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Annual business and news:: Beginning the 31st year of the Journal of Guidance, Control, and Dynamics

JOURNAL OF GUIDANCE CONTROL AND DYNAMICS 2008年第1期31卷 1-1页

作者： Schmidt, George T. Aeronautics and Astronautics Massachusetts Institute of Technology (MIT) AIAA Institute of Electrical and Electronics Engineers Russian Federation Academy of Navigation and Motion Control Department of Mechanical and Aerospace Engineering and Engineering Mechanics University of Missouri-Rolla(UMR) Lockheed Electronics Company Center for Space Research University of Texas Austin United States Wright Laboratory Eglin Air Force Base UMR AIAA Guidance Navigation and Control Technical Committee American Automatic Control Council Lockheed Martin Aeronautics Company Palmdale CA United States C4ISR and Unmanned Air Vehicle (UAV) Programs for Air Vehicle Sciences and Systems Accreditation Board Engineering and Technology Inc./Aeronautical National Technical Committee on Guidance Navigation and Control Department of Mechanical and Aerospace Engineering University at Buffalo State University of New York (SUNY) AIAA Technical Committee on GN and C Air Vehicles Directorate Air Force Research Laboratory (AFRL) Wright-Patterson Air Force Base Space Access and Hypersonic Vehicle Guidance and Control Group Control Science Center of Excellence AFRL AIAA Technical Committee on Guidance Navigation and Control Department of Mechanical and Aeronautical Engineering University of California (UC) Davis United States Boeing Company Modernized Flight Control System for the Apache Longbow AIAA Institute of Electrical and Electronics Engineers AHS Jet Propulsion Laboratory California Institute of Technology Boeing Company Flight Sciences and Advanced Design Group Guidance Navigation and Control (GN and C) Systems Engineer Distributed Space Systems NASA Goddard Space Flight Center (GSFC) AIAA GN and C Technical Committee Department of Aerospace Engineering and Engineering Mechanics University of Texas Austin United States Institute of Navigation American Astronautical Society AIAA Guidance Navigation (GN and C) and Control Technical Committee Department of Aerospace Engineering Iowa State University Iowa

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Open X-Embodiment: Robotic Learning Datasets and RT-X Models : Open X-Embodiment Collaboration0

Open X-Embodiment: Robotic Learning Datasets and RT-X Models...

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2024 IEEE International Conference on robotics and automation, ICRA 2024

作者： O'Neill, Abby Rehman, Abdul Maddukuri, Abhiram Gupta, Abhishek Padalkar, Abhishek Lee, Abraham Pooley, Acorn Gupta, Agrim Mandlekar, Ajay Jain, Ajinkya Tung, Albert Bewley, Alex Herzog, Alex Irpan, Alex Khazatsky, Alexander Rai, Anant Gupta, Anchit Wang, Andrew Singh, Anikait Garg, Animesh Kembhavi, Aniruddha Xie, Annie Brohan, Anthony Raffin, Antonin Sharma, Archit Yavary, Arefeh Jain, Arhan Balakrishna, Ashwin Wahid, Ayzaan Burgess-Limerick, Ben Kim, Beomjoon Scholkopf, Bernhard Wulfe, Blake Ichter, Brian Lu, Cewu Xu, Charles Le, Charlotte Finn, Chelsea Wang, Chen Xu, Chenfeng Chi, Cheng Huang, Chenguang Chan, Christine Agia, Christopher Pan, Chuer Fu, Chuyuan Devin, Coline Xu, Danfei Morton, Daniel Driess, Danny Chen, Daphne Pathak, Deepak Shah, Dhruv Buchler, Dieter Jayaraman, Dinesh Kalashnikov, Dmitry Sadigh, Dorsa Johns, Edward Foster, Ethan Liu, Fangchen Ceola, Federico Xia, Fei Zhao, Feiyu Stulp, Freek Zhou, Gaoyue Sukhatme, Gaurav S. Salhotra, Gautam Yan, Ge Feng, Gilbert Schiavi, Giulio Berseth, Glen Kahn, Gregory Wang, Guanzhi Su, Hao Fang, Hao-Shu Shi, Haochen Bao, Henghui Ben Amor, Heni Christensen, Henrik I Furuta, Hiroki Walke, Homer Fang, Hongjie Ha, Huy Mordatch, Igor Radosavovic, Ilija Leal, Isabel Liang, Jacky Abou-Chakra, Jad Kim, Jaehyung Drake, Jaimyn Peters, Jan Schneider, Jan Hsu, Jasmine Bohg, Jeannette Bingham, Jeffrey Wu, Jeffrey Gao, Jensen Hu, Jiaheng Wu, Jiajun Wu, Jialin Sun, Jiankai Luo, Jianlan Gu, Jiayuan Tan, Jie Oh, Jihoon Wu, Jimmy Lu, Jingpei Yang, Jingyun Malik, Jitendra Silverio, Joao Hejna, Joey Booher, Jonathan Tompson, Jonathan Yang, Jonathan Salvador, Jordi Lim, Joseph J. Han, Junhyek Wang, Kaiyuan Rao, Kanishka Pertsch, Karl Hausman, Karol Go, Keegan Gopalakrishnan, Keerthana Goldberg, Ken Byrne, Kendra Oslund, Kenneth Kawaharazuka, Kento Black, Kevin Lin, Kevin Zhang, Kevin Ehsani, Kiana Lekkala, Kiran Ellis, Kirsty Rana, Krishan Srinivasan, Krishnan Fang, Kuan Singh, Kunal Pratap Zeng, Kuo-Hao Hatch, Kyle Hsu, Kyle Itti, Laurent Chen, Lawrence Yunliang Pinto, Lerrel Allen Institute for AI United States Arizona State University United States California Institute of Technology United States Carnegie Mellon University United States Columbia University United States EPFL Switzerland ETH Zürich Switzerland Flexiv Robotics United States Georgia Institute of Technology United States German Aerospace Center Germany Google DeepMind United Kingdom Google Research United States IO-AI Tech Imperial College London United Kingdom Intrinsic Llc United States Istituto Italiano di Tecnologia Italy Korea Advanced Institute of Science & Technology Korea Republic of Max Planck Institute Germany Meta AI United States Mila Quebec Canada NVIDIA United States New York University United States Princeton University United States Queensland University of Technology Australia Riken Japan Shanghai Jiao Tong University China Stanford University United States Technische Universität Darmstadt Germany University of Texas at Austin United States University of Tokyo Japan Toyota Research Institute United States University of California Berkeley United States University of California Davis United States University of California San Diego United States University of Edinburgh United Kingdom University of Freiburg Germany University of Illinois Urbana-Champaign United States University of Michigan United States University of Montreal Canada University of Pennsylvania United States University of Southern California United States University of Technology Nuremberg Germany University of Washington United States

ISBN: (纸本)9798350384574

Large, high-capacity models trained on diverse datasets have shown remarkable successes on efficiently tackling downstream applications. In domains from NLP to Computer Vision, this has led to a consolidation of pretrained models, with general pretrained backbones serving as a starting point for many applications. Can such a consolidation happen in robotics? Conventionally, robotic learning methods train a separate model for every application, every robot, and even every environment. Can we instead train "generalist"X-robot policy that can be adapted efficiently to new robots, tasks, and environments? In this paper, we provide datasets in standardized data formats and models to make it possible to explore this possibility in the context of robotic manipulation, alongside experimental results that provide an example of effective X-robot policies. We assemble a dataset from 22 different robots collected through a collaboration between 21 institutions, demonstrating 527 skills (160266 tasks). We show that a high-capacity model trained on this data, which we call RT-X, exhibits positive transfer and improves the capabilities of multiple robots by leveraging experience from other platforms. The project website is ***. © 2024 IEEE.

关键词： Robot learning

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Open X-Embodiment: Robotic Learning Datasets and RT-X Models : Open X-Embodiment Collaboration0

Open X-Embodiment: Robotic Learning Datasets and RT-X Models...

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IEEE International Conference on robotics and automation (ICRA)

作者： Abby O’Neill Abdul Rehman Abhiram Maddukuri Abhishek Gupta Abhishek Padalkar Abraham Lee Acorn Pooley Agrim Gupta Ajay Mandlekar Ajinkya Jain Albert Tung Alex Bewley Alex Herzog Alex Irpan Alexander Khazatsky Anant Rai Anchit Gupta Andrew Wang Anikait Singh Animesh Garg Aniruddha Kembhavi Annie Xie Anthony Brohan Antonin Raffin Archit Sharma Arefeh Yavary Arhan Jain Ashwin Balakrishna Ayzaan Wahid Ben Burgess-Limerick Beomjoon Kim Bernhard Schölkopf Blake Wulfe Brian Ichter Cewu Lu Charles Xu Charlotte Le Chelsea Finn Chen Wang Chenfeng Xu Cheng Chi Chenguang Huang Christine Chan Christopher Agia Chuer Pan Chuyuan Fu Coline Devin Danfei Xu Daniel Morton Danny Driess Daphne Chen Deepak Pathak Dhruv Shah Dieter Büchler Dinesh Jayaraman Dmitry Kalashnikov Dorsa Sadigh Edward Johns Ethan Foster Fangchen Liu Federico Ceola Fei Xia Feiyu Zhao Freek Stulp Gaoyue Zhou Gaurav S. Sukhatme Gautam Salhotra Ge Yan Gilbert Feng Giulio Schiavi Glen Berseth Gregory Kahn Guanzhi Wang Hao Su Hao-Shu Fang Haochen Shi Henghui Bao Heni Ben Amor Henrik I Christensen Hiroki Furuta Homer Walke Hongjie Fang Huy Ha Igor Mordatch Ilija Radosavovic Isabel Leal Jacky Liang Jad Abou-Chakra Jaehyung Kim Jaimyn Drake Jan Peters Jan Schneider Jasmine Hsu Jeannette Bohg Jeffrey Bingham Jeffrey Wu Jensen Gao Jiaheng Hu Jiajun Wu Jialin Wu Jiankai Sun Jianlan Luo Jiayuan Gu Jie Tan Jihoon Oh Jimmy Wu Jingpei Lu Jingyun Yang Jitendra Malik João Silvério Joey Hejna Jonathan Booher Jonathan Tompson Jonathan Yang Jordi Salvador Joseph J. Lim Junhyek Han Kaiyuan Wang Kanishka Rao Karl Pertsch Karol Hausman Keegan Go Keerthana Gopalakrishnan Ken Goldberg Kendra Byrne Kenneth Oslund Kento Kawaharazuka Kevin Black Kevin Lin Kevin Zhang Kiana Ehsani Kiran Lekkala Kirsty Ellis Krishan Rana Krishnan Srinivasan Kuan Fang Kunal Pratap Singh Kuo-Hao Zeng Kyle Hatch Kyle Hsu Laurent Itti Lawrence Yunliang Chen Lerrel Pinto Li Fei-Fei Liam Tan Linxi Jim Fan Lionel Ott Lisa Lee Luca Weihs Magnum Chen Marion Lepert Marius Memmel Masayoshi Tomizuka Masha Itkina Mateo University of California Berkeley University of Edinburgh University of Texas at Austin University of Washington German Aerospace Center Google DeepMind Stanford University NVIDIA Intrinsic LLC New York University Meta AI Georgia Institute of Technology Allen Institute for AI University of California Davis Toyota Research Institute Queensland University of Technology Korea Advanced Institute of Science & Technology Max Planck Institute Shanghai Jiao Tong University Flexiv Robotics Columbia University University of Freiburg Carnegie Mellon University University of Pennsylvania Imperial College London Istituto Italiano di Tecnologia IO-AI TECH University of Southern California University of California San Diego ETH Zürich University of Montreal Mila Quebec California Institute of Technology Arizona State University The University of Tokyo Technische Universität Darmstadt The University of Texas at Austin Google Research Princeton University EPFL University of Illinois Urbana-Champaign University of Michigan RIKEN University of Technology Nuremberg

ISBN: (数字)9798350384574

ISBN: (纸本)9798350384581

Large, high-capacity models trained on diverse datasets have shown remarkable successes on efficiently tackling downstream applications. In domains from NLP to Computer Vision, this has led to a consolidation of pretrained models, with general pretrained backbones serving as a starting point for many applications. Can such a consolidation happen in robotics? Conventionally, robotic learning methods train a separate model for every application, every robot, and even every environment. Can we instead train "generalist" X-robot policy that can be adapted efficiently to new robots, tasks, and environments? In this paper, we provide datasets in standardized data formats and models to make it possible to explore this possibility in the context of robotic manipulation, alongside experimental results that provide an example of effective X-robot policies. We assemble a dataset from 22 different robots collected through a collaboration between 21 institutions, demonstrating 527 skills (160266 tasks). We show that a high-capacity model trained on this data, which we call RT-X, exhibits positive transfer and improves the capabilities of multiple robots by leveraging experience from other platforms. The project website is ***.

关键词： Learning systems Adaptation models Computer vision Computational modeling Collaboration Data models Task analysis

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25th Annual Computational Neuroscience Meeting CNS-2016, Seogwipo City, South Korea, July 2-7, 2016 Abstracts

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BMC NEUROSCIENCE 2016年第1期17卷 1-112页

作者： [Anonymous] Computational Neurobiology Laboratory The Salk Institute for Biological Studies San Diego USA UNIC CNRS Gif sur Yvette France The European Institute for Theoretical Neuroscience (EITN) Paris France ATR Computational Neuroscience Laboratories Kyoto Japan Krembil Research Institute University Health Network Toronto Canada Department of Physiology University of Toronto Toronto Canada Department of Medicine (Neurology) University of Toronto Toronto Canada Department of Physics University of New Hampshire Durham USA Department of Neurophysiology Nencki Institute of Experimental Biology Warsaw Poland Department of Theory Wigner Research Centre for Physics of the Hungarian Academy of Sciences Budapest Hungary Department of Mathematical Sciences KAIST Daejoen Republic of Korea Department of Mathematics University of Houston Houston USA Department of Biochemistry & Cell Biology and Institute of Biosciences and Bioengineering Rice University Houston USA Department of Biology and Biochemistry University of Houston Houston USA Grupo de Neurocomputación Biológica Dpto. de Ingeniería Informática Escuela Politécnica Superior Universidad Autónoma de Madrid Madrid Spain Department of Biological Sciences University of Southern California Los Angeles USA Center for Neuroscience Korea Institute of Science and Technology Seoul South Korea Department of Neurology Albert Einstein College of Medicine Bronx USA Center for Neuroscience KIST Seoul South Korea Department of Neuroscience University of Science and Technology Daejon South Korea Systems Neuroscience Group QIMR Berghofer Medical Research Institute Herston Australia Department of Psychology Yonsei University Seoul South Korea Department of Psychiatry Kyung Hee University Hospital at Gangdong Seoul South Korea Department of Psychiatry Veterans Administration Boston Healthcare System and Harvard Medical School Brockton USA Department of Electrical and Electronic Engineering The University of Melbourne Parkvil

A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Precise recruitment of spiking output at theta frequencies requires dendritic h-channels in multi-compartment models of oriens-lacunosum/moleculare hippocampal interneurons Vladislav Sekulić, Frances K. Skinner F2 Kernel methods in reconstruction of current sources from extracellular potentials for single cells and the whole brains Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári F3 The synchronized periods depend on intracellular transcriptional repression mechanisms in circadian clocks. Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić O1 Assessing irregularity and coordination of spiking-bursting rhythms in central pattern generators Irene Elices, David Arroyo, Rafael Levi, Francisco B. Rodriguez, Pablo Varona O2 Regulation of top-down processing by cortically-projecting parvalbumin positive neurons in basal forebrain Eunjin Hwang, Bowon Kim, Hio-Been Han, Tae Kim, James T. McKenna, Ritchie E. Brown, Robert W. McCarley, Jee Hyun Choi O3 Modeling auditory stream segregation, build-up and bistability James Rankin, Pamela Osborn Popp, John Rinzel O4 Strong competition between tonotopic neural ensembles explains pitch-related dynamics of auditory cortex evoked fields Alejandro Tabas, André Rupp, Emili Balaguer-Ballester O5 A simple model of retinal response to multi-electrode stimulation Matias I. Maturana, David B. Grayden, Shaun L. Cloherty, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin O6 Noise correlations in V4 area correlate with behavioral performance in visual discrimination task Veronika Koren, Timm Lochmann, Valentin Dragoi, Klaus Obermayer O7 Input-location dependent gain modulation in cerebellar nucleus neurons Maria Psarrou, Maria Schilstra, Neil Davey, Benjamin Torben-Ni

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NTIRE 2023 Challenge on Efficient Super-Resolution: Methods and Results

NTIRE 2023 Challenge on Efficient Super-Resolution: Methods ...

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2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops, CVPRW 2023

作者： Li, Yawei Zhang, Yulun Timofte, Radu Van Gool, Luc Yu, Lei Li, Youwei Li, Xinpeng Jiang, Ting Wu, Qi Han, Mingyan Lin, Wenjie Jiang, Chengzhi Luo, Jinting Fan, Haoqiang Liu, Shuaicheng Wang, Yucong Cai, Minjie Li, Mingxi Zhang, Yuhang Fan, Xian-Jun Sheng, Yankai Mao, Yanyu Zhang, Nihao Wang, Qian Zheng, Mingjun Sun, Long Pan, Jinshan Dong, Jiangxin Tang, Jinhui Yang, Zhongbao Wang, Yan Pan, Erlin Cai, Qixuan Dai, Xinan Zhussip, Magauiya Kalyazin, Nikolay Vyal, Dmitry Zou, Xueyi Yan, Youliang Chung, Heaseo Zhang, Jin Yu, Gaocheng Zhang, Feng Wang, Hongbin Liao, Bohao Du, Zhibo Wu, Yu-Liang Shi, Gege Peng, Long Wang, Yang Cao, Yang Zha, Zhengjun Huang, Zhi-Kai Chen, Yi-Chung Chiang, Yuan-Chun Yang, Hao-Hsiang Chen, Wei-Ting Chang, Hua-En Chen, I-Hsiang Hsieh, Chia-Hsuan Kuo, Sy-Yen Liu, Xin Pan, Jiahao Yu, Hongyuan Yu, Weichen Ge, Lin Dong, Jiahua Zou, Yajun Wu, Zhuoyuan Han, Binnan Zhang, Xiaolin Zhang, Heng Yin, Xuanwu Zuo, Kunlong Deng, Weijian Yuan, Hongjie Lu, Zengtong Ouyang, Mingyu Ma, Wenzhuo Liu, Nian Zheng, Hanyou Zhang, Yuantong Zhang, Junxi Chen, Zhenzhong Gendy, Garas Sabor, Nabil Hou, Jingchao He, Guanghui Zhu, Yurui Wang, Xi Fu, Xueyang Zha, Zheng-Jun Yin, Daheng Liu, Mengyang Chen, Baijun Li, Ao Luo, Lei Jin, Kangjun Zhu, Ce Zhang, Xiaoming Xie, Chengxing Li, Linze Meng, Haiteng Zhang, Tianlin Li, Tianrui Zhao, Xiaole Zhang, Zhao Li, Baiang Zheng, Huan Zhao, Suiyi Gao, Yangcheng Ren, Jiahuan Hu, Kang Shi, Jingpeng Wu, Zhijian Huang, Dingjiang Zhu, Jinchen Li, Hui Xv, Qianru Liu, Tianle Weng, Shizhuang Wu, Gang Jiang, Junpeng Liu, Xianming Jiang, Junjun Zhang, Mingjian Hu, Jing Wu, Chengxu Fan, Qinrui Feng, Chengming Luo, Ziwei Hu, Shu Lyu, Siwei Wu, Xi Wang, Xin Computer Vision Lab ETH Zurich Switzerland Computer Vision Lab University of Würzburg Germany Megvii Technology China MicroBT China College of Computer Science and Electronic Engineering Hunan University China Attrsense Xian University of Posts and Telecommunications Xi'an China National Engineering Laboratory for Cyber Event Warning and Control Technologies China Nanjing University of Science and Technology China Nankai University China University of Electronic Science and Technology of China China Tianjin University China Noah's Ark Lab Huawei Technologies McMaster University Canada Espresomedia Korea Republic of AntGroup China University of Science and Technology of China China Department of Electrical Engineering National Taiwan University Taiwan Graduate Institute of Communication Engineering National Taiwan University Taiwan Graduate Institute of Electronics Engineering National Taiwan University Taiwan ServiceNow United States China Mobile Research Institute China Chongqing University of Technology China Multimedia Department Xiaomi Inc. China Institute of Automation Chinese Academy of Sciences China Shenyang Institute of Automation Chinese Academy of Sciences China School of Information and Communication Engineering Communication University of China China Smart Classroom Division Ruijie Networks Co. Ltd. China School of Remote Sensing and Information Engineering Wuhan University China Micro-Nano Electronics Department Shanghai Jiao Tong University Shanghai200240 China Electrical Engineering Department Faculty of Engineering Assiut University Assiut71516 Egypt Southeast University China University of Electronic Science and Technology of China Chengdu China Chongqing University of Posts and Telecommunications Chongqing China Information Technology Co. Ltd Hangzhou China Southwest Jiaotong University China National Space Science Center Chinese Academy of Science China Hefei University of Technology Hefei China Anhui University China Fried Ric

ISBN: (纸本)9798350302493

This paper reviews the NTIRE 2023 challenge on efficient single-image super-resolution with a focus on the proposed solutions and results. The aim of this challenge is to devise a network that reduces one or several aspects such as runtime, parameters, FLOPs, activations, memory footprint, and depth of RFDN while at least maintaining the PSNR of 29.00dB on DIV2K validation datasets. The challenge had 272 registered participants, and 35 teams made valid submissions. They gauge the state-of-the-art for efficient single-image super-resolution. © 2023 IEEE.

关键词： Optical resolving power

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Foreword

Proceedings of the 2016 International Conference on Image Pr...

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Proceedings of the 2016 International Conference on Image Processing, Computer Vision, and Pattern Recognition, IPCV 2016 2016年

作者： Abd-Wahab, Mohd Helmy Al-Bakry, Abbas Al-Holou, Nizar Arabnia, Hamid R. Bhattacharya, Mahua Martinez Castillo, Juan Jose Daimi, Kevin Deligiannidis, Leonidas Djoudi, Lamia Atma Duong, Trung Eshaghian-Wilner, Mary Mehrnoosh Gravvanis, George A. Huang, Ruizhu Jandieri, George Kim, Byung-Gyu Kim, Tai-hoon Korovin, Iakov Lai, Guoming Lee, Hyo Jong Bin Mansor, Muhammad Naufal Marsh, Andrew Mostafaeipour, Ali Park, James J. Patil, Shashikant Ponalagusamy, R. Schaefer, Gerald Singh, Akash Solo, Ashu M.G. Swee, Sim Kok Thomas, Jaya Tinetti, Fernando G. Vladimir, Hahanov Wang, Shiuh-Jeng Yang, Mary Yoe, Hyun You, Jane Zhao, Wenbing Department of Computer Engineering University Tun Hussein Onn Malaysia Malaysia University of IT and Communications Baghdad Iraq Electrical and Computer Engineering Department IEEE/SEM-Computer Chapter University of Detroit Mercy DetroitMI United States University of Georgia United States ABV Indian Institute of Information Technology and Management MHRD Government of India India Acantelys Alan Turing Nikola Tesla Research Group and GIPEB Universidad Nacional Abierta Venezuela Computer Science and Software Engineering Programs Department of Mathematics Computer Science and Software Engineering University of Detroit Mercy DetroitMI United States Department of Computer Information Systems Wentworth Institute of Technology BostonMA United States Synchrone Technologies France Rutgers University State University of New Jersey New Jersey United States University of Southern California California United States Electrical Engineering University of California Los Angeles Los Angeles [UCLA CA United States Advanced Scientific Computing Applied Math and Applications Research Group Applied Mathematics and Numerical Computing and Department of ECE School of Engineering Democritus University of Thrace Xanthi Greece Texas Advanced Computing Center University of Texas AustinTX United States Georgian Technical University Tbilisi Georgia Institute of Cybernetics Georgian Academy of Science Georgia Multimedia Processing CommunicationsLab.[MPCL Department of Computer Science and Engineering College of Engineering SunMoon University Korea Republic of School of Information and Computing Science University of Tasmania Australia Southern Federal University Russia Computer Science and Technology Sun Yat-Sen University Guangzhou China Center for Advanced Image and Information Technology Division of Computer Science and Engineering Chonbuk National University Korea Republic of Faculty of Engineering Technology Kampus Uniciti Alam Universiti Malaysia Perlis UniMAP Malaysi

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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (vol 51, pg 659, 2019)

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NATURE GENETICS 2019年第6期51卷 1068-1068页

作者： Huckins, Laura M. Dobbyn, Amanda Ruderfer, Douglas M. Hoffman, Gabriel Wang, Weiqing Pardinas, Antonio F. Rajagopal, Veera M. Als, Thomas D. Nguyen, Hoang T. Girdhar, Kiran Boocock, James Roussos, Panos Fromer, Menachem Kramer, Robin Domenici, Enrico Gamazon, Eric R. Purcell, Shaun Demontis, Ditte Borglum, Anders D. Walters, James T. R. O'Donovan, Michael C. Sullivan, Patrick Owen, Michael J. Devlin, Bernie Sieberts, Solveig K. Cox, Nancy J. Im, Hae Kyung Sklar, Pamela Stahl, Eli A. Pamela Sklar Division of Psychiatric Genomics Icahn School of Medicine at Mount Sinai New York NY USA Department of Genetics and Genomics Icahn School of Medicine at Mount Sinai New York NY USA Department of Psychiatry Icahn School of Medicine at Mount Sinai New York NY USA Icahn Institute for Genomics and Multiscale Biology Icahn School of Medicine at Mount Sinai New York NY USA Vanderbilt University Medical Center Nashville TN USA MRC Centre for Neuropsychiatric Genetics and Genomics Cardiff University Cardiff UK Department of Biomedicine Aarhus University Aarhus Denmark The Lundbeck Foundation Initiative for Integrative Psychiatric Research iPSYCH Denmark Center for Integrative Sequencing Aarhus University Aarhus Denmark Department of Human Genetics David Geffen School of Medicine University of California Los Angeles Los Angeles CA USA Human Brain Collection Core National Institute of Mental Health Bethesda MD USA Laboratory of Neurogenomic Biomarkers Centre for Integrative Biology (CIBIO) University of Trento Trento Italy Clare Hall University of Cambridge Cambridge UK University of North Carolina at Chapel Hill Chapel Hill NC USA Karolinska Institutet Stockholm Sweden Department of Psychiatry University of Pittsburgh Pittsburgh PA USA Systems Biology Sage Bionetworks Seattle WA USA Section of Genetic Medicine Department of Medicine University of Chicago Chicago IL USA Integrated Technology Research Laboratories Pharmaceutical Research Division Takeda Pharmaceutical Company Limited Fujisawa Japan Neuropsychiatry Section Department of Psychiatry Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Neuropsychiatric Signaling Program Department of Psychiatry Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Psychiatry JJ Peters Virginia Medical Center Bronx NY USA Department of Neuroscience Icahn School of Medicine at Mount Sinai New York New York NY USA Friedman Brain Institute

Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex genome-wide association study (GWAS) loci and may disentangle the role of different tissues in disease development. We used the largest eQTL reference panel for the dorso-lateral prefrontal cortex (DLPFC) to create a set of gene expression predictors and demonstrate their utility. We applied DLPFC and 12 GTEx-brain predictors to 40,299 schizophrenia cases and 65,264 matched controls for a large transcriptomic imputation study of schizophrenia. We identified 413 genic associations across 13 brain regions. Stepwise conditioning identified 67 non-MHC genes, of which 14 did not fall within previous GWAS loci. We identified 36 significantly enriched pathways, including hexosaminidase-A deficiency, and multiple porphyric disorder pathways. We investigated developmental expression patterns among the 67 non-MHC genes and identified specific groups of pre- and postnatal expression.

关键词： Gene expression Genome-wide association studies Schizophrenia Transcriptomics

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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

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Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the BRATS challenge

arXiv

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arXiv 2018年

作者： Bakas, Spyridon Reyes, Mauricio Jakab, Andras Bauer, Stefan Rempfler, Markus Crimi, Alessandro Shinohara, Russell Takeshi Berger, Christoph Ha, Sung Min Rozycki, Martin Prastawa, Marcel Alberts, Esther Lipkova, Jana Freymann, John Kirby, Justin Bilello, Michel Fathallah-Shaykh, Hassan M. Wiest, Roland Kirschke, Jan Wiestler, Benedikt Colen, Rivka Kotrotsou, Aikaterini Lamontagne, Pamela Marcus, Daniel Milchenko, Mikhail Nazeri, Arash Weber, Marc-Andr Mahajan, Abhishek Baid, Ujjwal Gerstner, Elizabeth Kwon, Dongjin Acharya, Gagan Agarwal, Manu Alam, Mahbubul Albiol, Alberto Albiol, Antonio Albiol, Francisco J. Alex, Varghese Allinson, Nigel Amorim, Pedro H.A. Amrutkar, Abhijit Anand, Ganesh Andermatt, Simon Arbel, Tal Arbelaez, Pablo Avery, Aaron Azmat, Muneeza Pranjal, B. Bai, Wenjia Banerjee, Subhashis Barth, Bill Batchelder, Thomas Batmanghelich, Kayhan Battistella, Enzo Beers, Andrew Belyaev, Mikhail Bendszus, Martin Benson, Eze Bernal, Jose Bharath, Halandur Nagaraja Biros, George Bisdas, Sotirios Brown, James Cabezas, Mariano Cao, Shilei Cardoso, Jorge M. Carver, Eric N. Casamitjana, Adri Castillo, Laura Silvana Cat, Marcel Cattin, Philippe Cérigues, Albert Chagas, Vinicius S. Chandra, Siddhartha Chang, Yi-Ju Chang, Shiyu Chang, Ken Chazalon, Joseph Chen, Shengcong Chen, Wei Chen, Jefferson W. Chen, Zhaolin Cheng, Kun Choudhury, Ahana Roy Chylla, Roger Clrigues, Albert Colleman, Steven Colmeiro, Ramiro German Rodriguez Combalia, Marc Costa, Anthony Cui, Xiaomeng Dai, Zhenzhen Dai, Lutao Daza, Laura Alexandra Deutsch, Eric Ding, Changxing Dong, Chao Dong, Shidu Dudzik, Wojciech Eaton-Rosen, Zach Egan, Gary Escudero, Guilherme Estienne, Tho Everson, Richard Fabrizio, Jonathan Fan, Yong Fang, Longwei Feng, Xue Ferrante, Enzo Fidon, Lucas Fischer, Martin French, Andrew P. Fridman, Naomi Fu, Huan Fuentes, David Gao, Yaozong Gates, Evan Gering, David Gholami, Amir Gierke, Willi Glocker, Ben Gong, Mingming Gonzlez-Vill, Sandra Grosges, T. Guan, Yuanfang Guo, Sheng Gupta, Sudeep Han, Woo-Sup Han, Il Song Harmuth, Ko Center for Biomedical Image Computing and Analytics University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Institute for Surgical Technology and Biomechanics University of Bern Bern Switzerland Center for MR-Research University Children's Hospital Zurich Zurich Switzerland Support Centre for Advanced Neuroimaging Inselspital Institute for Diagnostic and Interventional Neuroradiology Bern University Hospital Bern Switzerland University Hospital of Zurich Zurich Switzerland Center for Clinical Epidemiology and Biostatistics University of Pennsylvania Philadelphia United States Image-Based Biomedical Modeling Group Technical University of Munich Munich Germany Icahn School of Medicine Mount Sinai Health System New YorkNY United States Leidos Biomedical Research Inc. Frederick National Laboratory for Cancer Research FrederickMD21701 United States Cancer Imaging Program National Cancer Institute National Institutes of Health BethesdaMD20814 United States Department of Neurology University of Alabama at Birmingham BirminghamAL United States Department of Diagnostic Radiology University of Texas MD Anderson Cancer Center HoustonTX United States Department of Psychology Washington University St. LouisMO United States Neuroimaging Informatics and Analysis Center Washington University St. LouisMO United States Department of Radiology Washington University St. LouisMO United States Institute of Diagnostic and Interventional Radiology Pediatric Radiology and Neuroradiology University Medical Center Rostock Ernst-Heydemann-Str. 6 Rostock18057 Germany Tata Memorial Centre Homi Bhabha National Institute Mumbai India Shri Guru Gobind Singhji Institute of Engineering and Technology Nanded India NVIDIA Santa Clara

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and non-enhancing core. This intrinsic heterogeneity is also portrayed in their radio-phenotype, as their sub-regions are depicted by varying intensity profiles disseminated across multi-parametric magnetic resonance imaging (mpMRI) scans, reflecting varying biological properties. Their heterogeneous shape, extent, and location are some of the factors that make these tumors difficult to resect, and in some cases inoperable. The amount of resected tumor is a factor also considered in longitudinal scans, when evaluating the apparent tumor for potential diagnosis of progression. Furthermore, there is mounting evidence that accurate segmentation of the various tumor sub-regions can offer the basis for quantitative image analysis towards prediction of patient overall survival. This study assesses the state-of-the-art machine learning (ML) methods used for brain tumor image analysis in mpMRI scans, during the last seven instances of the International Brain Tumor Segmentation (BraTS) challenge, i.e., 2012-2018. Specifically, we focus on i) evaluating segmentations of the various glioma sub-regions in pre-operative mpMRI scans, ii) assessing potential tumor progression by virtue of longitudinal growth of tumor sub-regions, beyond use of the RECIST/RANO criteria, and iii) predicting the overall survival from pre-operative mpMRI scans of patients that underwent gross total resection. Finally, we investigate the challenge of identifying the best ML algorithms for each of these tasks, considering that apart from being diverse on each instance of the challenge, the multi-institutional mpMRI BraTS dataset has also been a continuously evolving/growing dataset. Copyright © 2018, The Authors. All rights reserved.

关键词： Tumors

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The medical segmentation decathlon

arXiv

引用

arXiv 2021年

作者： Antonelli, Michela Reinke, Annika Bakas, Spyridon Farahani, Keyvan Kopp-Schneider, Annette Landman, Bennett A. Litjens, Geert Menze, Bjoern Ronneberger, Olaf Summers, Ronald M. van Ginneken, Bram Bilello, Michel Bilic, Patrick Christ, Patrick F. Do, Richard K.G. Gollub, Marc J. Heckers, Stephan H. Huisman, Henkjan Jarnagin, William R. McHugo, Maureen K. Napel, Sandy Golia Pernicka, Jennifer S. Rhode, Kawal Tobon-Gomez, Catalina Vorontsov, Eugene Hulsmon, Hankan Meakin, James A. Ourselin, Sebastien Wiesenfarth, Manuel Arbeláez, Pablo Bae, Byeonguk Chen, Sihong Daza, Laura Feng, Jianjiang He, Baochun Isensee, Fabian Ji, Yuanfeng Jia, Fucang Kim, Namkug Kim, Ildoo Merhof, Dorit Pai, Akshay Park, Beomhee Perslev, Mathias Rezaiifar, Ramin Rippel, Oliver Sarasua, Ignacio Shen, Wei Son, Jaemin Wachinger, Christian Wang, Liansheng Wang, Yan Xia, Yingda Xu, Daguang Xu, Zhanwei Zheng, Yefeng Simpson, Amber L. Maier-Hein, Lena Cardoso, M. Jorge School of Biomedical Engineering & Imaging Sciences King’s College London London United Kingdom Heidelberg Germany Heidelberg Germany Faculty of Mathematics and Computer Science University of Heidelberg Heidelberg Germany University of Pennsylvania PhiladelphiaPA United States BethesdaMD United States Heidelberg Germany Electrical Engineering and Computer Science Vanderbilt University NashvilleTN United States Radboud University Medical Center Radboud Institute for Health Sciences Nijmegen Netherlands Quantitative Biomedicine University of Zurich Zurich Switzerland DeepMind London United Kingdom School of Computing Department of Biomedical and Molecular Sciences Queen’s University KingstonON Canada Department of Surgery Memorial Sloan Kettering Cancer Center New YorkNY United States BethesdaMD United States Department of Informatics Technische Universität München Germany Department of Radiology Memorial Sloan Kettering Cancer Center New YorkNY United States Department of Psychiatry & Behavioral Sciences Vanderbilt University Medical Center NashvilleTN United States Department of Radiology Stanford University StanfordCA United States Department of Computer Science and Software Engineering École Polytechnique de Montréal Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Medical Faculty University of Heidelberg Heidelberg Germany VUNO Inc. Seoul Korea Republic of Universidad de los Andes Colombia Department of Automation Tsinghua University Beijing China Heidelberg Germany Department of Computer Science Xiamen University Xiamen361005 China Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China Kakao Brain Korea Republic of Institute of Imaging & Computer Vision RWTH Aachen University Aachen Germany Cere

International challenges have become the de facto standard for comparative assessment of image analysis algorithms given a specific task. Segmentation is so far the most widely investigated medical image processing task, but the various segmentation challenges have typically been organized in isolation, such that algorithm development was driven by the need to tackle a single specific clinical problem. We hypothesized that a method capable of performing well on multiple tasks will generalize well to a previously unseen task and potentially outperform a custom-designed solution. To investigate the hypothesis, we organized the Medical Segmentation Decathlon (MSD)—a biomedical image analysis challenge, in which algorithms compete in a multitude of both tasks and modalities. The underlying data set was designed to explore the axis of difficulties typically encountered when dealing with medical images, such as small data sets, unbalanced labels, multi-site data and small objects. The MSD challenge confirmed that algorithms with a consistent good performance on a set of tasks preserved their good average performance on a different set of previously unseen tasks. Moreover, by monitoring the MSD winner for two years, we found that this algorithm continued generalizing well to a wide range of other clinical problems, further confirming our hypothesis. Three main conclusions can be drawn from this study: (1) state-of-the-art image segmentation algorithms are mature, accurate, and generalize well when retrained on unseen tasks;(2) consistent algorithmic performance across multiple tasks is a strong surrogate of algorithmic generalizability;(3) the training of accurate AI segmentation models is now commoditized to non AI *** Codes 68T07. © 2021, CC BY-NC-SA.

关键词： Image segmentation

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