检索结果-内蒙古大学图书馆

Reduced myelin contributes to cognitive impairment in patients with monogenic small vessel disease

Alzheimer's and Dementia 2025年第5期21卷 e70127页

作者： Denecke, Jannis Dewenter, Anna Lee, Jongho Franzmeier, Nicolai Valentim, Carolina Kopczak, Anna Dichgans, Martin Pirpamer, Lukas Gesierich, Benno Duering, Marco Ewers, Michael Institute for Stroke and Dementia Research (ISD) LMU University Hospital Munich Germany Laboratory for Imaging Science and Technology Department of Electrical and Computer Engineering Seoul South Korea Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy University of Gothenburg Gothenburg Sweden Munich Cluster for Systems Neurology (SyNergy) Munich Germany German Center for Neurodegenerative Disease (DZNE) Munich Germany Medical Image Analysis Center (MIAC) and Department of Biomedical Engineering University of Basel Basel Switzerland

INTRODUCTION: Myelin is pivotal for signal transfer and thus cognition. Cerebral small vessel disease (cSVD) is primarily associated with white matter (WM) lesions and diffusion changes;however, myelin alterations and related cognitive impairments in cSVD remain unclear. METHODS: We included 64 patients with familial cSVD (i.e., cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy [CADASIL]) and 20 cognitively unimpaired individuals. χ separation applied to susceptibility weighted imaging was used to assess myelin and iron within WM hyperintensities, normal appearing WM, and two strategic fiber tracts. Diffusion-based mean diffusivity and free water were analyzed for comparisons. Cognitive impairment was assessed by the Trail Making Test. RESULTS: CADASIL patients showed reduced myelin within WM hyperintensities and its penumbra in the normal appearing WM. Myelin was moderately correlated with diffusion and iron changes and associated with slower processing speed controlled for diffusion and iron alterations. DISCUSSION: Myelin constitutes WM alterations distinct from diffusion changes and substantially contributes to explaining cognitive impairment in cSVD. Highlights: χ-negative magnetic resonance signal was reduced within white matter hyperintensities and normal appearing white matter in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, suggesting widespread myelin decreases due to cerebral small vessel disease (cSVD). χ-negative values were only moderately associated with diffusion tensor imaging derived indices including free water and mean diffusivity, suggesting that χ separation depicts distinct microstructural changes in cSVD. Alterations in χ-negative values made a unique contribution to explain processing speed impairment, even when controlled for diffusion and iron changes. © 2025 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf

关键词： cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy chi separation diffusion magnetic resonance imaging susceptibility mapping white matter hyperintensities

来源：评论

学校读者我要写书评

暂无评论

Preface to the Special Issue on Flexible Materials and Structures for Bioengineering,Sensing,and Energy Applications

引用

Journal of Semiconductors 2020年第4期41卷 1-2页

作者： Yongfeng Mei Wei Gao Hui Fang Yuan Lin Guozhen Shen Department of Materials Science State Key Laboratory of ASIC and SystemsFudan UniversityShanghai200433China Department of Medical Engineering Division of Engineering and Applied ScienceCalifornia Institute of TechnologyPasadenaCAUSA Department of Electrical and Computer Engineering Northeastern UniversityBostonMA 02115USA State Key Laboratory of Electronic Thin films and Integrated Devices University of Electronic Science and Technology of ChinaChengdu610054China State Key Laboratory for Superlattices and Microstructures Institute of SemiconductorsChinese Academy of SciencesBeijing100083China

Human body with curved and soft interfaces requests advanced flexible materials and structures for the interaction with organs and signal collection from targets in applications such as bioengineering and diagnostic *** them,it is highly demanded to achieve creative design in flexible materials and structures with great stretchable capability for required *** this end,both inorganic and organic materials could be adopted and designed with assembly and self-assembly methods for flexible electronics and *** or flexible materials and structures inspired by nature can lead to highly conformal contacts between devices and the human *** approaches hold great potential for applications in flexible electronics,medical imaging technology and portable disease *** strategy on related sensors/actuator and energy storage/generation devices could overcome certain limitations on flexible materials engineering and thus advance the field as *** these methods would deliver a profound impact to our future intelligent society.

关键词： overcome curved engineering

来源：评论

学校读者我要写书评

暂无评论

Cramér-rao bound optimization for joint radar-communication design

arXiv

引用

arXiv 2021年

作者： Liu, Fan Liu, Ya-Feng Li, Ang Masouros, Christos Eldar, Yonina C. The Department of Electrical and Electronic Engineering Southern University of Science and Technology Shenzhen518055 China The State Key Laboratory of Scientific and Engineering Computing Institute of Computational Mathematicsand Scientific/Engineering Computing Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing100190 China The School of Information and Communications Engineering Faculty of Electronic and Information Engineering Xi’an Jiaotong University Xi’anShaanxi710049 China The Department of Electronic and Electrical Engineering University College London LondonWC1E 7JE United Kingdom The Faculty of Mathematics and Computer Science Weizmann Institute of Science Rehovot Israel

In this paper, we propose multi-input multi-output (MIMO) beamforming designs towards joint radar sensing and multi-user communications. We employ the Cramér-Rao bound (CRB) as a performance metric of target estimation, under both point and extended target scenarios. We then propose minimizing the CRB of radar sensing while guaranteeing a pre-defined level of signal-to-interference-plus-noise ratio (SINR) for each communication user. For the single-user scenario, we derive a closed form for the optimal solution for both cases of point and extended targets. For the multi-user scenario, we show that both problems can be relaxed into semidefinite programming by using the semidefinite relaxation approach, and prove that the global optimum can always be obtained. Finally, we demonstrate numerically that the globally optimal solutions are reachable via the proposed methods, which provide significant gains in target estimation performance over state-of-the-art benchmarks. Copyright © 2021, The Authors. All rights reserved.

关键词： Signal to noise ratio

来源：评论

学校读者我要写书评

暂无评论

Orthogonally polarized RF optical single sideband generation with integrated ring resonators

引用

Journal of Semiconductors 2021年第4期42卷 53-66页

作者： Mengxi Tan Xingyuan Xu Jiayang Wu Thach G.Nguyen Sai T.Chu Brent E.Little Arnan Mitchell Roberto Morandotti David J.Moss Optical Sciences Centre Swinburne University of TechnologyHawthornVIC 3122Australia Electro-Photonics Laboratory Department of Electrical and Computer Systems EngineeringMonash UniversityVIC3800Australia School of Engineering RMIT UniversityMelbourneVIC 3001Australia Department of Physics City University of Hong KongHong KongChina State Key Laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision MechanicsChinese Academy of ScienceXi'an 710119China INRS-Énergie Matériaux et Télécommunications1650 Boulevard Lionel-BouletVarennesQuébecJ3X 1S2Canada Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China

We review recent work on narrowband orthogonally polarized optical RF single sideband generators as well as dualchannel equalization,both based on high-Q integrated ring *** devices operate in the optical telecommunications C-band and enable RF operation over a range of either fixed or thermally tuneable *** operate via TE/TM mode birefringence in the *** achieve a very large dynamic tuning range of over 55 dB for both the optical carrier-to-sideband ratio and the dual-channel RF equalization for both the fixed and tunable devices.

关键词： microwave photonics micro-ring resonators radio frequency

来源：评论

学校读者我要写书评

暂无评论

Current reversal and particle separation in Brownian transport

引用

Physical Review Research 2021年第3期3卷 033162-033162页

作者： Hai-Wei Hu Lin Du Liang-Hui Qu Zi-Lu Cao Zi-Chen Deng Ying-Cheng Lai School of Mathematics and Statistics Northwestern Polytechnical University Xi'an 710072 China MIIT Key Laboratory of Dynamics and Control of Complex Systems Northwestern Polytechnical University Xi'an 710072 China School of Aeronautics Northwestern Polytechnical University Xi'an 710072 China School of Electrical Computer and Energy Engineering Arizona State University Tempe Arizona 85287 USA Department of Physics Arizona State University Tempe Arizona 85287 USA

In transport of micro- or nanosized particles through a confined structure driven by thermal fluctuations and external forcing—a situation that arises commonly in a variety of fields in physical and biological sciences, efficient and controllable separation of particles of different sizes is an important but challenging problem. We study, numerically and analytically, the diffusion dynamics of Brownian particles through the biologically relevant setting of a spatially periodic structure, subject to static and temporally periodic forcing. Molecular dynamical simulations reveal that the mean velocity in general depends sensitively on the particle size. The phenomenon of current reversal is uncovered, where particles larger than or smaller than a critical size diffuse in exactly opposite directions. This striking behavior occurs in a wide range of the forcing amplitude and provides a mechanism to separate the Brownian particles of different sizes. Besides the forcing amplitude, other parametric quantities characterizing the forcing profile, such as the temporal asymmetry, can also be exploited to modulate or control the transport dynamics of particles of different sizes. To gain a theoretical understanding, we exploit the Fick-Jacobs approximation to obtain a one-dimensional description of the diffusion problem, which enables key quantities characterizing the diffusion process, such as the mean velocity, to be predicted. In the regime of weak forcing, a reasonable agreement between theory and numerical results is achieved. Beyond the weakly forcing regime, the diffusion approximation breaks down, causing the theoretical predictions to deviate from the numerical results, into which we provide physical insights. Our findings have potential applications in optimizing transport in microfluidic devices or through biological channels.

关键词： Brownian motion Classical transport Brownian dynamics Langevin equation Stochastic differential equations

来源：评论

学校读者我要写书评

暂无评论

Secret-Key Distillation across a Quantum Wiretap Channel under Restricted Eavesdropping

引用

Physical Review Applied 2020年第2期14卷 024044-024044页

作者： Ziwen Pan Kaushik P. Seshadreesan William Clark Mark R. Adcock Ivan B. Djordjevic Jeffrey H. Shapiro Saikat Guha Department of Electrical & Computer Engineering College of Engineering University of Arizona Tucson Arizona 85719 USA College of Optical Sciences University of Arizona Tucson Arizona 85719 USA General Dynamics Mission Systems Scottsdale Arizona 85257 USA Research Laboratory of Electronics Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA

The theory of quantum cryptography aims to guarantee unconditional information-theoretic security against an omnipotent eavesdropper. In many practical scenarios, however, the assumption of an all-powerful adversary is excessive and can be relaxed considerably. In this paper we study secret-key distillation across a lossy and noisy quantum wiretap channel between Alice and Bob, with a separately parameterized realistically lossy quantum channel to the eavesdropper Eve. We show that under such restricted eavesdropping, the key rates achievable can exceed the secret-key-distillation capacity against an unrestricted eavesdropper in the quantum wiretap channel. Furthermore, we show upper bounds on the key rates based on the relative entropy of entanglement. This simple restricted eavesdropping model is widely applicable, for example, to free-space quantum optical communication, where realistic collection of light by Eve is limited by the finite size of her optical aperture. Future work will include calculating bounds on the amount of light Eve can collect under various realistic scenarios.

关键词： Quantum channels Quantum communication Quantum cryptography

来源：评论

学校读者我要写书评

暂无评论

Lightweight Task-Oriented Semantic Communication Empowered by Large-Scale AI Models

引用

IEEE Transactions on Vehicular Technology 2025年

作者： Liu, Chuanhong Guo, Caili Yang, Yang Chen, Mingzhe Quek, Tony Q. S. Beijing University of Posts and Telecommunications Beijing Key Laboratory of Network System Architecture and Convergence School of Information and Communication Engineering Beijing100876 China Beijing University of Posts and Telecommunications Beijing Laboratory of Advanced Information Networks School of Information and Communication Engineering Beijing100876 China University of Miami Department of Electrical and Computer Engineering Institute for Data Science and Computing Coral GablesFL United States Singapore University of Technology and Design Dept. of Information Systems Technology and Design 487372 Singapore

Recent studies have focused on leveraging large-scale artificial intelligence (LAI) models to improve semantic representation and compression capabilities. However, the substantial computational demands of LAI models pose significant challenges for real-time communication scenarios. To address this, this paper proposes utilizing knowledge distillation (KD) techniques to extract and condense knowledge from LAI models, effectively reducing model complexity and computation latency. Nevertheless, the inherent complexity of LAI models leads to prolonged inference times during distillation, while their lack of channel awareness compromises the distillation performance. These limitations make standard KD methods unsuitable for task-oriented semantic communication scenarios. To address these issues, we propose a fast distillation method featuring a pre-stored compression mechanism that eliminates the need for repetitive inference, significantly improving efficiency. Furthermore, a channel adaptive module is incorporated to dynamically adjust the transmitted semantic information based on varying channel conditions, enhancing communication reliability and adaptability. In addition, an information bottleneck-based loss function is derived to guide the fast distillation process. Simulation results verify that the proposed scheme outperform baselines in term of task accuracy, model size, computation latency, and training data requirements. © 1967-2012 IEEE.

关键词： NP-hard

来源：评论

学校读者我要写书评

暂无评论

Photonic radio frequency channelizers based on Kerr optical micro-combs

引用

Journal of Semiconductors 2021年第4期42卷 17-32页

作者： Mengxi Tan Xingyuan Xu Jiayang Wu Thach G.Nguyen Sai T.Chu Brent E.Little Roberto Morandotti Arnan Mitchell David J.Moss Optical Sciences Centre Swinburne University of TechnologyHawthornVIC 3122Australia Electro-Photonics Laboratory Department of Electrical and Computer Systems EngineeringMonash UniversityVIC3800Australia School of Engineering RMIT UniversityMelbourneVIC 3001Australia Department of Physics City University of Hong KongHong KongChina State Key Laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision MechanicsChinese Academy of ScienceXi'an 710119China INRS-Énergie Matériaux et Télécommunications1650 Boulevard Lionel-BouletVarennesQuébecJ3X 1S2Canada Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China

We review recent work on broadband RF channelizers based on integrated optical frequency Kerr micro-combs combined with passive micro-ring resonator filters,with microcombs having channel spacings of 200 and 49 *** approach to realizing RF channelizers offers reduced complexity,size,and potential cost for a wide range of applications to microwave signal detection.

关键词： microwave photonic signal channelization integrated optical frequency comb

来源：评论

学校读者我要写书评

暂无评论

Passive Quadrupedal Gait Synchronization for Extra Robotic Legs Using a Dynamically Coupled Double Rimless Wheel Model

Passive Quadrupedal Gait Synchronization for Extra Robotic L...

引用

IEEE International Conference on Robotics and Automation (ICRA)

作者： Daniel J. Gonzalez H. Harry Asada Robotics Research Center in the Department of Electrical Engineering and Computer Science United States Military Academy West Point NY USA d’Arbeloff Laboratory for Information Systems and Technology in the Department of Mechanical Engineering Massachusetts Institute of Technology Cambridge MA USA

ISBN: (数字)9781728173955

ISBN: (纸本)9781728173962

The Extra Robotic Legs (XRL) system is a robotic augmentation worn by a human operator consisting of two articulated robot legs that walk with the operator and help bear a heavy backpack payload. It is desirable for the Human-XRL quadruped system to walk with the rear legs lead the front by 25% of the gait period, minimizing the energy lost from foot impacts while maximizing balance stability. Unlike quadrupedal robots, the XRL cannot command the human's limbs to coordinate quadrupedal locomotion. Using a pair of Rimless Wheel models, it is shown that the systems coupled with a spring and damper converge to the desired 25% phase difference. A Poincaré return map was generated using numerical simulation to examine the convergence properties to different coupler design parameters, and initial conditions. The Dynamically Coupled Double Rimless Wheel system was physically realized with a spring and dashpot chosen from the theoretical results, and initial experiments indicate that the desired synchronization properties may be achieved within several steps using this set of passive components alone.

关键词： Legged locomotion Wheels Synchronization Couplers Robot kinematics

来源：评论

学校读者我要写书评

暂无评论

Blockchain Technology Based Decentralized Energy Trading for Multiple-Microgrid systems 3

Blockchain Technology Based Decentralized Energy Trading for...

引用

3rd IEEE Conference on Energy Internet and Energy System Integration, EI2 2019

作者： Li, Ting Zhang, Wei Chen, Ning Qian, Minhui Xu, Ying School of Electrical Engineering and Automation Harbin Institute of Technology Harbin China State Key Laboratory of Operation and Control of Renewable Energy Storage Systems China EPRI Nanjing China University of Central Florida Department of Electrical Engineering Computer Science Orlando United States

ISBN: (纸本)9781728131375

With the emerging technology for distributed generation and urge of improving quality of service of power supply for energy users, more and more Microgrids (MGs) are integrated into the distributed networks to serve the energy users. These Microgrids are gradually formulating a Multi-Microgrid System (MMGS, Multi-Microgrid System), which will play an important role for the future energy supply. Building a centralized control center not only increases the expense of investment, but also brings the issues of maintaining fairness among energy users. To address these problems, this paper proposes a peer-to-peer method for energy trading of MMGS, based on the idea of decentralized trading. An auction-based trading mechanism suitable for peer-to-peer energy trading is proposed first. For this mechanism, the MGs firstly declare their energy buying bids or selling quotations. Then, the market-clearing price is determined by using a unified weight clearing algorithm in a decentralized manner. By applying the edge technology of Blockchain, the implementation of the proposed peer-to-peer energy trading method, including the architecture, procedures, security check, etc., is also discussed. The proposed Blockchain-based energy trading platform can realize the decentralized and autonomous energy trading of MGs within an MMGS. A case study with an MMGS with 10 MG units is provided to demonstrate the effectiveness of the proposed approach. © 2019 IEEE.

关键词： Blockchain

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：