In this work, a thorough assessment of the robustness of complementary channel HfO2 ferroelectric FET (FeFET) against total ionizing dose (TID) radiation is conducted, with the goal of determining its suitability for ...
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The reconstruction of electrical current densities from magnetic field measurements is an important technique with applications in materials science, circuit design, quality control, plasma physics, and biology. Analy...
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The reconstruction of electrical current densities from magnetic field measurements is an important technique with applications in materials science, circuit design, quality control, plasma physics, and biology. Analytic reconstruction methods exist for planar currents, but break down in the presence of high-spatial-frequency noise or large standoff distance, restricting the types of systems that can be studied. Here, we demonstrate the use of a deep convolutional neural network for current density reconstruction from two-dimensional images of vector magnetic fields acquired by a quantum diamond microscope . Trained network performance significantly exceeds analytic reconstruction for data with high noise or large standoff distances. This machine learning technique can perform quality inversions on lower-signal-to-noise-ratio data, significantly reducing the data collection time and permitting reconstructions of weaker and three-dimensional current sources.
Magic is a property of quantum states that enables universal fault-tolerant quantum computing using simple sets of gate operations. Understanding the mechanisms by which magic is created or destroyed is, therefore, a ...
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We demonstrate quantum logic enhanced sensitivity for a macroscopic ensemble of solid-state, hybrid two-qubit sensors. We achieve over a factor of 30 improvement in the single-shot signal-to-noise ratio, translating t...
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We demonstrate quantum logic enhanced sensitivity for a macroscopic ensemble of solid-state, hybrid two-qubit sensors. We achieve over a factor of 30 improvement in the single-shot signal-to-noise ratio, translating to an ac magnetic field sensitivity enhancement exceeding an order of magnitude for time-averaged measurements. Using the electronic spins of nitrogen vacancy (NV) centers in diamond as sensors, we leverage the on-site nitrogen nuclear spins of the NV centers as memory qubits, in combination with homogeneous and stable bias and control fields, ensuring that all of the ∼109 two-qubit sensors are sufficiently identical to permit global control of the NV ensemble spin states. We find quantum logic sensitivity enhancement for multiple measurement protocols with varying optimal sensing intervals, including XY8 and DROID-60 dynamical decoupling, as well as correlation spectroscopy, using an applied ac magnetic field signal. The results are independent of the nature of the target signal and broadly applicable to measurements using NV centers and other solid-state spin ensembles. This work provides a benchmark for macroscopic ensembles of quantum sensors that employ quantum logic or quantum error correction algorithms for enhanced sensitivity.
This work presents a 3D-printed,modular,electrochemical sensor-integrated transwell system for monitoring cellular and molecular events in situ without sample extraction or microfluidics-assisted downstream *** additi...
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This work presents a 3D-printed,modular,electrochemical sensor-integrated transwell system for monitoring cellular and molecular events in situ without sample extraction or microfluidics-assisted downstream *** additive manufacturing techniques such as 3D printing,shadow masking,and molding are used to fabricate this modular system,which is autoclavable,biocompatible,and designed to operate following standard operating protocols(SOPs)of cellular *** to the platform is a flexible porous membrane,which is used as a cell culture substrate similarly to a commercial transwell *** electrochemical sensors fabricated on the membrane allow direct access to cells and their products.A pair of gold electrodes on the top side of the membrane measures impedance over the course of cell attachment and growth,characterized by an exponential decrease(~160%at 10Hz)due to an increase in the double layer capacitance from secreted extracellular matrix(ECM)*** voltammetry(CV)sensor electrodes,fabricated on the bottom side of the membrane,enable sensing of molecular release at the site of cell culture without the need for downstream ***-time detection of ferrocene dimethanol injection across the membrane showed a three order-of-magnitude higher signal at the membrane than in the bulk media after reaching *** modular sensor-integrated transwell system allows unprecedented direct,real-time,and noninvasive access to physical and biochemical information,which cannot be obtained in a conventional transwell system.
Gut–brain axis(GBA)communication relies on serotonin(5-HT)signaling between the gut epithelium and the peripheral nervous system,where 5-HT release patterns from the basolateral(i.e.,bottom)side of the epithelium act...
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Gut–brain axis(GBA)communication relies on serotonin(5-HT)signaling between the gut epithelium and the peripheral nervous system,where 5-HT release patterns from the basolateral(i.e.,bottom)side of the epithelium activate nerve *** have been few quantitative studies of this gut-neuron signaling due to a lack of real-time measurement tools that can access the basolateral gut *** vitro platforms allow quantitative studies of cultured gut tissue,but they mainly employ offline and endpoint assays that cannot resolve dynamic molecular-release ***,we present the modification of a microporous cell culture membrane with carbon nanotube-coated gold(Au-CNT)electrodes capable of continuous,label-free,and direct detection of 5-HT at physiological *** characterization of single-walled carbon nanotube(SWCNT)-coated Au electrodes shows increased electroactive surface area,5-HT specificity,sensitivity,and saturation time,which are correlated with the CNT film drop-cast *** microliters of CNT films,with a 10-min saturation time,0.6μA/μM 5-HT sensitivity,and reliable detection within a linear range of 500 nM–10μM 5-HT,can be targeted for high-concentration,high-time-resolution 5-HT *** films(12.5μL)with a 2-h saturation time,4.5μA/μM 5-HT sensitivity,and quantitative detection in the linear range of 100 nM–1μM can target low concentrations with low time *** electrodes achieved continuous detection of dynamic diffusion across the porous membrane,mimicking basolateral 5-HT release from cells,and detection of cell-released 5-HT from separately cultured RIN14B cell ***-integrated cell culture systems such as this can improve in vitro molecular detection mechanisms and aid in quantitative GBA signaling studies.
The efficient single-photon-emission capabilities of quantum dot molecules position them as promising platforms for quantum information processing. Furthermore, quantum dot molecules feature a “decoherence-free” sub...
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The efficient single-photon-emission capabilities of quantum dot molecules position them as promising platforms for quantum information processing. Furthermore, quantum dot molecules feature a “decoherence-free” subspace that enables spin qubits with long coherence times. To efficiently read out the spin state within this subspace requires the optical cycling of isolated transitions that originate from a triplet manifold within the quantum dot molecule. We propose and theoretically study a two-stage spin-readout protocol within this decoherence-free subspace that allows single-shot readout performance. The process incorporates a microwave π pulse and optical cycling of the isolated transitions, which induces fluorescence that allows us to identify the initial spin state. This protocol offers enhanced readout fidelity compared to previous schemes that rely on the excitation of transitions that strongly decay to multiple ground states or require long initialization via slow optically forbidden transitions. By simulating the performance of the protocol, we show that an optimal spin-readout fidelity of over 97% and single-shot readout performance are achievable for a photon-collection efficiency of just 0.12%. This high readout performance for such realistic photon-collection conditions within the decoherence-free subspace expands the potential of quantum dot molecules as building blocks for quantum networks.
Interest in cryo-Electron Microscopy (EM) imaging has skyrocketed in recent years due to its pristine views of macromolecules and materials. As advances in instrumentation and computing algorithms spurred this progres...
Going beyond the limited design freedoms of traditional photonic crystals, we experimentally show how photonic metacrystals exploit the inclusion of subwavelength dielectric scatterers in the unit cell to deterministi...
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ISBN:
(数字)9781957171050
ISBN:
(纸本)9781665466660
Going beyond the limited design freedoms of traditional photonic crystals, we experimentally show how photonic metacrystals exploit the inclusion of subwavelength dielectric scatterers in the unit cell to deterministically modify k-space and real space profiles.
Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitati...
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Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitations of conventional rigid counterparts. Despite rapid advancement in bench-side research over the last decade, the market adoption of flexible sensors remains limited. To ease and to expedite their deployment, here, we identify bottlenecks hindering the maturation of flexible sensors and propose promising solutions. We first analyze continued...challenges in achieving satisfactory sensing performance for real-world applications and then summarize issues in compatible sensor-biology interfaces, followed by brief discussions on powering and connecting sensor networks. Issues en route to commercialization and for sustainable growth of the sector are also analyzed, highlighting environmental concerns and emphasizing nontechnical issues such as business, regulatory, and ethical considerations. Additionally, we look at future intelligent flexible sensors. In proposing a comprehensive roadmap, we hope to steer research efforts towards common goals and to guide coordinated development strategies from disparate communities. Through such collaborative
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