 8050 Nishi-ku Niigata950-2181 Japan Department of Astronomy University of Virginia CharlottesvilleVA22904-4325 United States RIKEN Cluster for Pioneering Research Saitama Wako351-0198 Japan Exoplanets and Stellar Astrophysics Laboratory NASA Goddard Space Flight Center GreenbeltMD20771 United States Department of Astronomy University of Maryland College ParkMD20742 United States Center for Research and Exploration in Space Science and Technology NASA Goddard Space Flight Center GreenbeltMD20771 United States Department of Physics Graduate School of Science Osaka Metropolitan University 1-1 Gakuen-cho Naka-ku Sakai Osaka599-8531 Japan Department of Physics Nagoya University Furo-cho Chikusa-ku Nagoya464-8601 Japan

Recent millimeter/sub-millimeter facilities have revealed the physical properties of filamentary molecular clouds in relation to high-mass star formation. A uniform survey of the nearest, face-on star-forming galaxy, the Large Magellanic Cloud (LMC), complements the Galactic knowledge. We present ALMA survey data with a spatial resolution of ∼0.1 pc in the 0.87 mm continuum and HCO+(4–3) emission toward 30 protostellar objects with luminosities of 104–105.5 L☉ in the LMC. The spatial distributions of the HCO+(4–3) line and thermal dust emission are well correlated, indicating that the line effectively traces dense, filamentary gas with an H2 volume density of 105 cm−3 and a line mass of ∼103–104 M☉ pc−1. Furthermore, we obtain an increase in the velocity linewidths of filamentary clouds, which follows a power-law dependence on their H2 column densities with an exponent of ∼0.5. This trend is consistent with observations toward filamentary clouds in nearby star-forming regions withiin 1 kpc from us and suggests enhanced internal turbulence within the filaments owing to surrounding gas accretion. Among the 30 sources, we find that 14 are associated with hub-filamentary structures, and these complex structures predominantly appear in protostellar luminosities exceeding ∼5 ×104 L☉. The hub-filament systems tend to appear in the latest stages of their natal cloud evolution, often linked to prominent H ii regions and numerous stellar clusters. Our preliminary statistics suggest that the massive filaments accompanied by hub-type complex features may be a necessary intermediate product in forming extremely luminous high-mass stellar systems capable of ultimately dispersing the parent cloud. © 2023, CC BY.

关键词： Clouds

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Measuring 60-pc-scale Star Formation Rate of the Nearby Seyfert Galaxy NGC 1068 with ALMA, HST, VLT/MUSE, and VLA

arXiv

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arXiv 2024年

作者： Nagashima, Yuzuki Saito, Toshiki Ikarashi, Soh Takano, Shuro Nakanishi, Kouichiro Harada, Nanase Nakajima, Taku Taniguchi, Akio Tosaki, Tomoka Bamba, Kazuharu Physics and Mechatronics Course Major in Symbiotic Systems Science and Technology Graduate School of Symbiotic Systems Science and Technology Fukushima University 1 Kanayagawa Fukushima Fukushima960-1296 Japan National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Faculty of Global Interdisciplinary Science and Innovation Shizuoka University 836 Ohya Suruga-ku Shizuoka422-8529 Japan Department of Physics General Studies College of Engineering Nihon University Tamura-machi Fukushima Koriyama963-8642 Japan Astronomical Science Program Graduate Institute for Advanced Studies SOKENDAI 2-21-1 Osawa Mitaka Tokyo181-1855 Japan Institute for Space-Earth Environmental Research Nagoya University Furo-cho Chikusa-ku Aichi Nagoya464-8601 Japan Department of Physics Graduate School of Science Nagoya University Furo-cho Chikusa-ku Aichi Nagoya464-8602 Japan Department of Geoscience Joetsu University of Education Yamayashiki-machi Niigata Joetsu943-8512 Japan

Star formation rate (SFR) is a fundamental parameter for describing galaxies and inferring their evolutionary course. H II regions yield the best measure of instantaneous SFR in galaxies, although the derived SFR can have large uncertainties depending on tracers and assumptions. We present an SFR calibration for the entire molecular gas disk of the nearby Seyfert galaxy NGC 1068, based on our new high-sensitivity ALMA 100 GHz continuum data at 55 pc (= 0′′ . 8) resolution in combination with the HST Paα line data. In this calibration, we account for the spatial variations of dust extinction, electron temperature of H II regions, AGN contamination, and diffuse ionized gas (DIG) based on publicly available multi-wavelength data. Especially, given the extended nature and the possible non-negligible contribution to the total SFR, a careful consideration of DIG is essential. With a cross-calibration between two corrected ionized gas tracers (free-free continuum and Paα), the total SFR of the NGC 1068 disk is estimated to be 3.2 ± 0.5 M☉ yr−1, one-third of the SFR without accounting for DIG (9.1 ± 1.4 M☉ yr−1). We confirmed high SFR around the southern bar-end and the corotation radius, which is consistent with the previous SFR measurements. In addition, our total SFR exceeds the total SFR based on 8 µm dust emission by a factor of 1.5. We attribute this discrepancy to the differences in the young stars at different stages of evolution traced by each tracer and their respective timescales. This study provides an example to address the various uncertainties in conventional SFR measurements and their potential to lead to significant SFR miscalculations. © 2024, CC0.

关键词： Galaxies

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Effects of galaxy environment on merger fraction

arXiv

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arXiv 2024年

作者： Pearson, W.J. Santos, D.J.D. Goto, T. Huang, T.-C. Kim, S.J. Matsuhara, H. Pollo, A. Ho, S.C.-C. Hwang, H.S. Malek, K. Nakagawa, T. Romano, M. Serjeant, S. Suelves, L. Shim, H. White, G.J. National Centre for Nuclear Research Pasteura 7 Warszawa02-093 Poland Max Planck Institute for Extraterrestrial Physics Giesenbachstrase 1 GarchingD-85748 Germany Institute of Astronomy National Tsing Hua University 101 Section 2. Kuang-Fu Road Hsinchu30013 Taiwan Department of Space and Astronautical Science Graduate University for Advanced Studies SOKENDAI Shonankokusaimura Hayama Miura District Kanagawa240-0193 Japan Institute of Space and Astronautical Science Japan Aerospace Exploration Agency 3-1-1 Yoshinodai Chuo-ku Sagamihara Kanagawa252-5210 Japan Research School of Astronomy and Astrophysics The Australian National University CanberraACT2611 Australia Centre for Astrophysics and Supercomputing Swinburne University of Technology P.O. Box 218 HawthornVIC3122 Australia OzGrav: The Australian Research Council Centre of Excellence for GravitationalWave Discovery HawthornVIC3122 Australia ASTRO3D: The Australian Research Council Centre of Excellence for All-sky Astrophysics in 3D ACT2611 Australia Astronomy Program Department of Physics and Astronomy Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Center Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of INAF-Osservatorio Astronomico di Padova Vicolo dell'Osservatorio 5 PadovaI-35122 Italy School of Physical Sciences The Open University Walton Hall Milton KeynesMK7 6AA United Kingdom Department of Earth Science Education Kyungpook National University 80 Daehak-ro Buk-gu Daegu41566 Korea Republic of Space Science and Technology Division RALSpace STFC Rutherford Appleton Laboratory Chilton DidcotOX11 0QX United Kingdom

Aims. In this work, we intend to examine how environment influences the merger fraction, from the low density field environment to higher density groups and clusters. We also aim to study how the properties of a group or cluster, as well as the position of a galaxy in the group or cluster, influences the merger fraction. *** identified galaxy groups and clusters in the North Ecliptic Pole using a friends-of-friends algorithm and the local density. Once identified, we determined the central galaxies, group radii, velocity dispersions, and group masses of these groups and clusters. Merging systems were identified with a neural network as well as *** these, we examined how the merger fraction changes as the local density changes for all galaxies as well as how the merger fraction changes as the properties of the groups or clusters change. Results. We find that the merger fraction increases as local density increases and decreases as the velocity dispersion increases, as is often found in literature. A decrease in merger fraction as the group mass increases is also found. We also find groups with larger radii have higher merger fractions. The number of galaxies in a group does not influence the merger fraction. Conclusions. The decrease in merger fraction as group mass increases is a result of the link between group mass and velocity dispersion. Hence, this decrease of merger fraction with increasing mass is a result of the decrease of merger fraction with velocity dispersion. The increasing relation between group radii and merger fraction may be a result of larger groups having smaller velocity dispersion at a larger distance from the centre or larger groups hosting smaller, infalling groups with more mergers. However, we do not find evidence of smaller groups having higher merger fractions. Copyright © 2024, The Authors. All rights reserved.

关键词： Galaxies

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First-Principle-Integrated Study of Blazar Synchrotron Radiation and Polarization Signatures from Magnetic Turbulence

arXiv

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arXiv 2023年

作者： Zhang, Haocheng Marscher, Alan P. Guo, Fan Giannios, Dimitrios Li, Xiaocan Negro, Michela NASA Postdoctoral Program United States NASA Goddard Space Flight Center GreenbeltMD20771 United States Institute for Astrophysical Research Boston University BostonMA02215 United States Theoretical Division Los Alamos National Lab Los AlamosNM87545 United States Department of Physics and Astronomy Purdue University West LafayetteIN47907 United States Dartmouth College HanoverNH03750 United States University of Maryland Baltimore County BaltimoreMD21250 United States Center for Research and Exploration in Space Science and Technology NASA/GSFC GreenbeltMD20771 United States

Blazar emission is dominated by nonthermal radiation processes that are highly variable across the entire electromagnetic spectrum. Turbulence, which can be a major source of nonthermal particle acceleration, can widely exist in the blazar emission region. The Turbulent Extreme Multi-Zone (TEMZ) model has been used to describe turbulent radiation signatures. Recent particle-in-cell (PIC) simulations have also revealed the stochastic nature of the turbulent emission region and particle acceleration therein. However, radiation signatures have not been systematically studied via first-principle-integrated simulations. In this paper, we perform combined PIC and polarized radiative transfer simulations to study synchrotron emission from magnetic turbulence in the blazar emission region. We find that the multi-wavelength flux and polarization are generally characterized by stochastic patterns. Specifically, the variability time scale and average polarization degree (PD) are governed by the correlation length of the turbulence. Interestingly, magnetic turbulence can result in polarization angle (PA) swings with arbitrary amplitudes and duration, in either direction, that are not associated with changes in flux or PD. Surprisingly, these swings, which are stochastic in nature, can appear either bumpy or smooth, although large amplitude swings (> 180◦) are very rare, as expected. Our radiation and polarization signatures from first-principle-integrated simulations are consistent with the TEMZ model, except that in the latter there is a weak correlation, with zero lag, between flux and degree of polarization. Copyright © 2023, The Authors. All rights reserved.

关键词： Polarization

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Overexpression of tyrosine phosphorylated proteins in reproductive tissues of polycystic ovary syndrome rats induced by letrozole

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Asian pacific Journal of Reproduction 2020年第6期9卷 275-282页

作者： Sudtida Bunsueb Supatcharee Arun Arada Chaiyamoon Alexander Tsang-Hsien Wu Sitthichai Iamsaard Department of Anatomy Faculty of MedicineKhon Kaen UniversityKhon Kaen40002Thailand Research Institute for Human High Performance and Health Promotion Khon Kaen University40002Khon KaenThailand The PhD Program for Translational Medicine College of Medical Science and TechnologyTaipei Medical University and Academia SinicaTaipei Graduate Institute of Medical Sciences National Defense Medical CenterTaipei

Objective:To identify the alteration of tyrosine phosphorylated protein expression in rats with polycystic ovary syndrome(PCOS).Methods:Sixteen female Sprague-Dawley rats were divided into the control and letrozole-induced PCOS *** oestrus cycle of rats was performed by vaginal *** hormones and morphology of the ovary,oviduct,and uterus were *** and intensity of androgen receptor and tyrosine phosphorylated proteins of reproductive organs were investigated by Western ***:Various polycysts and increased androgen receptor expression were present in the ovary of the PCOS *** levels of follicle-stimulating hormone and testosteone were significantly higher in the PCOS group while progesterone and estradiol levels were significantly decreased as compared with the control group(P<0.05).Only the size of uterus in the PCOS group was significantly smaller than the control ***,the density of collagen fibers observed in PCOS uterus was greater than the control ***,tyrosine phosphorylated proteins were significantly overexpressed in ovary(52,42,and 28 kDa),oviduct(72,56,42,and 28 kDa),and uterus(53 and 42 kDa)of the PCOS group compared to the control ***:Presence of tyrosine phosphorylated proteins in the ovary,oviduct and uterus suggests that overexpression of tyrosine phosphorylated proteins may be involved in potential mechanism of female infertility especially in PCOS.

关键词： Polycystic ovary syndrome Overexpression Tyrosine phosphorylated proteins Ovary Oviduct Uterus

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AGE OF MASSIVE GALAXIES AT REDSHIFT 8

arXiv

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arXiv 2024年

作者： López-Corredoira, Martin V. Melia, F. Wei, J.-J. Gao, C.-Y. Instituto de Astrofisica de Canarias La Laguna TenerifeE-38205 Spain PIFI-Visiting Scientist 2023 Chinese Academy of Sciences at PMO6 National Astronomical Observatories Beijing100012 China Departamento de Astrofisica Universidad de La Laguna La Laguna TenerifeE-38206 Spain Department of Physics The Applied Math Program Department of Astronomy The University of Arizona AZ 85721 United States Purple Mountain Observatory Chinese Academy of Sciences Nanjing210023 China School of Astronomy and Space Sciences University of Science and Technology of China Hefei230026 China

Recent James Webb space Telescope (JWST) data analyses have shown that massive red galaxies existed at redshifts z >∼ 6, a discovery that is difficult to understand in the context of standard cosmology (ΛCDM). Here we analyze these observations more deeply by fitting a stellar population model to the optical and near-infrared photometric data. These fits include a main stellar population in addition to a residual younger population and with the same extinction for both (a lower extinction for the younger population is unphysical). Extra stellar populations or the inclusion of an AGN component do not significantly improve the fits. These galaxies are being viewed at very high redshifts, with an average ≈ 8.2, when the ΛCDM Universe was only ≈ 600 Myr old. This result conflicts with the inferred ages of these galaxies, however, which were on average between 0.9 and 2.4 Gyr old within 95% CL. Given the sequence of star formation and galaxy assembly in the standard model, these galaxies should instead be even younger than 290 Myr on average, for which our analysis assigns a probability of only −4 ( 3.6σ tension). This outcome may indicate the need to consider non-standard cosmologies. Nevertheless, our conclusions result from several approximations in stellar astrophysics and extinction, so they should be taken with a grain of salt. Further research is necessary to corroborate the possible existence of galaxies older than the ΛCDM universe at their observed redshifts. Copyright © 2024, The Authors. All rights reserved.

关键词： Galaxies

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ComPair-2: A Next Generation Medium Energy Gamma-ray Telescope Prototype

arXiv

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arXiv 2024年

作者： Caputo, Regina Kierans, Carolyn Cannady, Nicholas Falcone, Abe Fukazawa, Yasushi Jadhav, Manoj Kerr, Matthew Kirschner, Nicholas Kumar, Kavic Laviron, Adrien Leys, Richard McEnery, Julie Metcalfe, Jessica Metzler, Zachary Miller, Nathan Mitchell, John Parker, Lucas Peric, Ivan Perkins, Jeremy Phlips, Bernard Racusin, Judith Sasaki, Makoto Segal, Kenneth N. Shy, Daniel Steinhebel, Amanda L. Striebig, Nicolas Suda, Yusuke Tajima, Hiroyasu Valverde, Janeth Violette, Daniel P. Woolf, Richard Zoglauer, Andreas NASA Goddard Space Flight Center MD United States University of Maryland Baltimore CountyMD United States Center for Research and Exploration in Space Science and Technology Maryland United States The Pennsylvania State University PA United States Hiroshima University Hiroshima Japan Argonne National Laboratory Illinois United States Naval Research Laboratory WashingtonDC United States The George Washington University WashingtonDC United States University of Maryland College ParkMD United States Laboratoire Leprince-Ringuet CNRS IN2P3 École Polytechnique Institut Polytechnique de Paris Palaiseau France Karlsruher Institut für Technologie Germany John Hopkins University MD United States Los Alamos National Laboratory New Mexico United States Heliospace Corporation BerkeleyCA United States NASA Postdoctoral Program Fellow United States Nagoya University Nagoya Japan Space Sciences Laboratory University of California BerkeleyCA United States

Many questions posed in the Astro2020 Decadal survey in both the New Messengers and New Physics and the Cosmic Ecosystems science themes require a gamma-ray mission with capabilities exceeding those of existing (e.g. Fermi, Swift) and planned (e.g. COSI) observatories. ComPair, the Compton Pair telescope, is a prototype of such a next-generation gamma-ray mission. It had its inaugural balloon flight from Ft. Sumner, New Mexico in August 2023. To continue the goals of the ComPair project to develop technologies that will enable a future gamma-ray mission, the next generation of ComPair (ComPair-2) will be upgraded to increase the sensitivity and low-energy transient capabilities of the instrument. These advancements are enabled by AstroPix, a silicon monolithic active pixel sensor, in the tracker and custom dual-gain silicon photomultipliers and front-end electronics in the calorimeter. This effort builds on design work for the All-sky Medium Energy Gamma-ray Observatory eXplorer (AMEGO-X) concept that was submitted the 2021 MIDEX Announcement of Opportunity. Here we describe the ComPair-2 prototype design and integration and testing plans to advance the readiness level of these novel technologies. Copyright © 2024, The Authors. All rights reserved.

关键词： Cosmology

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