检索结果-内蒙古大学图书馆

High-Performance Nitrogen Selectivity through Selective Nitrate Reduction on Nickel-Supported Copper Foam Architectures

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Process Safety and Environmental Protection 2025年

作者： Thi Nhat-Tuyen Nguyen Kiruthika Mariappan Jih-Hsing Chang Tsin-Hai Wang Subramanian Sakthinathan Chao-Lin Liu Ching-Lung Chen International Ph.D. Program in Innovative Technology of Biomedical Engineering and Medical Devices Ming Chi University of Technology New Taipei City 243303 Taiwan Department of Safety Health and Environmental Engineering Ming Chi University of Technology New Taipei City 243303 Taiwan Department of Environmental Engineering and Management Chaoyang University of Technology Taichung 413310 Taiwan Department of Chemical Engineering and Materials Science Yuan Ze University Zhongli 32003 Taiwan Department of Materials and Mineral Resources Engineering National Taipei University of Technology No.1 Section 3 Chung-Hsiao East Road Taipei 106 Taiwan Department of Chemical Engineering Ming Chi University of Technology New Taipei City 243303 Taiwan R&D Center of Biochemical Engineering Technology Ming Chi University of Technology New Taipei City 243303 Taiwan Center for Environmental Sustainability and Human Health Ming Chi University of Technology New Taipei City 243303 Taiwan Center for Sustainability and Energy Technologies Chang Gung University Taoyuan 33302 Taiwan

In this study, Nickel@Copper (Ni@Cu) bimetallic electrodes were fabricated via electrodeposition to assess their efficacy in electrochemical nitrate reduction (ENR). The Ni@Cu 3m electrodes achieved a remarkable nitrate (NO 3 − ) reduction efficiency of 96.09% and nitrogen selectivity of 96.08% at a current density of 1.36 mA/cm² over an 8-hour reaction period. Extensive characterization techniques, including TEM, XPS, and XRd, were employed to analyze the structural and morph.logical features of the electrodes. Cyclic voltammetry was used to examine electron transfer interactions between surface nitrogen (N 2 ) species and copper foam electrodes, nitrate (NO 3 − ) reduction commenced within a potential range of −0.8 V to 0.1 V. The Ni loading on copper foam was optimized to enhance catalytic performance, and the effect of different ph.levels on activity was systematically studied. The Ni@Cu 3m electrodes demonstrated excellent long-term stability over 10 cycles, maintaining high efficiency and selectivity over multiple cycles. These results highlight the strong potential of bimetallic electrodes as efficient and reliable candidates for NO 3 − reduction in wastewater treatment applications.

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CCL5 Protects Cortical Neuron Function by Regulating M2 Microglia Activation After Mild Traumatic Brain Injury

SSRN

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SSRN 2022年

作者： Tsai, Yih-Jeng Ho, Man-Hau Yen, Chia-Hung Wang, Jia-Yi Burnouf, Thierry Chen, Chia-Yen Wang, Yun Chiang, Yung-Hsiao Hoffer, Barry J. Chou, Szu-Yi Department of Otolaryngology Head and Neck Surgery Shin Kong Wu HoSu Memorial Hospital Taipei Taiwan School of Medicine Fu Jen Catholic University New Taipei City Taiwan Ph.D. Program in Medical Neuroscience College of Medical Science and Technology Taipei Medical University National Health Research Institute Taiwan Graduate Institute of Neural Regenerative Medicine College of Medical Science and Technology Taipei Medical University Taipei Taiwan Department of Biological Science and Technology National Pingtung University of Science and Technology Neipu Pingtung91201 Taiwan Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei11031 Taiwan Department of Neurosurgery Taipei Medical University Hospital Taipei11031 Taiwan Neuroscience Research Center Taipei Medical University Taipei11031 Taiwan International PhD Program in Biomedical Engineering College of Biomedical Engineering Taipei Medical University Taipei Taiwan Graduate Institute of Biomedical Materials and Tissue Engineering College of Biomedical Engineering Taipei Medical University Taipei Taiwan NeuroTMULille International Laboratory Taipei Medical University Taipei Taiwan International PhD Program in Cell Therapy and Regeneration Medicine College of Medicine Taipei Medical University Taipei Taiwan Brain and Consciousness Research Centre TMU Shuang Ho Hospital New Taipei City Taiwan Center for Neuropsychiatric Research National Health Research Institutes Zhunan Miaoli County Taiwan Department of Surgery School of Medicine College of Medicine Taipei Medical University 11031 Taiwan Department of Neurosurgery Case Western Reserve University School of Medicine ClevelandOH United States Scientist Emeritus National Institutes of Health United States International Master Program in Medical Neuroscience College of Medical Science and Technology Taipei Medical University Taipei Taiwan

Cytokines and chemokines play important roles in inflammation and repair following brain injury. M1 microglia are pro-inflammatory which produce cytokines and lead to neural injury;in contrast, M2 microglia are anti-inflammatory, release neurotroph.c factors, and promote neural repair processes. Chemokine CCL5, increased after TBI, shows a neuroprotective function by reducing oxidative stress. CCL5 may contribute to the balance between oxidative stress and immune responses after brain injury. Herein, we investigated the role of CCL5 in microglial polarization after mild traumatic brain injury, focusing on the cerebral cortex.C57BL/6 and CCL5 knockout (CCL5-KO) mice were given a mild traumatic brain injury (TBI) using weight-drop. Neurological parameters such as motor and sensory functions were analyzed by mNSS score, accelerating rotarod, beam walking, and adhesive removal tests. Oxidative stress and neuron damage were measured by NAdph.oxidase activity, hypoxyloprobe staining and FJC. Performance of motor and sensory functions in both WT and CCL5-KO mice were impaired after brain injury which recovered after 7 days-post-injury (dpi) in the WT group but only after 14 days in the CCL5-KO mouse group. RT-qPCR analysis revealed that pro-inflammation cytokines - IL-1β, TNF-α, and IL-6 were higher in CCL5-KO mice compared to WT mice at 4 and 14 dpi. In contrast, M2-like microglia markers - IL-10 and Agr-1 were increased in WT mouse cortical tissue at 4 dpi. Oxidative stress increased both M1 and M2- related cytokine expression in BV2 cells treated with H 2 O 2;CCL5 treatment increased M2- but suppressed M1- related cytokine gene activation. Intranasal delivery of CCL5 reduced neuronal oxidative stress, increased IL-10 expression and improved motor and sensory functions in CCL5-KO mice after brain *** summary, CCL5, which alters immune responses and protects neurons from TBI damage, has an important function in regulating M2-like microglial polarization during post-

关键词： Polarization

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Spatiotemporal variation and clustered routes of atmosph.ric speciated mercury transported from the East and West Channels of Taiwan Island to South China Sea

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Atmosph.ric Research 2025年 325卷

作者： Mei-Yun Xiao Wen-Hsi Cheng Yu-Lun Tseng Po-Hsuan Yen Chung-Shin Yuan Jia-Yi Zhao Ming-Shiou Jeng Institute of Environmental Engineering National Sun Yat-sen University Taiwan ROC Ph.D. Program in Maritime Science and Technology College of Maritime National Kaohsiung University of Science and Technology Kaohsiung City Taiwan ROC Net Zero Emissions and Resource Recycling Technology Research Center National Sun Yat-Sen University Kaohsiung Taiwan ROC Biodiversity Research Center Academia Sinica Nangang Taipei City Taiwan ROC Green Island Marine Research Station Biodiversity Research Center Academia Sinica Green Island Taitung County Taiwan ROC

This study investigated the spatiotemporal variation and long-range transport characteristics of atmosph.ric speciated mercury (ASM) along the West and East Channels surrounding Taiwan Island toward the South China Sea (SCS) in East Asia. Field sampling was conducted at three remote island sites, and potential sources of ASM were examined using backward trajectory clustering and regional fire maps. Seasonally, ASM concentrations followed the order: spring > winter > fall > summer, with higher ASM levels observed in the western waters of Taiwan Island than those in the eastern waters. Among the mercury species, gaseous elemental mercury (GEM) was predominant, and followed by particulate-bound mercury (PBM) and gaseous oxidized mercury (GOM), with total gaseous mercury (TGM = GEM+GOM) accounting for 92.1–98.4 % of ASM. Clustered trajectory analysis indicated that Asian Northeastern Monsoons (ANMs) may transport ASMs originating from continental sources in North and East Asia to the island sites via long-range transport. Slash-and-burn activities in the Indochina Peninsula and mainland China during spring and winter contributed to elevated ASM levels. The West Channel exhibited a pronounced “channel effect,” amplifying industrial emissions across the Taiwan Strait and resulting in higher ASM levels at the Penghu Islands. Conversely, the East Channel received diluted air masses through long-range transport from the Korean Peninsula and North China via Green Island and the Bashi Channel, leading to relatively lower ASM levels at the dongsha Island. Overall, this study highlights the importance of seasonal circulation patterns and regional combustion sources in shaping mercury distribution in the marine boundary layer of East Asia.

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Agar-altered foaming bacterial cellulose with carvacrol for active food packaging applications

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Food Packaging and Shelf Life 2024年 42卷

作者： Kusuma, Anita Chandra Chou, Yu-Chieh Hsieh, Chen-Che Santoso, Shella Permatasari Go, Alchris Woo Lin, Hong-Ting Victor Hsiao, I.-Lun Lin, Shin-Ping Master Program in Food Safety Taipei Medical University 250 Wu-Hsing Street Taipei 11031 Taiwan Ph.D. Program in Drug Discovery and Development Industry Taipei Medical University 250 Wu-Hsing Street Taipei 11031 Taiwan Institute of Biotechnology National Taiwan University 1 Roosevelt Rd. Section 4 Taipei 10617 Taiwan Department of Chemical Engineering Widya Mandala Surabaya Catholic University Kalijudan 37 Surabaya 60114 Indonesia Department of Chemical Engineering National Taiwan University of Science and Technology 43 Keelung Road Section 4 Taipei 10607 Taiwan Department of Food Science National Taiwan Ocean University No. 2 Pei-Ning Road Keelung 20224 Taiwan School of Food Safety Taipei Medical University 250 Wu-Hsing Street Taipei 11031 Taiwan TMU Research Center for Digestive Medicine Taipei Medical University 250 Wu-Hsing Street Taipei 11031 Taiwan Research Center of Biomedical Device Taipei Medical University 250 Wu-Hsing Street Taipei 11031 Taiwan

Bacterial cellulose (BC) is a biodegradable nanoscale film produced by microorganisms, which possesses great mechanical properties and biocompatibility. In this study, we produced foaming BC (FBC) utilizing foam medium with different concentrations of agar. In addition, carvacrol was loaded into the agar/FBC to establish active packaging material. Evaluation by characterization tests indicated that agar/FBC provided lower crystallinity (59.8%∼71.4%) and a high swelling ability (94.7%∼97.9%) compared to BC (92.2% and 96.1%). The 1.5% agar/FBC with carvacrol group exhibited the significantly highest antimicrobial properties against Escherichia coli and Staph.lococcus aureus. Moreover, release measurements showed that greater agar addition contributed to higher protein and carvacrol release extents out of the film. Finally, a sea bass packaging test indicated that carvacrol with 1.5% agar/FBC presented a higher antimicrobial ability against Shewanella putrefaciens, great inhibition of lipid oxidation (67.5%), and a slower spoilage degree (49.8%) which suggested that agar/FBC with carvacrol has potential for active food packaging. © 2024 Elsevier Ltd

关键词： Agar Bacterial cellulose Carvacrol Foaming bacterial cellulose Food packaging Sea bass

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Integration of MRI and somatosensory evoked potentials facilitate diagnosis of spinal cord compression

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Scientific Reports 2023年第1期13卷 1-12页

作者： Sun, Shu-Pin ph.ng, Chun-Ren Tzou, Shey-Cherng Chen, Chang-Mu Ko, Li-Wei International Ph.D. Program in Interdisciplinary Neuroscience (UST) College of Biological Science and Technology National Yang Ming Chiao Tung University 734 Engineering Bldg. 5 1001 Daxue Road Hsinchu 30010 Taiwan Department of Medical Research National Taiwan University Hospital Hsin-Chu Branch Hsinchu 300 Taiwan Institute of Molecular Medicine and Bioengineering National Yang Ming Chiao Tung University Hsinchu 300 Taiwan Department of Surgery College of Medicine and Hospital National Taiwan University No. 7 Zhongshan South Road Taipei 10002 Taiwan Center for Intelligent Drug Systems and Smart Bio-devices (IDS2B) College of Biological Science and Technology National Yang Ming Chiao Tung University Hsinchu 300 Taiwan Institute of Electrical and Control Engineering Department of Electronics and Electrical Engineering National Yang Ming Chiao Tung University Hsinchu 300 Taiwan Department of Biomedical Science and Environment Biology and the Drug Development and Value Creation Research Center Kaohsiung Medical University Kaohsiung 807 Taiwan

This study aimed to integrate magnetic resonance imaging (MRI) and related somatosensory evoked potential (SSEP) features to assist in the diagnosis of spinal cord compression (SCC). MRI scans were graded from 0 to 3 according to the changes in the subarachnoid space and scan signals to confirm differences in SCC levels. The amplitude, latency, and time–frequency analysis (TFA) power of preoperative SSEP features were extracted and the changes were used as standard judgments to detect neurological function changes. Then the patient distribution was quantified according to the SSEP feature changes under the same and different MRI compression grades. Significant differences were found in the amplitude and TFA power between MRI grades. We estimated three degrees of amplitude anomalies and power loss under each MRI grade and found the presence or absence of power loss occurs after abnormal changes in amplitude only. For SCC, few integrated approach combines the advantages of both MRI and evoked potentials. However, integrating the amplitude and TFA power changes of SSEP features with MRI grading can help in the diagnosis and speculate progression of SCC. © 2023, The Author(s).

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Therapeutic targeting of hepatocellular carcinoma cells with antrocinol, a novel, dual-specificity, small-molecule inhibitor of the KRAS and ERK oncogenic signaling pathways

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Chemico-Biological Interactions 2023年第1期370卷 110329页

作者： Hsu, Chia-Hung Weng, Pei-Wei Chen, Ming-Yao Yeh, Chi-Tai Setiawan, Syahru Agung Yadav, Vijesh Kumar Wu, Alexander T.H. Tzeng, david T.W. Gong, Jian-Xian Yang, Zhen Tzeng, Yew-Min Department of Emergency Medicine Shuang Ho Hospital Taipei Medical University New Taipei City 23561 Taiwan Graduate Institute of Injury Prevention and Control College of Public Health Taipei Medical University Taipei City 11031 Taiwan Department of Emergency Medicine School of Medicine Taipei Medical University Taipei 11031 Taiwan Department of Orthopaedics School of Medicine College of Medicine Taipei Medical University Taipei 11031 Taiwan Department of Orthopaedics Shuang Ho Hospital Taipei Medical University New Taipei City 23561 Taiwan Graduate Institute of Biomedical Materials and Tissue Engineering College of Biomedical Engineering Taipei Medical University Taipei 11031 Taiwan Division of Gastroenterology and Hepatology Department of Internal Medicine Shuang Ho Hospital New Taipei City 23561 Taiwan Division of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine College of Medicine Taipei Medical University Taipei 11031 Taiwan Continuing Education Program of Food Biotechnology Applications College of Science and Engineering National Taitung University Taitung 95092 Taiwan International Ph.D. Program in Medicine College of Medicine Taipei Medical University Taipei 11031 Taiwan Ph.D. Program of Translational Medicine College of Medical Science and Technology Taipei Medical University Taipei 11031 Taiwan School of Life Sciences The Chinese University of Hong Kong 999077 Hong Kong Lifebit London EC2A 2AP United Kingdom Laboratory of Chemical Genomics School of Chemical Biology and Biotechnology Peking University Shenzhen Graduate School Shenzhen 518055 China State Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education and Beijing National Laboratory for Molecular Science College of Chemistry and Molecular Engineering Peking University Beijing 100871 China Shenzhen Bay Laboratory Shenzhen 518055 China Department of Applied Science National Taitung University Taitung

Until recently, sorafenib has been the only treatment approved by the U.S. Food and drug Administration for patients with advanced hepatocellular carcinoma (HCC). Some patients, however, exhibit resistance to this treatment and subsequently experience cancer progression, recurrence, or death. Therefore, identifying a new alternative treatment for patients with little or no response to sorafenib treatment is vital. In this study, we explored the therapeutic potential and underlying molecular mechanism of antrocinol ((3aS,4R,6aS,10aR)-4-(hydroxymethyl)-7,7-dimethyldecahydro-1H-naph.ho[1,8a-c]furan-1-one) in patients with HCC. The results indicated that antrocinol was more therapeutically effective than antrocin, Stivarga, and sorafenib against HCC cell lines. Antrocinol also substantially suppressed the expression of KRAS-GTP, p-MEK1/2, p-ERK1/2, and p-AKT in the Huh7 cell line. Additionally, antrocinol-induced apoptosis in the Huh7 cell line, inhibited the formation of tumorsph.res, and suppressed the expression of cancer stem cell markers Cd133, KLF4, Cd44, OCT4, SOX2, and c-Myc. Animal studies revealed that antrocinol alone considerably suppressed tumor growth in nonobese diabetic/severe combined immunodeficient mice inoculated with Huh7 tumorsph.res. It also synergistically enhanced the anticancer effect of sorafenib, resulting in enhanced suppression of tumor growth (p < 0.001) and tumorsph.re formation (p < 0.001). In tumor samples resected from mice treated with antrocinol alone or in combination with sorafenib, immunohistochemical analysis revealed an increase in BAX expression and a decrease in ERK and AKT protein expression. To the best of our knowledge, this is the first report of the anti-HCC activity of antrocinol. With its higher therapeutic efficacy than that of sorafenib, antrocinol is a candidate drug for patients with HCC who demonstrate little or no response to sorafenib treatment. © 2022 Elsevier B.V.

关键词： Antrocinol Cancer stemness Hepatocellular carcinoma KRAS/AKT/ERK axis Sorafenib

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Review on fate, transport, toxicity and health risk of nanoparticles in natural ecosystems: Emerging challenges in the modern age and solutions toward a sustainable environment

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The science of the total environment 2024年 912卷 169331页

作者： Thien-Khanh Tran Minh-Ky Nguyen Chitsan Lin Tuan-dung Hoang Thanh-Cong Nguyen Aasif Mohmad Lone Akhil Pradiprao Khedulkar Mohamed S Gaballah Jagpreet Singh W Jin Chung d duc Nguyen Advanced Applied Sciences Research Group Dong Nai Technology University Bien Hoa City 76100 Viet Nam Faculty of Technology Dong Nai Technology University Bien Hoa City 76100 Viet Nam. Faculty of Environment and Natural Resources Nong Lam University Hamlet 6 Linh Trung Ward Thu Duc City Ho Chi Minh City 700000 Viet Nam Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan. Electronic address: nmky@hcmuaf.edu.vn. Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan Department of Marine Environmental Engineering National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan. School of Chemistry and Life Science Hanoi University of Science and Technology No. 1 Dai Co Viet Hai Ba Trung Hanoi 100000 Viet Nam Vietnam National University Hanoi VNU Town Hoa Lac Thach That District Hanoi 155500 Viet Nam. Department of Civil Engineering Manipal Institute of Technology Manipal Academy of Higher Education Manipal 576104 Karnataka India. Department of Biomedical Engineering and Environmental Science National Tsing Hua University Hsinchu 30013 Taiwan. CAS Key Laboratory of Urban Pollutant Conversion Department of Environmental Science and Engineering University of Science and Technology of China Hefei 230026 China School of Engineering and Technology Central Michigan University Mt. Pleasant MI 48859 USA. Department of Chemistry University Centre for Research and Development Chandigarh University Gharuan Mohali 140413 India. Department of Civil & Energy System Engineering Kyonggi University Suwon 16227 South Korea. Department of Civil & Energy System Engineering Kyonggi University Suwon 16227 South Korea Institute of Applied Technology and Sustainable Development Nguyen Tat Thanh University Ho Chi Minh City 700000 Viet Nam. Electronic address: nguyensyduc@gmail.com.

In today's era, nanoparticles (NPs) have become an integral part of human life, finding extensive applications in various fields of science, ph.rmacy, medicine, industry, electronics, and communication. The increasing popularity of NP usage worldwide is a testament to their tremendous potential. However, the widespread deployment of NPs unavoidably leads to their release into the environmental matrices, resulting in persistence in ecosystems and bioaccumulation in organisms. Understanding the environmental behavior of NPs poses a significant challenge due to their nanoscale size. Given the current environmental releases of NPs, known negative consequences, and the limited knowledge available for risk management, comprehending the toxicity of NPs in ecosystems is both awaiting and crucial. The present review aims to unravel the potential environmental influences of nano-scaled materials, and provides in-depth inferences of the current knowledge and understanding in this field. The review comprehensively summarizes the sources, fate, transport, toxicity, health risks, and remediation solutions associated with NP pollution in aquatic and soil ecosystems. Furthermore, it addresses the knowledge gaps and outlines further investigation priorities for the sustainable control of NP pollution in these environments. By gaining a holistic understanding of these aspects, we can work toward ensuring the responsible and sustainable use of NPs in today's fast-growing world.

关键词： Bioavailability Fate and transport Nanosized particles Nanotoxicology Silver nanoparticles Toxicity

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Ultrafast circuit protection for unmanned systems

Ultrafast circuit protection for unmanned systems

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2019 International Conference on Communications, Information System, and Computer engineering, CISCE 2019

作者： Kao, Chih-Hong Huang, Sy-Ruen He, Bo-Rong Lin, Hsiung-Cheng School of Computer Science Minnan Normal University Lab of Granular Computing ZhangZhou Fujjan China Department of Electrical Engineering Feng Chia University Taichung Taiwan Ph.D. Program of Electrical and Communications Engineering Feng Chia University Taichung Taiwan Department of Electrical Engineering Chin-Yi University of Technology Taichung Taiwan

ISBN: (纸本)9781728136813

With increasing dependence on precision electronic equipment, self-protection is becoming essential. The protection circuits commonly used before were fuses and circuit breakers which, however, they are not enough for the current need of high-speed protection circuits and automated engineering logic. In this paper, we develop a new ultrahigh-speed protection circuit, which is over exceeded 20 times faster than traditional circuits and has the ability to self-recover when any failure occurs. With the new circuit developed, it is not necessary to do manual restart and will meet the future needs of protection for electronic precision equipment. This design provides greater convenience and reliability for the unmanned equipment for the future. © 2019 IEEE.

关键词： Timing circuits

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Improving the Concentration of Students With Attention deficit Hyperactivity disorder and Autism Spectrum disorder: Electroenceph.lograph.c Analysis on the Effect of Learning Activity Interventions

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International Journal of Intelligent Technologies & Applied Statistics 2020年第1期13卷 49-63页

作者： Ming-Hseuh Tsai Sy-Ruen Huang Shao-Chin Chang Yu-Ling Lo Yun-Chieh Lu Research Center for Education Systems and Policy National Academy f or Educational Research New Taipei City Taiwan Chung Chou University of Science and Technology Changhua County Taiwan Ph.D. Program of Electrical and Communications Engineering Feng-Chia University Taichung City Taiwan Department of Early Childhood Education Asia University Taichung City Taiwan

This study examined whether the learning concentration of students with attention deficit hyperactivity disorder (AdHd) or autism spectrum disorder (ASd) can be improved through participation in one-on-one learning activities. A total of 13 students with AdHd or ASd were recruited to participate in various weekly one-on-one learning activities, in an effort to improve the concentration of students with special needs. Brainwave data were collected through electroenceph.lograph. and analyzed to explore students' concentration performance in different learning activities. To achieve the objective of this study, a multi-baseline design (ABAB), a type of single-subject design method, was employed. The experiment spanned 21 weeks, covering a fall and a spring semester: the first three weeks were defined as the 1st baseline ph.se, the 4th to 10th weeks as the 1st experimental ph.se, the 11th to 13th weeks as the 2nd baseline ph.se, and the 14th to 21th weeks as the 2nd experimental ph.se. The learning activities took place in the morning self-study period once a week, and the experiment was only suspended during two of the weeks because of school events. The purpose of the two baseline ph.ses was to collect students' brainwave data. Students' brainwaves were measured for two minutes under two scenarios; first, while they were relaxed with eyes looking straight ahead; second, they were reading a passage. The purpose of the two experimental ph.ses was to gradually enhance students' concentration by training them to perceive their own emotions through brainwave lamps. Initial results yielded different brainwave data for students with different types of disorders. After participating in the training on learning concentration, some students demonstrated improved concentration; however, after the 2nd experimental ph.se, students' concentration declined. The reason was that the activities in both experimental ph.ses were identical, and thus, they no longer provoked students' inte

关键词： Attention def icit hyperactivity disorder (AdHd) Autism spectrum disorder (ASd) Brainwave test Concentration

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Immobilization of poly(hexamethylene biguanide) to cellulose acetate- and cellulose-based nanofiber membranes for antibacterial and cytotoxic studies

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Biochemical engineering Journal 2024年 205卷

作者： dinh Thi My Huong Chi-Yun Wang Pin-Yi Chen Chien Wei Ooi Xue Er Crystal Thew Bing-Lan Liu Chen-Yaw Chiu Shen-Long Tsai Kuei-Hsiang Chen Yu-Kaung Chang Department Chemical Technology and Environment University of Technology and Education the University of Da Nang Da Nang City Viet Nam Department Chemical Engineering/ Graduate School of Biochemical Engineering Ming Chi University of Technology New Taipei City 243303 Taiwan Department Chemical Engineering National Taiwan University of Science and Technology Taipei City 10607 Taiwan International Ph.D. Program in Innovative Technology of Biomedical Engineering and Medical Devices Ming Chi University of Technology New Taipei City 243303 Taiwan Bone and Joint Research Centre Chang Gung Memorial Hospital Taoyuan City 333423 Taiwan Research Center for Intelligent Medical Devices Ming Chi University of Technology New Taipei City 243303 Taiwan Chemical Engineering Department School of Engineering Monash University Malaysia Jalan Lagoon Selatan Bandar Sunway Selangor 47500 Malaysia Advanced Engineering Platform School of Engineering Monash University Malaysia Jalan Lagoon Selatan 47500 Bandar Sunway Selangor Malaysia Department of Applied Chemistry Chaoyang University of Technology Taichung 413310 Taiwan Department of Chemical Engineering and Materials Science Yuan Ze University Zhongli Dist Taoyuan City 320315 Taiwan

To develop the environmental antibacterial membrane, the ph.sical attachments of poly (hexamethylene biguanide) hydrochloride (ph.B) on the cellulose acetate (CA) and regenerated cellulose (RC) electrospun nanofiber membranes were employed. The immobilization of ph.B increased the antibacterial efficacy ( AE , %) of nanofiber membranes from 65.67% to approximately 86.13% for CA-ph.B and from 35.09% to approximately 100% for RC-ph.B. The results of the chemical and ph.sical characteristics indicate that the degree of deacetylation of CA nanofiber, the surface charge of the nanofiber, and the density of ph.B immobilized onto the nanofiber primarily affect the antibacterial efficacy. The use of mathematical models, such as the Temkin equilibrium model for ph.B immobilization and the Monod-type model for the relationship between antibacterial activity and immobilization density of ph.B provides a deeper understanding of the interactions and kinetics involved. The rapid achievement of ∼100% AE after only 10 min of contact with Escherichia coli ( E. coli ) is a notable finding, indicating the quick and efficient antibacterial action of RC-ph.B nanofiber membranes. Furthermore, maintaining approximately 100% AE after 20 days of storage underscores the long-term stability of ph.B immobilized on RC nanofiber membranes. The findings suggest that RC-ph.B holds great promise as an antibacterial material for biomedical applications, food packaging industries, and filtration or treatment of water.

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