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Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Nature communications 2021年第1期12卷 995页

作者： Vasiliki Lagou Reedik Mägi Jouke- Jan Hottenga Harald Grallert John R B Perry Nabila Bouatia-Naji Letizia Marullo Denis Rybin Rick Jansen Josine L Min Antigone S Dimas Anna Ulrich Liudmila Zudina Jesper R Gådin Longda Jiang Alessia Faggian Amélie Bonnefond Joao Fadista Maria G Stathopoulou Aaron Isaacs Sara M Willems Pau Navarro Toshiko Tanaka Anne U Jackson May e Montasser Jeff R O'Connell Lawrence F Bielak Rebecca J Webster Richa Saxena Jeanette M Stafford Beate St Pourcain Nicholas J Timpson Perttu Salo So-Youn Shin Najaf Amin Albert V Smith Guo Li Niek Verweij Anuj Goel Ian Ford Paul C D Johnson Toby Johnson Karen Kapur Gudmar Thorleifsson Rona J Strawbridge Laura J Rasmussen-Torvik Tõnu esko evelin Mihailov Tove Fall Ross M Fraser Anubha Mahajan Stavroula Kanoni Vilmantas Giedraitis Marcus e Kleber Günther Silbernagel Julia Meyer Martina Müller-Nurasyid Andrea Ganna Antti-Pekka Sarin Loic Yengo Dmitry Shungin Jian'an Luan Momoko Horikoshi Ping An Serena Sanna Yvonne Boettcher N William Rayner Ilja M Nolte Tatijana Zemunik erik van Iperen Peter Kovacs Nicholas D Hastie Sarah H Wild Stela McLachlan Susan Campbell Ozren Polasek Olga Carlson Josephine egan Wieland Kiess Gonneke Willemsen Johanna Kuusisto Markku Laakso Maria Dimitriou Andrew A Hicks Rainer Rauramaa Stefania Bandinelli Barbara Thorand Yongmei Liu Iva Miljkovic Lars Lind Alex Doney Markus Perola Aroon Hingorani Mika Kivimaki Meena Kumari Amanda J Bennett Christopher J Groves Christian Herder Heikki A Koistinen Leena Kinnunen Ulf de Faire Stephan J L Bakker Matti Uusitupa Colin N A Palmer J Wouter Jukema Naveed Sattar Anneli Pouta Harold Snieder eric Boerwinkle James S Pankow Patrik K Magnusson Ulrika Krus Chiara Scapoli eco J C N de Geus Matthias Blüher Bruce H R Wolffenbuttel Michael A Province Goncalo R Abecasis James B Meigs G Kees Hovingh Jaana Lindström James F Wilson Alan F Wright George V Dedoussis Stefan R Bornstein Peter e H Schwarz Anke Tönjes Bernhard R Winkelmann Bernhard O Boehm Winfried März Andres Metspalu Jackie F Price Panos Delouk Wellcome Centre for Human Genetics University of Oxford Oxford UK. Department of Microbiology and Immunology Laboratory of Adaptive Immunity KU Leuven Leuven Belgium. VIB-KU Leuven Center for Brain and Disease Research Leuven Belgium. Estonian Genome Centre Institute of Genomics University of Tartu Tartu Estonia. Department of Biological Psychology Vrije Universiteit Amsterdam The Netherlands. Amsterdam Public Health Research Institute VU University medical center Amsterdam The Netherlands. Research Unit of Molecular Epidemiology Institute of Epidemiology Helmholtz Zentrum München Research Center for Environmental Health Neuherberg Germany. German Center for Diabetes Research (DZD München-Neuherberg Germany. MRC Epidemiology Unit University of Cambridge School of Clinical Medicine Cambridge UK. University of Lille Nord de France Lille France. CNRS UMR8199 Institut Pasteur de Lille Lille France. INSERM U970 Paris Cardiovascular Research Center PARCC 75006 Paris France. Department of Life Sciences and Biotechnology University of Ferrara Ferrara Italy. Boston University Data Coordinating Center Boston MA USA. Department of Psychiatry VU University Medical Center Amsterdam The Netherlands. MRC Integrative Epidemiology Unit University of Bristol Bristol UK. Bristol Medical School University of Bristol Bristol UK. Institute for Bioinnovation Biomedical Sciences Research Center Al. Fleming Vari Greece. Department of Medicine Imperial College London London UK. Cardiovascular Medicine Unit Center for Molecular Medicine Department of Medicine Karolinska Institutet Stockholm Karolinska University Hospital Solna Sweden. Institute for Molecular Bioscience The University of Queensland Brisbane QLD 4072 Australia. Department of Epidemiology Research Statens Serum Institut Copenhagen Denmark. Université de Lorraine IGE-PCV F-54000 Nancy France. Genetic Epidemiology Unit Department of Epidemiology Erasmus Medical Center Rotterdam the Netherlands. CAR

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FANTOM5 CAGe profiles of human and mouse samples

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Scientific Data 2017年第1期4卷 170112-170121页

作者： Noguchi, Shuhei Arakawa, Takahiro Fukuda, Shiro Furuno, Masaaki Hasegawa, Akira Hori, Fumi Ishikawa-Kato, Sachi Kaida, Kaoru Kaiho, Ai Kanamori-Katayama, Mutsumi Kawashima, Tsugumi Kojima, Miki Kubosaki, Atsutaka Manabe, Ri-Ichiroh Murata, Mitsuyoshi Nagao-Sato, Sayaka Nakazato, Kenichi Ninomiya, Noriko Nishiyori-Sueki, Hiromi Noma, Shohei Saijyo, eri Saka, Akiko Sakai, Mizuho Simon, Christophe Suzuki, Naoko Tagami, Michihira Watanabe, Shoko Yoshida, Shigehiro Arner, Peter Axton, Richard A. Babina, Magda Kenneth Baillie, J. Barnett, Timothy C. Beckhouse, Anthony G. Blumenthal, Antje Bodega, Beatrice Bonetti, Alessandro Briggs, James Brombacher, Frank Carlisle, Ailsa J. Clevers, Hans C. Davis, Carrie A. Detmar, Michael Dohi, Taeko edge, B. Albert S. edinger, Matthias ehrlund, Anna ekwall, Karl endoh, Mitsuhiro enomoto, Hideki eslami, Afsaneh Fagiolini, Michela Fairbairn, Lynsey Farach-Carson, Mary C. Faulkner, Geoffrey J. Ferrai, Carmelo Fisher, Malcolm e. Forrester, Lesley M. Fujita, Rie Furusawa, Jun-Ichi Geijtenbeek, Teunis B. Gingeras, Thomas Goldowitz, Daniel Guhl, Sven Guler, Reto Gustincich, Stefano Ha, Thomas J. Hamaguchi, Masahide Hara, Mitsuko Hasegawa, Yuki Herlyn, Meenhard Heutink, Peter Hitchens, Kelly J. Hume, David A. Ikawa, Tomokatsu Ishizu, Yuri Kai, Chieko Kawamoto, Hiroshi Kawamura, Yuki I. Kempfle, Judith S. Kenna, Tony J. Kere, Juha Khachigian, Levon M. Kitamura, Toshio Klein, Sarah Peter Klinken, S. Knox, Alan J. Kojima, Soichi Koseki, Haruhiko Koyasu, Shigeo Lee, Weonju Lennartsson, Andreas MacKay-Sim, Alan Mejhert, Niklas Mizuno, Yosuke Morikawa, Hiromasa Morimoto, Mitsuru Moro, Kazuyo Morris, Kelly J. Motohashi, Hozumi Mummery, Christine L. Nakachi, Yutaka Nakahara, Fumio Nakamura, Toshiyuki Nakamura, Yukio Nozaki, Tadasuke Ogishima, Soichi Ohkura, Naganari Ohno, Hiroshi Ohshima, Mitsuhiro Okada-Hatakeyama, Mariko Okazaki, Yasushi Orlando, Valerio Ovchinnikov, Dmitry A. Passier, Robert Patrikakis, Margaret Pombo, Ana Pradhan-Bhatt, Swati Qin, Xian-Yang Rehli, Michael Rizzu, Patrizia Roy, S Division of Genomic Technologies RIKEN Center for Life Science Technologies Yokohama Kanagawa 230-0045 Japan RIKEN Omics Science Center Yokohama Kanagawa 230-0045 Japan Department of Medicine Karolinska Institutet Stockholm 14186 Sweden Karolinska University Hospital Center for Metabolism and Endocrinology Stockholm 14186 Sweden Scottish Centre for Regenerative Medicine University of Edinburgh 5 Little France Drive Edinburgh EH164UU United Kingdom Department of Dermatology and Allergy Charite University Medicine Berlin Charitéplatz 1 Berlin 10117 Germany Roslin Institute and Royal School of Veterinary Studies University of Edinburgh Edinburgh EH259RG United Kingdom Australian Infectious Diseases Research Centre University of Queensland St Lucia 4072 QLD Australia School of Chemistry and Molecular Biosciences University of Queensland St Lucia 4072 QLD Australia Bio-Rad Laboratories Pty Ltd Hercules 94547 CA United States University of Queensland Diamantina Institute University of Queensland Woolloongabba 4102 QLD Australia IRCCS Fondazione Santa Lucia Via del Fosso di Fiorano 64 Rome 00143 Italy Australian Institute for Bioengineering and Nanotechnology University of Queensland Brisbane St Lucia 4072 QLD Australia Division of Immunology Institute of Infectious Diseases and Molecular Medicine University of Cape Town Anzio Road Observatory 7925 South Africa Immunology of Infectious Diseases Faculty of Health Sciences South African Medical Research Council University of Cape Town Anzio Road 7925 South Africa International Centre for Genetic Engineering and Biotechnology Cape Town Component Anzio Road 7925 South Africa Hubrecht Institute Royal Netherlands Academy of Arts and Sciences Uppsalalaan 8 3584 Netherlands University Medical Centre Utrecht Postbus 85500 Utrecht 3508 Netherlands Genomics Cold Spring Harbor Laboratory Cold Spring Harbor New York 11797 NY United States Institute of Pharmaceutical Sciences ETH Zurich Vladi

In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGe (Cap Analysis of Gene expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGe data production. The analysis pipeline started by measuring RNA extracts to assess their quality, and continued to CAGe library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGe profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.

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Cosmic-ray electron-positron spectrum from 7 GeV to 2 TeV with the Fermi Large Area Telescope

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Physical Review D 2017年第8期95卷 082007-082007页

作者： S. Abdollahi M. Ackermann M. Ajello W. B. Atwood L. Baldini G. Barbiellini D. Bastieri R. Bellazzini e. D. Bloom R. Bonino T. J. Brandt J. Bregeon P. Bruel R. Buehler R. A. Cameron R. Caputo M. Caragiulo D. Castro e. Cavazzuti C. Cecchi A. Chekhtman S. Ciprini J. Cohen-Tanugi F. Costanza A. Cuoco S. Cutini F. D’Ammando F. de Palma R. Desiante S. W. Digel N. Di Lalla M. Di Mauro L. Di Venere P. S. Drell A. Drlica-Wagner C. Favuzzi W. B. Focke S. Funk P. Fusco F. Gargano D. Gasparrini N. Giglietto F. Giordano M. Giroletti D. Green L. Guillemot S. Guiriec A. K. Harding T. Jogler G. Jóhannesson T. Kamae M. Kuss G. La Mura L. Latronico F. Longo F. Loparco P. Lubrano S. Maldera D. Malyshev A. Manfreda M. N. Mazziotta P. F. Michelson N. Mirabal W. Mitthumsiri T. Mizuno A. A. Moiseev M. e. Monzani A. Morselli I. V. Moskalenko M. Negro e. Nuss e. Orlando D. Paneque J. S. Perkins M. Pesce-Rollins F. Piron G. Pivato T. A. Porter G. Principe S. Rainò R. Rando M. Razzano A. Reimer O. Reimer C. Sgrò D. Simone e. J. Siskind F. Spada G. Spandre P. Spinelli H. Tajima J. B. Thayer L. Tibaldo D. F. Torres e. Troja M. Wood A. Worley G. Zaharijas S. Zimmer Department of Physical Sciences Hiroshima University Higashi-Hiroshima Hiroshima 739-8526 Japan Deutsches Elektronen Synchrotron DESY D-15738 Zeuthen Germany Department of Physics and Astronomy Clemson University Kinard Lab of Physics Clemson South Carolina 29634-0978 USA Santa Cruz Institute for Particle Physics Department of Physics and Department of Astronomy and Astrophysics University of California at Santa Cruz Santa Cruz California 95064 USA Università di Pisa and Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy Istituto Nazionale di Fisica Nucleare Sezione di Trieste I-34127 Trieste Italy Dipartimento di Fisica Università di Trieste I-34127 Trieste Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova I-35131 Padova Italy Dipartimento di Fisica e Astronomia “G. Galilei ” Università di Padova I-35131 Padova Italy Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy W. W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics and SLAC National Accelerator Laboratory Stanford University Stanford California 94305 USA Istituto Nazionale di Fisica Nucleare Sezione di Torino I-10125 Torino Italy Dipartimento di Fisica Università degli Studi di Torino I-10125 Torino Italy NASA Goddard Space Flight Center Greenbelt Maryland 20771 USA Laboratoire Univers et Particules de Montpellier Université Montpellier CNRS/IN2P3 F-34095 Montpellier France Laboratoire Leprince-Ringuet École polytechnique CNRS/IN2P3 F-91128 Palaiseau France Dipartimento di Fisica “M. Merlin” dell’Università e del Politecnico di Bari I-70126 Bari Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari I-70126 Bari Italy Agenzia Spaziale Italiana (ASI) Science Data Center I-00133 Roma Italy Istituto Nazionale di Fisica Nucleare Sezione di Perugia I-06123 Perugia Italy Dipartimento di Fisica Università degli Studi di Perugia I-06123 Perugia Italy College of Science

We present a measurement of the cosmic-ray electron+positron spectrum between 7 GeV and 2 TeV performed with almost seven years of data collected with the Fermi Large Area Telescope. We find that the spectrum is well fit by a broken power law with a break energy at about 50 GeV. Above 50 GeV, the spectrum is well described by a single power law with a spectral index of 3.07±0.02(stat+syst)±0.04(energy measurement). An exponential cutoff lower than 1.8 TeV is excluded at 95% CL.

关键词： Cosmic ray & astroparticle detectors Cosmic ray composition & spectra Cosmic ray sources Particle astrophysics

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Dirichlet-tree distribution enhanced random forests for head pose estimation

Dirichlet-tree distribution enhanced random forests for head...

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3rd International Conference on Pattern Recognition Applications and Methods, ICPRAM 2014

作者： Liu, Yuanyuan Chen, Jingying Liu, Leyuan Gong, Yujiao Luo, Nan National Engineering Research Center for E-Learning Central China Normal University Wuhan China Wuhan China Science and Technology Wenhua College Huazhong University Wuhan China

ISBN: (纸本)9789897580185

Head pose estimation is important in human-machine interfaces. However, illumination variation, occlusion and low image resolution make the estimation task difficult. Hence, a Dirichlet-tree distribution enhanced Random Forests approach (D-RF) is proposed in this paper to estimate head pose efficiently and robustly under various conditions. First, Gabor features of the facial positive patches are extracted to eliminate the influence of occlusion and noise. Then, the D-RF is proposed to estimate the head pose in a coarse-to-fine way. In order to improve the discrimination capability of the approach, an adaptive Gaussian mixture model is introduced in the tree distribution. The proposed method has been evaluated with different data sets spanning from -90° to 90° in vertical and horizontal directions under various conditions. The experimental results demonstrate the approach's robustness and efficiency. Copyright © 2014 SCITePReSS.

关键词： Image resolution

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Continuum reverberation mapping of the accretion disks in two Seyfert 1 galaxies

arXiv

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arXiv 2018年

作者： Fausnaugh, M.M. Starkey, D.A. Horne, Keith Kochanek, C.S. Peterson, B.M. Bentz, M.C. Denney, K.D. Grier, C.J. Grupe, D. Pogge, R.W. Rosa, G.D.e. Adams, S.M. Barth, A.J. Beatty, Thomas G. Bhattacharjee, A. Borman, G.A. Boroson, T.A. Bottorff, M.C. Brown, Jacob e. Brown, Jonathan S. Brotherton, M.S. Coker, C.T. Crawford, S.M. Croxall, K.V. eftekharzadeh, Sarah eracleous, Michael Joner, M.D. Henderson, C.B. Holoien, T.W.-S. Hutchison, T. Kaspi, Shai Kim, S. King, Anthea L. Miao, L.I. Lochhaas, Cassandra Zhiyuan, M.A. Macinnis, F. Manne-Nicholas, e.R. Mason, M. Montuori, Carmen Mosquera, Ana Mudd, Dale Musso, R. Nazarov, S.V. Nguyen, M.L. Okhmat, D.N. Onken, Christopher A. Ou-Yang, B. Pancoast, A. Pei, L. Penny, Matthew T. Poleski, Radoslaw Rafter, Stephen Romero-Colmenero, e. Runnoe, Jessie Sand, David J. Schimoia, Jaderson S. Sergeev, S.G. Shappee, B.J. Simonian, Gregory V. Somers, Garrett Spencer, M. Stevens, Daniel J. Tayar, Jamie Treu, T. Valenti, Stefano van Saders, J. Villanueva, S. Villforth, C. Weiss, Yaniv Winkler, H. Zhu, W. Department of Astronomy Ohio State University 140 W 18th Ave ColumbusOH43210 United States MIT Kavli Institute for Astrophysics and Space Research 77 Massachusetts Avenue 37-241 CambridgeMA02139 United States SUPA Physics and Astronomy University of St. Andrews FifeKY16 9SS Scotland United Kingdom Center for Cosmology and AstroParticle Physics Ohio State University 191 West Woodruff Ave ColumbusOH43210 United States Space Telescope Science Institute 3700 San Martin Drive BaltimoreMD21218 United States Department of Physics and Astronomy Georgia State University AtlantaGA30303 United States Illumination Works LLC. 5650 Blazer Parkway Suite 152 DublinOH43017 Department of Astronomy & Astrophysics Pennsylvania State University 525 Davey Laboratory University ParkPA16802 United States Institute for Gravitation and the Cosmos Pennsylvania State University University ParkPA16802 United States Department of Earth and Space Sciences Morehead State University MoreheadKY United States Cahill Center for Astrophysics California Institute of Technology PasadenaCA91125 United States Department of Physics and Astronomy 4129 Frederick Reines Hall University of California IrvineCA92697 United States Center for Exoplanets and Habitable Worlds Pennsylvania State University 525 Davey Lab University ParkPA16802 United States Department of Physics and Astronomy University of Wyoming 1000 E. University Ave LaramieWY United States Department of Biology Geology and Physical Sciences Sul Ross State University WSB 216 Box-64 AlpineTX79832 United States Crimean Astrophysical Observatory P/O Nauchny Crimea298409 Russia Las Cumbres Global Telescope Network 6740 Cortona Drive Suite 102 Santa BarbaraCA93117 United States Fountainwood Observatory Department of Physics FJS 149 Southwestern University 1011 E. University Ave. GeorgetownTX78626 United States Department of Physics and Astronomy University of Missouri Columbia United States South Afr

We present optical continuum lags for two Seyfert 1 galaxies, MCG+08-11-011 and NGC 2617, using monitoring data from a reverberation mapping campaign carried out in 2014. Our light curves span the ugriz filters over four months, with median cadences of 1.0 and 0.6 days for MCG+08-11-011 and NGC 2617, respectively, combined with roughly daily X-ray and near-UV data from Swift for NGC 2617. We find lags consistent with geometrically thin accretion-disk models that predict a lag-wavelength relation of τ ∝ λ4/3. However, the observed lags are larger than predictions based on standard thin-disk theory by factors of 3.3 for MCG+08-11-011 and 2.3 for NGC 2617. These differences can be explained if the mass accretion rates are larger than inferred from the optical luminosity by a factor of 4.3 in MCG+08-11-011 and a factor of 1.3 in NGC 2617, although uncertainty in the SMBH masses determines the significance of this result. While the X-ray variability in NGC 2617 precedes the UV/optical variability, the long 2.6 day lag is problematic for coronal reprocessing models. Copyright © 2018, The Authors. All rights reserved.

关键词： Galaxies

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Search for extended sources in the galactic plane using 6 years of Fermi-Large area telescope pass 8 data above 10 GeV

arXiv

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arXiv 2017年

作者： Ackermann, M. Ajello, M. Baldini, L. Ballet, J. Barbiellini, G. Bastieri, D. Bellazzini, R. Bissaldi, e. Bloom, e.D. Bonino, R. Bottacini, e. Brandt, T.J. Bregeon, J. Bruel, P. Buehler, R. Cameron, R.A. Caragiulo, M. Caraveo, P.A. Castro, D. Cavazzuti, e. Cecchi, C. Charles, e. Chekhtman, A. Cheung, C.C. Chiaro, G. Ciprini, S. Cohen, J.M. Costantin, D. Costanza, F. Cutini, S. D’Ammando, F. de Palma, F. Desiante, R. Digel, S.W. Di Lalla, N. Di Mauro, M. Di Venere, L. Favuzzi, C. Fegan, S.J. Ferrara, e.C. Franckowiak, A. Fukazawa, Y. Funk, S. Fusco, P. Gargano, F. Gasparrini, D. Giglietto, N. Giordano, F. Giroletti, M. Green, D. Grenier, I.A. Grondin, M.-H. Guillemot, L. Guiriec, S. Harding, A.K. Hays, e. Hewitt, J.W. Horan, D. Hou, X. Jóhannesson, G. Kamae, T. Kuss, M. la Mura, G. Larsson, S. Lemoine-Goumard, M. Li, J. Longo, F. Loparco, F. Lubrano, P. Magill, J.D. Maldera, S. Malyshev, D. Manfreda, A. Mazziotta, M.N. Michelson, P.F. Mitthumsiri, W. Mizuno, T. Monzani, M.e. Morselli, A. Moskalenko, I.V. Negro, M. Nuss, e. Ohsugi, T. Omodei, N. Orienti, M. Orlando, e. Ormes, J.F. Paliya, V.S. Paneque, D. Perkins, J.S. Persic, M. Pesce-Rollins, M. Petrosian, V. Piron, F. Porter, T.A. Principe, G. Rainò, S. Rando, R. Razzano, M. Razzaque, S. Reimer, A. Reimer, O. Reposeur, T. Sgrò, C. Simone, D. Siskind, e.J. Spada, F. Spandre, G. Spinelli, P. Suson, D.J. Tak, D. Thayer, J.B. Thompson, D.J. Torres, D.F. Tosti, G. Troja, e. Vianello, G. Wood, K.S. Wood, M. Deutsches Elektronen Synchrotron DESY ZeuthenD-15738 Germany Department of Physics and Astronomy Clemson University Kinard Lab of Physics ClemsonSC29634-0978 United States Università di Pisa Istituto Nazionale di Fisica Nucleare Sezione di Pisa PisaI-56127 Italy Laboratoire AIM CEA-IRFU CNRS Université Paris Diderot Service d’Astrophysique CEA Saclay Gif sur YvetteF-91191 France Istituto Nazionale di Fisica Nucleare Sezione di Trieste TriesteI-34127 Italy Dipartimento di Fisica Università di Trieste TriesteI-34127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova PadovaI-35131 Italy Dipartimento di Fisica e Astronomia "G. Galilei" Università di Padova PadovaI-35131 Italy Istituto Nazionale di Fisica Nucleare Sezione di Pisa PisaI-56127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari BariI-70126 Italy W. W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics SLAC National Accelerator Laboratory Stanford University StanfordCA94305 United States Istituto Nazionale di Fisica Nucleare Sezione di Torino TorinoI-10125 Italy Dipartimento di Fisica Università degli Studi di Torino TorinoI-10125 Italy NASA Goddard Space Flight Center GreenbeltMD20771 United States Laboratoire Univers et Particules de Montpellier Université Montpellier CNRS/IN2P3 MontpellierF-34095 France Laboratoire Leprince-Ringuet École polytechnique CNRS/IN2P3 PalaiseauF-91128 France Dipartimento di Fisica "M. Merlin" dell’Università e del Politecnico di Bari BariI-70126 Italy INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica Milano via E. Bassini 15 MilanoI-20133 Italy Science Data Center RomaI-00133 Italy Istituto Nazionale di Fisica Nucleare Sezione di Perugia PerugiaI-06123 Italy Dipartimento di Fisica Università degli Studi di Perugia PerugiaI-06123 Italy College of Science George Mason University Fairfax VA22030 United States Naval Research Laboratory Washi

The spatial extension of a γ-ray source is an essential ingredient to determine its spectral properties as well as its potential multi-wavelength counterpart. The capability to spatially resolve γ-ray sources is greatly improved by the newly delivered Fermi-Large Area Telescope (LAT) Pass 8 event-level analysis which provides a greater acceptance and an improved point spread function, two crucial factors for the detection of extended sources. Here, we present a complete search for extended sources located within 7◦ from the Galactic plane, using 6 years of Fermi-LAT data above 10 GeV. We find 46 extended sources and provide their morphological and spectral characteristics. This constitutes the first catalog of hard Fermi-LAT extended sources, named the Fermi Galactic extended Source Catalog, which allows a thorough study of the properties of the Galactic plane in the sub-TeV domain. Copyright © 2017, The Authors. All rights reserved.

关键词： Gamma rays

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Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers Abstracts

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FLUIDS AND BARRIeRS OF THe CNS 2017年第SUPPL 2期14卷 27-27页

作者： [Anonymous] The Jerzy Kukuczka Academy of Physical Education Katowice Poland The Institute of Animal Physiology and Food Research Polish Academy of Sciences Olsztyn Poland University of Miami Miami FL USA Institute of Pharmaceutical Science King’s College London London United Kingdom Department of Ophthalmology and Molecular and Integrative Physiology The University of Michigan Ann Arbor MI USA Department of Internal Medicine and Cardiology The University of Michigan Ann Arbor MI USA School of Medicine Department of Cellular and Molecular Medicine Koc University Istanbul Turkey Department of Cellular and Molecular Medicine Medical Faculty Koc University Istanbul Turkey Department of Neuroscience School of Medicine Koc University Istanbul Turkey Department of Neuroscience Medical Faculty Koc University Istanbul Turkey Department of Laboratory Animals Science Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey Department of Neuroscience Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey School of Medicine Koc University Istanbul Turkey Department of Forensic Science Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Histology and Embryology School of Medicine Koc University Istanbul Turkey Department of Histology and Embryology Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Physiology School of Medicine Koc University Istanbul Turkey Theodor Kocher Institute University of Bern Bern Switzerland Institute of Veterinary Physiology Vetsuisse Faculty University of Zurich Zurich Switzerland Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Zurich Center of Integrative Human Physiology University of Zurich Zurich Switzerland Institute for Veterinary Physiology and Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Institute of Veterinary Physiology Univer

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OBSeRVATIONS OF M31 AND M33 WITH THe FeRMI LARGe AReA TeLeSCOPe: A GALACTIC CeNTeR eXCeSS IN ANDROMeDA?

arXiv

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arXiv 2017年

作者： Ackermann, M. Ajello, M. Albert, A. Baldini, L. Ballet, J. Barbiellini, G. Bastieri, D. Bellazzini, R. Bissaldi, e. Bloom, e.D. Bonino, R. Bottacini, e. Brandt, T.J. Bregeon, J. Bruel, P. Buehler, R. Cameron, R.A. Caputo, R. Caragiulo, M. Caraveo, P.A. Cavazzuti, e. Cecchi, C. Charles, e. Chekhtman, A. Chiaro, G. Ciprini, S. Costanza, F. Cutini, S. D’Ammando, F. de Palma, F. Desiante, R. Digel, S.W. Di Lalla, N. Di Mauro, M. Di Venere, L. Favuzzi, C. Funk, S. Fusco, P. Gargano, F. Giglietto, N. Giordano, F. Giroletti, M. Glanzman, T. Green, D. Grenier, I.A. Guillemot, L. Guiriec, S. Hayashi, K. Hou, X. Jóhannesson, G. Kamae, T. Knödlseder, J. Kong, A.K.H. Kuss, M. la Mura, G. Larsson, S. Latronico, L. Li, J. Longo, F. Loparco, F. Lubrano, P. Maldera, S. Malyshev, D. Manfreda, A. Martin, P. Mazziotta, M.N. Michelson, P.F. Mirabal, N. Mitthumsiri, W. Mizuno, T. Monzani, M.e. Morselli, A. Moskalenko, I.V. Negro, M. Nuss, e. Ohsugi, T. Omodei, N. Orlando, e. Ormes, J.F. Paneque, D. Persic, M. Pesce-Rollins, M. Piron, F. Porter, T.A. Principe, G. Rainò, S. Rando, R. Razzano, M. Reimer, O. Sánchez-Conde, M. Sgrò, C. Simone, D. Siskind, e.J. Spada, F. Spandre, G. Spinelli, P. Tanaka, K. Tibaldo, L. Torres, D.F. Troja, e. Uchiyama, Y. Wang, J.C. Wood, K.S. Wood, M. Zaharijas, G. Zhou, M. Deutsches Elektronen Synchrotron DESY ZeuthenD-15738 Germany Department of Physics and Astronomy Clemson University Kinard Lab of Physics ClemsonSC29634-0978 United States Los Alamos National Laboratory Los AlamosNM87545 United States Università di Pisa Istituto Nazionale di Fisica Nucleare Sezione di Pisa PisaI-56127 Italy Laboratoire AIM CEA-IRFU CNRS Université Paris Diderot Service d’Astrophysique CEA Saclay Gif sur YvetteF-91191 France Istituto Nazionale di Fisica Nucleare Sezione di Trieste TriesteI-34127 Italy Dipartimento di Fisica Università di Trieste TriesteI-34127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova PadovaI-35131 Italy Dipartimento di Fisica e Astronomia "G. Galilei" Università di Padova PadovaI-35131 Italy Istituto Nazionale di Fisica Nucleare Sezione di Pisa PisaI-56127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari BariI-70126 Italy W. W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics SLAC National Accelerator Laboratory Stanford University StanfordCA94305 United States Istituto Nazionale di Fisica Nucleare Sezione di Torino TorinoI-10125 Italy Dipartimento di Fisica Università degli Studi di Torino TorinoI-10125 Italy NASA Goddard Space Flight Center GreenbeltMD20771 United States Laboratoire Univers et Particules de Montpellier Université Montpellier CNRS/IN2P3 MontpellierF-34095 France Laboratoire Leprince-Ringuet École polytechnique CNRS/IN2P3 PalaiseauF-91128 France Santa Cruz Institute for Particle Physics Department of Physics Department of Astronomy and Astrophysics University of California at Santa Cruz Santa CruzCA95064 United States Dipartimento di Fisica "M. Merlin" dell’Università e del Politecnico di Bari BariI-70126 Italy INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica Milano via E. Bassini 15 MilanoI-20133 Italy Science Data Center RomaI-00133 Italy Istituto Nazionale di Fi

The Fermi Large Area Telescope (LAT) has opened the way for comparative studies of cosmic rays (CRs) and high-energy objects in the Milky Way (MW) and in other, external, star-forming galaxies. Using 2 yr of observations with the Fermi LAT, Local Group galaxy M31 was detected as a marginally extended gamma-ray source, while only an upper limit has been derived for the other nearby galaxy M33. We revisited the gamma-ray emission in the direction of M31 and M33 using more than 7 yr of LAT Pass 8 data in the energy range 0.1−100 GeV, presenting detailed morphological and spectral analyses. M33 remains undetected, and we computed an upper limit of 2.0×10−12 erg cm−2 s−1 on the 0.1−100 GeV energy flux (95% confidence level). This revised upper limit remains consistent with the observed correlation between gamma-ray luminosity and star-formation rate tracers and implies an average CR density in M33 that is at most half of that of the MW. M31 is detected with a significance of nearly 10σ. Its spectrum is consistent with a power law with photon index Γ = 2.4±0.1stat+syst and a 0.1−100 GeV energy flux of (5.6±0.6stat+syst)×10−12 erg cm−2 s−1. M31 is detected to be extended with a 4σ significance. The spatial distribution of the emission is consistent with a uniform-brightness disk with a radius of 0◦.4 and no offset from the center of the galaxy, but nonuniform intensity distributions cannot be excluded. The flux from M31 appears confined to the inner regions of the galaxy and does not fill the disk of the galaxy or extend far from it. The gamma-ray signal is not correlated with regions rich in gas or star-formation activity, which suggests that the emission is not interstellar in origin, unless the energetic particles radiating in gamma rays do not originate in recent star formation. Alternative and nonexclusive interpretations are that the emission results from a population of millisecond pulsars dispersed in the bulge and disk of M31 by disrupted globular clusters or from

关键词： Galaxies

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Abstracts and Workshops 7th national Spinal Cord Injury Conference November 9-11, 2017 Fallsview Casino Resort Niagara Falls, Ontario, Canada Abstracts

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JOURNAL OF SPINAL CORD MeDICINe 2017年第6期40卷 813-869页

作者： [Anonymous] a NET Team Toronto Rehabilitation Institute - University Health Network Toronto ON Canada. fo Neural Engineering and Therapeutic Team Lyndhurst Centre Toronto Rehabilitation Institute - University Health Network Toronto ON Canada. c Rick Hansen Institute Vancouver BC Canada. ev Rick Hansen Institute Vancouver BC Canada. fc Stan Cassidy Hospital University of New Brunswick Fredericton NB Canada. fd Dalhousie University Halifax NS Canada. e University of Saskatchewan Saskatoon SK Canada. aa University of Calgary Calgary AB Canada. y Dalhousie University Halifax NS Canada. fa Health Sciences Centre Winnipeg MB Canada. fb University of Manitoba Winnipeg MB Canada. h University of Alberta Edmonton AB Canada. i Universite Laval Quebe c City QC Canada. bd Rick Hansen Institute Vancouver BC Canada. fz Clinician Investigator Lyndhurst Centre Toronto Rehabilitation Institute University Health Network and Assistant Professor Department of Medicine Division of Physical Medicine and Rehabilitation University of Toronto. v University of Toront o Toronto ON Canada. n Institute of Biomaterials and Biomedical Engineering University of Toronto Toronto ON Canada. o Toronto Rehabilitation Institute - University Health Network Toronto ON Canada. ga Clinical Scientist Lyndhurst Centre Toronto Rehabilitation Institute University Health Network and Assistant Professor Department of Physical Therapy University of Toronto. dx Department of Electrical and Computer Engineering University of Toronto Toronto ON Canada. fm Lawson Health Research Institute London ON Canada. r Parkwood Institute London ON Canada. bi Parkwood Institute London ON Canada. s University of British Columbia Vancouver BC Canada. t Simon Fraser University Burnaby BC Canada. u DeltaQuest Foundation Concord MA USA. z Institut national d'excellence en santé et en services sociaux (INESSS) Quebec City QC Ca

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Fermi-lat observations of high-energy behind-the-limb solar flares

arXiv

引用

arXiv 2017年

作者： Ackermann, M. Allafort, A. Baldini, L. Barbiellini, G. Bastieri, D. Bellazzini, R. Bissaldi, e. Bonino, R. Bottacini, e. Bregeon, J. Bruel, P. Buehler, R. Cameron, R.A. Caragiulo, M. Caraveo, P.A. Cavazzuti, e. Cecchi, C. Charles, e. Ciprini, S. Costanza, F. Cutini, S. D'Ammando, F. de Palma, F. Desiante, R. Digel, S.W. Di Lalla, N. Di Mauro, M. Di Venere, L. Drell, P.S. Favuzzi, C. Fukazawa, Y. Fusco, P. Gargano, F. Giglietto, N. Giordano, F. Giroletti, M. Grenier, I.A. Guillemot, L. Guiriec, S. Jogler, T. Jóhannesson, G. Kashapova, L. Krucker, S. Kuss, M. la Mura, G. Larsson, S. Latronico, L. Li, J. Liu, W. Longo, F. Loparco, F. Lubrano, P. Magill, J.D. Maldera, S. Manfreda, A. Mazziotta, M.N. Mitthumsiri, W. Mizuno, T. Monzani, M.e. Morselli, A. Moskalenko, I.V. Negro, M. Nuss, e. Ohsugi, T. Omodei, N. Orlando, e. Pal'shin, V. Paneque, D. Perkins, J.S. Pesce-Rollins, M. Petrosian, V. Piron, F. Principe, G. Rainò, S. Rando, R. Razzano, M. Reimer, O. Rubio da Costa, F. Sgrò, C. Simone, D. Siskind, e.J. Spada, F. Spandre, G. Spinelli, P. Tajima, H. Thayer, J.B. Torres, D.F. Troja, e. Vianello, G. Deutsches Elektronen Synchrotron DESY ZeuthenD-15738 Germany W. W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics SLAC National Accelerator Laboratory Stanford University StanfordCA94305 United States Università di Pisa Istituto Nazionale di Fisica Nucleare Sezione di Pisa PisaI-56127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Trieste TriesteI-34127 Italy Dipartimento di Fisica Università di Trieste TriesteI-34127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova PadovaI-35131 Italy Dipartimento di Fisica e Astronomia "G. Galilei" Università di Padova PadovaI-35131 Italy Istituto Nazionale di Fisica Nucleare Sezione di Pisa PisaI-56127 Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari BariI-70126 Italy Istituto Nazionale di Fisica Nucleare Sezione di Torino TorinoI-10125 Italy Dipartimento di Fisica Università degli Studi di Torino TorinoI-10125 Italy Laboratoire Univers et Particules de Montpellier Université Montpellier CNRS IN2P3 MontpellierF-34095 France Laboratoire Leprince-Ringuet École polytechnique CNRS IN2P3 PalaiseauF-91128 France Dipartimento di Fisica "M. Merlin" dell'Università e del Politecnico di Bari BariI-70126 Italy INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica Milano via E. Bassini 15 MilanoI-20133 Italy Science Data Center RomaI-00133 Italy Istituto Nazionale di Fisica Nucleare Sezione di Perugia PerugiaI-06123 Italy Dipartimento di Fisica Università degli Studi di Perugia PerugiaI-06123 Italy INAF Istituto di Radioastronomia BolognaI-40129 Italy Dipartimento di Astronomia Università di Bologna BolognaI-40127 Italy Università Telematica Pegaso Piazza Trieste e Trento 48 NapoliI-80132 Italy Università di Udine UdineI-33100 Italy Department of Physical Sciences Hiroshima University Higashi-Hiroshima Hiroshima739-8526 Japan Laboratoire AIM CEA IRFU CNRS Université Paris Diderot Servic

We report on the Fermi-LAT detection of high-energy emission from the behind-the-limb solar flares that occurred on 2013 October 11, 2014 January 6 and 2014 September 1. The Fermi-LAT observations are associated with flares from active regions originating behind both the eastern and western limbs, as determined by STeReO. All three flares are associated with very fast Coronal Mass ejections (CMes) and strong Solar energetic Particle events. We present updated localizations of the > 100 MeV photon emission, hard X-ray (HXR) and eUV images and broad-band spectra from 10 keV to 10 GeV as well as microwave spectra. We also provide a comparison of the behind-the-limb flares detected by the Fermi-LAT with three on-disk flares and present a study of some of the significant quantities of these flares as an attempt to better understand the acceleration mechanisms at work during these occulted flares. We interpret the HXR emission to be due to electron bremsstrahlung from a coronal thin-target loop-top with the accelerated electron spectra steepening at semirelativistic energies. The > 100 MeV gamma-rays are best described by a pion decay model resulting from interaction of protons (and other ions) in a thick target photospheric source. The protons are believed to have been accelerated (to energies > 10 GeV) in the CMe environment and precipitate down to the photosphere from the down-stream side of the CMe shock and landed on the front side of the Sun, away from the original flare site and the HXR emission. Copyright © 2017, The Authors. All rights reserved.

关键词： Gamma rays

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