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arXiv 2017年

作者： Roth, Kilian Nossek, Josef A. Next Generation and Standards Intel Deutschland GmbH Neubiberg85579 Germany Department of Electrical and Computer Engineering Technical University Munich Munich80290 Germany Department of Teleinformatics Engineering Federal University of Ceara Fortaleza Brazil

For future millimeter Wave (mmWave) mobile communication systems, the use of analog/hybrid beamforming is envisioned to be an important aspect. The synthesis of beams is a key technology to enable the best possible operation during beam search, data transmission and MultiUser MIMO (MU MIMO) operation. The method for synthesizing beams developed in this work is based on previous work in radar technology considering only phase array antennas. With this technique, it is possible to generate a desired beam of any shape with the constraints of the desired target transceiver antenna frontend. It is not constraint to a certain antenna array geometry, and can handle 1D, 2D and even 3D antenna array geometries, e.g. cylindrical arrays. The numerical examples show that the method can synthesize beams by considering a user defined trade-off between gain, transition width and passband ripples. Copyright © 2017, The Authors. All rights reserved.

关键词： Millimeter waves

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A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3 (vol 111, pg 96, 2024)

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AMERICAN JOURNAL OF HUMAN GENETICS 2024年第4期11卷 805-805页

作者： Paul, Maimuna S. Michener, Sydney L. Pan, Hongling Chan, Hiuling Pfliger, Jessica M. Rosenfeld, Jill A. Lerma, Vanesa C. Tran, Alyssa Longley, Megan A. Lewis, Richard A. Weisz-Hubshman, Monika Bekheirnia, Mir Reza Bekheirnia, Nasim Massingham, Lauren Zech, Michael Wagner, Matias Engels, Hartmut Cremer, Kirsten Mangold, Elisabeth Peters, Sophia Trautmann, Jessica Perne, Claudia Mester, Jessica L. Sacoto, Maria J. Guillen Person, Richard McDonnell, Pamela P. Cohen, Stacey R. Lusk, Laina Cohen, Ana S. A. Le Pichon, Jean-Baptiste Pastinen, Tomi Zhou, Dihong Engleman, Kendra Racine, Caroline Faivre, Laurence Moutton, Sebastien Denomme-Pichon, Anne-Sophie Koh, Hyun Yong Poduri, Annapurna Bolton, Jeffrey Knopp, Cordula Suh, Dong Sun Julia Maier, Andrea Toosi, Mehran Beiraghi Karimiani, Ehsan Ghayoor Maroofian, Reza Schaefer, Gerald Bradley Ramakumaran, Vijayalakshmi Vasudevan, Pradeep Banos-Pinero, Benito Pagnamenta, Alistair T. Prasad, Chitra Osmond, Matthew Schuhmann, Sarah Vasileiou, Georgia Russ-Hall, Sophie Scheffer, Ingrid E. Carvill, Gemma L. Mefford, Heather Bacino, Carlos A. Lee, Brendan H. Chao, Hsiao-Tuan Department of Pediatrics Section of Neurology and Developmental Neuroscience Baylor College of Medicine Houston TX USA Jan and Dan Duncan Neurological Research Institute Texas Children’s Hospital Houston TX USA Cain Pediatric Neurology Research Foundation Laboratories Jan and Dan Duncan Neurological Research Institute Houston TX USA Department of Molecular and Human Genetics Baylor College of Medicine Houston TX USA Augustana College Rock Island IL USA Summer Undergraduate Research Training (SMART) Program Baylor College of Medicine Houston TX USA Graduate Program in Electrical and Computer Engineering Rice University Houston TX USA Department of Psychology University of Houston Houston TX USA Department of Ophthalmology Baylor College of Medicine Houston TX USA Renal Genetics Clinic Baylor College of Medicine Houston TX USA Rhode Island Hospital and Hasbro Children’s Hospital Providence RI USA Institute of Neurogenomics Helmholtz Zentrum München Munich Germany Institute of Human Genetics School of Medicine Technical University Munich Germany Institute for Advanced Study Technical University of Munich Garching Germany Division of Pediatric Neurology Developmental Neurology and Social Pediatrics Dr. von Hauner Children’s Hospital Munich Germany Institute of Human Genetics School of Medicine University Hospital Bonn University of Bonn Bonn Germany GeneDx Gaithersburg MD USA Epilepsy NeuroGenetics Initiative (ENGIN) Division of Neurology Children’s Hospital of Philadelphia Philadelphia PA USA Department of Neurology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Children’s Mercy Kansas City Genomic Medicine Center The University of Missouri-Kansas City (UMKC) School of Medicine Kansas City MO USA Department of Pediatrics Children’s Mercy Kansas City Kansas City MO USA Children’s Mercy Research Institute Kansas City MO USA Children’s Mercy Hospital Kansas City MO USA University Hospital Dijon Franc

PPFIA3 encodes the protein-tyrosine phosphatase, receptor-type, F-polypeptide-interacting-protein-alpha-3 (PPFIA3), which is a member of the LAR-protein-tyrosine phosphatase-interacting-protein (liprin) family involved in synapse formation and function, synaptic vesicle transport, and presynaptic active zone assembly. The protein structure and function are evolutionarily well conserved, but human diseases related to PPFIA3 dysfunction are not yet reported in OMIM. Here, we report 20 individuals with rare PPFIA3 variants (19 heterozygous and 1 compound heterozygous) presenting with developmental delay, intellectual disability, hypotonia, dysmorphisms, microcephaly or macrocephaly, autistic features, and epilepsy with reduced penetrance. Seventeen unique PPFIA3 variants were detected in 18 families. To determine the pathogenicity of PPFIA3 variants in vivo, we generated transgenic fruit flies producing either human wild-type (WT) PPFIA3 or five missense variants using GAL4-UAS targeted gene expression systems. In the fly overexpression assays, we found that the PPFIA3 variants in the region encoding the N-terminal coiled-coil domain exhibited stronger phenotypes compared to those affecting the C-terminal region. In the loss-of-function fly assay, we show that the homozygous loss of fly Liprin-α leads to embryonic lethality. This lethality is partially rescued by the expression of human PPFIA3 WT, suggesting human PPFIA3 function is partially conserved in the fly. However, two of the tested variants failed to rescue the lethality at the larval stage and one variant failed to rescue lethality at the adult stage. Altogether, the human and fruit fly data reveal that the rare PPFIA3 variants are dominant-negative loss-of-function alleles that perturb multiple developmental processes and synapse formation.

关键词： neurodevelopmental disorder synaptic protein active zone protein Mendelian phenotypes fruit flies

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Online Edge Caching in Fog-Aided Wireless Networks

arXiv

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arXiv 2017年

作者： Azimi, Seyyed Mohammadreza Simeone, Osvaldo Sengupta, Avik Tandon, Ravi CWiP Department of Electrical and Computer Engineering New Jersey Institute of Technology NewarkNJ United States Next Generation and Standards iCDG Intel Corporation Santa Clara United States University of Arizona TucsonAZ United States

In a Fog Radio Access Network (F-RAN) architecture, edge nodes (ENs), such as base stations, are equipped with limited-capacity caches, as well as with fronthaul links that can support given transmission rates from a cloud processor. Existing information-theoretic analyses of content delivery in F-RANs have focused on offline caching with separate content placement and delivery phases. In contrast, this work considers an online caching set-up, in which the set of popular files is time-varying and both cache replenishment and content delivery can take place in each time slot. The analysis is centered on the characterization of the long-term Normalized Delivery Time (NDT), which captures the temporal dependence of the coding latencies accrued across multiple time slots in the high signal-to-noise ratio regime. Online caching and delivery schemes based on reactive and proactive caching are investigated, and their performance is compared to optimal offline caching schemes both analytically and via numerical results. Copyright © 2017, The Authors. All rights reserved.

关键词： Radio access networks

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General Capacity Region for the Fully Connected Three-Node Packet Erasure Network

General Capacity Region for the Fully Connected Three-Node P...

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作者： Han, Jaemin Wang, Chih-Chun Next Generation and Standards in Intel HillsboroOR97124 United States School of Electrical and Computer Engineering Purdue University West LafayetteIN47907 United States

This paper studies the capacity region when three nodes 1,2,3 communicate with each other by sending packets through unreliable wireless medium. For each time slot, with some probabilities a packet sent by node i may be received by both of the other nodes j and k;received only by node j (or node k);or received by neither node. Interference is avoided by enforcing that at most one node can transmit in each time slot. We assume that node i can always reach node j, possibly with the help of the third node k, for any i ne j pairs (thus the term fully connected). One notable example of this model is any CSMA-based Wi-Fi network with three nodes within the hearing range of each other. © 2016 IEEE.

关键词： Network coding

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Concurrent surface electromyography and force myography classification during times of prosthetic socket shift and user fatigue

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Journal of rehabilitation and assistive technologies engineering 2017年 4卷 2055668317708731-2055668317708731页

作者： Joe Sanford Rita Patterson Dan O Popa Next Gen Systems Group Department of Electrical Engineering University of Texas-Arlington Arlington TX USA. Department of Family and Osteopathic Manipulative Medicine University of North Texas-Health Science Center Fort Worth TX USA. Department of Electrical and Computer Engineering University of Louisville Louisville KY USA.

OBJECTIVE:Surface electromyography has been a long-standing source of signals for control of powered prosthetic devices. By contrast, force myography is a more recent alternative to surface electromyography that has the potential to enhance reliability and avoid operational challenges of surface electromyography during use. In this paper, we report on experiments conducted to assess improvements in classification of surface electromyography signals through the addition of collocated force myography consisting of piezo-resistive sensors. METHODS:Force sensors detect intrasocket pressure changes upon muscle activation due to changes in muscle volume during activities of daily living. A heterogeneous sensor configuration with four surface electromyography-force myography pairs was investigated as a control input for a powered upper limb prosthetic. Training of two different multilevel neural perceptron networks was employed during classification and trained on data gathered during experiments simulating socket shift and muscle fatigue. RESULTS:Results indicate that intrasocket pressure data used in conjunction with surface EMG data can improve classification of human intent and control of a powered prosthetic device compared to traditional, surface electromyography only systems. SIGNIFICANCE:Additional sensors lead to significantly better signal classification during times of user fatigue, poor socket fit, as well as radial and ulnar wrist deviation. Results from experimentally obtained training data sets are presented.

关键词： Hand biomechanics human machine interface physical human–robot interaction pressure sensitive robot skin prosthetic device

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Fault diagnosis for multi-energy flows of energy internet: Framework and prospects

Fault diagnosis for multi-energy flows of energy internet: F...

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2017 IEEE Conference on Energy Internet and Energy System Integration, EI2 2017

作者： Wang, Tao Wang, Jun Fan, Zhennan Wei, Xiaoguang Zang, Tianlei Pérez-Jiménez, Mario J. Huang, Tao School of Electrical Engineering and Electronic Information Sichuan Province Key Laboratory of Power Electronics Energy-saving Technologies and Equipment Key Laboratory of Fluid and Power Machinery Ministry of Education Xihua University Chengdu China School of Electrical Engineering Southwest Jiaotong University Chengdu China State Key Laboratory of Security Control and Simulation of Power Systems and Large Scale Generation Department of Electrical Engineering Tsinghua University Beijing China Research Groupon Natural Computing Department of Computer Science and Artificial Intelligence University of Sevilla Sevilla Spain Department of Energy Politecnico di Torino Torino Italy

ISBN: (纸本)9781538614273

Energy Internet (EI) is an inevitable development trend of energy systems under the background of technology development, environmental pressure and energy transition. Multi-energy flow coupling is one of the key characteristics of the EI, which enhances the interoperability of different types of energy flows while consequently increases the probability of cascading failures. Therefore it is of great significance to study the multi-energy flow fault diagnosis of the EI to ensure its safe and stable operation as well as the continuous energy supply. This paper introduces the concept of multi-energy flow cascading fault of the EI for the first time. The energy internet framework for multi-energy flow cascading fault diagnosis is firstly proposed, and then characteristics of various energy networks in the EI are analyzed from the perspective of fault diagnosis. Finally, future research prospects are discussed. © 2017 IEEE.

关键词： Failure analysis

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Modeling and analysis of secondary controlled virtual synchronous generator with dynamic droop for microgrid

Modeling and analysis of secondary controlled virtual synchr...

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IEEE Conference on Energy Internet and Energy System Integration (EI2)

作者： Weihang Yan David Wenzhong Gao Fang Zhang Lin Cheng Shijie Yan Department of Electrical and Computer Engineering University of Denver Denver USA State Key Laboratory of Control and Simulation of Power Systems and Generation Equipment Tsinghua University Beijing China College of Information Science and Technology Northeastern University Shenyang China

ISBN: (纸本)9781538614280

In this paper, a dynamic droop mechanism is proposed to damp the synchronizing oscillation that exists in a virtual synchronous generator based distributed generator system without varying the steady-state active-power-loop droop coefficient. In order to eliminate the steady-state error introduced due to load changes or generator trips, a distributed secondary controller based on extremum seeking is employed so that microgrid frequency can be restored to nominal value. Besides, the small-signal model of virtual synchronous generator system is presented under d-q reference frame where virtual synchronous generator is deployed as a PV node. Moreover, the linearized system model of virtual synchronous generator with dynamic droop mechanism is derived and its advantage is discussed. Finally, a modified IEEE 14 bus microgrid system is established in Matlab/Simulink platform. Simulation results demonstrate the validity and feasibility of the proposed method.

关键词： Mathematical model Microgrids Synchronous generators Frequency control Inverters Power system stability Power system dynamics

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Walking control based on step timing adaptation

arXiv

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arXiv 2017年

作者： Khadiv, Majid Herzogr, Alexander Righetti, Ludovic Righetti, Ludovic Movement Generation and Control Group Max-Planck Institute for Intelligent Systems Germany Google X Department of Mechanical Engineering K. N. Toosi University of Technology Tehran Iran Department of Electrical and Computer Engineering Department of Mechanical and Aerospace Engineering New York University United States

Step adjustment for biped robots has been shown to improve gait robustness, however the adaptation of step timing is often neglected in control strategies because it gives rise to non-convex problems when optimized over several steps. In this paper, we argue that it is not necessary to optimize walking over several steps to guarantee stability and that it is sufficient to merely select the next step timing and location. From this insight, we propose a novel walking pattern generator with linear constraints that optimally selects step location and timing at every control cycle. The resulting controller is computationally simple, yet guarantees that any viable state will remain viable in the future. We propose a swing foot adaptation strategy and show how the approach can be used with an inverse dynamics controller without any explicit control of the center of mass or the foot center of pressure. This is particularly useful for biped robots with limited control authority on their foot center of pressure, such as robots with point feet and robots with passive ankles. Extensive simulations on a humanoid robot with passive ankles subject to external pushes and foot slippage demonstrate the capabilities of the approach in cases where the foot center of pressure cannot be controlled and emphasize the importance of step timing adaptation to stabilize walking. Copyright © 2017, The Authors. All rights reserved.

关键词： Timing circuits

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Estimation and measurement of closed-loop delays in the actual WACS of Guizhou Power Grid

Estimation and measurement of closed-loop delays in the actu...

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2016 IEEE Power and Energy Society General Meeting, PESGM 2016

作者： Zhang, Fang Cheng, Lin Li, Xiong Min, Zeng Sun, Yuanzhang Chow, Joe H. State Key Laboratory of Control and Simulation of Power Systems and Generation Equipment Tsinghua University Beijing China School of Electrical Engineering Wuhan University China Department of Electrical Computer and Systems Engineering Rensselaer Polytechnic Institute TroyNY12180 United States

ISBN: (纸本)9781509041688

The characterization of the closed-loop delays in a wide-area control system (WACS) is an important foundation for further research. The method to estimate and measure the closed-loop delay in actual WACSs were proposed in this paper. Then, the closed-loop delays in the actual WACS in Guizhou Power Grid in China were measured and analyzed. Also, the measured delays were used to verify the normal distribution estimation model proposed in previous research. The results indicate that the closed-loop delay in the WACS followed a normal distribution. © 2016 IEEE.

关键词： Normal distribution

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Online edge caching and wireless delivery in fog-aided networks with dynamic content popularity

arXiv

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arXiv 2017年

作者： Azimi, Seyyed Mohammadreza Simeone, Osvaldo Sengupta, Avik Tandon, Ravi CWiP Department of Electrical and Computer Engineering New Jersey Institute of Technology NewarkNJ United States Centre for Telecommunications Research Department of Informatics King's College London United Kingdom Next Generation and Standards iCDG Intel Corporation Santa Clara United States University of Arizona TucsonAZ United States

Fog Radio Access Network \(F-RAN\) architectures can leverage both cloud processing and edge caching for content delivery to the users. To this end, F-RAN utilizes caches at the edge nodes \(ENs\) and fronthaul links connecting a cloud processor to ENs. Assuming time-invariant content popularity, existing information-theoretic analyses of content delivery in F-RANs rely on offline caching with separate content placement and delivery phases. In contrast, this work focuses on the scenario in which the set of popular content is time-varying, hence necessitating the online replenishment of the ENs' caches along with the delivery of the requested files. The analysis is centered on the characterization of the long-term Normalized Delivery Time \(NDT\), which captures the temporal dependence of the coding latencies accrued across multiple time slots in the high signal-to-noise ratio regime. Online edge caching and delivery schemes are investigated for both serial and pipelined transmission modes across fronthaul and edge segments. Analytical results demonstrate that, in the presence of a time-varying content popularity, the rate of fronthaul links sets a fundamental limit to the long-term NDT of FRAN system. Analytical results are further verified by numerical simulation, yielding important design insights. Copyright © 2017, The Authors. All rights reserved.

关键词： Radio access networks

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