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arXiv 2024年

作者： Coelho, Rodrigo C.V. Zhao, Hanqing Amaral, Guilherme N.C. Smalyukh, Ivan I. Telo da Gama, Margarida M. Tasinkevych, Mykola Centro de Física Teórica e Computacional Faculdade de Ciências Universidade de Lisboa Lisboa1749-016 Portugal Departamento de Física Faculdade de Ciências Universidade de Lisboa LisboaP-1749-016 Portugal Department of Physics and Soft Materials Research Center University of Colorado BoulderCO80309 United States Department of Electrical Computer and Energy Engineering Materials Science and Engineering Program University of Colorado BoulderCO80309 United States Renewable and Sustainable Energy Institute National Renewable Energy Laboratory University of Colorado BoulderCO80309 United States International Institute for Sustainability Knotted Chiral Meta Matter Hiroshima University Higashihiroshima739-8511 Japan SOFT Group School of Science and Technology Nottingham Trent University Clifton Lane NottinghamNG11 8NS United Kingdom

Topology establishes a unifying framework for a diverse range of scientific areas including particle physics, cosmology, and condensed matter physics. One of the most fascinating manifestations of topology in the context of condensed matter is the topological Hall effect, and its relative: the Skyrmion Hall effect. Skyrmions are stable vortex-like spin configurations in certain chiral magnets, and when subject to external electric currents can drift in the transverse direction to the current. These quasi-particles are characterised by a conserved topological charge which in the Skyrmion Hall effect plays the role of electric charges in the ordinary Hall effect. Recently, it has been shown that liquid crystals endowed with chiral properties serve as an ideal testbed for the fundamental investigation of topological solitons, including their two- and three-dimensional realisations. Here, we show experimentally and numerically that three-dimensional solitons aka"torons" exhibit a Hall-like effect when driven by shear flows: the torons are deflected in the direction perpendicular to the shear plane. The experimental results are rationalised in terms of the dynamic ericksen-Leslie equations, which predict the emergence of the transverse component of the net mass flow, the magnitude of which scales as the 3rd power of the shear rate. The perturbation analysis highlights an interplay of the viscous and chiral elastic torques as the mechanism for the emergence of net transverse currents. Numerical simulations demonstrate, however, that torons are not merely dragged by the flow but move with their own transverse speed, much larger than the average flow velocity in the transverse direction. Our findings may enable responsive microfluidic applications relying on soft topological solitons. Copyright © 2024, The Authors. All rights reserved.

关键词： Liquid crystals

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Liquid crystal torons in Poiseuille-like flows

arXiv

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arXiv 2024年

作者： Amaral, Guilherme N.C. Zhao, Hanqing Sedahmed, Mahmoud Campante, Tomás Smalyukh, Ivan I. Tasinkevych, Mykola Telo da Gama, Margarida M. Coelho, Rodrigo C.V. Centro de Física Teórica e Computacional Faculdade de Ciências Universidade de Lisboa Lisboa1749-016 Portugal Departamento de Física Faculdade de Ciências Universidade de Lisboa LisboaP-1749-016 Portugal Department of Physics Soft Materials Research Center University of Colorado BoulderCO80309 United States Department of Electrical Computer and Energy Engineering Materials Science and Engineering Program University of Colorado BoulderCO80309 United States Renewable and Sustainable Energy Institute National Renewable Energy Laboratory University of Colorado BoulderCO80309 United States International Institute for Sustainability with Knotted Chiral Meta Matter Hiroshima University Higashihiroshima739-8511 Japan SOFT Group School of Science and Technology Nottingham Trent University Clifton Lane NottinghamNG11 8NS United Kingdom

Three-dimensional (3D) simulations of the structure of liquid crystal (LC) torons, topologically protected distortions of the LC director field, under material flows are rare but essential in microfluidic applications. Here, we show that torons adopt a steady-state configuration at low flow velocity before disintegrating at higher velocities, in line with experimental results. Furthermore, we show that under partial slip conditions at the boundaries, the flow induces a reversible elongation of the torons, also consistent with the experimental observations. These results are in contrast with previous simulation results for 2D skyrmions under similar flow conditions, highlighting the need for a 3D description of this LC soliton in relation to its coupling to the material flow. These findings pave the way for future studies of other topological solitons, like hopfions and heliknotons, in flowing soft matter systems. Copyright © 2024, The Authors. All rights reserved.

关键词： Crystal structure

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The SCUBA-2 Large eXtragalactic Survey: 850 μm map, catalogue and the bright-end number counts of the XMM-LSS field

arXiv

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arXiv 2023年

作者： Garratt, T.K. Geach, J.e. Tamura, Y. Coppin, K.e.K. Franco, M. Ao, Y. Chen, C.-C. Cheng, C. Clements, D.L. Dai, Y.S. Dannerbauer, H. Greve, T.R. Hatsukade, B. Hwang, H.S. Jiang, L. Kohno, K. Koprowski, M.P. Michalowski, M.J. Sawicki, M. Scott, D. Shim, H. Takeuchi, T.T. Wang, W.-H. Xue, Y.Q. Yang, C. Centre for Astrophysics Research University of Hertfordshire HatfieldAL10 9AB United Kingdom Division of Particle and Astrophysical Science Nagoya University Aichi Nagoya464-8602 Japan Purple Mountain Observatory Key Laboratory for Radio Astronomy Chinese Academy of Sciences 10 Yuanhua Road Nanjing210023 China School of Astronomy and Space Science University of Science and Technology of China Anhui Hefei230026 China Academia Sinica Institute of Astronomy and Astrophysics No. 1 Section 4 Roosevelt Road Taipei10617 Taiwan Chinese Academy of Sciences South America Center for Astronomy National Astronomical Observatories CAS Beijing100101 China Imperial College London Blackett Lab Prince Consort Road LondonSW7 2AZ United Kingdom National Astronomical Observatories Chinese Academy of Sciences 20A Datun RoadChaoyang District Beijing100101 China Tenerife La LagunaE-38205 Spain Universidad de La Laguna Dpto. Astrofísica Tenerife La LagunaE-38206 Spain National Space Institute DTU Space Technical University of Denmark Elektrovej 327 Kgs. LyngbyDK-2800 Denmark Department of Physics and Astronomy University College London Gower Street LondonWC1E 6BT United Kingdom Institute of Astronomy Graduate School of Science The University of Tokyo 2-21-1 Osawa Tokyo Mitaka181-0015 Japan Astronomy Program Department of Physics and Astronomy Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Center Astronomy Program Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of Kavli Institute for Astronomy and Astrophysics Peking University No. 5 Yiheyuan Road Haidian District Beijing100871 China Institute of Astronomy Faculty of Physics Astronomy and Informatics Nicolaus Copernicus University Grudziadzka 5 Torun87-100 Poland Astronomical Observatory Institute Faculty of Physics Adam Mickiewicz University ul. Sloneczna 36 Poznań60-286 Poland Department of Astronomy and P

We present 850 μm imaging of the XMM-LSS field observed for 170 hours as part of the James Clerk Maxwell Telescope SCUBA-2 Large eXtragalactic Survey (S2LXS). S2LXS XMM-LSS maps an area of 9 deg2, reaching a moderate depth of 1σ 4 mJy beam−1. This is the largest contiguous area of extragalactic sky mapped by JCMT at 850 μm to date. The wide area of the S2LXS XMM-LSS survey allows us to probe the ultra-bright (S850μm & 15 mJy), yet rare submillimetre population. We present the S2LXS XMM-LSS catalogue, which comprises 40 sources detected at >5σ significance, with deboosted flux densities in the range of 7 mJy to 48 mJy. We robustly measure the bright-end of the 850 μm number counts at flux densities >7 mJy, reducing the Poisson errors compared to existing measurements. The S2LXS XMM-LSS observed number counts show the characteristic upturn at bright fluxes, expected to be motivated by local sources of submillimetre emission and high-redshift strongly lensed galaxies. We find that the observed 850 μm number counts are best reproduced by model predictions that include either strong lensing or source blending from a 15 arcsec beam, indicating that both may make an important contribution to the observed over-abundance of bright single dish 850 μm selected sources. We make the S2LXS XMM-LSS 850 μm map and >5σ catalogue presented here publicly available. Copyright © 2023, The Authors. All rights reserved.

关键词： Blending

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Sculpting liquid crystal skyrmions with external flows

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Physical Review Research 2023年第3期5卷 033210-033210页

作者： Rodrigo C. V. Coelho Hanqing Zhao Mykola Tasinkevych Ivan I. Smalyukh Margarida M. Telo da Gama Centro de Física Teórica e Computacional Faculdade de Ciências Universidade de Lisboa 1749-016 Lisboa Portugal Departamento de Física Faculdade de Ciências Universidade de Lisboa P-1749-016 Lisboa Portugal Department of Physics and Soft Materials Research Center University of Colorado Boulder Colorado 80309 USA SOFT Group School of Science and Technology Nottingham Trent University Clifton Lane Nottingham NG11 8NS United Kingdom International Institute for Sustainability with Knotted Chiral Meta Matter Hiroshima University Higashihiroshima 739-8511 Japan Department of Electrical Computer and Energy Engineering and Materials Science and Engineering Program University of Colorado Boulder Colorado 80309 USA Renewable and Sustainable Energy Institute National Renewable Energy Laboratory and University of Colorado Boulder Colorado 80309 USA

We investigate, using experiments and numerical simulations, the distortions and the alignment of skyrmions in liquid crystal under external flows for a range of average flow velocities. The simulations are based on the Landau-de Gennes Q tensor theory both for isolated as well as for systems with many skyrmions. We found striking flow-driven elongation of an isolated skyrmion and flow alignment of skyrmions in the many-skyrmion system, both of which are also observed in the experiments. In the simulations, particular attention was given to the dissipation rate and to the various dissipation channels for a single skyrmion under external flow. This analysis provides insight on the observed scaling regime of the elongation of isolated flowing skyrmions and revealed a surprising plastic response at very short times, which may be relevant in applications based on the alignment of soft structures such as liquid crystal skyrmions.

关键词： Complex fluids Living matter & active matter Lattice-Boltzmann methods Optical microscopy Photoluminescence

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The escalating threat of human-associated infectious bacteria in surface aquatic resources: Insights into prevalence, antibiotic resistance, survival mechanisms, detection, and prevention strategies

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Journal of Contaminant Hydrology 2024年 265卷 104371页

作者： Asif, Aslia Chen, Jung-Sheng Hussain, Bashir Hsu, Gwo-Jong Rathod, Jagat Huang, Shih-Wei Wu, Chin-Chia Hsu, Bing-Mu Department of Earth and Environmental Sciences National Chung Cheng University Chiayi County Taiwan Doctoral Program in Science Technology Environment and Mathematics National Chung Cheng University Chiayi County Taiwan Department of Medical Research E-Da Hospital I-Shou University Kaohsiung Taiwan Division of Infectious Disease and Department of Internal Medicine Chiayi Christian Hospital Chiayi Taiwan Department of Environmental Biotechnology Gujarat Biotechnology University Near Gujarat International Finance and Tec (GIFT)-City Gujarat Gandhinagar 382355 India Institute of Environmental Toxin and Emerging Contaminant Cheng Shiu University Kaohsiung Taiwan Center for Environmental Toxin and Emerging Contaminant Research Cheng Shiu University Kaohsiung Taiwan Division of Colorectal Surgery Dalin Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation Chiayi Taiwan

Anthropogenic activities and climate change profoundly impact water quality, leading to a concerning increase in the prevalence and abundance of bacterial pathogens across diverse aquatic environments. This rise has resulted in a growing challenge concerning the safety of water sources, particularly surface waters and marine environments. This comprehensive review delves into the multifaceted challenges presented by bacterial pathogens, emphasizing threads to human health within ground and surface waters, including marine ecosystems. The exploration encompasses the intricate survival mechanisms employed by bacterial pathogens and the proliferation of antimicrobial resistance, largely driven by human-generated antibiotic contamination in aquatic systems. The review further addresses prevalent pathogenic bacteria, elucidating associated risk factors, exploring their eco-physiology, and discussing the production of potent toxins. The spectrum of detection techniques, ranging from conventional to cutting-edge molecular approaches, is thoroughly examined to underscore their significance in identifying and understanding waterborne bacterial pathogens. A critical aspect highlighted in this review is the imperative for real-time monitoring of biomarkers associated with waterborne bacterial pathogens. This monitoring serves as an early warning system, facilitating the swift implementation of action plans to preserve and protect global water resources. In conclusion, this comprehensive review provides fresh insights and perspectives, emphasizing the paramount importance of preserving the quality of aquatic resources to safeguard human health on a global scale. © 2024

关键词： Anti-microbial resistance Infectious diseases Pathogen survival Pathogenic bacteria Surface aquatic resources

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Rapid dispatch for out-of-hospital cardiac arrest is associated with improved survival

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Resuscitation 2021年 163卷 176-183页

作者： Gnesin, Filip Møller, Amalie Lykkemark Mills, elisabeth Helen Anna Zylyftari, Nertila Jensen, Britta Bøggild, Henrik Ringgren, Kristian Bundgaard Blomberg, Stig Nikolaj Fasmer Christensen, Helle Collatz Kragholm, Kristian Lippert, Freddy Folke, Fredrik Torp-Pedersen, Christian Department of Research Nordsjællands Hospital Dyrehavevej 29 Hillerød 3400 Denmark Department of Cardiology Aalborg University Hospital Hobrovej 18-22 Aalborg 9000 Denmark Department of Cardiology Copenhagen University Hospital Herlev and Gentofte Gentofte Hospitalsvej 6 Hellerup 2900 Denmark Public Health and Epidemiology Department of Health Science and Technology Aalborg University Niels Jernes Vej 14 Aalborg E 9220 Denmark Copenhagen Emergency Medical Services University of Copenhagen Telegrafvej 5 Ballerup 2750 Denmark University of Copenhagen Blegdamsvej 9 København Ø 2100 Denmark Danish Clinical Quality Program (RKKP) National Clinical Registries Nordre Fasanvej 57 Frederiksberg 2000 Denmark

Aim: As proxy for initiation of the first link in the Chain of Survival by the dispatcher, we aimed to investigate the effect of time to first dispatch on 30-day survival among patients with OHCA ultimately receiving the highest-level emergency medical response. Methods: We linked data on all OHCA unwitnessed by emergency medical services (eMS) treated by Copenhagen eMS from 2016 through 2018 to corresponding emergency call records. Among patients receiving highest priority emergency response, we calculated time to dispatch as time from start of call to time of first dispatch. Results: We included 3548 patients with OHCA. Of these, 94.1% received the highest priority response (median time to dispatch 0.84 min, 25th–75th percentile 0.58–1.24 min). Patients with time to dispatch within one minute compared to three or more minutes were more likely to receive bystander cardiopulmonary resuscitation (77.3 vs 54.2%), bystander defibrillation (11.5 vs 6.5%) and defibrillation by emergency medical services (24.1 vs 7.5%) and were 2.6-fold more likely to survive 30 days after the OHCA (P = 0.004). Results from multivariate logistic regression were similar: odds ratio (OR) of survival 0.83 per minute increase (95% confidence interval 0.70–1.00, P = 0.04). However, survival was similar between those who received highest priority response and those who did not: OR of survival 0.88 (95% confidence interval 0.53–1.46, P = 0.61). Conclusion: Rapid time to dispatch among patients with highest priority response was significantly associated with a higher probability of 30-day survival following OHCA. © 2021 elsevier B.V.

关键词： Automated external defibrillators Cardiopulmonary resuscitation emergency medical dispatch emergency medical response emergency medical services Out-of-hospital cardiac arrest Public health Time to dispatch

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Assessment of the therapeutic potential of a novel phosphoramidate acyclic nucleoside on induced hepatocellular carcinoma in rat model

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Life sciences 2024年 122669页

作者： Youssef A Said Sherif F Hammad Mariam I Halim Ahmed Abd el-Moneim Ahmed Osman Biotechnology Program Basic and Applied Sciences Institute Egypt-Japan University of Science and Technology (E-JUST) 21934 New Borg El-Arab City Alexandria Egypt Biochemistry Department Faculty of Science Ain Shams University 11566 Cairo Egypt. Electronic address: youssef.farghali@ejust.edu.eg. Medicinal Chemistry Department PharmD Program Egypt-Japan University of Science and Technology (E-JUST) 21934 New Borg El-Arab City Alexandria Egypt Pharmaceutical Chemistry Department Faculty of Pharmacy Helwan University 11795 Cairo Egypt. Pathology Department Faculty of Medicine Ain Shams University 11566 Cairo Egypt. Graphene Center of Excellence Egypt-Japan University of Science and Technology (E-JUST) 21934 New Borg El-Arab City Alexandria Egypt Physical Chemistry Department National Research Centre (NRC) 12622 Cairo Egypt. Biochemistry Department Faculty of Science Ain Shams University 11566 Cairo Egypt.

AIMS:Hepatocellular Carcinoma (HCC) is renowned as a deadly primary cancer of hepatic origin. Sorafenib is the drug-of-choice for targeted treatment of unresectable end-stage HCC. Unfortunately, great proportion of HCC patients showed intolerance or unresponsiveness to treatment. This study assesses potency of novel ProTide; SH-PAN-19 against N-Nitrosodiethylamine (DeN)-induced HCC in male Wistar rats, compared to Sorafenib. MAIN MeTHODS:Structural entity of the synthesized compound was substantiated via FT-IR, UV-Vis, H NMR and C NMR spectroscopic analysis. In vitro, SH-PAN-19 cytotoxicity was tested against 3 human cell lines; hepatocellular carcinoma; HepG-2, colorectal carcinoma; HCT-116 and normal fibroblasts; MRC-5. In vivo, therapeutic efficacy of SH-PAN-19 (300 mg/kg b.w./day) against HCC could be revealed and compared to that of Sorafenib (15 mg/kg b.w./day) by evaluating the morphometric, biochemical, histopathological, immunohistochemical and molecular key markers. KeY FINDINGS:SH-PAN-19 was relatively safe toward MRC-5 cells (IC = 307.6 μg/mL), highly cytotoxic to HepG-2 cells (IC = 24.9 μg/mL) and prominently hepato-selective (TSI = 12.35). Oral LD of SH-PAN-19 was >3000 mg/kg b.w. DeN-injected rats suffered hepatomegaly, oxidative stress, elevated liver enzymes, hypoalbuminemia, bilirubinemia and skyrocketed AFP plasma titre. SH-PAN-19 alleviated the DeN-induced alterations in apoptotic, angiogenic and inflammatory markers. SH-PAN-19 produced a 2.5-folds increase in Caspase-9 and downregulated VeGFR-2, IL-6, TNF-α, TGFβ-1, MMP-9 and CcnD-1 to levels comparable to that elicited by Sorafenib. SH-PAN-19 resulted in near-complete pathological response versus partial response achieved by Sorafenib. SIGNIFICANCe:This research illustrated that SH-PAN-19 is a promising chemotherapeutic agent capable of restoring cellular plasticity and could stop HCC progression.

关键词： Diethylnitrosamine Hepatocellular carcinoma Phosphoramidate acyclic nucleoside Rat model Sorafenib

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Microencapsulation of Pediococcus pentosaceus using cupuassu flour-based as wall material: Application and impact on petit suisse cheese

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Food Bioscience 2025年 71卷

作者： Katherine Gutiérrez-Álzate Gabriele de Abreu Barreto Bruna Samara S. Rekowsky Letícia Alencar Pereira Rodrigues Deborah Murowaniecki Otero Marion Pereira da Costa Program in Food Science (PGAli) Faculty of Pharmacy Federal University of Bahia (UFBA) Salvador CEP 40170-115 BA Brazil Laboratorio de Inspeção e Tecnologia de Leite e Derivados (LAITLACTEOS) Federal University of Bahia (UFBA) Salvador CEP 40170-110 BA Brazil Faculty of Technology SENAI/CIMATEC National Service of Industrial Learning–SENAI Salvador Bahia Brazil SENAI Institute of Innovation (ISI) in Health Advanced Systems (CIMATEC ISI SAS) Senai Cimatec University Center Salvador 41650-010 Brazil Graduate Program in Animal Science in the Tropics (PPGCAT) School of Veterinary Medicine and Zootchniques Federal University of Bahia (UFBA) Ondina Salvador 40170-110 BA Brazil Biotechnology Laboratory Center of Excellence in Alternative Proteins SENAI CIMATEC University Center Salvador 41650-010 Brazil Graduate Program in Food Nutrition and Health Nutrition School Federal University of Bahia (UFBA) Campus Canela Salvador 40110-907 BA Brazil

Microencapsulation enhances probiotic viability under adverse conditions. This study introduces cupuassu ( Theobroma grandiflorum ) flour, a novel plant-based by-product, as a wall material for spray-dried Pediococcus pentosaceus microcapsules. In addition, the study also aims to explore the application and impact of this innovative material on Petit Suisse cheese, presenting unique findings that contribute to the advancement of dairy science. Five formulations were developed using sodium alginate (1 %) with varying levels of cupuassu flour (0, 1, 2 and 3 %) and inulin (1 %). The microcapsules were characterized for moisture, dispersibility, hygroscopicity, and particle size, as well as by FTIR spectroscopy, thermal behavior (TGA/DTG), and morphology by SeM. Selected microcapsules were incorporated into Petit Suisse cheese, and their effects on pH, viscosity, color, and probiotic viability were monitored during 28 days of refrigerated storage. Results showed encapsulation efficiencies between 73.2 % and 82.2 %, and viability above 6.4 log CFU/g after 75 days at −18 °C. Cupuassu flour improved the physicochemical stability and thermal resistance of the microcapsules. In the dairy matrix, microcapsules influenced texture and acidity while ensuring probiotic retention. This study highlights the potential of cupuassu flour as a functional and sustainable biopolymer, expanding the technological applications of probiotics in the dairy industry.

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Advising big data transfer over dedicated connections based on profiling optimization

Advising big data transfer over dedicated connections based ...

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作者： Yun, Daqing Wu, Chase Q. Rao, Nageswara S. V. Kettimuthu, Rajkumar Computer and Information Sciences Program Harrisburg University HarrisburgPA17101 United States Department of Computer Science New Jersey Institute of Technology NewarkNJ07102 United States Computer Science and Mathematics Division Oak Ridge National Laboratory Oak RidgeTN37831 United States Data Science and Learning Division Argonne National Laboratory ArgonneIL60439 United States

Big data transfer in next-generation scientific applications is now commonly carried out over dedicated channels in high-performance networks (HPNs), where transport protocols play a critical role in maximizing application-level throughput. Optimizing the performance of these protocols is challenging: i) transport protocols perform differently in various network environments, and the protocol choice is not straightforward;ii) even for a given protocol in a given environment, different parameter settings of the protocol may lead to significantly different performance and oftentimes the default setting does not yield the best performance. However, it is prohibitively time-consuming to conduct exhaustive transport profiling due to the large parameter space. In this paper, we propose a PRofiling Optimization Based DAta Transfer Advisor (ProbData) to help end users determine the most effective transport method with the most appropriate parameter settings to achieve satisfactory performance for big data transfer over dedicated connections in HPNs. ProbData employs a fast profiling scheme based on the Simultaneous Perturbation Stochastic Approximation algorithm, namely, FastProf, to accelerate the exploration of the optimal operational zones of various transport methods to improve profiling efficiency. We first present a theoretical background of the optimized profiling approach in ProbData and then detail its design and implementation. The advising procedure and performance benefits of FastProf and ProbData are illustrated and evaluated by both extensive emulations based on real-life performance measurements and experiments over various physical connections in existing production HPNs. © 1993-2012 Ieee.

关键词： Data transfer

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Revisiting the Transit Timing and Atmosphere Characterization of the Neptune-mass Planet HAT-P-26 b

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Astronomical Journal 2023年第6期166卷 223-223页

作者： A-Thano, Napaporn Awiphan, Supachai Jiang, Ing-Guey Kerins, eamonn Priyadarshi, Akshay McDonald, Iain Joshi, Yogesh C. Chulikorn, Thansuda Hayes, Joshua J. C. Charles, Stephen Huang, Chung-Kai Rattanamala, Ronnakrit Yeh, Li-Chin Dhillon, Vik S Department of Physics Institute of Astronomy National Tsing-Hua University Hsinchu 30013 Taiwan National Astronomical Research Institute of Thail 260 Moo 4 Donkaew Mae Rim Chiang Mai 50180 Thailand Jodrell Bank Centre for Astrophysics University of Manchester Oxford Road Manchester M13 9PL United Kingdom Department of Physical Sciences The Open University Walton Hall Milton Keynes MK7 6AA United Kingdom Aryabhatta Research Institute of Observational Sciences (ARIES) Manora Peak Nainital 263001 India Department of Physics Faculty of Science Chulalongkorn University 254 Phayathai Road Pathumwan Bangkok 10330 Thailand Institute of Astronomy and Astrophysics Academia Sinica No.1 Sec. 4 Roosevelt Road Taipei 10617 Taiwan PhD Program in Astronomy Department of Physics and Materials Science Faculty of Science Chiang Mai University Chiang Mai 50200 Thailand Department of Physics and General Science Faculty of Science and Technology Nakhon Ratchasima Rajabhat University Nakhon Ratchasima 30000 Thailand Institute of Computational and Modeling Science National Tsing-Hua University Hsinchu 30013 Taiwan Department of Physics and Astronomy University of Sheffield Sheffield S3 7RH United Kingdom Instituto de Astrofísica de Canarias La Laguna Tenerife E-38205 Spain

We present a transit-timing variation (TTV) and planetary atmosphere analysis of the Neptune-mass planet HAT-P-26 b. We present a new set of 13 transit light curves from optical ground-based observations and combine them with light curves from the Wide Field Camera 3 on the Hubble Space Telescope, the Transiting exoplanet Survey Satellite, and previously published ground-based data. We refine the planetary parameters of HAT-P-26 b and undertake a TTV analysis using 33 transits obtained over seven years. The TTV analysis shows an amplitude signal of 1.98 ± 0.05 minutes, which could result from the presence of an additional ∼0.02 M _Jup planet at a 1:2 mean-motion resonance orbit. Using a combination of transit depths spanning optical to near-infrared wavelengths, we find that the atmosphere of HAT-P-26 b contains 2.4 − 1.6 + 2.9 % H₂O with a derived temperature of 590 − 50 + 60 K. © 2023. The Author(s). Published by the American Astronomical Society.

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