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arXiv 2021年

作者： Lu, Xiangri Ma, Hongbin Zhang, Jingcheng State Key Laboratory of Intelligent Decision and Control for Complex Systems Beijing Institute ofTechnology Beijing China Institute of Pattern Recognition and Intelligent Systems School of Automation Beijing Institute ofTechnology China Institute of Navigation Guidance and Control School of Automation Beijing Institute of

Recent work has shown that the activation function of the convolutional neural network can meet the Lipschitz condition, then the corresponding convolutional neural network structure can be constructed according to the scale of the data set, and the data set can be trained more deeply, more accurately and more effectively. In this article, we have accepted the experimental results and introduced the core block N − Gauss, N − Gauss, and Swish (Conv1, Conv2, FC1) neural network structure design to train MNIST, CIFAR10, and CIFAR100 respectively. Experiments show that N − Gauss gives full play to the main role of nonlinear modeling of activation functions, so that deep convolutional neural networks have hierarchical nonlinear mapping learning capabilities. At the same time, the training ability of N − Gauss on simple one-dimensional channel small data sets is equivalent to the performance of ReLU and Swish. Copyright © 2021, The Authors. All rights reserved.

关键词： Gaussian distribution

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NiuEM: A Nested-iterative Unsupervised Learning Model for Single-particle Cryo-EM Image Processing

NiuEM: A Nested-iterative Unsupervised Learning Model for Si...

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2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020

作者： Hu, Rui Cai, Jiaming Zheng, Wangjie Yang, Yang Shen, Hong-Bin Shanghai Jiao Tong University Key Lab. of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering Department of Computer Science and Engineering Shanghai200240 China Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University Key Laboratory of System Control and Information Processing Ministry of Education of China Shanghai200240 China Shanghai Jiao Tong University Department of Bioinformatics and Biostatistics Shanghai200240 China

ISBN: (纸本)9781728162157

Cryo-electron microscopy (cryo-EM) has become a mainstream technology for solving spatial structures of biomacromolecules, while the processing of cryo-EM images is a very challenging task. One of the great challenges is the high noise in the images. A common method is to cluster the images with close projecting angles to get mean images, which are used for 3D reconstruction. However, due to the extremely low signal-to-noise-ratio, common clustering methods often fail to obtain high-quality mean images, leading to poorly reconstructed structures. In this study, we present a new unsupervised learning framework, called NiuEM, to discriminate images captured from different angles and yield cluster-mean images. NiuEM first generates pseudo-labels and then exploits both contrastive loss and cross-entropy loss for training convolutional layers to learn feature representations. Moreover, the pseudo-labels are updated iteratively to enhance the reliability of labels. We assess the performance of NiuEM on four data sets via both visualized and quantitative experiments. Especially, two kinds of metrics are adopted to measure the performance, regarding the clustering quality and the resolution of reconstructed 3D models, respectively. The experimental results show that NiuEM achieves very competitive clustering accuracy in the comparison with the state-of-the-art image clustering methods. Moreover, the cluster mean images yielded by NiuEM lead to better initial 3D models compared with the mainstream reconstruction tools. © 2020 IEEE.

关键词： Image reconstruction

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NiuEM: A Nested-iterative Unsupervised Learning Model for Single-particle Cryo-EM Image Processing

NiuEM: A Nested-iterative Unsupervised Learning Model for Si...

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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Rui Hu Jiaming Cai Wangjie Zheng Yang Yang Hong-Bin Shen Shanghai Jiao Tong University and Key Laboratory of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering Shanghai China Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University and Key Laboratory of System Control and Information Processing Ministry of Education of China Shanghai China Shanghai Jiao Tong University Shanghai China

ISBN: (数字)9781728162157

ISBN: (纸本)9781728162164

关键词： Three-dimensional displays Feature extraction Image reconstruction Task analysis Solid modeling Electron microscopy Convolutional neural networks

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EEG-Based Brain-Computer Interfaces Are Vulnerable to Backdoor Attacks

Research Square

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Research Square 2021年

作者： Meng, Lubin Huang, Jian Zeng, Zhigang Jiang, Xue Yu, Shan Jung, Tzyy-Ping Lin, Chin-Teng Chavarriaga, Ricardo Wu, Dongrui Ministry of Education Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan China Brainnetome Center and National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences Beijing China La Jolla CA United States Center for Advanced Neurological Engineering Institute of Engineering in Medicine UCSD La Jolla CA United States Centre of Artificial Intelligence Faculty of Engineering and Information Technology University of Technology Sydney Australia ZHAW DataLab Zürich University of Applied Sciences Winterthur8401 Switzerland

Research and development of electroencephalogram (EEG) based brain-computer interfaces (BCIs) have advanced rapidly, partly due to the wide adoption of sophisticated machine learning approaches for decoding the EEG signals. However, recent studies have shown that machine learning algorithms are vulnerable to adversarial attacks, e.g., the attacker can add tiny adversarial perturbations to a test sample to fool the model, or poison the training data to insert a secret backdoor. Previous research has shown that adversarial attacks are also possible for EEG-based BCIs. However, only adversarial perturbations have been considered, and the approaches are theoretically sound but very difficult to implement in practice. This article proposes to use narrow period pulse for poisoning attack of EEG-based BCIs, which is more feasible in practice and has never been considered before. One can create dangerous backdoors in the machine learning model by injecting poisoning samples into the training set. Test samples with the backdoor key will then be classified into the target class specified by the attacker. What most distinguishes our approach from previous ones is that the backdoor key does not need to be synchronized with the EEG trials, making it very easy to implement. The effectiveness and robustness of the backdoor attack approach is demonstrated, highlighting a critical security concern for EEG-based BCIs. © 2021, CC BY.

关键词： Electroencephalography

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Mem Brain: An Easy-to-Use Online Webserver for Transmembrane Protein Structure Prediction

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Nano-Micro Letters 2018年第1期10卷 12-19页

作者： Xi Yin Jing Yang Feng Xiao Yang Yang Hong-Bin Shen Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University Key Laboratory of System Control and Information Processing Ministry of Education of China Department of Computer Science Shanghai Jiao Tong University Key Laboratory of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering

Membrane proteins are an important kind of proteins embedded in the membranes of cells and play crucial roles in living organisms, such as ion channels,transporters, receptors. Because it is difficult to determinate the membrane protein's structure by wet-lab experiments,accurate and fast amino acid sequence-based computational methods are highly desired. In this paper, we report an online prediction tool called Mem Brain, whose input is the amino acid sequence. Mem Brain consists of specialized modules for predicting transmembrane helices, residue–residue contacts and relative accessible surface area of a-helical membrane proteins. Mem Brain achieves aprediction accuracy of 97.9% of ATMH, 87.1% of AP,3.2 ± 3.0 of N-score, 3.1 ± 2.8 of C-score. Mem BrainContact obtains 62%/64.1% prediction accuracy on training and independent dataset on top L/5 contact prediction,respectively. And Mem Brain-Rasa achieves Pearson correlation coefficient of 0.733 and its mean absolute error of13.593. These prediction results provide valuable hints for revealing the structure and function of membrane *** Brain web server is free for academic use and available at ***/bioinf/Mem Brain/.

关键词： Transmembrane a-helices Structure prediction Machine learning Contact map prediction Relative accessible surface area

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Automatic Monitoring of Driver's Physiological Parameters Based on Microarray Camera

Automatic Monitoring of Driver's Physiological Parameters Ba...

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IEEE Eurasia Conference on Biomedical Engineering, Healthcare and Sustainability (ECBIOS)

作者： Jiancheng Zou Zhengzheng Li Peizhou Yan Institute of Image Processing and Pattern Recognition North China University of Technology Beijing Key Laboratory of Urban Rod Traffic Intelligent Control Technology North China University of Technology Shijingshan District Beijing China

Driver's physical and mental states are very important factors affecting the driving states. Traffic accidents are occurred by accompanying abnormal physiological parameters. So how to monitor automatically driver's physiological parameters is an important problem. A real-time driver's physiological parameters monitoring method based on microarray camera is proposed in this paper. Firstly, we use a microarray camera to acquire videos in real time without contact. Secondly, the videos are registered and fused into a high quality video. Thirdly, deep learning framework is used to capture driver's facial data quickly. Then based on the principle of imaging photoplethysmography (IPPG) algorithm, physiological parameters such as heart rate (HR) and oxygen saturation (SpO 2 ) are monitored in real time. Results of expression analysis can further support the physiological parameters monitoring results. The experimental results show that the method proposed in this paper can monitor the physiological parameters of drivers in real time and accurately, and it is hopeful to play an active role in improving traffic safety.

关键词： Biomedical monitoring Monitoring Cameras Videos Heart rate Real-time systems

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EEG-Based Brain-Computer Interfaces Are Vulnerable to Backdoor Attacks

arXiv

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arXiv 2020年

作者： Meng, Lubin Huang, Jian Zeng, Zhigang Jiang, Xue Yu, Shan Jung, Tzyy-Ping Lin, Chin-Teng Chavarriaga, Ricardo Wu, Dongrui Ministry of Education Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan China Brainnetome Center National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences Beijing China La Jolla CA United States Center for Advanced Neurological Engineering Institute of Engineering in Medicine Ucsd La Jolla CA United States Centre of Artificial Intelligence Faculty of Engineering and Information Technology University of Technology Sydney Australia Zhaw DataLab Zürich University of Applied Sciences Winterthur8401 Switzerland

Research and development of electroencephalogram (EEG) based brain-computer interfaces (BCIs) have advanced rapidly, partly due to deeper understanding of the brain and wide adoption of sophisticated machine learning approaches for decoding the EEG signals. However, recent studies have shown that machine learning algorithms are vulnerable to adversarial attacks. This article proposes to use narrow period pulse for poisoning attack of EEG-based BCIs, which is implementable in practice and has never been considered before. One can create dangerous backdoors in the machine learning model by injecting poisoning samples into the training set. Test samples with the backdoor key will then be classified into the target class specified by the attacker. What most distinguishes our approach from previous ones is that the backdoor key does not need to be synchronized with the EEG trials, making it very easy to implement. The effectiveness and robustness of the backdoor attack approach is demonstrated, highlighting a critical security concern for EEG-based BCIs and calling for urgent attention to address it. Copyright © 2020, The Authors. All rights reserved.

关键词： Electroencephalography

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J-Measure Based Pruning for Advancing Classification Performance of Information Entropy Based Rule Generation

J-Measure Based Pruning for Advancing Classification Perform...

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International Conference on Machine Learning and Cybernetics (ICMLC)

作者： Han Liu Mihaela Cocea Weili Ding School of Computer Science and Informatics Cardiff University Queen’s Buildings 5 The Parade Cardiff United Kingdom School of computing University of Portsmouth Buckingham Building Lion Terrace Portsmouth United Kingdom Laboratory of Pattern Recognition and Intelligent Systems Key Laboratory of Industrial Computer Control Engineering of Heibei Provience Yanshan University Qinghuangdao China

ISBN: (纸本)9781538652152

Learning of classification rules is a popular approach of machine learning, which can be achieved through two strategies, namely divide-and-conquer and separate-and-conquer. The former is aimed at generating rules in the form of a decision tree, whereas the latter generates if-then rules directly from training data. From this point of view, the above two strategies are referred to as decision tree learning and rule learning, respectively. Both learning strategies can lead to production of complex rule based classifiers that overfit training data, which has motivated researchers to develop pruning algorithms towards reduction of overfitting. In this paper, we propose a J-measure based pruning algorithm, which is referred to as Jmean-pruning. The proposed pruning algorithm is used to advance the performance of the information entropy based rule generation method that follows the separate and conquer strategy. An experimental study is reported to show how Jmean-pruning can effectively help the above rule learning method avoid overfitting. The results show that the use of Jmean-pruning achieves to advance the performance of the rule learning method and the improved performance is very comparable or even considerably better than the one of C4.5.

关键词： Decision trees Learning systems Training data Entropy Information entropy Machine learning Machine learning algorithms

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Constructing multi-modality and multi-classifier radiomics predictive models through reliable classifier fusion

arXiv

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arXiv 2017年

作者： Zhou, Zhiguo Zhou, Zhi-Jie Hao, Hongxia Li, Shulong Chen, Xi Zhang, You Folkert, Michael Wang, Jing Department of Radiation Oncology UT Southwestern Medical Center DallasTX United States High-Tech Institute of Xi'an Xi'an China Department of Information and Control Engineering Xi'an University of Technology Xi'an China School of Computer Science and Technology Key Laboratory of Intelligent Perception and Image Understanding of Ministry of Education Xidian University Xi'an China School of Biomedical Engineering Southern Medical Unversity Guangzhou China Institute of Image Processing and Pattern Recognition Xi'an Jiaotong Unversity Xi'an China

Radiomics aims to extract and analyze large numbers of quantitative features from medical images and is highly promising in staging, diagnosing, and predicting outcomes of cancer treatments. Nevertheless, several challenges need to be addressed to construct an optimal radiomics predictive model. First, the predictive performance of the model may be reduced when features extracted from an individual imaging modality (e.g. PET, CT, MRI) are blindly combined into a single predictive model. Second, because many different types of classifiers are available to construct a predictive model, selecting an "optimal" classifier for a particular application is still challenging. In this work, we developed multi-modality and multi-classifier radiomics predictive models that address the aforementioned issues in currently available models. Specifically, a new reliable classifier fusion strategy was proposed to optimally combine output from different modalities and classifiers. In this strategy, modality-specific classifiers were first trained, and an analytic evidential reasoning (ER) rule was developed to fuse the output score from each modality to construct an optimal predictive model. One public datasets and two clinical case studies were performed to validate model performance. The experimental results indicated that the proposed ER rule based radiomics models outperformed the traditional models that rely on a single classifier or simply use combined features from different modalities. Copyright © 2017, The Authors. All rights reserved.

关键词： Diagnosis

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Corrigendum to “Road detection algorithm for Autonomous Navigation Systems based on dark channel prior and vanishing point in complex road scenes” [Robot. Auton. Syst. 85 (2016) 1–11]

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Robotics and Autonomous Systems 2017年 88卷 202-202页

作者： Yong Li Weili Ding Xuguang Zhang Zhaojie Ju Laboratory of Pattern Recognition and Intelligent Systems Key Laboratory of Industrial Computer Control Engineering of Hebei Province Department of Automation Institute of Electrical Engineering Yanshan University Qinghuangdao Hebei 066004 China College of Information Science and Engineering Northeastern University Shenyang Liaoning 110004 China School of Computing University of Portsmouth PO1 3HE UK

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